Liver transplant surgery is a procedure in which the defective liver of the patient is replaced by the healthy liver of another person who is also known as the donor. Rising Health Care provides the best medical services to patients searching for a top liver hospital in India.
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Liver Transplant in India.pdf
1. Liver Transplant in India
Liver transplant surgery is a procedure in which the defective liver of the patient is
replaced by the healthy liver of another person who is also known as the
donor. Rising Health Care provides the best medical services to patients searching for a
top liver hospital in India.
While going through the procedure of liver transplant in India there are many things
to be kept in mind like, not every donor can donate his or her organ because the
reports of the donor should match the reports of the receiver but the donor can be a
family member or the outsider that will not matter.
The most important thing to note is that this is the only organ that can grow itself
over time. So the donor, as well as the receiver, can live a healthy life with some part
of the healthy liver inside their body as it will grow with time. This is the main
reason that while liver transplant only a small portion of the donor liver is taken for
the receiver and not the complete organ.
2. Why do we need to undergo the liver transplant
surgery?
The liver is the most crucial part of the human body as it supports metabolism,
immunity, digestion, detoxification, and vitamin storage. We need a healthy liver to
live a healthy life. If at any time liver is found ill the patient is recommended to
undergo a liver transplant procedure.
There can be many reasons for liver failure and some of them are as follows:
1. Cirrhosis: This type of issue is majorly caused due to excessive intake of
alcohol. This is one of the most common reasons for the liver to be damaged. In
this condition, the healthy tissues of the liver are replaced by damaged tissues
so this affects the liver health badly.
2. Hepatic Necrosis: It is caused due to direct hepatotoxin and depends upon
the dosage rather than idiosyncratic. It affects the liver when the liver tissues
cease their functions.
3. Viral Hepatitis: In this type of Infection liver inflammation happens all across
the organ. Several different viruses cause hepatitis, including hepatitis A, B, C,
D, and E.
4. Metabolic Diseases: It is a kind of disease that includes Wilson’s disease,
hemochromatosis, familial amyloidotic polyneuropathy, Alpha-1-antitrypsin
deficiency, tyrosinemia, glycogen storage disease, and other related disorders
that change the chemical processing of the cells. It also affects the liver and a
person needs to undergo a liver transplant surgery.
5. Early-stage Liver Cancer: When the early stage liver cancer appears there is
unintentional weight loss, nausea and vomiting, general weakness and fatigue,
abdominal swelling, and jaundice and due to this eyes and skin colour turns
yellow. This type of tumour starts developing in the liver but this is the early
stage and can be cured by liver transplant surgery.
3. Major Symptoms of Liver Transplant
There are some of the major symptoms due to which a person should undergo a liver
transplant surgery that is as follows:
1. Jaundice
2. Gastrointestinal bleeding
3. Encephalopathy
4. Fluid retention
Requirement for the donor to donate the organ for
liver transplant surgery
Before undergoing a liver transplant surgery the donor need to be evaluated and
checked properly. There are certain criteria for a donor to donate his or her lungs to
the recipient.
1. Must be in good physical and mental health.
2. Must be between the ages of 18 and 60.
3. Must have a body mass index (BMI) that is less than 35.
4. Must have a compatible blood type with the recipient.
5. Must be free from the following: Significant organ diseases (i.e., heart disease,
kidney disease, etc.)
4. Criteria to Undergo A Liver Transplant
Liver transplantation is a complex procedure that is reserved for individuals with
severe liver disease or acute liver failure. There is a high demand for liver
transplant in India so that is why when you search for a liver transplant you will
get to know that there is the best liver transplant hospital in Delhi India. To
determine eligibility for a liver transplant, certain criteria are established. These
criteria include:
1. The severity of Liver Disease: Candidates must have advanced liver disease,
such as cirrhosis, that significantly impairs liver function. Diagnostic tests and
scoring systems help assess the severity of the condition.
2. Life-Threatening Condition: The patient’s condition should be life-
threatening, with a high risk of mortality without a transplant within a short
period.
