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  • 1. VII. PHYSIOLOGY ETIOLOGY CONTRIBUTING FACTORS COITUS IN-VITRO Mature sperm Ability of the sperm to reach the ovum Ability of the sperm to penetrate zona pelucida Maturation of ova Ejaculates semen man woman 400 million An ovulated ovum ruptures in the ovary spermatozoa Releases ova Deposited to vagina capacitation Unfertilized ova Dissolves the layer of cells protecting ova Hyaluronidase enzyme Penetrates SPERMATOZOON the ova enters Intermingling of haploid paternal and maternal chromosomes ↑ Estrogen FERTILIZATION Amenorrhea FSH suppression ZYGOTE FORMATION Peristaltic wave + fimbriae Another 3-4 days the morula MITOTIC CELL DIVISIONS (CLEAVAGE) continues to multiply as flash free in the uterine cavity First 2 cells were developed (24⁰) MORULA FORMATION
  • 2. Reaches 100 cells BLASTOCYST TROPHOBLAST EMBRYOBLAST Sheds the last residues of corona radiate and zona pelucida syncytiotrophoblast cytotrophoblast Chorionic villi resembles 11th Parts that did not attached Vaginal spotting or 12th day endometrium IMPLANTATION Placental hormone Reaches the uterine endometrium amnion chorion ↓ IgG hCG hPL estrogen progesterone placenta Amniotic sac Fetal membrane ↑ WBC ↑level Umbilical cord N/V Produce phospholipid Mesoderm:  Supporting structures of the body (connective tissue, Initiates formation of prostaglandin Entoderm: bones, cartilage, muscle, Ectoderm:  Lining of pericardial, pleura ligaments and tendons)  CNS(brain and spinal cord and peritoneal cavities  Dentin of teeth  Peripheral nervous system  Lining of the GIT, resp. tract,  Upper portion of the urinary  Skin, hair and nails tonsils, parathyroid, thyroid, system  Mucous membranes of the thymus gland  Reproductive system anus, mouth, and nose  Lower urinary system  Heart, circulatory system  Tooth enamel (bladder and urethra)  Blood cells, lymph vessels  Mammary glands
  • 3. EMBRYONIC Primitive gonadal tissue DEVELOPMENT mesonephric paramesonephric 5-8 weeks Female primitive testes reproductive develops organ FETAL DEVELOPMENT Formation of Not present by testosterone 10th week 1st trimester: 2nd trimester  Length: 7-8cm  Length: 25 cm  Weight: 45g  Weight: 550 g Turns into ovaries 3rd trimester:  Nail beds are forming on fingers.  Meconium is present as far as the  Length: 48-52 cm  Some reflexes, such as Babinski reflex, rectum.  Weight: 3000 g are present.  Active production of lung surfactant  Fetus kicks actively.  Bone ossification centers begin to form. begins.  Fetal hgB begins its conversion to adult  Tooth buds are present.  Eyebrows and eyelashes become well hgB. 12 weeks external  Sex is distinguishable by outward defined.  Vernix Caseosa is fully formed. genital develops appearance.  Pupils are capable of reacting to light.  Fingernails extend over the fingerstips.  Heartbeat is audible through Doppler  Hearing can be demonstrated by  Creases on the soles of the feet cover technology. response to sudden sound. at least two thirds of the surface. Placental ageing S/Sx and Discomforts felt by the Patient
  • 4. Breast tenderness, palmar erythema, Backache due to lumbar lordosis Backache due to lumbar lordosis constipation, hemorrhoids, frequent Dyspnea due to expanding uterus, linea nigra, Dyspnea due to expanding uterus, lightening, urination,abdominal discomfort, leucorrhea, striae gravidarum, quickening, frequent frequent urination, constipation. urination, constipation. food cravings, nausea and vomiting. Labor onset Fetal cortisol production Fetal movement ↓ Progesterone level Braxton hicks contraction False labor pressure on the cervix Stimulates the release of oxytoxin from the posterior pituitary gland Oxytoxin production True labor Engagement of fetus Uterine contraction show Rupture of membranes
  • 5. Acute pain: Blood , mixed with mucus, Pain is felt first in lower takes on a pink tinged back and sweep around stress to the abdomen in a wave. Mechanism of labor DESCENT FLEXION INTERNAL EXTENSION EXTERNAL EXPULSION ROTATION ROTATION EPISIOTOMY NEW BABY GIRL PLACENTAL P 5-30 mins SEPARATION Minimal vaginal bleeding Placental expulsion EPISIORRAPHY Puerperium