This document discusses the Efruzher cancer theory and the role of the T3 receptor in carcinogenesis. It explains that cytokines and growth factors can have proliferative or differentiative effects on cells depending on dosage levels, with high doses being proliferative and low/normal doses causing differentiation. The T3 receptor is located in the nucleus and mitochondria, and energy production is an important factor influencing proliferation and differentiation. Cancer cells continuously take high levels of ligand signaling, exhibiting proliferative behavior through aerobic glycolysis rather than mitochondrial oxidative phosphorylation, resulting in broken or low energy generation and unsuccessful transcription expression.

1. “EFRUZHU
CANCER (CARCİNOGENESİS) THEORY”
T3 RECEPTOR AND İMPORTANCE OF CANCER .
DETAİLED COMMENTS 22. = VOİCED 22.
CYTOKİNES-GROWTH FACTORS MAKE PROLİFERATİVE AND
DİFFERENCİATİVE EFFECT ONTO CELL DEPENDENT OF DOSAGE,HİGH
DOSE PROLİFERATİVE,LOW/NORMAL DOSE MAKES
DİFFERENCİATİON.T3 RECEPTOR LOCALİSED İN THE NUCLEUS AND
MİTHOCHONDRİON.ENERGY VERY İMPORTANT CONDİTİON THAT
PROLİFERATİON AND DİFFERENCİATİON.CANCER CELL
CONTİNUOUSLY TAKES LİGAND SİGNALİNG HİGH LEVEL /DOSE SO
DOMİNANTİVE BEHAVİOUR PROLİFERATİVE ACTİONS BUT ENERGY
GENERATİON İN THE AEROBİC GLYCOLYSİS/MİTHOCHONDRİON HAS
BROKEN DOWN OR LOW LEVEL NORMAL DNA SEQUENCE SHOULD
NOT OPPENED(TRANSCRİPTİON EXPRESSİON UNSUCCESSFUL) TO
PRODUCE OXİDATİVE PHOSPHORİLATİON
POLİPEPTİDES,TRANSCİPTİON FACTOR,TRANSPORTER ETC.SO THAT