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1. Obesity And Type 2
Diabetes: What
You Need To Know weight-sense.com

2. • See, Obesityis not just a weight issue—- or an aesthetic
issue.It is a health risk, and it’s a well-established riskfactor
in the development ofdiabetes and cardiovascular disease.
• A common denominator between obesityand diabetes is
insulin resistance.
• I thinkof insulin resistance as the “pre-” pre-diabetes.
• Before there’s diabetes,there’s pre-diabetes, and before
pre-diabetes,there are signs of insulin resistance.
• See, Type 2 Diabetes is a progressivedisease, and ifwe
start to notice and treat the signs earlier before the disease
sets in we can be successful in preventingthe onset of Type
2 Diabetes and all of its known complications,such as heart
attack,stroke, dementia,and kidneyfailure.
Obesity stands as the primary risk
factor for Type 2 diabetes mellitus.

3. What is Insulin and Insulin
Resistance?
• Insulin resistance is when the body becomes less responsive to insulin.
• Insulin is the hormone released by the pancreas and helps control blood
glucose levels in the bloodstream. The body likes homeostasis and wants to
maintain a blood glucose range between 60-100 fasting and less than 200 two to
three hours after meals to stay healthy. Insulin is the hormone that tells the
muscle, liver, and adipose cells to use the glucose available in the bloodstream
after meals as an energy source.
• But in insulin resistance, the body’s cells stop responding to the insulin signal.
In essence, there’s so much glucose and insulin around in the bloodstream that
the cells stop noticing the signals and stop responding.

4. Pre-Diabetes and Metabolic
Syndrome
• Over time, this leads to higher and higher blood glucose levels. The higher blood
glucose levels are associated with other metabolic derangements, which can startto show
on labs as signs of pre-diabetes and signs of metabolic syndrome—- this includes:
• Increased Waist Circumference: >40 inches Men and > 35 inches Female
• High Blood Pressure : ≥130/ ≥85 mmHg
• Blood Glucose (Pre-Diabetes): ≥100 mg/dL
• Increased Triglycerides: ≥150 mg/dL
• HDL cholesterol: men <40 mg/dL (1.04mmol/L) and women<50 mg/dL (1.30 mmol/L)
• Clinically, this can startshowing up for patients as signs of PCOS (irregular menstrual
cycle, increased hair growth on the face, acne) or fatigue.

5. Type 2 Diabetes Diagnoses
• Type 2 Diabetes is diagnosed when the labs show (2) of the followinglevels:
• Randomblood glucose greater than 200 mg/dL
• Fastinggreater than orequal to 126 mg/dL
• Two-hourplasma glucose greater than 200 duringa 75-g oral glucose tolerance test
• HgA1c greater than orequal to 6.5
• Eventually,the pancreas,whose beta cells produce insulin,may“burn out”or stop beingable to
produce the hormone insulin altogether.This is what happens in the later stages of Type 2 Diabetes
when insulin is required.
• When we havean excessive amount oflarge glucose molecules in our bloodstream at dangerously
high levels, complicationsfrom Type 2 Diabetes can arise.These complications mayinclude heart
disease, dementia,kidneydisease, retina (vision)disease, and nerve damage.

6. Summary:
• Obesity is the number one risk factor for Type 2 diabetes, as it is closely linked to insulin resistance. Insulin
resistance occurs when the body becomes less responsive to insulin, leading to higher blood glucose levels. Pre-
diabetes and metabolic syndrome are often precursors to Type 2 diabetes, characterized by increased waist
circumference, high blood pressure, elevated blood glucose, and abnormal lipid levels. Lifestyle changes, such as
improving diet, increasing physical activity, and optimizing sleep, can help improve insulin resistance. Additionally,
weight loss of around 7% can significantly reduce the risk of pre-diabetes progressing to diabetes. Pharmacological
interventions, including anti-diabetes medications and anti-obesity medications, can also be effective in preventing
diabetes and improving health.
• That’s why it is good to have a doctor on your team who understands obesity and type 2 diabetes, can meet you
where you’re at, and can support you and care for you based on expert guidance and recommendations.
• Book an appointment with me today. Together, we can transform your health dreams into an achievable reality.