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- TIF B cells and T cells are able to alter their genome. What kind of diversity does this give the
variable region? Why would dedicating a part of our genome for this variability not be possible?
- Complete immunoglobulin genes are generated by the of separate gene segments. What is this
process? - Hypervariable (HV) regions are also known as what? - What segment are CDR1 and
CDR2 located on? Where does the CDR3 region originate from? - What is the CDR3 loop
formed from? - How are light-chain V regions constructed?

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