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ACPAcademy Cardiology
STEMI, N-STEMI, and
everything else
Ada County Paramedics
Section 5
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April 2008
Understanding the ST
segment
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
Measuring ST Changes
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• Baseline is correctly determined by finding the T-P to T-P
segment. (If TP not measureable, then preceeding P-R interval
can be used.)
• ST changes are measured 0.08 sec after the “J-point”.
• Changes must be present in 2 or more leads of a “lead group”
to be significant.
• ST elevation or depression of 1 mm or greater in frontal plane
leads is considered significant.
• ST elevation or depression of 2mm or greater in precordial
leads is considered significant.
• ST elevation of 0.5mm or greater in R precordial leads is
considered significant.
T-wave Changes in Ischemia
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• Appear within seconds of onset of AMI
• Appear over zone of ischemia
• May be tall and or deeply inverted depending
on location of ischemia
• Symmetry is important finding in ischemia
• Are associated with prolonged QT interval
• Often associated with ST depression
T-Wave Changes in Ischemia
Peaked, Symmetrical T-Waves
ACPAcademy Section 5: Advanced Clinical Education Cardiology
T-wave changes in Ischemia
Inverted T-waves
ACPAcademy Section 5: Advanced Clinical Education Cardiology
T-Wave Changes In Ischemia
Tall, symmetrical T-Waves With ST Elevation
Section 5: Advanced Clinical Education Card
ACPAcademy iology
ST Depression in Ischemia
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• ST depression is a sign of myocardial
ischemia and can appear in setting of
ischemia from any cause.
• Onset is usually within first hour of AMI, or
more rapidly in other causes of ischemia.
• Often associated with T-wave changes
• Can resolved rapidly with reversal of
ischemia.
• May persist in setting of AMI.
• Mimics include: Coronary artery spasm, acute
pericarditis, ventricular aneurysm.
Types of ST Depression
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ST Elevation in AMI
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• Abnormal ST elevation is an ECG sign of
myocardial injury.
• Usually occur within 20-40minutes following onset of
infarction.
• ST Elevation mimics: pericarditis, early
repolarization, LVH with strain pattern.
Reciprocal Changes?
• Reciprocal ST segment
depression: In the setting of STE
AMI, ST segment depression located
in leads distant from the infarction is
termed reciprocal change or
reciprocal ST segment depression.
• Reciprocal change is useful
– diagnostically— its presence strongly
suggests AMI
– prognostically— patients with such a
finding have larger infarcts, lower
resultant ejection fractions, and
higher rates of death.
ACPAcademy Section 5: Advanced Clinical Education Cardiology
S-T changes and their location?
ACPAcademy Section 5: Advanced Clinical Education Cardiology
Cardiac Anatomy in Relation to
Coronary Artery
Right
coronary
artery
Septal wall
ACP Academy V1-V2
Anterior wall
V3-V4
Left main
coronary
artery
Circumflex
artery
Left anterior
descending artery
Lateral wall
I, aVL, V5-V6
Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
Inferior MI
ACPAcademy Cardiology
NOTE 1: Inferior wall
supplied by either the right
(85% to 90% of people) or
left coronary artery.
NOTE 2: If there is acute
injury in inferior leads
(II, III, aVF), unknown
whether left or right
coronary artery is blocked.
NOTE 3: KEY — you
must obtain a RIGHT-
SIDED ECG at once.
Posterior View of the Heart
HOW TO GET
RIGHT-SIDED ECG?
Leads II, III, aVF
Lateral wall
Inferior wall
Right coronary
artery
Posterior
descending
Section 5: Advance
a
d
r
Cl
t
in
eic
r
a
y
l Education
Posterior
wall
Circumflex
artery
(from left
coronary
artery)
Right Ventricular Infarction
• Inferior lead changes ➨ RV infarction?
–Use lead V4R (ST elevation >1 mm)
• Clinical significance:
–Increased mortality
–Preload dependence
• Vasodilators (Nitrates, MSO4) may cause severe
hypotension
• What is management of RV infarction?
