Hepatitisrev

HEPATITIS Medicina Interna CESAR GARCIA CASALLAS 2011

HEPATITIS A B C D E Nombre Común Infecciosa Suero Postransfusión no B Agente delta Enterica no A Estructura Picornavirus Hepadnavirus Flavivirus Viroide Calcivirus Transmisión Fecal Oral Parenteral, Sexual Parenteral, Sexual Parenteral, Sexual Fecal Oral Inicio Súbito Progresivo Progresivo Súbito Súbito Periodo de incubación (días) 15 – 20 45 - 160 14 - 180 15 - 64 15 – 50 Mortalidad <0.5% 1 – 2% 4% Muy elevada 1 – 2% emb 20% Cronicidad No Si Si Si No Enfermedades Asociadas ---- Carcinoma hepatocelular, cirrosis Carcinoma hepatocelular, cirrosis Cirrosis, hepatitis fulminante ----

Causas de hepatitis viral ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Hepatitis parasitaria ,[object Object],[object Object],[object Object],[object Object],[object Object]

Hepatitis bacterianas ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HEPATITIS A ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Hepatology, 2006 43, S1, S164-S172

HEPATITIS A ,[object Object],Hepatology, 2006 43, S1, S164-S172 7500 Nucleótidos

HEPATITIS A ,[object Object],Hepatology, 2006 43, S1, S164-S172

Endemiología Frec Enferm Edad de Infx Modelo de Trasmisión Alta Baja a Alta Infancia Persona a persona; Moderada Alta Adolesc Adulto Joven Persona a persona; Alimentos y agua Baja Baja Adulto Joven Persona a persona; Alimentos y agua Muy Baja Muy Baja Adultos Viajeros; Modelo de Transmisión de Hepatitis A

HEPATITIS A ,[object Object],[object Object],[object Object],[object Object],Hepatology, 2006 43, S1, S164-S172

HEPATITIS A ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Diagnóstico de Lab. ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],Hepatitis A – Características Clinicas

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Prevención Hepatitis A – Globulina Inmune

HEPATITIS B Hepatology, 2006 43, S1, S173-S181

HEPATITIS B ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HEPATITIS B ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Hepatology, 2006 43, S1, S173-S181

Hepatology, 2006 43, S1, S173-S181

Diagnóstico Hepatitis B ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Serología Precoz Aguda Crónica Curación Vacuna Anti-HBc - - + + - Anti-HBe - - - +/- - Anti-HBs - - - + + HBeAg - + + - - HBsAg + + + - - Virus + + + - -

HEPATITIS B ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Hepatology, 2006 43, S1, S173-S181

Tratamiento ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Prevención ,[object Object],[object Object],[object Object]

Hepatitis C ,[object Object],[object Object],[object Object],[object Object],[object Object],Hepatology, 2006 43, S1, S182-S191

Periodo de Incubación: Promedio 6-7 ss Range 2-26 wks Clínica (ictericia): 30-40% (20-30%) Hepatitis Crónica: 70% Infección persistente: 85-100% Inmunidad: No protectora Hepatitis C - Clinical Features Hepatology, 2006 43, S1, S182-S191

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Factores de Riesgo Asociados con Trasmisión Hepatology, 2006 43, S1, S182-S191

Diagnóstico ,[object Object],[object Object],[object Object],Hepatology, 2006 43, S1, S182-S191

Tratamiento ,[object Object],[object Object]

[object Object],[object Object],[object Object],Prevención de la Hepatitis C

Hepatitis viral tipo delta ,[object Object],[object Object],[object Object],[object Object]

Virus de la hepatitis D (Agente delta) ,[object Object]

Hepatitis viral tipo E ,[object Object],[object Object],[object Object]

Sospecha de hepatitis viral: pruebas serológicas iniciales ,[object Object],[object Object],[object Object],[object Object]

Sospecha de hepatitis viral ,[object Object]

MARCADORES SEROLÓGICOS HBV ,[object Object],[object Object],[object Object]

MARCADORES SEROLÓGICOS HBV ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Períodos de incubación ,[object Object],[object Object],[object Object],[object Object],[object Object]

Períodos de transmisibilidad ,[object Object],[object Object],[object Object],[object Object]

Inmunización ,[object Object],[object Object],[object Object]

Tratamiento ,[object Object],[object Object],[object Object]

BIBLIOGRAFIA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Hepatitisrev

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