In-class student presentation assignment
Each presentation will last from 5 to 10 minutes, during which time, each student will be asked to read the title of their research paper from the list of approved research paper topics provided, read a statement of their pros and cons and summarize their research paper’s conclusions. In the interest of time, students will be required to omit the use of visual aids, electronic or otherwise during the presentation. Rather than an assignment centered around electronic displays of slides, graphs and tables --typically presented in rapid succession, students will be encouraged to think of themselves as “attorneys” or “policy scientists” or “policy makers” making a final summation of an argument before a jury of their peers or constituents instead of an image of themselves making a typical video or Power point presentation before a class of their peers. Not only will such an approach place the emphasis on persuasion and strength of argument, it will also eliminate technology and more precisely any possible glitches in the technology occurring during the course of the presentation, from unduly influencing the student’s presentation grade.
Each student must also defend their research paper conclusions and answer any questions raised by students and/or the Instructor, at the time of the in-class presentation. No-shows will receive the score of “0” for the assignments while late presentations, if accepted, will receive a 40 point-late penalty. Presentations will NOT be made after the “last-day-of-classes” point in the semester. Students will be encouraged to take the paper presentation deadline seriously and allowed and indeed encouraged to complete the presentation before their scheduled presentation date to avoid unforeseen circumstances that may cause them to fail to present on time. The paper presentation provides a total of 100 points and represents 25% of the student’s final grade.
Frequent reminders of this important assignment will be made by the Instructor throughout the course of the semester. Of course, students with questions and/or concerns regarding the paper presentation assignment are required to notify the Instructor at the earliest possible time.
1
Effect of Self-efficacy and Depression on Quality of Life in Outpatients with CHF
Ashmita Singh
College of Nursing and Health Innovation, The University of Texas Arlington
NURS-3321: Nursing Research
Maxine Adegbola, PhD, CNE, RN, ANEF
October 2, 2021
Effect of Self-efficacy and Depression on Quality of Life in Outpatients with CHF
Heart disease is one of the leading causes of death among people with different racial and ethnic groups all over the world. Heart failure occurs when the heart cannot pump enough blood and oxygen to support other organs in our body. Although it is a very serious condition, it doesn’t mean that the heart has stopped beating but it causes people to have difficult time performing their daily activitie ...
In this module, we examined crimes against persons, crimes against p.docxLizbethQuinonez813
In this module, we examined crimes against persons, crimes against property, and white-collar crimes. These crimes are all treated differently by the legislature as well as the media. These differences are a reflection of how society views them. As you consider these differences, you should also consider how these differences have evolved over time.
Tasks:
Prepare a 3- to 5-page report that describes all of the following points:
The differences in the treatment of each type of crime by the legislature. Explore the different crime levels (misdemeanor
vs.
felony) and different punishments.
The differences in the descriptions utilized by the media. How does the media depict the different types of criminals? Have there been any changes?
The differences in the theoretical applications for these types of crimes. How do the theories differentiate between these types of criminal behavior?
Submission Details:
.
In this module, we explore how sexual identity impacts the nature of.docxLizbethQuinonez813
In this module, we explore how sexual identity impacts the nature of friendship for all of us. With the legalization of gay marriages and rise of alternative unions, as well as the sociocultural prevalence of much wider acceptance of Lesbian, Gay, Bisexual, Transgender, and Queer identity definitions in society, we are witnessing expanded definitions, beliefs, and values regarding sexual self-identity and the dynamics of friendship.
Philosopher Michael Foucault argues that we have an opportunity to expand our understanding of friendship, beyond the state of the current realm, where our connections remain quite limited: “Society and the institutions which frame it have limited the possibility of relationships (to marriage) because a rich, relational world would be very complex to manage” (p. 207).
Your initial post should be at least 250 words and must provide a minimum of one cited reference in APA style. For assistance with APA style formatting, visit the
Library
or the
Excelsior OWL
.
Please answer one of the following:
How do you perceive changes in social stereotypes, issues, and judgments regarding sexualities as potentially impacting changes in friendship, in the relationships, cultural expressions, and understandings of friendships?
Do you think that the social expansion of acceptance of "LGBTQ" identities and relationships has an impact upon the dynamics of friendship generally in the society?
Do you think that this has changed your own perspective?
.
In this module, we have studied Cultural Imperialism and Americaniza.docxLizbethQuinonez813
In this module, we have studied Cultural Imperialism and Americanization. For this essay, you will address how Disney might be considered as a leading force of US imperialism. Do you agree with this concept? Why or why not? Give examples. This paper should be 2 pages, in APA style, 2-3 scholarly article as a minimum should be included in your essay.
.
In this Reflection Activity, you will be asked to think and write ab.docxLizbethQuinonez813
In this Reflection Activity, you will be asked to think and write about an important issue or theme from the chapter. Your response will be submitted directly to the instructor, rather than shared with the class. First, read the prompt below. Then, respond to the question(s) asked at the bottom of the activity. Follow your instructor’s guidelines in terms of word count and content.
