The exact mechanism is still being explored and debated
These chemicals are located in energy compartments in the cell called mitochondria. When you stimulate cytochromes with the correct wavelength and power of light it provides the cell with extra energy to grow, regenerate and heal. This bio-chemical reaction increases the production of Adenosine Triphosphate (ATP) which initiates vasodilation bring more oxygen rich blood to injured area.
High Power Lasers:Used to cut, coagulate and evaporate tissues. Often called surgical lasers because they can replace the scalpel of the surgeon. i.e. CO2 laserLow Level Lasers:Used for the stimulation of cell function. Their biological effect is not thermal, as is the case with surgical lasers. i.e. LED laser
Based on Various Settings: High Power Laser Actions ◦ Vaporization ◦ Hemostasis ◦ Decontamination Low Level Laser Therapy ◦ Biostimulation ◦ Modulation of Pain
Vaporization = Cutting◦ The diode laser’s wavelength is absorbed by pigmented tissues and cellular structures resulting in an incision similar to a surgical blade◦ Less thermal damage than other Surgical lasers! CO2 laser works by boiling water in tissues and rupturing cell membranes
CO2 Laser works by thermal action, therefore,some thermal damage is inevitable!
Less thermal damage results in less inflammation,and therefore, less swelling and pain
The diode laser’s wavelength is absorbed by hemoglobin Surrounding tissue collagen contraction results in the restriction of blood vessels in the targeted area
Active Bleeding Greatly Reduced on Treated Half
OPTIONS:“Cut & Sew”HemorrhageDifficult in small mouthElectrosurgeryPost-op swellingCO2 LaserRisk of charring or lasing pharynxDiode Laser ?
•Zero bleeding•Limited charring in portionused as “cutting”•Portion used as “pre-coag”followed by blade worked well•No dyspnea during recovery•Eating baby food in 18 hours
Also Known As ◦ Biostimulation ◦ Photobiomodulation ◦ “Cold Laser” therapy ◦ 3LT Because… The mechanism is photochemical rather than thermal
Light is absorbed by mitochondria in cells Stimulation of cellular ATP production and up-regulation of nitric oxide Secretion of growth factors, activation of enzymes and other secondary messengers ◦ Enhanced cell proliferation and differentiation
Increased neovascularization and temporary vasodilation “Photomodulation of Blood”– new term in medicine ◦ Enhanced leukocyte (WBC) infiltration ◦ Increased macrophage activity
Increased proliferation of cells ◦ Fibroblasts ◦ Endothelial cells ◦ Keratinocytes Shown to be true of hypoxic or stressed cells Healthy cells show little or no response
•Base of skull on right to caudal scapula•E. Coli was cultured from the wound•Littermates also affected
Immediately Post-OpTreated only caudal half of incision with diode laser following typical debridement
Day 4 post-op-Caudal (treated) half shows epithelialization
Day 4 post op-Cranial (non-treated) half has more scabbing and inflammation, no epithelialized areas Following day 4, the entire the wound was treated with the Pilot Diode Laser
At 15 days post-op, the entire wound was nicelyhealed with an atypically large amount of new hair growth.
Infectious dermatitis inthis frog was non-responsive to antibioticbaths and topicaltreatment.The prognosis wasterminally poor.
When laser therapy was introduced, antimicrobial treatment was discontinued. Diode laser therapy was applied at 2.0 watts for 2 seconds, twi ce weekly for four weeks. Leg after 2 Weeks of Diode Laser Therapy
Leg following 4 weeks of Diode Laser Therapy
Treated with Diode Laser at 2.0 watts for 2 minutes Every Other Day for 2 Weeks
No scabbing of the wound was ever noted The owl was released into the suburban wild at 2 weeks
In General Increases release of endorphins Increases serotonin Resolution of inflammation at least equivalent to NSAIDs Suppression of nociceptor action ◦ Inhibits nerve conduction in small and medium diameter peripheral nerves
Joint Pain Specifically Joint capsule and synovial membrane stimulation result in increased intra-articular circulation and ◦ healthier synovial fluid is generated ◦ Chondroblastic cellular formation is accelerated
Suppression of nociceptor action ◦ Localized treatment ◦ Inhibits nerve conduction in small and medium diameter peripheral nerves Induces neural blockade reducing central nerve sensitisation (pain memory) ◦ Spine and trigger point treatment