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Light
Amplification by
Stimulated
Emission of
Radiation
 http://spaceplace.nasa.gov/en/kids/laser/index.shtml
   Gas laser (CO2-welding, surgery)
        Excimer UV laser (LASIK)

   Solid-State laser
         Semiconductor
                (Telecom, Optical Storage, Laser Pointers)
         Fiber Hosted
                (the PILOT Diode Laser)
   Others--
    ◦ Chemical Laser,
    ◦ Photonic Crystal Laser,
    ◦ Dye Laser,
    ◦ Free Electron Laser, etc.
High Power Lasers and Low Level
              Lasers
High Power Lasers:
Used to cut, coagulate and evaporate tissues.
   Often called surgical lasers because they can
   replace the scalpel of the surgeon.
      i.e. CO2 laser

Low Level Lasers:
Used for the stimulation of cell function.
 Their biological effect is not thermal, as is the
 case with surgical lasers.
     i.e. LED laser
Based on Various Settings:

   High Power Laser Actions
          ◦ Vaporization
           ◦ Hemostasis
        ◦ Decontamination

   Low Level Laser Therapy
         ◦ Biostimulation
       ◦ Modulation of Pain
Vaporization = Cutting

◦ The diode laser’s wavelength is absorbed
  by pigmented tissues and cellular
  structures resulting in an incision similar
  to a surgical blade


◦ Less thermal damage than other Surgical lasers!
   CO2 laser works by boiling water in tissues
    and rupturing cell membranes
CO2 Laser works by thermal
        action, therefore,
some thermal damage is inevitable!
Less thermal damage results in less
           inflammation,
and therefore, less swelling and pain
   The diode laser’s wavelength is
    absorbed by hemoglobin

   Surrounding tissue collagen contraction
    results in the restriction of blood
    vessels in the targeted area
Active Bleeding Greatly Reduced on Treated Half
OPTIONS:

“Cut & Sew”
Hemorrhage
Difficult in small mouth

Electrosurgery
Post-op swelling

CO2 Laser
Risk of charring or lasing pharynx

Diode Laser ?
•Zero bleeding

•Limited charring in portion
used as “cutting”

•Portion used as “pre-coag”
followed by blade worked well

•No dyspnea during recovery

•Eating baby food in 18 hours
Treatment with Diode Laser
Simple, Fast Extraction Site Closure
   Also Known As
    ◦ Biostimulation
    ◦ Photobiomodulation
    ◦ “Cold Laser” therapy
    ◦ 3LT

                            Because…
                     The mechanism is
                  photochemical rather
                         than thermal
Light is absorbed by mitochondria in cells

   Stimulation of cellular ATP production
    and up-regulation of nitric oxide

   Secretion of growth factors, activation
    of enzymes and other secondary
    messengers
    ◦ Enhanced cell proliferation and
      differentiation
   Increased neovascularization and
    temporary vasodilation

   “Photomodulation of Blood”– new
    term in medicine
    ◦ Enhanced leukocyte (WBC)
      infiltration
    ◦ Increased macrophage activity
   Increased proliferation of cells
    ◦ Fibroblasts
    ◦ Endothelial cells
    ◦ Keratinocytes

   Shown to be true of hypoxic or
    stressed cells
   Healthy cells show little or no
    response
   Rapid Regeneration of:
    ◦   Skin
    ◦   Muscle
    ◦   Tendon
    ◦   Ligament
    ◦   Bone
    ◦   Nerves
24 Hours– no “red line”
  Gingivitis Resolved
Chronic Scalp Wound
  Following Trauma
Minimal healing over 1st month
-Duoderm Paste used
Lesion size after 1 month– outlined in red




Lesion size 24 hours later, following treatment with the Pilot
               Diode Laser- outlined in green
   Lesion-- 7 days, four treatments later
•Base of skull on right to caudal scapula
•E. Coli was cultured from the wound
•Littermates also affected
   Immediately Post-Op




Treated only caudal half of incision with diode laser following
                    typical debridement
Day 4 post-op-
Caudal (treated) half shows epithelialization
Day 4 post op-
Cranial (non-treated) half has more scabbing and
      inflammation, no epithelialized areas




  Following day 4, the entire the wound was treated with
                   the Pilot Diode Laser
At 15 days post-op, the entire wound was nicely
healed with an atypically large amount of new hair
                     growth.
Infectious dermatitis in
this frog was non-
responsive to antibiotic
baths and topical
treatment.