The most visible manifestation of the Renaissance comes from artistic genius and innovation, but the defining feature of the period is an outlook or worldview called humanism. Both of these developed in a particular set of circumstances, a unique historical context that characterized the northern Italian city-states and that we call the Renaissance. Their dominance of Mediterranean trade made these Italian cities into prosperous commercial centers where powerful merchants displaced the old landed aristocracy in positions of power and influence. The resulting social structure bore little resemblance to the traditional ordered society of the Middle Ages. Another point of uniqueness was Italian cities’ relatively independent political development that led first to republican forms and then to despotism. In the process, they laid the foundations for modern political thought.
Of these two sets of circumstances, the political and the economic, which do you think was most important in creating an environment ripe for the Renaissance to flourish? Why?
.
In this lab, you will observe the time progression of industrializat.docxLizbethQuinonez813
In this lab, you will observe the time progression of industrialization and human development to help you write up a scientific paper that centers on the following:
If current human development does not change, will groundwater sustainability be affected? Explain your observations.
Human Impacts on the Sustainability of Groundwater
Sustainability is based on a simple principle: Everything that is needed for survival and well-being depends either directly or indirectly on the natural environment. Sustainability creates and maintains the conditions under which humans and nature can exist in productive harmony, while also helping to fulfill the social and economic requirements of present and future generations.
Part 1
:
Background Information
Planet Earth’s surface is over 70% water, but less than 1% of the water on Earth is considered accessible, usable freshwater for sustaining humans’ and other organisms’ lives. Of the accessible freshwater, approximately 99% is located in aquifers, natural underground water chambers, and other groundwater sources. Unfortunately, humans are depleting the aquifers faster than they can be recharged by the hydrological cycle. Therefore, three quarters of groundwater is considered nonrenewable.
Conditions
The main reason we using groundwater resources mainly for drinking and irrigation. As a result, this not only decreases an important source of freshwater—it also can cause pollution of that groundwater by saltwater intrusion. The recharge rate of groundwater is further hindered by land clearing and deforestation caused by human development. When land is cleared for human development, more flooding occurs, the
transpiration rate
(the amount of water that evaporates into the atmosphere from plants) is reduced, and rainwater is inhibited from adequately
percolating
(penetrating the soil) into the ground to allow for aquifers and groundwater to be recharged.
Figure below shows Saltwater Intrusion
:
(Wright & Boorse, 2010)
Impacts
Forty percent of the world’s food is produced via irrigation. As a result, if the current rate of groundwater usage continues, food production could be drastically reduced worldwide. This reduction in food supply would be detrimental in sustaining the projected worldwide human population of over 10 billion within the next 50 years.
Part 2:
Timeline
Use the Hydrologic Cycle Figure below to understand the impact of industrialization and human development on ground water over 3 centuries.
(Wright & Boorse, 2010)
The table below shows the impacts
:
Reference
:
Wright, R. T., & Boorse, D. F. (2010).
Environmental science: Toward a sustainable future
. (11th ed.) White Plains, NY: Addison Wesley.
.
In this module we have discussed an organizations design and how it.docxLizbethQuinonez813
In this module we have discussed an organization's design and how it lays out the foundation for an organization to operate. An important part of an organization's design is its structures and roles.
Write a 1-2 page paper analyzing an organization's structure and roles and cover the following:
Write a 1 paragraph introduction to briefly explain an organization's structure and roles
Discuss the importance of having an organizational structure.
Explain the importance of roles within an organization.
Provide 2 resources.
.
In this lab, you will gather data about CO2 emissions using the .docxLizbethQuinonez813
In this lab, you will gather data about CO
2
emissions using the National Oceanic and Atmospheric Administration Web site (Earth System Research Laboratory, n.d.) to help you write up a scientific report centered around known phenomena of CO
2
emissions, related to the following question:
Would you expect to see an increase or decrease in CO
2
emissions in the data over the past 40 years? Why?
Part 1
:
Introduction
The natural balance that occurs between global atmospheric cooling and warming processes provides an important contribution to the Earth’s varied climates.
Troposphere gases
Planetary albedo from clouds low in the troposphere, sulfur dioxide (SO
2
) from active volcanoes, snow, and ice all reflect incoming solar radiation back into space. This causes a
cooling
effect on climates within a geographical area.
Clouds
high
in the troposphere and greenhouse gases such as water vapor(H
2
O), carbon dioxide (CO
2
) , methane (CH
4
) , and nitrous oxide (N
2
O) have a
warming
effect.
Along with the solar activity, these cooling and warming processes help ensure that the planet’s average surface temperature is a net value that is above freezing, helping to ensure that life is possible.
Theory on CO
2
Emissions
It has been hypothesized that anthropogenic effects (conditions caused by human activity) that are associated with industry, agriculture, and fossil fuel use have enhanced these warming processes by contributing greenhouse gases such as N
2
O, CH
4
,and CO
2
into the troposphere. As a result, CO
2
is believed to contribute the most to the atmospheric warming process.
Pollution
Pollution
is a substance that produces a detrimental change in the environment because of its composition and abundance. Anthropogenic sources of CO
2
fit this description because of the perception that there is evidence of a positive correlation between the increases in anthropogenic CO
2
and increases in temperature. In turn, as temperatures increase, climates can change worldwide, unbalancing ecosystems across the globe.
Strategies
Strategies and prediction models can be used to decrease or eliminate the effects that are associated with a particular pollutant. First, the cause of the pollution must be identified. Then, scientists can create innovate ways to reduce or eliminate its production.
