WISER is a system developed by the National Library of Medicine that provides first responders with information on hazardous substances. It contains data on chemicals, biologicals, and radiologicals pulled from the Hazardous Substances Data Bank. Users can search for a substance by name or identifier and access profile-tailored data on its identification, physical characteristics, health effects, and containment from a substance list or data page. Profiles for emergency responders, Hazmat specialists, and EMS specialists determine which hotlinks are prioritized in the data presented.