The prognosis was
terminally poor.
When laser therapy was
      introduced, antimicrobial treatment
              was discontinued.

   Diode laser
    therapy was
    applied at
    2.0 watts for
    2
    seconds, twi
    ce weekly
    for four
    weeks.
              Leg after 2 Weeks of Diode Laser Therapy
   Leg following 4 weeks of Diode Laser Therapy
   Complete Degloving Injury of Left Humerus
Treated with Diode Laser at 2.0 watts for 2
   minutes Every Other Day for 2 Weeks
No scabbing of the wound was ever noted




   The owl was released into the suburban wild at 2 weeks
In General
 Increases release of endorphins
 Increases serotonin
 Resolution of inflammation at least
  equivalent to NSAIDs
 Suppression of nociceptor action
  ◦ Inhibits nerve conduction in small and
    medium diameter peripheral nerves
Joint Pain Specifically
 Joint capsule and synovial membrane stimulation
  result in increased intra-articular circulation and
  ◦ healthier synovial fluid is generated
  ◦ Chondroblastic cellular formation is accelerated
    Suppression of nociceptor action
    ◦ Localized treatment
    ◦ Inhibits nerve conduction in small and medium
      diameter peripheral nerves

   Induces neural blockade reducing central nerve
    sensitisation (pain memory)
    ◦ Spine and trigger point treatment
There are > 50 positive Double Blind studies that
show clear evidence that Low Level Laser Therapy
(LLLT) is highly effective for the following conditions:
      chronic pain      acne, eczema         migraines
     acute              inflammatory
      (traumatic)         skin conditions
      pain               wounds and           sinusitis, tonsil
     tendonitis          burns                 litis
     carpal tunnel      non-healing          TMJ disorders
      syndrome            ulcers
     tennis/golfer      rheumatoid           Minere’s
      elbow               arthritis             disease
                         fibromyalgia         Tinnitis
                         lymph edema          vertigo
                         osteoarthritis

                                       http://www.drz.org/asp/cp/laser2.asp
   Cosmetic Uses
    ◦ Hair Re-growth

    ◦ Dental bleaching

    ◦ Non-surgical face lift and wrinkle correction and
      body contouring

    ◦ Non-surgical liposuction

    ◦ Laser enhanced breast augmentation
   Back Pain
   Bowed tendons
   Navicular disease
   Bucked shins
   Laminitis
   Cellulitis
   Joint Pain
   Suspensory ligament desmitis
De-gloving injuries
Chronic Otitis
Externa
Gingivitis/Perio
Tooth abscesses
Bite wounds
Hot Spots
Folliculitis
Pododermatitis
Lick Granuloma
Anal Gland abscesses
Rhinitis
Safety features
Patented fiber
management system               9 watt maximum

                                 Bright and easy to
                                 read display

Easy to use                       Programmable
handpiece and tips

                     Portable – light weight
   Variable 0.1 - 9 Watts
   400 micron fiber
   Continuous or pulse mode
   Portable – 5.5 lbs
   Unique/patented fiber management
   20 ft. of optical fiber
   Easy and intuitive to use
   Wireless foot pedal
   Aiming beam
   Disposable tips
The patented fiber
management system
goes where you want it.

The handpiece feels
and acts like a scalpel.
Minimal invasion into
surgical area. Fiber will
extend out to 20 ft.
Easy to use.
Straight or curved.
This essential feature aids
the surgeon in visualizing
exactly where the laser will
ablate and incise
tissue, before laser energy
is delivered.
.1 - 9 Watts of power.
Delicate enough for
biostimulation while
powerful enough for
daily surgery.
Laser fiber easily inserts
                       through laser port




Works with any scope
procedure…unlike CO2
Procedures

Pre-coagulation Followed by Steel Blade

                    Photo-contraction causing Hemostasis


                                      Controlled Bleeding
Procedures




                Bleeding            No Bleeding




             Photo taken within 5 seconds of incision
Procedures
Procedures

             Induce perianesthesia with
             laser, excise mass with
             scissors, coagulate and vaporize lesion
             to char 5 days/week
Procedures
Procedures


             Scalpel-like cutting with No bleeding
Procedures
Procedures




             Apex Decontamination
Procedures
Procedures
Pilot Laser in Veterinary Medicine - CAO Group

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Pilot Laser in Veterinary Medicine - CAO Group