Part 2:
Earth System Research Laboratory
Click on the
National Oceanic and Atmospheric Administration Earth System Research Laboratory, Global Monitoring Division Website.
or
https://www.esrl.noaa.gov/gmd/obop/
(Earth System Research Laboratory, n.d.). Here you will identify important sources of CO
2
emission to help you complete your lab assignment.
Reference
Earth system research laboratory: Global monitoring division
. (n.d.). Retrieved from the U.S. Department of Commerce, National Oceanic and Atmospheric Administration Research Web site: http://www.esrl.noaa.gov/gmd/obop//
.
In this five-page essay, your task is to consider how Enlightenment .docxLizbethQuinonez813
In this five-page essay, your task is to consider how Enlightenment philosophes sought change in their societies. Select a theme from Voltaire's Candide (for example, religion, government, slavery, marriage, patriarchy, etc.) and explain how Voltaire satirizes it as a way of calling for reform. Contextualize Voltaire's argument by incorporating one or two articles from the Encyclopedie, which you can find here:
https://quod.lib.umich.edu/d/did/
Your bibliography should include two or three sources: Voltaire's novel and one or two Encyclopedie articles. About five double-spaced pages, Due on 02/21/2017
.
In this module, we examined crimes against persons, crimes against p.docxLizbethQuinonez813
In this module, we examined crimes against persons, crimes against property, and white-collar crimes. These crimes are all treated differently by the legislature as well as the media. These differences are a reflection of how society views them. As you consider these differences, you should also consider how these differences have evolved over time.
Tasks:
Prepare a 3- to 5-page report that describes all of the following points:
The differences in the treatment of each type of crime by the legislature. Explore the different crime levels (misdemeanor
vs.
felony) and different punishments.
The differences in the descriptions utilized by the media. How does the media depict the different types of criminals? Have there been any changes?
The differences in the theoretical applications for these types of crimes. How do the theories differentiate between these types of criminal behavior?
Submission Details:
.
In this module, we explore how sexual identity impacts the nature of.docxLizbethQuinonez813
In this module, we explore how sexual identity impacts the nature of friendship for all of us. With the legalization of gay marriages and rise of alternative unions, as well as the sociocultural prevalence of much wider acceptance of Lesbian, Gay, Bisexual, Transgender, and Queer identity definitions in society, we are witnessing expanded definitions, beliefs, and values regarding sexual self-identity and the dynamics of friendship.
Philosopher Michael Foucault argues that we have an opportunity to expand our understanding of friendship, beyond the state of the current realm, where our connections remain quite limited: “Society and the institutions which frame it have limited the possibility of relationships (to marriage) because a rich, relational world would be very complex to manage” (p. 207).
Your initial post should be at least 250 words and must provide a minimum of one cited reference in APA style. For assistance with APA style formatting, visit the
Library
or the
Excelsior OWL
.
Please answer one of the following:
How do you perceive changes in social stereotypes, issues, and judgments regarding sexualities as potentially impacting changes in friendship, in the relationships, cultural expressions, and understandings of friendships?
Do you think that the social expansion of acceptance of "LGBTQ" identities and relationships has an impact upon the dynamics of friendship generally in the society?
Do you think that this has changed your own perspective?
.
In this module, we have studied Cultural Imperialism and Americaniza.docxLizbethQuinonez813
In this module, we have studied Cultural Imperialism and Americanization. For this essay, you will address how Disney might be considered as a leading force of US imperialism. Do you agree with this concept? Why or why not? Give examples. This paper should be 2 pages, in APA style, 2-3 scholarly article as a minimum should be included in your essay.
.
In this Reflection Activity, you will be asked to think and write ab.docxLizbethQuinonez813
In this Reflection Activity, you will be asked to think and write about an important issue or theme from the chapter. Your response will be submitted directly to the instructor, rather than shared with the class. First, read the prompt below. Then, respond to the question(s) asked at the bottom of the activity. Follow your instructor’s guidelines in terms of word count and content.
The most visible manifestation of the Renaissance comes from artistic genius and innovation, but the defining feature of the period is an outlook or worldview called humanism. Both of these developed in a particular set of circumstances, a unique historical context that characterized the northern Italian city-states and that we call the Renaissance. Their dominance of Mediterranean trade made these Italian cities into prosperous commercial centers where powerful merchants displaced the old landed aristocracy in positions of power and influence. The resulting social structure bore little resemblance to the traditional ordered society of the Middle Ages. Another point of uniqueness was Italian cities’ relatively independent political development that led first to republican forms and then to despotism. In the process, they laid the foundations for modern political thought.
Of these two sets of circumstances, the political and the economic, which do you think was most important in creating an environment ripe for the Renaissance to flourish? Why?
.
In this lab, you will observe the time progression of industrializat.docxLizbethQuinonez813
In this lab, you will observe the time progression of industrialization and human development to help you write up a scientific paper that centers on the following:
If current human development does not change, will groundwater sustainability be affected? Explain your observations.
Human Impacts on the Sustainability of Groundwater
Sustainability is based on a simple principle: Everything that is needed for survival and well-being depends either directly or indirectly on the natural environment. Sustainability creates and maintains the conditions under which humans and nature can exist in productive harmony, while also helping to fulfill the social and economic requirements of present and future generations.
