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BRAIN STEM
Ventral aspect of brainstem
Dorsal aspect of brainstem
Brainstem
 Performs spinal cord-like functions for the head
 Contains LMN for head muscles
 Initial processing of general afferent information
concerning head
Conduit function
 the only way for ascending tracts to reach the
thalamus or cerebellum, or for descending
tracts to reach the spinal cord, is by passing
through the brainstem.
 Ascending tracts reach thalamus and
cerebellum
 Descending tracts reach spinal cord
 Many tracts do not run through straight-
frequent involvement of relay nuclei
 Corticobulbar fibres descend to reach various
nuclei in brainstem
Cranial nerve functions
 Cranial nerves are head’s equivalent of spinal
nerves
 Involved in olfaction, sight, hearing,
equilibrium and taste
 Olfactory → telencephalon
 Optic → diencephalon
 The rest project to or emerge from brainstem
 Collection of sensory and motor nuclei
related to cranial nerve function at various
levels in brainstem
Integrative function
 Complex motor patterns
 Regulation of cardiovascular and respiratory
activity
 Some regulation of consciousness [function
of reticular formation in central core of
brainstem]
 Much of this is accomplished by the reticular
formation, which forms the central core of
the brainstem
Medulla
 The medulla is vaguely scoop .The "handle"
corresponds to the caudal or closed portion,
containing a central canal continuous with that
of the spinal cord.
 The open portion of the scoop corresponds to
the rostral or open medulla, in which the central
canal expands into the fourth ventricle.
 The apex of theV-shaped caudal fourth
ventricle, where it narrows into the central
canal, is called the obex
 The longitudinal grooves on the surface of
the spinal cord continue into the medulla,
more clearly at some levels than at others.
 They divide the surface of the caudal medulla
and part of the rostral medulla into a series of
columns that completely encircle it
 The anterior median fissure is briefly
interrupted by the pyramidal decussation at the
junction between spinal cord and brainstem, but
then it continues rostrally to the edge of the
pons, separating the two pyramids
The pons
 Pons is the Latin word for "bridge," and this
portion of it (called the basal pons) looks like a
bridge interconnecting the two cerebellar
hemispheres.
 It is not, however, a direct interconnection.
 Rather, many of the fibers descending in each
cerebral peduncle synapse in scattered nuclei of
the ipsilateral half of the basal pons.
 These nuclei in turn project their fibers across
the midline, after which they funnel into the
middle cerebellar peduncle (brachium
pontis) and finally enter the cerebellum
Transverse planes defining the subdivisions of the brainstem
C1 SEGMENT
SPINOMEDULLARY JUNCTION
MIDDLE OF MEDULLA OBLONGATA
UPPER MEDULLA
The Internal Structure of the Brainstem Reflects
Surface Features and the Position of Long Tracts
 The corticospinal and spinothalamic tracts have
consistent locations throughout the brainstem
 The three major longitudinal pathways
(corticospinal tract, poterior columns, and
spinothalamic tract) can be followed
systematically through the brainstem
 Two of the three stay in more or less the
same location throughout the brainstem.
 Corticospinal fibers travel in the most ventral
part of the brainstem, traversing the cerebral
peduncle, basal pons, and medullary
pyramid.
 At the spinomedullary junction, most of the
fibers in the pyramids decussate and form the
lateral corticospinal tracts
 The spinothalamic tract at all levels of the
brainstem is in or near the anterolateral
corner of the tegmentum, similar to its
position in the spinal cord.
 The posterior columns terminate in the
posterior column nuclei (nucleus gracilis and
nucleus cuneatus) of the medulla
Locations of the corticospinal tract, medial lemniscus,
spinothalamic tract, and reticular formation in the caudal and
rostral medulla (A, B), caudal pons and midpons(C, D) and caudal
and rostral midbrain (E, F)
 Efferent fibers from these nuclei decussate in
the medulla to form the medial lemniscus,
which reaches the thalamus
Major midline decussations
 The term decussation refers to the
intersection of matching fiber pathways as
they cross the midline on their way to or from
the brain.
 Two major sensory decussations are those of
the spinothalamic pathway in the spinal cord
and the posterior column-medial lemniscal
pathway in the medulla oblongata.
 A major cerebellar decussation is that of the
dentatothalamic tract in the midbrain.
 The pyramidal, motor decussation is in the
medulla oblongata and contains corticospinal
fibers crossing to the contralateral side of the
spinal cord.