3. Absence of Contraindications: Certain factors, such as active substance
abuse or severe heart or lung disease, may exclude a patient from receiving a
transplant.
4. Psychological and Social Evaluation: Candidates undergo an evaluation to
ensure they have a support system and can cope with the demands of post-
transplant care.
5. Lack of Suitable Alternative Treatment: Other medical and surgical
therapies should have been exhausted without success.
6. Expected Post-Transplant Compliance: Patients must demonstrate a
commitment to adhere to post-transplant care requirements.
These criteria help transplant centres determine the most appropriate candidates for
liver transplantation based on the available donor organs and the individual’s overall
health and prognosis. It is important to consult with a transplant specialist to
determine if a liver transplant is the best course of action for a particular patient.
Complications of Liver Transplant Surgery
Liver transplant surgery is a major procedure that can be accompanied by
various complications. While advancements in surgical techniques and post-
operative care have reduced the risks, complications can still occur. Some common
complications include:
1. Rejection: The body’s immune system may identify the transplanted liver as
foreign and attempt to attack it, leading to rejection. Immunosuppressive
medications are prescribed to prevent this.
2. Infection: Infections can occur due to the weakened immune system after
transplantation. Strict precautions are taken to minimize the risk of infections.
5. 3. Bleeding: Surgery involves major blood vessels, which can lead to bleeding.
Immediate medical attention is crucial to control bleeding.
4. Bile Duct Complications: Bile ducts can become narrowed or develop leaks,
requiring intervention through procedures like endoscopic stenting or surgical
revision.
5. Organ Failure: In some cases, the transplanted liver may not function
properly, leading to graft failure. In such cases, a re-transplantation may be
necessary.
6. Side Effects of Medications: Immunosuppressive medications used to
prevent rejection can have side effects, including increased susceptibility to
infections, kidney problems, and metabolic disorders.
Patients need to be aware of these potential complications and closely follow the
post-transplant care plan to minimize risks and ensure a successful recovery.
Regular monitoring and communication with the transplant team are crucial in
managing and addressing any complications that may arise.
Side-effects of anti-rejection medicine side effects
may cause:
After a liver transplant, one of the key components of post-transplant care is the use
of immunosuppressive medications. These medications are essential to prevent
rejection of the transplanted liver by suppressing the body’s immune system. While
they play a crucial role in the success of the transplant, it’s important to be aware of
their potential side effects. Here are some common side effects associated with anti-
rejection medications:
1. Increased Susceptibility to Infections: Immunosuppressive drugs weaken
the immune system, making individuals more susceptible to infections.
Common infections may include respiratory infections, urinary tract infections,
or viral infections.
2. Kidney Problems: Some anti-rejection medications can affect kidney
function. This may lead to conditions such as high blood pressure or kidney
damage. Regular monitoring of kidney function is necessary to detect any
abnormalities early.
3. Metabolic Disorders: Certain medications can cause metabolic changes in
the body, such as increased cholesterol or blood sugar levels. Regular
monitoring and appropriate management of these metabolic effects are crucial.
4. Bone Thinning: Long-term use of immunosuppressive drugs may contribute
to bone loss, leading to osteoporosis or increased risk of fractures. Adequate
calcium and vitamin D intake, along with regular exercise, can help mitigate this
risk.
6. 5. Gastrointestinal Issues: Some individuals may experience side effects such
as stomach upset, nausea, or diarrhoea due to the medications.
It’s important to note that not all individuals will experience these side effects, and
the severity may vary. Transplant teams closely monitor patients and adjust
medication dosages to find the right balance between preventing rejection and
minimizing side effects. Regular follow-up visits and open communication with the
transplant team are crucial in managing any side effects that may arise.
While the side effects of anti-rejection medications can be challenging, it’s essential
to weigh them against the benefits of a successful liver transplant. Close adherence
to medication schedules, maintaining a healthy lifestyle, and regular medical check-
ups can help mitigate the impact of these side effects and ensure the best possible
outcome for the transplant recipient.
