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elviraloallo

• 1- Non todo o que está escrito é verdade. Hai
espazos na rede para que poida escribir
calquera. Quen é o autor e onde está escrito?

• 2- Información actualizada. Non podemos
fiarnos de entradas moi antigas que xa
puideron sufrir modificacións. Non se pode
coller o primeiro que aparece, hai que seguir
lendo.

• 3- Temos que comprobar que o que lemos é
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distintas páxinas. Contrastar fontes.

• 4- Distinguir entre obxectivo e subxectivo:
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Podemos obter datos de distintas
publicacións: enciclopedias, xornais, blogs
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Que nos interesa?

• 5- Facer un traballo non é cortar e pegar.
Debemos ler moito, seleccionar a información
e organizala nun documento ben redactado
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e elaborar as nosas conclusións.

• 6- Citar as fontes: indicar de onde obtemos a
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Abstract Objective(s): This study aimed to determine the possible toxicity of Cuo nanoparticles (NPs) on Oncorhynchus mykiss by evaluating hematological parameters. Materials and Methods: Fish were sampled and treated in 4 aquariums containing the concentration ranges of 1, 5, 20 and 100 ppm of CuO NPs. There was one control group (no CuO NPs) and three replicates. The physicochemical properties of water were as follows: the temperature was 22±2 Cº, oxygen saturation was 90.9±0.2%, pH was at 7±0.004 and the concentration of CaCO3 was 270. Results: No mortality was observed after 96 hours of exposure. The analysis of hematological parameters showed that CuO NPs affected the counts of white blood cells, lymphocytes, eosinophils, neutrophils, hematocrits, MCH, MCHC and MCV and did not have any effects on monocytes and hemoglobins. Conclusion: The data showed that the overall hardness (270 ppm) neutralized the lethal effect of copper on O. mykiss and no mortality was recorded.

Effect of CuO nanoparticles on some hematological indices of rainbow trout on...

Nanomedicine Journal (NMJ)

Diapositiva ketty

sulema murillo

Abstract Objecttive(s): Despite the poor mechanical properties of hydroxyapatite, its unique biological properties leads we think about study on improving its properties rather than completely replacing it with other biomaterials. Accordingly, in this study we introduced hydroxyapatite reinforced with hardystonite as a novel bio-nanocompositeand evaluate its in-vitro bioactivity with the aim of developing a mechanically strong and highly porous scaffold for bone tissue engineering applications. Materials and Methods: Natural Hydroxyapatite (NHA)-Hardystonite (HT) nanocomposite with different percentage of HT was synthesized by mechanical activation method and subsequent heating annealing process. This study showed that the addition of HT to HA not only increases the mechanical properties of HA but also improves its bioactivity. Dissolution curves presented in this study indicated that the pH value of SBF solution in the vicinity of HA-HT nanocomposite increases during the first week of experiment and decreases to blood pH at the second weekend. Hardystonite was composed of nano-crystalline structure with approximately diameter 40 nm. Specimens were composed of a blend of pure calcite (CaCO3) (98% purity, Merck), silica amorphous (SiO2) (98% purity, Merck) powder and pure zinc oxide (ZnO) with 50 % wt., 30 %wt and 20 %wt., respectively. These powders were milled by high energy ball mill using ball-to- powder ratio 10:1 and rotation speed of 600 rpm for 5 and 10 h. Then, the mixture mechanical activated has been pressed under 20 MPa. The samples pressed have been heated at 1100 ºC for 3 h in muffle furnace at air atmosphere. X-ray diffraction (XRD), scanning electron microscopy (SEM) and BET performed on the samples to characterize. Results: According to XRD results, the sample milled for 10 h just indicated the hardystonite phase, while the sample milled for 5 h illustrate hardystonite phase along with several phases. Conclusion: In fact, our study indicated that hardystonite powder was composed of nano-crystalline structure, about 40 nm, can be prepared by mechanical activation to use as a new biomaterials for orthopedic applications.

Preparation and characterization of hydroxyapatite reinforced with hardystoni...

Nanomedicine Journal (NMJ)

materi STI

sirajunnasihin

watch 2015 French Motogp GP live

timaktimak

Distintivo Empresa Socialmente Responsable

Perú 2021

Abstract Objective(s): Although viral vectors are considered efficient gene transfer agents, their board application has been limited by toxicity, immunogenicity, mutagenicity and small gene carrying capacity. Non-viral vectors are safe but they suffer from low transfection efficiency. In the present study, polyallylamine (PAA) in two molecular weights (15 and 65 kDa) was modified by alkane derivatives in order to increase transfection activity and to decrease cytotoxicity. Materials and Methods: Modified PAA was synthesized using three alkane derivatives (1-bromobutane, 1-bromohexane and 1-bromodecane) in different grafting percentages (10, 30 and 50). The condensation ability of modified PAA was determined by ethidium bromide test. The prepared polyplexes, complexes of modified PAA and DNA, were characterized by size and zeta potential. Transfection activity of polyplexes was checked in Neuro2A cells. The cytotoxicity of vector was examined in the same cell line. Results: DNA condensation ability of PAA was decreased after modification but modified polymer could still condense DNA at moderate and high carrier to plasmid (C/P) ratios. Most of polyplexes composed of modified polymer had mean size less than 350 nm. They showed a positive zeta potential, but some vectors with high percentage of grafting had negative surface charge. Transfection efficiency was increased by modification of PAA by 1-bromodecane in grafting percentages of 30 and 50%. Modification of polymer reduced polymer cytotoxicity especially in C/P ratio of 2. Conclusion: Results of the present study indicated that modification of PAA with alkane derivatives can help to prepare gene carriers with better transfection activity and less cytotoxicity.

Preparation, characterization and transfection efficiency of nanoparticles co...

Nanomedicine Journal (NMJ)

Proyecto final dpi grupo42

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Effect of CuO nanoparticles on some hematological indices of rainbow trout on...

Diapositiva ketty

Preparation and characterization of hydroxyapatite reinforced with hardystoni...

materi STI

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Distintivo Empresa Socialmente Responsable

Preparation, characterization and transfection efficiency of nanoparticles co...

Proyecto final dpi grupo42

Pescuda na rede

1. PESCUDA NA REDE

2. • 1- Non todo o que está escrito é verdade. Hai espazos na rede para que poida escribir calquera. Quen é o autor e onde está escrito?

3. • 2- Información actualizada. Non podemos fiarnos de entradas moi antigas que xa puideron sufrir modificacións. Non se pode coller o primeiro que aparece, hai que seguir lendo.

4. • 3- Temos que comprobar que o que lemos é fiable.Buscar a mesma información en distintas páxinas. Contrastar fontes.

5. • 4- Distinguir entre obxectivo e subxectivo: artigos de investigación / artigos de opinión. Podemos obter datos de distintas publicacións: enciclopedias, xornais, blogs persoais ou profesionais, organizacións, etc ... Que nos interesa?

6. • 5- Facer un traballo non é cortar e pegar. Debemos ler moito, seleccionar a información e organizala nun documento ben redactado no que debemos sintetizar os datos recollidos e elaborar as nosas conclusións.

7. • 6- Citar as fontes: indicar de onde obtemos a información.

Pescuda na rede

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Pescuda na rede