–Increase PRELOAD!! (FLUIDS)
ACPAcademy Section 5: Advanced Clinical Education Cardiology
STEMI, N-STEMI, and STEMI
Mimics
ACPAcademy Section 5: Advanced Clinical Education Cardiology
Three “I”s
• Ischemia
• Injury
• Infarction
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACUTE CORONARY SYNDROMES
ST elevation
Unstable NSTEMI
angina
STEMI
Spectrum of CAD
No ST elevation
Stable
angina
CAD = coronary artery disease; NSTEMI = non-ST-segment elevation myocardial infarction;
STEMI = ST-segment-elevation myocardial infarction.
Source (Photos): Davies MJ. Heart. 2000;83:361-366.
ACPAcademy Section 5: Advanced Clinical Education Cardiology
STEMI Mimics
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• Things that make you go … HMMMM
• Things that look (at first glance) Like a
STEMI or other MI pattern, but are NOT.
– Increase “false positive rates”
• Still may be deadly serious conditions
The basics of doing the 12
lead
ACPAcademy Section 5: Advanced Clinical Education Cardiology
The Basic 12 Lead
ACPAcademy Section 5: Advanced Clinical Education Cardiology
Lead Placement for a
Right-sided ECG
ACPAcademy Section 5: Advanced Clinical Education Cardiology
The importance of serial 12 leads
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
STEMI MIMICS
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
Most common causes of STEMI
mistakes
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• RBBB/LBBB
• Pericarditis
• LVH
• Electrolyte Imbalances
• Drug Effects
Bundle Branch/Fascicular
Blocks
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• LBBB always indicates cardiac disease or injury.
• Just not always ACUTE injury
• Just not always MI, other “Mimics” can also cause BBB
• “Making the diagnosis of acute infarction
in the presence of left bundle-branch block
can be problematic…”
– PROBLEM: Patients with (suspected new)
LBBB tend to be REALLY BAD MI’s.
Bundle Branch/Fascicular Blocks
Right Bundle Branch Block
• Do not rely on presence of “rabbit ears”
for diagnosis of RBBB. Will miss many
RBBBs.
ACPAcademy Section 5: Advanced Clinical Education Cardiology
AMI with BB?
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• AMI should be no problem
• RBBB does not change S-T segment
alterations
• LBBB can make things more interesting
Again with the serial ECGs???
• Even though the
LBBB makes initial
ST evaluation difficult,
the serial changes
noted make this
diagnostic for MI.
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
STEMI Mimics
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• Pericarditis
1. No reciprocal changes. There will only be
S-T elevation, no depression.
2. The myocardium is not involved. No
changes will be noted to the QRS complex.
3. Changes isolated to the S-T-T waves
ACPAcademy Section 5: Advanced Clinical Education Cardiology
ACPAcademy Section 5: Advanced Clinical Education Cardiology
STEMI Mimics
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• Hyperkalemia
– Progressive changes to de- & repolarization
– T wave peaks, then widens/flattens
– PR interval prolongs, and P wave flattens
– QRS widens also
ACP Academy Section 5: Advanced Clinical Education Cardiology
P otassiu m Level: 6.1 mEq/L
ACP Academy Section 5: Advanced Clinical Education Cardiology
P otassiu m Level: 7.2 mEq/L
P otassiu m Level: 9.1 m Eq/L
ACPAcademy Section 5: Advanced Clinical Education Cardiology
STEMI Mimics
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• Hypokalemia
– ST depression with prominent U-waves
– Prolonged repolarization
– T waves flatten
– Can mimic reciprocal changes
Potassium Level: 2.5 mEq/L
ACPAcademy Section 5: Advanced Clinical Education Cardiology
Potassium Level: 1.5 mEq/L
ACPAcademy Section 5: Advanced Clinical Education Cardiology
Potassium Level: 0.9 mEq/L
ACPAcademy Section 5: Advanced Clinical Education Cardiology
STEMI Mimics
ACPAcademy Section 5: Advanced Clinical Education Cardiology
• Cardiac Glycosides-Digoxin
– Digitalis effect-”scooped” ST segment
• Anti-dysrhythmic agents
– Based on where they work
– QT prolongation is common
• Psychotropic agents (i.e.TCA’s)
– Increase QRS duration
– Lengthen QT interval
ACPAcademy Section 5: Advanced Clinical Education Cardiology

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ISCHEMIA.pptx

  • 1. ACPAcademy Cardiology STEMI, N-STEMI, and everything else Ada County Paramedics Section 5 B :lo A cd k va T n rc ae in din Cg linical Education April 2008
  • 2. Understanding the ST segment ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 3. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 4. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 5. Measuring ST Changes ACPAcademy Section 5: Advanced Clinical Education Cardiology • Baseline is correctly determined by finding the T-P to T-P segment. (If TP not measureable, then preceeding P-R interval can be used.) • ST changes are measured 0.08 sec after the “J-point”. • Changes must be present in 2 or more leads of a “lead group” to be significant. • ST elevation or depression of 1 mm or greater in frontal plane leads is considered significant. • ST elevation or depression of 2mm or greater in precordial leads is considered significant. • ST elevation of 0.5mm or greater in R precordial leads is considered significant.