  • 1.
  • 2. Light Amplification by Stimulated Emission of Radiation http://spaceplace.nasa.gov/en/kids/laser/index.shtml
  • 3. Gas laser (CO2-welding, surgery) Excimer UV laser (LASIK)  Solid-State laser Semiconductor (Telecom, Optical Storage, Laser Pointers) Fiber Hosted (the PILOT Diode Laser)  Others-- ◦ Chemical Laser, ◦ Photonic Crystal Laser, ◦ Dye Laser, ◦ Free Electron Laser, etc.
  • 4. High Power Lasers and Low Level Lasers
  • 5. High Power Lasers: Used to cut, coagulate and evaporate tissues. Often called surgical lasers because they can replace the scalpel of the surgeon. i.e. CO2 laser Low Level Lasers: Used for the stimulation of cell function. Their biological effect is not thermal, as is the case with surgical lasers. i.e. LED laser
  • 6. Based on Various Settings:  High Power Laser Actions ◦ Vaporization ◦ Hemostasis ◦ Decontamination  Low Level Laser Therapy ◦ Biostimulation ◦ Modulation of Pain
  • 7. Vaporization = Cutting ◦ The diode laser’s wavelength is absorbed by pigmented tissues and cellular structures resulting in an incision similar to a surgical blade ◦ Less thermal damage than other Surgical lasers!  CO2 laser works by boiling water in tissues and rupturing cell membranes
  • 8. CO2 Laser works by thermal action, therefore, some thermal damage is inevitable!
  • 9. Less thermal damage results in less inflammation, and therefore, less swelling and pain
  • 10. The diode laser’s wavelength is absorbed by hemoglobin  Surrounding tissue collagen contraction results in the restriction of blood vessels in the targeted area
  • 11. Active Bleeding Greatly Reduced on Treated Half
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17. OPTIONS: “Cut & Sew” Hemorrhage Difficult in small mouth Electrosurgery Post-op swelling CO2 Laser Risk of charring or lasing pharynx Diode Laser ?
  • 18. •Zero bleeding •Limited charring in portion used as “cutting” •Portion used as “pre-coag” followed by blade worked well •No dyspnea during recovery •Eating baby food in 18 hours
  • 19.
  • 21. Simple, Fast Extraction Site Closure
  • 22. Also Known As ◦ Biostimulation ◦ Photobiomodulation ◦ “Cold Laser” therapy ◦ 3LT Because… The mechanism is photochemical rather than thermal
  • 23. Light is absorbed by mitochondria in cells  Stimulation of cellular ATP production and up-regulation of nitric oxide  Secretion of growth factors, activation of enzymes and other secondary messengers ◦ Enhanced cell proliferation and differentiation
  • 24. Increased neovascularization and temporary vasodilation  “Photomodulation of Blood”– new term in medicine ◦ Enhanced leukocyte (WBC) infiltration ◦ Increased macrophage activity
  • 25. Increased proliferation of cells ◦ Fibroblasts ◦ Endothelial cells ◦ Keratinocytes  Shown to be true of hypoxic or stressed cells  Healthy cells show little or no response
  • 26. Rapid Regeneration of: ◦ Skin ◦ Muscle ◦ Tendon ◦ Ligament ◦ Bone ◦ Nerves
  • 27.
  • 28. 24 Hours– no “red line” Gingivitis Resolved
  • 29. Chronic Scalp Wound Following Trauma Minimal healing over 1st month -Duoderm Paste used
  • 30. Lesion size after 1 month– outlined in red Lesion size 24 hours later, following treatment with the Pilot Diode Laser- outlined in green
  • 31. Lesion-- 7 days, four treatments later
  • 32. •Base of skull on right to caudal scapula •E. Coli was cultured from the wound •Littermates also affected
  • 33. Immediately Post-Op Treated only caudal half of incision with diode laser following typical debridement
  • 34. Day 4 post-op- Caudal (treated) half shows epithelialization
  • 35. Day 4 post op- Cranial (non-treated) half has more scabbing and inflammation, no epithelialized areas Following day 4, the entire the wound was treated with the Pilot Diode Laser
  • 36. At 15 days post-op, the entire wound was nicely healed with an atypically large amount of new hair growth.
  • 37.
  • 38. Infectious dermatitis in this frog was non- responsive to antibiotic baths and topical treatment. The prognosis was terminally poor.
