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Dr. T. M. Fahad Nasif
Assistant Registrar,
Dept of Paediatrics
ICMH, Dhaka.
Date: 15/07/13
Name - B/O of Amena
Age -28 Hours
Weight -2.5kg.
Sex -Female.
Address -Bondor,Narayanganj
DOB - 14/06/13 at 1.00PM
DOA &DOE - 15/06/13 at 5.00PM
Yellowish coloration of whole body for last
10 hours
According to the statement of patient’s
attendant the newborn was delivered at
39wks of gestation at home 28hours back by
NVD. Baby cried just after delivery. Mother
noticed yellowish coloration of whole body
for last 10 hours starting from face and which
was increasing with time. There is no history
of bluish colouration, poor feeding, fever,
convulsion or meconium stained liquor. With
this complain the baby got admitted to ICMH
for better management.
Antenatal-
 Mother 30years,non-diabetic,non-
hypertensive.
 No history of fever with rash.
 No previous history of heart or lung disease.
 She was on irregular ante-natal check-up
(only 2 visits at 28 and 36 weeks).
 Blood group- O-negative
 Antibody titre- not done
 She had no history of PROM, foul smelling per
veginal discharge or abdominal pain
 No history of drug ingestion except multi
vitamin
Natal History-
 The baby was born by NVD at home at 39 wks
of gestational age.
 The baby cried just after birth.
 APGAR score- Not known.
 Baby was active, sucking well.
Postnatal history-
 Passed urine 1 hour and stool 6hours after
birth.
 Noticed yellowish coloration of face and body
at 18-20hours of age
Birth History cont’d….
 Exclusive breast feeding.
 No prelacteal feeding was given.
 3rd issue of non consanguineous
parents.
 Previous 2 siblings are in good health.
They have no history of neonatal
jaundice.
 Father’s blood group- O(+ve)
Family History
Father - Shopkeeper
Mother - house wife
housing - Tinshed house
Drinks tube well water.
Uses sanitary latrine.
Appearance- Sick-looking, Icteric, pale.
Colour- Yellowish
Anaemia- Moderate.
Jaundice- present upto thigh.
Cyanosis- absent
Temp- 99˚F.
RR- 42/Min.
HR- 140/Min.
Fontanel- Open & normal.
Skin survey- Normal, no bleeding spot.
Scalp-
Face- Normal.
Eyes-
Neck-
Genitalia- Normal.
Extremities- Normal.
Spine- Normal.
Umbilicus- Healthy.
Tone- Normal.
Primitive reflexes- Moderate.
Anthropometry-
 Weight-2.5kg(In between 10th to 50th
centile)
 Height-46.7cm(50th centile)
 OFC-34cm(In between 50th to 90th centile)
 Mouth & Oral cavity-normal.
 Abdomen proper
Inspection-
Shape-normal.
Umbilicus centrally placed & healthy.
Palpation-
Liver & spleen- just palpable.
Auscultation-
Bowel Sound- present.
 Inspection:
R/R: 42/min
No chest Indrawing.
Movement of chest: Bilaterally
symmetrical.
 Palpation:
Trachea: Centrally placed.
Apex beat: Lt 5th intercostal space just
medial to midclavicular line.
 Auscultation:
Air entry good & equal in both side. Breath
sound vesicular in both lung field.
Inspection-
Precordium- Normal.
HR-140/Min.
No visible pulsation.
Palpation-
Apex beat in left 5th ICS medial to MCL.
Normal in character.
Auscultation-
S1 & S2 audible in all cardiac area.
A soft systolic murmur present
B/O Amena, 28hours old female child, 3rd
issue of non consanguinous parents, weight
2.5kg delivered at home by NVD at 39wks of
gestation was admitted to ICMH with the
complaint of yellowish coloration of whole
body which started from face since18-20
hours of life. The baby cried just after birth.
There is no history of bluish coloration, poor
feeding, fever or convulsion. Mother didn’t
take regular ANC & had no history of PROM,
prolonged labour or obstructed labour.
Mother’s blood group O(-ve), antibody titre
not done. Father’s blood group O(+ve).
Previous 2 siblings were normal and no
history of neonatal jaundice. On examination,
baby is ill-looking, pale, icteric upto the
thigh, Vital signs are normal, Frontanel-
normal, normotonic, primitive reflexes-
moderate. Liver and spleen just palpable.
Other system reveals no abnormalities.
Term AGA with Neonatal Jaundice
(Most probably Rh incompatibility )
 Minor blood group incompatibility
 G6PD deficiency
Blood group: O positive
Serum Billirubin(At 46 HOL)
Total: 20.9mg/dl
Direct:3.2mg/dl
Indirect:17.7mg/dl
Hb: 9.6 gm/dl
TC: 11,530/cumm
DC: N-69%, L-26%,M-3%,B-2%
Platelets count-2,57000/cumm
PBF- Features of hemolysis.