  • 6. T-wave Changes in Ischemia ACPAcademy Section 5: Advanced Clinical Education Cardiology • Appear within seconds of onset of AMI • Appear over zone of ischemia • May be tall and or deeply inverted depending on location of ischemia • Symmetry is important finding in ischemia • Are associated with prolonged QT interval • Often associated with ST depression
  • 7. T-Wave Changes in Ischemia Peaked, Symmetrical T-Waves ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 8. T-wave changes in Ischemia Inverted T-waves ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 9. T-Wave Changes In Ischemia Tall, symmetrical T-Waves With ST Elevation Section 5: Advanced Clinical Education Card ACPAcademy iology
  • 10. ST Depression in Ischemia ACPAcademy Section 5: Advanced Clinical Education Cardiology • ST depression is a sign of myocardial ischemia and can appear in setting of ischemia from any cause. • Onset is usually within first hour of AMI, or more rapidly in other causes of ischemia. • Often associated with T-wave changes • Can resolved rapidly with reversal of ischemia. • May persist in setting of AMI. • Mimics include: Coronary artery spasm, acute pericarditis, ventricular aneurysm.
  • 11. Types of ST Depression ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 12. ST Elevation in AMI ACPAcademy Section 5: Advanced Clinical Education Cardiology • Abnormal ST elevation is an ECG sign of myocardial injury. • Usually occur within 20-40minutes following onset of infarction. • ST Elevation mimics: pericarditis, early repolarization, LVH with strain pattern.
  • 13. Reciprocal Changes? • Reciprocal ST segment depression: In the setting of STE AMI, ST segment depression located in leads distant from the infarction is termed reciprocal change or reciprocal ST segment depression. • Reciprocal change is useful – diagnostically— its presence strongly suggests AMI – prognostically— patients with such a finding have larger infarcts, lower resultant ejection fractions, and higher rates of death. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 14. S-T changes and their location? ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 15. Cardiac Anatomy in Relation to Coronary Artery Right coronary artery Septal wall ACP Academy V1-V2 Anterior wall V3-V4 Left main coronary artery Circumflex artery Left anterior descending artery Lateral wall I, aVL, V5-V6 Section 5: Advanced Clinical Education Cardiology
  • 16. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 17. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 18. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 19. ACPAcademy Section 5: Advanced Clinical Education Cardiology Inferior MI
  • 20. ACPAcademy Cardiology NOTE 1: Inferior wall supplied by either the right (85% to 90% of people) or left coronary artery. NOTE 2: If there is acute injury in inferior leads (II, III, aVF), unknown whether left or right coronary artery is blocked. NOTE 3: KEY — you must obtain a RIGHT- SIDED ECG at once. Posterior View of the Heart HOW TO GET RIGHT-SIDED ECG? Leads II, III, aVF Lateral wall Inferior wall Right coronary artery Posterior descending Section 5: Advance a d r Cl t in eic r a y l Education Posterior wall Circumflex artery (from left coronary artery)
  • 21. Right Ventricular Infarction • Inferior lead changes ➨ RV infarction? –Use lead V4R (ST elevation >1 mm) • Clinical significance: –Increased mortality –Preload dependence • Vasodilators (Nitrates, MSO4) may cause severe hypotension • What is management of RV infarction? –Increase PRELOAD!! (FLUIDS) ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 22. STEMI, N-STEMI, and STEMI Mimics ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 23. Three “I”s • Ischemia • Injury • Infarction ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 24. ACUTE CORONARY SYNDROMES ST elevation Unstable NSTEMI angina STEMI Spectrum of CAD No ST elevation Stable angina CAD = coronary artery disease; NSTEMI = non-ST-segment elevation myocardial infarction; STEMI = ST-segment-elevation myocardial infarction. Source (Photos): Davies MJ. Heart. 2000;83:361-366. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 25. STEMI Mimics ACPAcademy Section 5: Advanced Clinical Education Cardiology • Things that make you go … HMMMM • Things that look (at first glance) Like a STEMI or other MI pattern, but are NOT. – Increase “false positive rates” • Still may be deadly serious conditions