Part 1
:
Background Information
Planet Earth’s surface is over 70% water, but less than 1% of the water on Earth is considered accessible, usable freshwater for sustaining humans’ and other organisms’ lives. Of the accessible freshwater, approximately 99% is located in aquifers, natural underground water chambers, and other groundwater sources. Unfortunately, humans are depleting the aquifers faster than they can be recharged by the hydrological cycle. Therefore, three quarters of groundwater is considered nonrenewable.
Conditions
The main reason we using groundwater resources mainly for drinking and irrigation. As a result, this not only decreases an important source of freshwater—it also can cause pollution of that groundwater by saltwater intrusion. The recharge rate of groundwater is further hindered by land clearing and deforestation caused by human development. When land is cleared for human development, more flooding occurs, the
transpiration rate
(the amount of water that evaporates into the atmosphere from plants) is reduced, and rainwater is inhibited from adequately
percolating
(penetrating the soil) into the ground to allow for aquifers and groundwater to be recharged.
Figure below shows Saltwater Intrusion
:
(Wright & Boorse, 2010)
Impacts
Forty percent of the world’s food is produced via irrigation. As a result, if the current rate of groundwater usage continues, food production could be drastically reduced worldwide. This reduction in food supply would be detrimental in sustaining the projected worldwide human population of over 10 billion within the next 50 years.
Part 2:
Timeline
Use the Hydrologic Cycle Figure below to understand the impact of industrialization and human development on ground water over 3 centuries.
(Wright & Boorse, 2010)
The table below shows the impacts
:
Reference
:
Wright, R. T., & Boorse, D. F. (2010).
Environmental science: Toward a sustainable future
. (11th ed.) White Plains, NY: Addison Wesley.
.
In this module we have discussed an organizations design and how it.docxLizbethQuinonez813
In this module we have discussed an organization's design and how it lays out the foundation for an organization to operate. An important part of an organization's design is its structures and roles.
Write a 1-2 page paper analyzing an organization's structure and roles and cover the following:
Write a 1 paragraph introduction to briefly explain an organization's structure and roles
Discuss the importance of having an organizational structure.
Explain the importance of roles within an organization.
Provide 2 resources.
.
In this lab, you will gather data about CO2 emissions using the .docxLizbethQuinonez813
In this lab, you will gather data about CO
2
emissions using the National Oceanic and Atmospheric Administration Web site (Earth System Research Laboratory, n.d.) to help you write up a scientific report centered around known phenomena of CO
2
emissions, related to the following question:
Would you expect to see an increase or decrease in CO
2
emissions in the data over the past 40 years? Why?
Part 1
:
Introduction
The natural balance that occurs between global atmospheric cooling and warming processes provides an important contribution to the Earth’s varied climates.
Troposphere gases
Planetary albedo from clouds low in the troposphere, sulfur dioxide (SO
2
) from active volcanoes, snow, and ice all reflect incoming solar radiation back into space. This causes a
cooling
effect on climates within a geographical area.
Clouds
high
in the troposphere and greenhouse gases such as water vapor(H
2
O), carbon dioxide (CO
2
) , methane (CH
4
) , and nitrous oxide (N
2
O) have a
warming
effect.
Along with the solar activity, these cooling and warming processes help ensure that the planet’s average surface temperature is a net value that is above freezing, helping to ensure that life is possible.
Theory on CO
2
Emissions
It has been hypothesized that anthropogenic effects (conditions caused by human activity) that are associated with industry, agriculture, and fossil fuel use have enhanced these warming processes by contributing greenhouse gases such as N
2
O, CH
4
,and CO
2
into the troposphere. As a result, CO
2
is believed to contribute the most to the atmospheric warming process.
Pollution
Pollution
is a substance that produces a detrimental change in the environment because of its composition and abundance. Anthropogenic sources of CO
2
fit this description because of the perception that there is evidence of a positive correlation between the increases in anthropogenic CO
2
and increases in temperature. In turn, as temperatures increase, climates can change worldwide, unbalancing ecosystems across the globe.
Strategies
Strategies and prediction models can be used to decrease or eliminate the effects that are associated with a particular pollutant. First, the cause of the pollution must be identified. Then, scientists can create innovate ways to reduce or eliminate its production.
Part 2:
Earth System Research Laboratory
Click on the
National Oceanic and Atmospheric Administration Earth System Research Laboratory, Global Monitoring Division Website.
or
https://www.esrl.noaa.gov/gmd/obop/
(Earth System Research Laboratory, n.d.). Here you will identify important sources of CO
2
emission to help you complete your lab assignment.
Reference
Earth system research laboratory: Global monitoring division
. (n.d.). Retrieved from the U.S. Department of Commerce, National Oceanic and Atmospheric Administration Research Web site: http://www.esrl.noaa.gov/gmd/obop//
.
In this five-page essay, your task is to consider how Enlightenment .docxLizbethQuinonez813
In this five-page essay, your task is to consider how Enlightenment philosophes sought change in their societies. Select a theme from Voltaire's Candide (for example, religion, government, slavery, marriage, patriarchy, etc.) and explain how Voltaire satirizes it as a way of calling for reform. Contextualize Voltaire's argument by incorporating one or two articles from the Encyclopedie, which you can find here:
https://quod.lib.umich.edu/d/did/
Your bibliography should include two or three sources: Voltaire's novel and one or two Encyclopedie articles. About five double-spaced pages, Due on 02/21/2017
.
