This is based on a Harvard-based study published in JAMA https://www.health.harvard.edu/blog/peripheral-artery-disease-often-silent-sometimes-deadly-potentially-preventable-201210245448

1. Source: Peripheral artery disease: often silent, sometimes deadly, potentially preventable,
https://www.health.harvard.edu/blog/peripheral-artery-disease-often-silent-sometimes-deadly-potentially-preventable-201210245448
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Focus on PAD:
Common Health Factors
High Blood Pressure
Diabetes
Smoking
High Cholesterol
45,000 males
followed for 25 years found “big 4” factors
responsible for heart disease and stroke
96%of those diagnosed with PAD had one or more
of these 4 factors
2x risk of PAD for each
additional factor
the longer they had one of more of the 4
factors, the more likely they were to have PAD
16xrisk if patient has all
4 factors
+