  • 26. The basics of doing the 12 lead ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 27. The Basic 12 Lead ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 28. Lead Placement for a Right-sided ECG ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 29. The importance of serial 12 leads ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 30. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 31. STEMI MIMICS ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 32. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 33. Most common causes of STEMI mistakes ACPAcademy Section 5: Advanced Clinical Education Cardiology • RBBB/LBBB • Pericarditis • LVH • Electrolyte Imbalances • Drug Effects
  • 34. Bundle Branch/Fascicular Blocks ACPAcademy Section 5: Advanced Clinical Education Cardiology • LBBB always indicates cardiac disease or injury. • Just not always ACUTE injury • Just not always MI, other “Mimics” can also cause BBB • “Making the diagnosis of acute infarction in the presence of left bundle-branch block can be problematic…” – PROBLEM: Patients with (suspected new) LBBB tend to be REALLY BAD MI’s.
  • 35. Bundle Branch/Fascicular Blocks Right Bundle Branch Block • Do not rely on presence of “rabbit ears” for diagnosis of RBBB. Will miss many RBBBs. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 36. AMI with BB? ACPAcademy Section 5: Advanced Clinical Education Cardiology • AMI should be no problem • RBBB does not change S-T segment alterations • LBBB can make things more interesting
  • 37. Again with the serial ECGs??? • Even though the LBBB makes initial ST evaluation difficult, the serial changes noted make this diagnostic for MI. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 38. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 39. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 40. STEMI Mimics ACPAcademy Section 5: Advanced Clinical Education Cardiology • Pericarditis 1. No reciprocal changes. There will only be S-T elevation, no depression. 2. The myocardium is not involved. No changes will be noted to the QRS complex. 3. Changes isolated to the S-T-T waves
  • 41. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 42. ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 43. STEMI Mimics ACPAcademy Section 5: Advanced Clinical Education Cardiology • Hyperkalemia – Progressive changes to de- & repolarization – T wave peaks, then widens/flattens – PR interval prolongs, and P wave flattens – QRS widens also
  • 44. ACP Academy Section 5: Advanced Clinical Education Cardiology P otassiu m Level: 6.1 mEq/L
  • 45. ACP Academy Section 5: Advanced Clinical Education Cardiology P otassiu m Level: 7.2 mEq/L
  • 46. P otassiu m Level: 9.1 m Eq/L ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 47. STEMI Mimics ACPAcademy Section 5: Advanced Clinical Education Cardiology • Hypokalemia – ST depression with prominent U-waves – Prolonged repolarization – T waves flatten – Can mimic reciprocal changes
  • 48. Potassium Level: 2.5 mEq/L ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 49. Potassium Level: 1.5 mEq/L ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 50. Potassium Level: 0.9 mEq/L ACPAcademy Section 5: Advanced Clinical Education Cardiology
  • 51. STEMI Mimics ACPAcademy Section 5: Advanced Clinical Education Cardiology • Cardiac Glycosides-Digoxin – Digitalis effect-”scooped” ST segment • Anti-dysrhythmic agents – Based on where they work – QT prolongation is common • Psychotropic agents (i.e.TCA’s) – Increase QRS duration – Lengthen QT interval
  • 52. ACPAcademy Section 5: Advanced Clinical Education Cardiology