4. Anxiety disorders in DSM4
Generalized anxiety disorder
Obsessive Compulsive Disorder
Post traumatic stress disorder
Panic disorder
Agoraphobia
Social phobia
Specific phobia
5. Etiology of Anxiety Disorders
Biological
Genetic
first-
degree relatives
are more affected.
Neurological
basal ganglia
limbic system
frontal cortex
Neuro
Physiological
serotonin
6. Etiology of Anxiety Disorders cont.
Psychological
Psycho-analytic
anxiety is a symptom
of unresolved,
unconscious conflicts
Cognitive-behavioural
selective attention
to negative details
Classic conditioning
9. GAD cont.
prevalence 5%
men - women
1 2
Co morbidity 50% have another psychiatric
diagnosis, (major depressive disorder , panic
disorder)
Age of onset 20 - 35
10. GAD Diagnosis ( DSM4 )
A. Excessive anxiety and worry for at least 6 months, about a
number of events or activities (such as work or school
performance).
B. The person finds it difficult to control the worry.
C. three (or more) of the following symptoms
restlessness
being easily fatigued
difficulty concentrating or mind going blank
irritability
muscle tension
sleep disturbance
11. GAD Prognosis
Only one third of patients who have generalized
anxiety disorder seek psychiatric treatment.
Many go to general practitioners, internists,
cardiologists, pulmonary specialists .
generalized anxiety disorder is a chronic
condition that may well be lifelong .
14. OCD clinical features
Obsession
intrusive and inappropriate thoughts, impulses, or
images that are experienced, at some time during the
disturbance, that cause marked anxiety or distress
Compulsion
repetitive behaviors (e.g., hand washing,) or mental acts
(e.g., counting, repeating words) that the person feels
driven to perform in response to an obsession
*
15. OCD cont.
Prevalence
Lifetime prevalence 2 -3%
- men - women
1 1
Co morbidity
Often co-morbid anxiety disorders, (social phobia
25%), depression (67%), eating disorders
Age of onset
20 years
16. OCD Diagnosis ( DSM4 )
A. Either obsessions or compulsions
B. At some point during the course of the
disorder, the person has recognized that the
obsessions or compulsions are excessive or
unreasonable.
17. OCD Prognosis
20 to 30 % of patients have significant
improvement in their symptoms, and 40 to 50 %
have moderate improvement. The remaining 20
to 40 % of patients either remain ill or their
symptoms worsen
21. PTSD cont.
Prevalence
lifetime prevalence of PTSD is estimated to be
about 8%
- men - women
1 2
Co morbidity
75% have depressive disorders, substance-related
disorders, other anxiety disorders
22. PTSD Diagnosis ( DSM4 )
A. Exposure to a traumatic event
B. Re experience
C. Avoidance
D. Hyper arousal
*
23. PTSD Prognosis
The delay can be as short as 1 week or as long as 30
years.
Course
30 % of patients recover completely
40 % continue to have mild symptoms
20 % continue to have moderate symptoms
10 % remain unchanged or become worse.
After 1 year, about 50 %of pat ients will recover.
26. Panic disorder
clinical features
Palpitations, chest pain, choking sensation,
dizziness, breathlessness, tingling in the hands
and feet, sweating, nausea or abdominal distress.
Emotional and behavioural symptoms
Fear of dying, losing control, going mad
Feeling of unreality - depersonalisation
Need to exit situation
*
27. Panic disorder cont.
Prevalence 1% to 5%
men - women
1 2 to 3
Co morbidity
91% have at least another psychiatric disorder
84% with agoraphobia
10% with major depressive disorder.
28. Panic disorder Diagnosis ( DSM4 )
Recurrent panic attacks
1 month of :
concern about having another attack
worry about the implication of the attack
A discrete period of intense fear or
discomfort, in which four (or more) of panic
symptoms developed abruptly and reached a
peak within 10 minutes
29. Panic disorder prognosis
Onset in late adolescence or early adulthood
Panic disorder, in general, is a chronic disorder,
although its course is variable.
30 to 40 % of patients seem to be symptom free.
50 % have symptoms that are sufficiently mild
not to affect their lives significantly.
10 to 20 % continue to have significant
symptoms.
33. Agoraphobia Diagnosis ( DSM4 )
Anxiety about being in places or situations from
which escape might be difficult (or embarrassing) or
in which help may not be available in the event of
having an unexpected or situationally predisposed
panic attack or panic-like symptoms.
The situations are avoided (e.g., travel is restricted) or
else are endured with marked distress or with anxiety
about having a panic attack or panic-like symptoms
34. Agoraphobia prognosis
Most cases of agoraphobia are thought to be
caused by panic disorder. When the panic
disorder is treated, the agoraphobia often
improves with time
37. Clinical features
Social Phobia
Fear of acting in a way that will be embarrassing
or humiliating or appear ridiculous
Feared social situation associated with intense
anxiety and distress - blushing, tremor,butterflies
Leads to avoidance of social situations that
involve e.g., eating, public speaking – isolation
*
38. Social Phobia cont.
Prevalence 2% to 13%
- men - women
1 2
Co morbidity
other anxiety disorders, mood disorders, substance-
related disorders, and bulimia nervosa.
39. Social Phobia( DSM4 )
A marked and persistent fear of one or more
social or performance situations.
The person recognizes that the fear is excessive
or unreasonable ..
Avoidance, interferes significantly with the
person's normal routine
40. Social Phobia prognosis
Social phobia tends to have its onset in late
childhood or early adolescence. Social phobia
tends to be a chronic disorder
46. Clinical features cont.
Specific phobias
Anxiety provoked only in response to a specific
stimulus or situation
Panic attacks can occur
Degree of disability is related to ease or
difficulty of avoiding the feared object
Feared object usually something that posed a
threat at some time in history - animals, storms,
heights, darkness, blood
47. Specific phobias prognosis
As with other anxiety disorders, limited
prospective epidemiological data exist on the
natural course of specific phobia. Because
patients with isolated specific phobias rarely
present for treatment, research on the course of
the disorder in the clinic is limited .
50. Treatment of Anxiety Disorders
1. Antidepressants
- SSRIs - paroxetine, citalopram - can initially
worsen panic attacks
- TCAs - imipramine, clomipramine
2. Benzodiazepines - good short term relief but
high risk of dependency - alprazolam
52. Treatment of Anxiety Disorders
Behavior Therapy
Systematic Desensitization
- Relaxation Training
- Hierarchy Construction
- Desensitization of the Stimulus