In this reflection, introduce your professor to your project. Speak .docxLizbethQuinonez813
In this reflection, introduce your professor to your project. Speak about the pro and con sides of the controversy, and present your thesis statement. Then, consider some of the following questions as you reflect upon the road so far. If you want to, explain a little bit about your process. What have you experienced so far in writing your paper? Was it difficult or fairly easy to come up with your design? Do you feel confident about your progress so far? How do you feel about your thesis statement? What would you like to do in revisions? What step seems the most difficult or the easiest for you?
Your response should be at least 200 words. No references or citations are necessary.
.
In this discussion, please address the followingDiscuss how oft.docxLizbethQuinonez813
A project schedule should be reviewed regularly, such as weekly, by the project manager and team to track progress and make adjustments if needed. While the project manager and team should review the schedule primarily, it can also be beneficial to get input from other stakeholders. Creating a project schedule has advantages like helping define deliverables, estimate resources and time needed, and coordinate tasks. However, schedules also require ongoing maintenance and updates as the project evolves.
In this course, we have introduced and assessed many noteworthy figu.docxLizbethQuinonez813
In this course, we have introduced and assessed many noteworthy figures related to the colonizing and first 90 years of the United States. For this assignment, you will choose a significant figure who contributed to and influenced others during the time discussed in this course—with the exception of any U.S. President—and prepare a tribute focusing on his or her relevance to today. This is not a biography. Your argument should highlight how society remembers your historical figure now, based on the philosophies and ideals he or she presented or helped to change and evolve.
The style of this project is a multimedia presentation with both audio and video components; however, the medium used is up to you. Potential examples include, but are not limited to, a videotaped speech, a self-guided PowerPoint presentation, or a video with audio. Creativity and effort will impact the final grade.
Projects are due during Unit VII and will be graded on the following:
Prepare and submit a two-page reflection, ideally based on the outline assignment from Unit VI.
Create and submit a visual presentation with your reflection as an audio transcript.
Use a minimum two sources that can be found in CSU’s Online Library (at least one from the American History & Life database).
Proper citations and references for any use or identification of those sources must be used.
Length must fall within three to five minutes; in the case of PowerPoint, slides and audio should progress and stop automatically like a taped presentation.
Content accuracy and avoidance of anachronism are a must.
.
In this Assignment, you will focus on Adaptive Leadership from a.docxLizbethQuinonez813
In this Assignment, you will focus on Adaptive Leadership from a global perspective. When approaching this Assignment, do so from an international and global view
PLEASE SEE ATTACHED RUBRIC AND FOLLOW AS DIRECTED
NOTE THE PROGRAM : TURNITIN WILL BE USED TO DETECT A CERTAIN PERCENTAGE OF ORGINALITY
.
Inferential Analysis
Chapter 20
NUR 6812Nursing Research
Florida National University
Introduction - Inferential Analysis
We will discuss analysis of variance and regression, which are technically part of the same family of statistics known as the general linear method but are used to achieve different analytical goals
ANALYSIS OF VARIANCE
Analysis of variance (ANOVA) is used so often that Iversen and Norpoth (1987) said they once had a student who thought this was the name of an Italian statistician.
You can think of analysis of variance as a whole family of procedures beginning with the simple and frequently used t-test and becoming quite complicated with the use of multiple dependent variables (MANOVA, to be explained later in this chapter) and covariates.
Although the simpler varieties of these statistics can actually be calculated by hand, it is assumed that you will use a statistical software package for your calculations.
If you want to see how these calculations are done, you could try to compute a correlation, chi-square, t-test, or ANOVA yourself (see Yuker, 1958; Field, 2009), but in general it is too time consuming and too subject to human error to do these by hand.
IMPORTANT TERMINOLOGY
Several terms are used in these analyses that you need to be familiar with to understand the analyses themselves and the results. Many will already be familiar to you.
Statistical significance: This indicates the probability that the differences found are a result of error, not the treatment. Stated in terms of the P value, the convention is to accept either a 1% (P ≤ 0.01), or 1 out of 100, or 5% (P ≤ 0.05), or 5 out of 100, possibility that any differences seen could have been due to error (Cortina & Dunlap, 2007).
Research hypothesis: A research hypothesis is a declarative statement of the expected relationship between the dependent and independent variable(s).
Null hypothesis: The null hypothesis, based on the research hypothesis, states that the predicted relationships will not be found or that those found could have occurred by chance, meaning the difference will not be statistically significant.
Effect size: This is defined by Cortina and Dunlap as “the amount of variance in one variable accounted for by another in the sample at hand” (2007, p. 231). Effect size estimates are helpful adjuncts to significance testing. An important limitation, however, is that they are heavily influenced by the type of treatment or manipulation that occurred and the measures that are used.
Confidence intervals: Although sometimes suggested as an adjunct or replacement for the significance level, confidence intervals are determined in part by the alpha (significance level) (Cortina & Dunlap, 2007). Likened to a margin of error, the confidence intervals indicate the range within which the true difference between means may lie. A narrow confidence interval implies high precision; we can specify believable values within a narrow range ...