 Coomb’s Test (direct): Negative
 CRP: <6mg/dl
 RBS- 5.7mmol/L
 Blood culture-No growth
Neonatal jaundice due to
Rh incompatibility
 Exclusive breast feeding
 Extensive Phototherapy (double blue)
 Inf.10% Baby saline(80ml/kg for 24hr).
 Antibiotic-Inj.Ampicillin(100mg/kg/day) &
Inj.Gentamicin(5mg/kg/day)
Umbilical catheterization done
 Plan-
Double volume exchange blood transfusion
Requisition given for O(-ve) blood
 Baby develope convulsion
 Temp 1000F
 Inj.Phenobarbitone(20mg/kg loading &
5mg/kg/day maintenance)
 Antibiotic changed-
Inj.Ceftazidime(150mg/kg/day)
Inj.Amikacin(15mg/kg/day)
Inj.Metronidazole(1.5ml/kg/dose)
On day 3 (59 HOL)
Hb- 6.9g/dl
Serum Billirubin-
Total- 22.0mg/dl
Direct-2.9mg/dl
Indirect-19.0mg/dl
Serum Electrolytes
Na-140mmol/L
K-3.6mmol/l
Cl-96.9mmol/l
Serum Calcium-8.9mg/dl
Serum creatinine-0.9mg/dl
 Baby develope high grade fever
 Temp 1040F
 Antibiotic Changed
Inj. Meropenam(40mg/kg/dose)
On day 4 (80HOL)
 Hb- 9.0gm/dl
 Serum Billirubin-
Total-7.8mg/dl
Direct-0.8mg/dl
Indirect-7.0mg/dl
 Serum Electrolytes-
Na-140.2mg/dl,
K-3.8mg/dl,
Cl-96.9mg/dl
 Serum calcium-8.2mg/dl
 Serum creatinine-0.8mg/dl
Day C/C Temp Anaemia Jaundice Reflexes Manage
ment
Day5 Fever 102° F Pale Upto
abdomen
Moderate Continue
photo
therapy
Day6 Fever 100° F Pale Face Good Transfusi
on O-ve
blood
Day7 None 99°F Absent Face Good Medicati
on
as before
Baby was discharged on day-9…
Well alert
Colour-pink.
RR-42/min.
HR-130/min.
Mildly icteric.
Hypertonic
Sucking breast milk properly
Medication-Tab.phenobarbitone(5mg/kg BD)
Advice-Follow up after 7days
Immunization.
Exclusive breast feeding.
 Baby active
 Tone normal
 Anaemia- absent
 Jaundice- absent
 Reflexes good
Rh incom

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Rh incom

  • 1. Dr. T. M. Fahad Nasif Assistant Registrar, Dept of Paediatrics ICMH, Dhaka. Date: 15/07/13
  • 2. Name - B/O of Amena Age -28 Hours Weight -2.5kg. Sex -Female. Address -Bondor,Narayanganj DOB - 14/06/13 at 1.00PM DOA &DOE - 15/06/13 at 5.00PM
  • 3. Yellowish coloration of whole body for last 10 hours
  • 4. According to the statement of patient’s attendant the newborn was delivered at 39wks of gestation at home 28hours back by NVD. Baby cried just after delivery. Mother noticed yellowish coloration of whole body for last 10 hours starting from face and which was increasing with time. There is no history of bluish colouration, poor feeding, fever, convulsion or meconium stained liquor. With this complain the baby got admitted to ICMH for better management.
  • 5. Antenatal-  Mother 30years,non-diabetic,non- hypertensive.  No history of fever with rash.  No previous history of heart or lung disease.  She was on irregular ante-natal check-up (only 2 visits at 28 and 36 weeks).  Blood group- O-negative  Antibody titre- not done  She had no history of PROM, foul smelling per veginal discharge or abdominal pain  No history of drug ingestion except multi vitamin
  • 6. Natal History-  The baby was born by NVD at home at 39 wks of gestational age.  The baby cried just after birth.  APGAR score- Not known.  Baby was active, sucking well. Postnatal history-  Passed urine 1 hour and stool 6hours after birth.  Noticed yellowish coloration of face and body at 18-20hours of age Birth History cont’d….
  • 7.  Exclusive breast feeding.  No prelacteal feeding was given.
  • 8.  3rd issue of non consanguineous parents.  Previous 2 siblings are in good health. They have no history of neonatal jaundice.  Father’s blood group- O(+ve) Family History
  • 9. Father - Shopkeeper Mother - house wife housing - Tinshed house Drinks tube well water. Uses sanitary latrine.
  • 10. Appearance- Sick-looking, Icteric, pale. Colour- Yellowish Anaemia- Moderate. Jaundice- present upto thigh. Cyanosis- absent Temp- 99˚F. RR- 42/Min. HR- 140/Min. Fontanel- Open & normal. Skin survey- Normal, no bleeding spot.
  • 11. Scalp- Face- Normal. Eyes- Neck- Genitalia- Normal. Extremities- Normal. Spine- Normal. Umbilicus- Healthy. Tone- Normal. Primitive reflexes- Moderate.
