Funded in part by the NIH, Reloadable Incentive Card (RIC), helps clinical trials increase subject retention, reduce pilferage and increase compliance.

1. (c) Calance Corporation 2010, Company Confidential
Reloadable Incentive Card (RIC)

2. Summary
 For longitudinal field studies involving human subjects, successfully
tracking, locating and following up with a representative sample of
subjects is a challenge.
 Nearly one-third of the subjects are lost to attrition within 36 months1
 Follow-up rates below 80% have been shown to produce dramatically
biased estimates2
 RIC provides researchers and interviewers a secured system to track
the subjects, update locater information and provide incentives.
 Separation of private information from incentives management.
(c) Calance Corporation 2010, Company Confidential
1.Hansen, Tobler & Graham, 1990
2. Nemes et al., 2002

3. Challenges in Clinical Studies
 Burden on the research subjects to remember follow-up appointments
 No mechanism for instant reward for positive actions
 Use it or lose it gift cards are not widely accepted. No way to replace a
lost gift card.
 Administrative burdens on the study for securing cash or cash
equivalent gift cards
 Social stigma associated with food stamps and other gift certificates
(c) Calance Corporation 2010, Company Confidential

4. Reloadable Incentive Card (RIC) system
(c) Calance Corporation 2010, Company Confidential

5. Features
 An intuitive web application designed for researchers and clinics involved in
studies with human subjects. The application has been designed in
collaboration with researchers involved with clinical studies.
 Automates the tracking and locating of subjects and the administration of
incentives.
 Brings together key elements in human study administration that are
currently managed in isolation - subject engagement, subject tracking,
follow-up events, and incentives.
 RIC offers immediate association between action and reward
 RIC can differentia the monetary value of the reward for each act.
 MasterCard/Visa branded custom cards are widely accepted
 Future release plans includes, integration between an IVR system for
automated incentives transfer on weekly location update, rule based
calendar generation for follow-up and incentives calculations, support of
additional databases.
(c) Calance Corporation 2010, Company Confidential

6. Subjects’ Experience with RIC
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7. Workflow
(c) Calance Corporation 2010, Company Confidential
Setup Study
Setup
Subjects
Subject &
Incentive Management
 Meta data entry
for studies
 Follow-up
calendar setup
 Funding of
source account
 Logical grouping
 Authorizations
Auditing and Reporting
 De-sensitize
identifying
information
 Create a link
between
research
database and
RIC
 Link incentive
card to subjects
 Update locater
information
 Incentive
transfer
 Replace lost
cards
 Generate follow-
up reports

8. Study Protocol Setup
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9. Import Subjects Wizard
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10. Search Subjects Screen
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11. Update Locater Information Screen
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12. Add an Incentive Card
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13. Real Time Lost Card Replacement
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14. Real Time Incentives Transfer
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15. Administrative Screens
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16. Architecture
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 Architected using
industry standard
SOA principles
 J2EE, MySQL,
Apache
 Platform
independent –
Linux or Windows
 Can import data
from SQL Server,
MySQL, Oracle.