Infancy to Early Childhood Case AnalysisPart IFor this diLizbethQuinonez813
Infancy to Early Childhood Case Analysis
Part I:
For this discussion board assignment, you will conduct an interview with a parent who has a child in the early childhood stage of development. In your interview, solicit information to understand the child's development from infancy to early childhood about the area of development assigned to you.
--please explore the social needs of the child's development.
Social Needs: For social needs, use Erikson's psychosocial theory of development.
ALL students should also explore how multi-cultural factors have impacted the area of development you are exploring (i.e., ethnicity, race, gender, socioeconomic status, ableism, religion, sexual orientation and other sub-cultural influences such as military). There are two optional videos in the learning module that will help you think about culture more deeply and generate ideas about possible areas/questions to explore with your interviewee.
Quality posts will integrate material from the textbook to support your analysis of the child's development. All material from the textbook should be cited in APA style. Students should define psychological terms and concepts used; assume your audience is not familiar with developmental psychology.
...
Infectious Diseases
Name
Course
Instructor
Date
Introduction
Infectious infections have created increased attention.
Covid-19 is the most recent challenges caused by infectious diseases.
https://idpjournal.biomedcentral.com/
Introduction
Infectious infections have created increased attention, especially after several outbreaks and pandemics that altered human health globally. Covid-19 and the related infections are the most recent challenges caused by infectious diseases affecting the whole world. This presentation illustrates common infectious diseases in the nature they are caused, their diagnosis, treatment, and possible prevention methods. It shall also describe the common symptoms of infectious diseases and when to seek medical attention.
2
Overview
Overview
Infectious diseases have attracted increased attention globally because of their various occurrence. Its symptoms range from mild to severe, and the treatment and management depend on the cause of infection. Infectious diseases are caused by several pathogens, such as bacteria, viruses, parasites, and fungi, to mention a few. Transmission of pathogens in humans happens in numerous ways, including direct transmission through contact, water, and foodborne infections. Infection from insects such as ticks and mosquitoes can also effectively transmit pathogens.
3
Infectious diseases have numerous occurrences.
Symptoms range from mild to severe.
Pathogens include bacteria, viruses, parasites, and fungi.
Transmission include through contact, water and food, and insects.
Individuals with a higher risk of infectious diseases
All individuals are at risk of contracting infectious diseases.
Individuals with compromised immune systems are at higher risk.
They include;
People with suppressed immunities.
People unvaccinated for certain infectious diseases
Children and healthcare workers.
https://www.youtube.com/watch?v=9axOFtPqS0c
Individuals with a higher risk of infectious diseases
All individuals are at risk of contracting infectious diseases. However, individuals with compromised immune systems are at higher risk of getting infectious diseases. Individuals at higher risks of getting infectious diseases include; people with suppressed immunities, such as patients of cancer, HIV, and recent organ transmissions. People unvaccinated for certain infectious diseases are also considered at higher risk of getting infectious diseases. Other individuals at higher risks of getting infectious diseases are children and healthcare workers.
4
How Common are infectious diseases?
How Common are infectious diseases?
Infectious diseases are common worldwide. Some infectious diseases are more common and strike more often than others. For instance, infections caused by E. coli are common and may not require medications because they may cause mild signs of complications. In the United States, a fifth of the population is infected with influenza annually. This indicates that infectiou ...
Individual Focused Learning for Better Memory Retention Through LizbethQuinonez813
Individual Focused Learning for Better Memory Retention Through Experience
CONFIDENTIAL
GCU – For Internal Use Only
1
Literature Review: Background to the Problem
10/9/2019
Cognitive theory focuses on experiences in three looping processes, comprehension, memory, and application
According to Goossens (2020), cognitive theories in learning is affected by biology, environment, and social constructs
Bottom-up and top-down influences define experience of learning and thus memory and its retention (Tyng et al., 2017)
Comprehension is interpretative with different people and methodologies of gaining skills require support for better retention of knowledge (Ford et al., 2020)
CONFIDENTIAL
GCU – For Internal Use Only
Objective:
The outline on this slide is used in the Prospectus to develop the Background of the Study in Chapter 1 and the Background of the Problem Space in Chapter 2.
Slide Requirements:
Use either a bulleted format or table format
Describe what is already understood about the problem - Historically, memory retention is dependent on biology, social determinants, and educational roles (Berger et al., 2012)
Present findings from prior research related to the history of the problem space – individual are unique by circumstances, cognition development is different for each person hence memory retention and its experiences are unique. In education sector today, curriculum caters to meeting outcomes of the larger group with less focus on individual pace of learning.
Focus on:
When the problem started – generalization of education and learning environment through general curriculum tends to segregate some learners
What has been discovered about the problem - According to Tyng et al. (2017), “the effects of emotion on learning and memory are not always univalent” it points to the fact that progression is a personal journey such that how learning is understood is directly linked to how it is taught, the environment it is taught in, and the emotional attachments of information processing. Therefore, productivity in learning can only be attained by training and task definition which can be versatile form one person to another.
