what is Alzheimer disease

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Microbiology

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Food hygiene is more than cleanliness ...... Protecting food from risk of contamination, including harmful bacteria, poison and other foreign bodies. Preventing any bacteria present multiplying to an extent which would result in the illness of consumers or the early spoilage of the food. Destroying any harmful bacteria in the food by thorough cooking or processing. Discarding unfit or contaminated food.

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T-Cell Activation • Concept of immune response • T cell-mediated immune response • B cell-mediated immune response I. Concept of immune response • A collective and coordinated response to the introduction of foreign substances in an individual mediated by the cells and molecules in the immune system. II. T cell-mediated immune response • Cell-mediated immunity is the arm of the adaptive immune response whose role is to combat infection of intracellular pathogens, such as intracellular bacteria (mycobacteria, listeria monocytogens), viruses, protozoa, etc.

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Major Histocompatibility Complex MHC: • Major Histocompatibility Complex – Cluster of genes found in all mammals – Its products play role in discriminating self/non-self – Participant in both humoral and cell-mediated immunity • MHC Act As Antigen Presenting Structures • In Human MHC Is Found On Chromosome 6 – Referred to as HLA complex • In Mice MHC Is Found On Chromosome 17 – Referred to as H-2 complex • Genes Of MHC Organized In 3 Classes – Class I MHC genes • Glycoproteins expressed on all nucleated cells • Major function to present processed Ags to TC – Class II MHC genes • Glycoproteins expressed on macrophages, B-cells, DCs • Major function to present processed Ags to TH – Class III MHC genes • Products that include secreted proteins that have immune functions. Ex. Complement system, inflammatory molecules

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Antigen Processing and Presentation MID Antigens and “foreignness” • Antigens (or, more properly, immunogens) have a series of features which confer immunogenicity. • One of these features is “foreignness.” • So, we can infer that – most often – antigens – ultimately – originate externally. • (There are exceptions, of course. Some cells become transformed by disease [e. g., cancer] or by aging. In such instances, the antigens have an internal origin.)

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Difference between In-Situ and Ex-Situ conservation Conservation of biodiversity and genetic resources helps protect, maintain and recover endangered animal and plant species. There are mainly two strategies for the conservation of wildlife: In-situ conservation and Ex-situ conservation. Although, both the strategies aim to maintain and recover endangered species, they are different from each other. Let us see how they differ from each other!

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Evolution Of Bacteria Bacteria have existed from very early in the history of life on Earth. Bacteria fossils discovered in rocks date from at least the Devonian Period (419.2 million to 358.9 million years ago), and there are convincing arguments that bacteria have been present since early Precambrian time, about 3.5 billion years ago. Bacteria were widespread on Earth at least since the latter part of the Paleoproterozoic, roughly 1.8 billion years ago, when oxygen appeared in the atmosphere as a result of the action of the cyanobacteria. Bacteria have thus had plenty of time to adapt to their environments and to have given rise to numerous descendant forms.

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Impact of Environment on Loss of Genetic Diversity and Speciation Genetic variation describes naturally occurring genetic differences among individuals of the same species. This variation permits flexibility and survival of a population in the face of changing environmental circumstances. Consequently, genetic variation is often considered an advantage, as it is a form of preparation for the unexpected. But how does genetic variation increase or decrease? And what effect do fluctuations in genetic variation have on populations over time?

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GENE ENVIRONMENT INTERACTION Subtle differences in one person’s genes can cause them to respond differently to the same environmental exposure as another person. As a result, some people may develop a disease after being exposed to something in the environment while others may not. As scientists learn more about the connection between genes and the environment, they pursue new approaches for preventing and treating disease that consider individual genetic codes.

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How to store food in hot The Good News To maximize benefit of preservation, keep your food as fresh as possible for as long as possible. You can do this, even in the heat, by creating a “cooler” made from two basic terra cotta pots, one larger than the other. Put the smaller pot in the larger one, fill the gap with sand, and saturate the sand with water. Then cover it with a cloth. To add additional insulation from the heat, bury the pot up to its rim. The evaporation of moisture from the wet sand will cool the air around the food and help keep it fresh.

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What is IUPAC naming? In order to give compounds a name, certain rules must be followed. When naming organic compounds, the IUPAC (International Union of Pure and Applied Chemistry) nomenclature (naming scheme) is used. This is to give consistency to the names. It also enables every compound to have a unique name, which is not possible with the common names used (for example in industry). We will first look at some of the steps that need to be followed when naming a compound, and then try to apply these rules to some specific examples.

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