  • 12. Anthropometry-  Weight-2.5kg(In between 10th to 50th centile)  Height-46.7cm(50th centile)  OFC-34cm(In between 50th to 90th centile)
  • 13.  Mouth & Oral cavity-normal.  Abdomen proper Inspection- Shape-normal. Umbilicus centrally placed & healthy. Palpation- Liver & spleen- just palpable. Auscultation- Bowel Sound- present.
  • 14.  Inspection: R/R: 42/min No chest Indrawing. Movement of chest: Bilaterally symmetrical.  Palpation: Trachea: Centrally placed. Apex beat: Lt 5th intercostal space just medial to midclavicular line.  Auscultation: Air entry good & equal in both side. Breath sound vesicular in both lung field.
  • 15. Inspection- Precordium- Normal. HR-140/Min. No visible pulsation. Palpation- Apex beat in left 5th ICS medial to MCL. Normal in character. Auscultation- S1 & S2 audible in all cardiac area. A soft systolic murmur present
  • 16. B/O Amena, 28hours old female child, 3rd issue of non consanguinous parents, weight 2.5kg delivered at home by NVD at 39wks of gestation was admitted to ICMH with the complaint of yellowish coloration of whole body which started from face since18-20 hours of life. The baby cried just after birth. There is no history of bluish coloration, poor feeding, fever or convulsion. Mother didn’t take regular ANC & had no history of PROM, prolonged labour or obstructed labour.
  • 17. Mother’s blood group O(-ve), antibody titre not done. Father’s blood group O(+ve). Previous 2 siblings were normal and no history of neonatal jaundice. On examination, baby is ill-looking, pale, icteric upto the thigh, Vital signs are normal, Frontanel- normal, normotonic, primitive reflexes- moderate. Liver and spleen just palpable. Other system reveals no abnormalities.
  • 18. Term AGA with Neonatal Jaundice (Most probably Rh incompatibility )
  • 19.  Minor blood group incompatibility  G6PD deficiency
  • 20. Blood group: O positive Serum Billirubin(At 46 HOL) Total: 20.9mg/dl Direct:3.2mg/dl Indirect:17.7mg/dl Hb: 9.6 gm/dl TC: 11,530/cumm DC: N-69%, L-26%,M-3%,B-2% Platelets count-2,57000/cumm PBF- Features of hemolysis.
  • 21.  Coomb’s Test (direct): Negative  CRP: <6mg/dl  RBS- 5.7mmol/L  Blood culture-No growth
  • 22. Neonatal jaundice due to Rh incompatibility
  • 23.  Exclusive breast feeding  Extensive Phototherapy (double blue)  Inf.10% Baby saline(80ml/kg for 24hr).  Antibiotic-Inj.Ampicillin(100mg/kg/day) & Inj.Gentamicin(5mg/kg/day) Umbilical catheterization done  Plan- Double volume exchange blood transfusion Requisition given for O(-ve) blood
  • 24.  Baby develope convulsion  Temp 1000F  Inj.Phenobarbitone(20mg/kg loading & 5mg/kg/day maintenance)  Antibiotic changed- Inj.Ceftazidime(150mg/kg/day) Inj.Amikacin(15mg/kg/day) Inj.Metronidazole(1.5ml/kg/dose)
  • 25. On day 3 (59 HOL)
  • 26.
  • 27. Hb- 6.9g/dl Serum Billirubin- Total- 22.0mg/dl Direct-2.9mg/dl Indirect-19.0mg/dl Serum Electrolytes Na-140mmol/L K-3.6mmol/l Cl-96.9mmol/l Serum Calcium-8.9mg/dl Serum creatinine-0.9mg/dl
  • 28.  Baby develope high grade fever  Temp 1040F  Antibiotic Changed Inj. Meropenam(40mg/kg/dose)
  • 29. On day 4 (80HOL)
  • 30.  Hb- 9.0gm/dl  Serum Billirubin- Total-7.8mg/dl Direct-0.8mg/dl Indirect-7.0mg/dl  Serum Electrolytes- Na-140.2mg/dl, K-3.8mg/dl, Cl-96.9mg/dl  Serum calcium-8.2mg/dl  Serum creatinine-0.8mg/dl
  • 31. Day C/C Temp Anaemia Jaundice Reflexes Manage ment Day5 Fever 102° F Pale Upto abdomen Moderate Continue photo therapy Day6 Fever 100° F Pale Face Good Transfusi on O-ve blood Day7 None 99°F Absent Face Good Medicati on as before
  • 32. Baby was discharged on day-9… Well alert Colour-pink. RR-42/min. HR-130/min. Mildly icteric. Hypertonic Sucking breast milk properly Medication-Tab.phenobarbitone(5mg/kg BD) Advice-Follow up after 7days Immunization. Exclusive breast feeding.
  • 33.  Baby active  Tone normal  Anaemia- absent  Jaundice- absent  Reflexes good