The current state of the problem – Development of separate special classes for students with learning challenge is beneficial but with poor education systems, the program could be detrimental for the future especially in self teaching learners. With guidance for retention of knowledge being a taught skill, ineffective environments and lack of support could be detrimental especially to disadvantaged communities
Support information with APA compliant in-text citations in your slide, and then make sure to include the full reference for the citation in the List of References slide (last slide of this presentation)
2
Literature Review: Problem Space
10/9/2019
Perception plays a very important role in motivating learners
It is build on the foundation of the dynamics of instructor-student relationship hence role ...
Infectious diseases projectThis project is PowerPoint, or a paLizbethQuinonez813
Infectious diseases project
This project is PowerPoint, or a paper and is the mandatory 10% LIRN.
1- Guidelines for the Project: It could be either a PPT or a paper academic style
- Include name of the disease and student(s) name
- The paper must have academic style (you pick it)
- The PPT must have a minimum of 8 slides, do not type many lines in one slide make it easy to follow, add photos.
Either for the PPT or the paper, this work should have all of the following aspects about your disease: (Write each topic in the order given)
· Name the infectious disease.
· Mention the organism(s) that cause the disease.
· Pick the most common organism that causes the disease and tell about the organism: Classification of the organism, organism’s habitat, general characteristics and virulence factors of the organism (Include pictures of the microorganism (bacteria, virus, helminth).
· About the disease:
· Write how is the disease transmitted, what is the portal(s) of entry and, where does it cause problems in humans’ body (what organs or system(s) are affected.
· Signs and symptoms (include pictures of them).
· Diagnosis and Treatment.
· Prevention.
· Epidemiology: Include cases in U.S. and/or where is mostly present, who gets affected (kids, women, men, all), and it there are cases of nosocomial infections or not and why.
· References
WHOEVER HAS NOT PICKED UP A TOPIC NEEDS TO SEND ME AN EMAIL WITH THE TOPIC YOU CHOSE.
The style for the PPT or paper you decide it, just do it academically acceptable and interesting.
Due Date: 10/24/2021
Project assignments
Bacteria
Topic
Student
Paper
Presentation/PPT
1
Viral lung infections
Maylin, Eddy
Picked
2
Tuberculosis
3
folliculitis
4
Streptococcal skin diseases
5
Conjuctivitis
6
Trachoma and STD by C. trachomatis
7
Botulism
8
Meningitis
9
Tetanus
Enny
Picked
10
Peptic ulcers
11
Foodborne infections: Salmonellosis,
12
Amebiasis, or Taenia
13
Upper UTI’s
14
Lower UTI’s
15
HPV
16
Bacterial vaginosis
17
Gonorrhea
18
HSV-1, HSV-2
19
Syphilis
20
Sepsis
21
Zyca
22
Malaria
23
Endocarditis
24
Chikungunya
25
Yellow fever, or dengue
26
HIV,
27
Mononucleosis
28
Ebola,
29
Rabies
30
Prions
31
African sleeping sickness
32
Hepatitis
33
Lyme disease
34
COVID19
35
C. dif
36
Assignment: Psychotherapy for Clients With Addictive Disorders
Addictive disorders can be particularly challenging for clients. Not only do these disorders typically interfere with a client’s ability to function in daily life, but they also often manifest as negative and sometimes criminal behaviors. Sometime clients with addictive disorders also suffer from other mental health issues, creating even greater struggles for them to overcome. In your role, you have the opportunity to help clients address their addictions and improve outcomes for both the clients and their families.
To prepare:
· Review this week’s Learning Re ...
Individual Project You are a business analyst in a publicly-trLizbethQuinonez813
Individual Project You are a business analyst in a publicly-traded company. Your team is working with
stakeholders regarding options for expansion. The company must decide at least two possible countries
for expansion based on specific criteria. Your job is to present a report to identify the following
information. First, you will identify the countries where this company is currently operating. Next, you
will identify and then analyze at least two possible countries for expansion based on specific criteria
using a minimum of 10 distinct class concepts, such as: Formal and informal institutions in those
countries International trade and trade barriers Whether FDI is attractive or unattractive Foreign
exchange opportunities/issues Whether regional integration is present and how this may impact
expansion Possible modes of entry with recommendations Discuss marketing/HR items of note to
successfully operate in the new country The report should contain a minimum of 1,500 words, excluding
cover page/references section, and should follow the most current edition of APA formatting. The
report should contain a minimum of five citations to at least five distinct references used. You must
provide a reference list at the end of the report in addition to including in-text citations in the body of
the report to identify where resources are used. Instructors determine the due date for this project
during the week it is assigned. In the alternative, this assignment may be given as a group project as
determined by the instructor. Individual project is worth 250 points. It is due to the appropriate Dropbox
in Week 8.
...
Individual Differences
Self-Awareness and Working with Others
Dr.Nathanson
1
1
Individual Differences at Work
We seek to understand people in order to develop insight into our own behavior, and the behavior of others, and to respond in effective ways in work settings.
Insight
Effective Interactions
*
PersonalityWho are you, and why do you behave the way that you do?the combination of stable physical and mental characteristics that give an individual his or her identitystable over time, stable across situationsunique set of complex, interacting characteristics“Habits of Response”
*
Personality (cont.)Origins of personality?genetics (nature)early life experience (nurture)modeling, reinforcement, stability of context, family dynamicsImpact of personality at work?Person x Situation interactionorganizations are “strong situations”dependent on culture, job, group factors
*
Personality (cont.)“Big Five” Personality Dimensionsdecades of research and theoretical discussions of personality --> dozens of personality dimensions1970’s and 1980’s: statistical methods (e.g., factor analysis) provided a “clearer picture”conscientiousness, extroversion, openness to experience, neuroticism, agreeablenessonly moderate predictors
*
Group exerciseEach group member should discuss their profile, i.e are they high or low or in the middle for each of the Big 5 elements.