 All four are brought into play by simply
clicking on a mouse
Afferents
Cerebellar controls
Motor output
General Arrangement of Cranial
Nerve Nuclei
 In the thoracic region of the developing spinal
cord, four distinct cell columns can be
identified in the gray matter on each side
 In the basal plate, the general somatic efferent
column supplies the striated muscles of the
trunk and limbs.
 The general visceral efferent column contains
preganglionic neurons of the autonomic
system.
 In the alar plate, the general visceral afferent
column receives afferents from thoracic and
abdominal organs.
 A general somatic afferent column receives
afferents from the body wall.
 In the brainstem, these four cell columns can
be identified
 they are fragmented
 not all contribute to each cranial nerve
Cell columns in brainstem and
their connections
General somatic efferent
(GSE) column.
 Supplies the striated musculature of the orbit
(via the oculomotor, trochlear, and abducens
nerves) and tongue (via the hypoglossal nerve).
General visceral efferent
(GVE) column
 Gives rise to the cranial parasympathetic
system
 The target ganglia are the ciliary,
pterygopalatine, otic, and submandibular
ganglia in the head, and the vagal ganglia in
the thorax and abdomen
General visceral afferent
column.
 Receives from the visceral territory of the
glossopharyngeal and vagus nerves.
General somatic afferent
column.
 Receives from skin and mucous membranes,
mainly in trigeminal nerve territory whose
most important components are
1. the skin and mucous membranes of the
oronasofacial region
2. the dura mater.
 Three additional cell columns serve
pharyngeal arch derivatives and the inner ear.
Special visceral efferent
column
 To pharyngeal arch musculature of face, jaws,
palate, larynx, and pharynx (via facial,
trigeminal, glossopharyngeal, vagus, and
cranial accessory nerves).
 These striated muscles have visceral
functions in relation to food and air intake
(hence, visceral).
Special visceral afferent
column.
 Receives from taste buds located in the
endoderm lining the pharyngeal arches.
Special sense afferent
column
 Receives vestibular (balance) and cochlear
(hearing) from the inner ear.
Components of inferior cerebellar
peduncle
Brainstem.ppt
Brainstem.ppt
Brainstem.ppt
Brainstem.ppt
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Brainstem.ppt

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Brainstem.ppt

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  • 5. Ventral aspect of brainstem
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  • 7. Dorsal aspect of brainstem
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  • 14. Brainstem  Performs spinal cord-like functions for the head  Contains LMN for head muscles  Initial processing of general afferent information concerning head
  • 15. Conduit function  the only way for ascending tracts to reach the thalamus or cerebellum, or for descending tracts to reach the spinal cord, is by passing through the brainstem.
  • 16.  Ascending tracts reach thalamus and cerebellum  Descending tracts reach spinal cord  Many tracts do not run through straight- frequent involvement of relay nuclei
  • 17.  Corticobulbar fibres descend to reach various nuclei in brainstem
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  • 19. Cranial nerve functions  Cranial nerves are head’s equivalent of spinal nerves  Involved in olfaction, sight, hearing, equilibrium and taste  Olfactory → telencephalon  Optic → diencephalon
  • 20.  The rest project to or emerge from brainstem  Collection of sensory and motor nuclei related to cranial nerve function at various levels in brainstem
  • 21. Integrative function  Complex motor patterns  Regulation of cardiovascular and respiratory activity  Some regulation of consciousness [function of reticular formation in central core of brainstem]
  • 22.  Much of this is accomplished by the reticular formation, which forms the central core of the brainstem
  • 23. Medulla  The medulla is vaguely scoop .The "handle" corresponds to the caudal or closed portion, containing a central canal continuous with that of the spinal cord.  The open portion of the scoop corresponds to the rostral or open medulla, in which the central canal expands into the fourth ventricle.
  • 24.  The apex of theV-shaped caudal fourth ventricle, where it narrows into the central canal, is called the obex  The longitudinal grooves on the surface of the spinal cord continue into the medulla, more clearly at some levels than at others.
  • 25.  They divide the surface of the caudal medulla and part of the rostral medulla into a series of columns that completely encircle it  The anterior median fissure is briefly interrupted by the pyramidal decussation at the junction between spinal cord and brainstem, but then it continues rostrally to the edge of the pons, separating the two pyramids
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  • 30. The pons  Pons is the Latin word for "bridge," and this portion of it (called the basal pons) looks like a bridge interconnecting the two cerebellar hemispheres.  It is not, however, a direct interconnection.  Rather, many of the fibers descending in each cerebral peduncle synapse in scattered nuclei of the ipsilateral half of the basal pons.