Investigations and Tests required for patients and
donors before Liver Transplant.
Liver transplantation is a complex procedure that requires a thorough evaluation of
both the recipient (patient) and the potential living donor. This evaluation process
involves a series of investigations and tests to ensure the suitability of the transplant
and minimize risks. Here are some of the common investigations and tests
conducted:
1. Patient Evaluation: a. Medical History: A detailed medical history is taken to
assess the patient’s liver disease progression, previous treatments, and any
underlying conditions. b. Physical Examination: A comprehensive physical
examination helps identify any signs or symptoms related to liver disease. c.
Blood Tests: Various blood tests are conducted to assess liver function,
determine blood type, and check for viral infections like hepatitis B and C. d.
Imaging Studies: Imaging techniques like ultrasound, CT scan, or MRI are used
to evaluate liver structure, detect any abnormalities, and assess blood vessel
anatomy. e. Cardiac Evaluation: Cardiac assessment, including
electrocardiogram (ECG) and echocardiogram, helps determine the patient’s
heart health before surgery. f. Pulmonary Function Tests: Lung function tests
assess the patient’s respiratory capacity and detect any underlying lung disease.
2. Donor Evaluation: a. Blood Tests: Blood typing, cross-matching, and
antibody testing are performed to ensure compatibility between the donor and
recipient. b. Imaging Studies: Similar to the patient evaluation, imaging studies
help evaluate the donor’s liver structure and blood vessel anatomy. c. Liver
7. Biopsy: A biopsy may be performed to assess the health and quality of the donor
liver. d. Psychological Evaluation: Donors undergo psychological assessment to
ensure they fully understand the procedure and have the necessary support.
3. Additional Evaluations: a. Transplant Infectious Disease Evaluation:
Screening for infectious diseases, such as HIV and tuberculosis, is essential for
both patient and donor. b. Nutrition Assessment: A nutritionist evaluates the
patient’s nutritional status and provides guidance to optimize nutritional
support. c. Social Evaluation: Social workers assess the patient and donor’s
support system, including financial resources and availability of a caregiver
post-transplant.
These investigations and tests help the transplant team determine the eligibility of
both the patient and the donor, assess the risks, and plan the transplantation
procedure accordingly. The results guide the decision-making process and ensure
the best possible outcomes for both the recipient and the donor. It’s crucial for
patients and potential donors to actively participate in the evaluation process and
communicate openly with the transplant team.
Liver Transplant in India
Liver transplantation is a life-saving procedure for individuals with end-stage liver
disease. While the procedure can be expensive in many countries, India has emerged
as a popular destination for affordable liver transplants. The liver transplant cost
in India is significantly lower compared to Western countries, making it an
attractive option for patients seeking quality healthcare at a more affordable price.
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cost in delhi when it comes to liver transplant requirement. So for your reference
we bring to you a complete info on the liver transplant cost in india in rupees.
The average cost of a liver transplant in India can vary depending on several factors
such as the hospital, surgeon’s fees, type of transplant (cadaveric or living donor),
pre and post-operative care, diagnostic tests, and medications. On average, the cost
of a liver transplant in India can range from $60,000 to $80,000, which is
considerably lower compared to countries like the United States, where it can exceed
$500,000.
The lower cost of liver transplantation in India does not compromise the quality of
medical care. Indian hospitals and transplant centers are equipped with state-of-the-
art infrastructure, modern technology, and experienced medical professionals who
are skilled in performing liver transplant surgeries. Many transplant centers in India
8. have internationally recognized accreditations and follow stringent quality
standards.
Patients considering a liver transplant in India should thoroughly research and
choose reputed transplant centers with a successful track record and positive patient
testimonials. Consulting with a medical tourism facilitator or seeking guidance from
a healthcare professional can also help navigate the process and make informed
decisions.
Overall, India’s affordable liver transplant costs, coupled with high-quality medical
care, have made it a preferred destination for patients seeking a cost-effective
solution for their liver transplant needs.