EFFECT OF CINNAMALDEHYDE FROM CINNAMON EXTRACT AS A NATURAL PRESERVATIVE ALTERNATIVE TO THE GROWTH OF Staphylococcus aureus BACTERIA

2. Cinnamomum
verum
Presented By: Sanam Rafaqat Ali
Hamdard Al – Majeed College Of Eastern Medicine

3. TABLE OF
CONTENTS Medicinal properties
Introduction
History of Cinnamon
As an Antibiotic Herb
Unani concept (Temperament)
Conclusion
Chemical constituents

4. Family name
Lauraceae
Latin name
Cinnamomum verum
English name
Cinnamon
Urdu name
Darr cheeni
Arabic name
karfa
INTRODUCTION

5. HISTORY OF CINNAMON
Egypt as early as 3000 BC
Old testament of the Bible
Phoenician
Kinnámōmon = sweet wood
Sri Lanka
CeylonIn 2006, 90% Cinnamon producedIndonesia, produces 40%
of Cinnamon

6. CHEMICAL CONSTITUESNTS
Cinnamaldehyde
Bark
Cinnamyl acetate
Flowers
Cinnamic acid
Fruit
Eugenol
Leaves
NUTRITIONAL VALUE
Carbohydrates
Protein
Calcium
Vitamin k
Fats
Iron

7. TRADITIONAL USES
Antioxidant
High cholesterol
Anti-inflammatory
Anti-cancer
Anti-diabetic
Anti-microbial

8. WHAT IS ANTIBIOTIC ??
Antibiotic is a naturally occurring semi synthetic & synthetic type
of agents that destroy or inhibit growth of micro-organism
Inhibition of
protein synthesis
Inhibition of nucleic
acid synthesis
Inhibition of cell
wall synthesis
Disruption of cell
membrane functions
Inhibit metabolism

10. Bark extracts, obtained with
different organic solvents, as
ethyl acetate, acetone and
methanol, work against
In the same year, ethanolic
extract of stem bark work
against,
• Methicillin resistance
streptococcus aureus (MRSA)
• It work as Bacteriostatic
(Minimum inhibitory
concentration), after 6 hours it
act as Bactericidal.
• Klebseilla pneumonia
• Pseudomonas aeruginosa
• Staphylococcus aureus
• Escherichia coli
• Enterobacter cloaceac
• Corynebacterium xerosis
• Streptococcus fecalis
RESEARCH ARTICLE
2011

11. Analysis with thin layer chromatography
(TLC) & gas coupled with mass
spectrometry (GC – MS) antibacterial
activity against all selected strains,
Resulting as most abundant constituents
are present
• Cinnamaldehyde (4.3%)
• Eugenol (0.32%)
2012
Cinnamon bark essential oil,
expressed as (Minimum inhibitory
concentration) against several
pathogenic bacterial strains
• Salmonella typhi
• Escherichia coli
• Staphylococcus aureus
• Pseudomonas fluorescens
• Bacillus licheniformis
RESEARCH ARTICLE
Fresh leaves essential oil
for dental plaque
formation & caries
developement
• Streptococcus mutans
• Lactobacillus acidophilus

12. 2013
Cinnamon work against (MDR)
Gram negative bacteria over
expressing active efflux pump,
which make bacteria resistant to
antibiotic treatment.
RESEARCH ARTICLE
• Escherichia coli
• Enterobacter aerogenes
• Pseudomonas aeruginosa
• Klebseilla pneumonia
• Enterobacter cloaceac

13. Hot 2 Dry 3
Temperament

14. COMPOUNDS

15. CORRIGENT (MUSLEH) TENEDIUM (BADAL)
Khameera -e-
Banafshah
Sandal Safaid Kholanjan Kabab Cheeni

16. The antibacterial effects of cinnamon and its active
constituents, published over the last five years. It has
shown that the antibacterial activity of cinnamon is due
to bioactive phytochemical such as cinnamaldehyde
and eugenol.