  • 39. When laser therapy was introduced, antimicrobial treatment was discontinued.  Diode laser therapy was applied at 2.0 watts for 2 seconds, twi ce weekly for four weeks. Leg after 2 Weeks of Diode Laser Therapy
  • 40. Leg following 4 weeks of Diode Laser Therapy
  • 41. Complete Degloving Injury of Left Humerus
  • 42. Treated with Diode Laser at 2.0 watts for 2 minutes Every Other Day for 2 Weeks
  • 43. No scabbing of the wound was ever noted The owl was released into the suburban wild at 2 weeks
  • 44. In General  Increases release of endorphins  Increases serotonin  Resolution of inflammation at least equivalent to NSAIDs  Suppression of nociceptor action ◦ Inhibits nerve conduction in small and medium diameter peripheral nerves
  • 45. Joint Pain Specifically  Joint capsule and synovial membrane stimulation result in increased intra-articular circulation and ◦ healthier synovial fluid is generated ◦ Chondroblastic cellular formation is accelerated
  • 46. Suppression of nociceptor action ◦ Localized treatment ◦ Inhibits nerve conduction in small and medium diameter peripheral nerves  Induces neural blockade reducing central nerve sensitisation (pain memory) ◦ Spine and trigger point treatment
  • 47. There are > 50 positive Double Blind studies that show clear evidence that Low Level Laser Therapy (LLLT) is highly effective for the following conditions:  chronic pain  acne, eczema  migraines  acute  inflammatory (traumatic) skin conditions pain  wounds and  sinusitis, tonsil  tendonitis burns litis  carpal tunnel  non-healing  TMJ disorders syndrome ulcers  tennis/golfer  rheumatoid  Minere’s elbow arthritis disease  fibromyalgia  Tinnitis  lymph edema  vertigo  osteoarthritis http://www.drz.org/asp/cp/laser2.asp
  • 48. Cosmetic Uses ◦ Hair Re-growth ◦ Dental bleaching ◦ Non-surgical face lift and wrinkle correction and body contouring ◦ Non-surgical liposuction ◦ Laser enhanced breast augmentation
  • 49.
  • 50. Back Pain  Bowed tendons  Navicular disease  Bucked shins  Laminitis  Cellulitis  Joint Pain  Suspensory ligament desmitis
  • 51. De-gloving injuries Chronic Otitis Externa Gingivitis/Perio Tooth abscesses Bite wounds Hot Spots Folliculitis Pododermatitis Lick Granuloma Anal Gland abscesses Rhinitis
  • 52.
  • 53. Safety features Patented fiber management system 9 watt maximum Bright and easy to read display Easy to use Programmable handpiece and tips Portable – light weight
  • 54. Variable 0.1 - 9 Watts  400 micron fiber  Continuous or pulse mode  Portable – 5.5 lbs  Unique/patented fiber management  20 ft. of optical fiber  Easy and intuitive to use  Wireless foot pedal  Aiming beam  Disposable tips
  • 55. The patented fiber management system goes where you want it. The handpiece feels and acts like a scalpel.
  • 56. Minimal invasion into surgical area. Fiber will extend out to 20 ft.
  • 57. Easy to use. Straight or curved.
  • 58. This essential feature aids the surgeon in visualizing exactly where the laser will ablate and incise tissue, before laser energy is delivered.
  • 59. .1 - 9 Watts of power. Delicate enough for biostimulation while powerful enough for daily surgery.
  • 60. Laser fiber easily inserts through laser port Works with any scope procedure…unlike CO2
  • 61. Procedures Pre-coagulation Followed by Steel Blade Photo-contraction causing Hemostasis Controlled Bleeding
  • 62. Procedures Bleeding No Bleeding Photo taken within 5 seconds of incision
  • 64. Procedures Induce perianesthesia with laser, excise mass with scissors, coagulate and vaporize lesion to char 5 days/week
  • 66. Procedures Scalpel-like cutting with No bleeding
  • 68. Procedures Apex Decontamination

Editor's Notes

  1. The exact mechanism is still being explored and debated
  2. These chemicals are located in energy compartments in the cell called mitochondria.  When you stimulate cytochromes with the correct wavelength and power of light it provides the cell with extra energy to grow, regenerate and heal. This bio-chemical reaction increases the production of Adenosine Triphosphate (ATP) which initiates vasodilation bring more oxygen rich blood to injured area.