  • 31.  These nuclei in turn project their fibers across the midline, after which they funnel into the middle cerebellar peduncle (brachium pontis) and finally enter the cerebellum
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  • 33. Transverse planes defining the subdivisions of the brainstem
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  • 38. MIDDLE OF MEDULLA OBLONGATA
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  • 42. The Internal Structure of the Brainstem Reflects Surface Features and the Position of Long Tracts  The corticospinal and spinothalamic tracts have consistent locations throughout the brainstem  The three major longitudinal pathways (corticospinal tract, poterior columns, and spinothalamic tract) can be followed systematically through the brainstem
  • 43.  Two of the three stay in more or less the same location throughout the brainstem.  Corticospinal fibers travel in the most ventral part of the brainstem, traversing the cerebral peduncle, basal pons, and medullary pyramid.  At the spinomedullary junction, most of the fibers in the pyramids decussate and form the lateral corticospinal tracts
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  • 45.  The spinothalamic tract at all levels of the brainstem is in or near the anterolateral corner of the tegmentum, similar to its position in the spinal cord.  The posterior columns terminate in the posterior column nuclei (nucleus gracilis and nucleus cuneatus) of the medulla
  • 46. Locations of the corticospinal tract, medial lemniscus, spinothalamic tract, and reticular formation in the caudal and rostral medulla (A, B), caudal pons and midpons(C, D) and caudal and rostral midbrain (E, F)
  • 47.  Efferent fibers from these nuclei decussate in the medulla to form the medial lemniscus, which reaches the thalamus
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  • 53. Major midline decussations  The term decussation refers to the intersection of matching fiber pathways as they cross the midline on their way to or from the brain.  Two major sensory decussations are those of the spinothalamic pathway in the spinal cord and the posterior column-medial lemniscal pathway in the medulla oblongata.
  • 54.  A major cerebellar decussation is that of the dentatothalamic tract in the midbrain.  The pyramidal, motor decussation is in the medulla oblongata and contains corticospinal fibers crossing to the contralateral side of the spinal cord.  All four are brought into play by simply clicking on a mouse
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  • 60. General Arrangement of Cranial Nerve Nuclei
  • 61.  In the thoracic region of the developing spinal cord, four distinct cell columns can be identified in the gray matter on each side  In the basal plate, the general somatic efferent column supplies the striated muscles of the trunk and limbs.
  • 62.  The general visceral efferent column contains preganglionic neurons of the autonomic system.  In the alar plate, the general visceral afferent column receives afferents from thoracic and abdominal organs.  A general somatic afferent column receives afferents from the body wall.
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  • 64.  In the brainstem, these four cell columns can be identified  they are fragmented  not all contribute to each cranial nerve
  • 65. Cell columns in brainstem and their connections
  • 66. General somatic efferent (GSE) column.  Supplies the striated musculature of the orbit (via the oculomotor, trochlear, and abducens nerves) and tongue (via the hypoglossal nerve).
  • 67. General visceral efferent (GVE) column  Gives rise to the cranial parasympathetic system  The target ganglia are the ciliary, pterygopalatine, otic, and submandibular ganglia in the head, and the vagal ganglia in the thorax and abdomen
  • 68. General visceral afferent column.  Receives from the visceral territory of the glossopharyngeal and vagus nerves.
  • 69. General somatic afferent column.  Receives from skin and mucous membranes, mainly in trigeminal nerve territory whose most important components are 1. the skin and mucous membranes of the oronasofacial region 2. the dura mater.
  • 70.  Three additional cell columns serve pharyngeal arch derivatives and the inner ear.
  • 71. Special visceral efferent column  To pharyngeal arch musculature of face, jaws, palate, larynx, and pharynx (via facial, trigeminal, glossopharyngeal, vagus, and cranial accessory nerves).  These striated muscles have visceral functions in relation to food and air intake (hence, visceral).
  • 72. Special visceral afferent column.  Receives from taste buds located in the endoderm lining the pharyngeal arches.
  • 73. Special sense afferent column  Receives vestibular (balance) and cochlear (hearing) from the inner ear.
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  • 81. Components of inferior cerebellar peduncle