Then the group should discuss on average what the group personality is like.
Select a group leader and report to the class.
*
Personality (cont.)Locus of Controlan individual’s sense of control over his/her life, the environment, and external eventsHigh Internal LOCtask-oriented, innovative, proactive, self-confidentHigh External LOCsensitive to social cues, anxious changes with strong situational cues
*
Personality (cont.)Tolerance for Ambiguityextent to which individuals are threatened by or have difficulty coping with ambiguity, uncertainty, unpredictability, complexity…High Tolerance for Ambiguitycan handle more informationbetter at transmitting informationmore adaptivesensitive to other’s characteristics
*
Personality (cont.)Do organizations have personalities?SAS TheoryB. Schneiderthrough the combined processes of selection, attrition, and socialization, organizations create a culture with a “stable personality”implications?
*
Emotionscomplex, patterned, organismic reactions to how we think we are doing in our efforts to survive and flourish; goal orientedbiological, psychological, socialgoal oriented: related to our ability to achieve what we wantnegative emotions: triggered by frustration (anger, jealousy)positive emotions: triggered by attainment (pride, happiness)
*
Emotional IntelligencePredictive of “star performance”: who does well, who gets aheadDaniel Goleman: Working with Emotional Intelligencebased on research in 500+ organizationsmore important in predicting success than technical skills or IQHigh “EQ”: works well ...
Individual Project I-21. TitleTechnology Management Plan LizbethQuinonez813
Individual Project I-2
1. Title
Technology Management Plan
2. Introduction
You have been selected to be the acting CIO for a subsidiary of Largo Corporation called Rustic Americana. Its primary products include arts and crafts that reflect the history, geography, folklore and cultural heritage of the United States. It specializes in direct marketing and sales through its call center. Sales are through a web store, a brick and mortar store, and a direct mail catalogue. All services are housed under one roof that include warehousing, order fulfillment, shipping, corporate management and operations, and the call center. The success of the company hinges on its eye-catching direct mail catalogue and the unique product line.
Unfortunately, annual sales have declined over the years due largely due to internal issues. The previous CIO was terminated some say due to incompetence primarily related to the underperforming call center. In addition, speculation swirled around the activities of the CIO. He was often absent from the building. He secluded himself behind the closed door of his office. Associated rumors mounted, and it was believed that he was running a consulting business on company time. When the Rustic Americana CEO asked him about this during a formal review, the CIO answered that it was a weekend hobby that kept him abreast of emerging technologies. The CEO asked him if one of their competitors was a client and he vehemently denied the accusation. She was certain that the CIO was not being entirely truthful with her.
Call Center Operations
Managing a call center demands a wide range of skills including managerial, troubleshooting, patience and being cool under pressure. Knowledge of computer and communications skills is helpful but most call centers have a technical support division. The call center manager is Prisha Khan – she has been in the job for about 2 months.
The customer service representative (CSR) in the call center responds to a call for product. On the customer management system (CMS), the CSR collects and directly enters customer information; on a separate inventory management system (IMS), the CSR looks up the product, and verifies if the warehouse has it in stock. If it does, the order is entered on the CMS, and the CSR decreases the inventory on the IMS. On the CMS, the CSR creates an order fulfillment ticket that is automatically shuttled to the warehouse processing clerk who prints it and then generates the shipping label. The shipping label is prepared through a web-based system through either UPS or USPS, which also produces a tracking number used by both the company and the customer. The processing clerk enters the shipping costs and tracking number into the CMS. The customer is billed when the order ships.
The warehouse crew uses bar code scanners to track merchandise; once the order is selected, it moves along a conveyor to a shipping clerk who packages the order, affixes the shipping label, sca ...
Individual Case Study – ChipotleBUSI 690 – Policy and StraLizbethQuinonez813
Individual Case Study – Chipotle
BUSI 690 – Policy and Strategy in Global Competition
1
CHIPOTLE
Individual Case Study – Chipotle
Executive Summary
Chipotle Mexican Grill, Inc. is one of the leading quick-service restaurant chains in the US and
operates 2,622 restaurants. The company’s existing strategy and business model indicate that it
operates firm-owned restaurants and focuses on delivering high-quality food at low prices
everyday to customers. The company has been successful but faces numerous complaints
regarding food contamination. This report presents a new mission statement appropriate for its
businesses and carries an internal analysis of the company. Based on the internal and financial
analysis, two alternative strategies have been proposed, and projections based on the
recommended strategy to open up new casual dining restaurants in the US are presented in this
report. It is suggested that the new strategy will increase the company’s profitability and generate
a positive net present value.
Existing Mission, Objectives, and Strategies
The company’s existing mission is “food with integrity” [CITATION Chi201 \l 1033 ] which
implies that it ensures that its supplies are from sustainable sources without the use of chemicals
that could have harmful effects on humans. The primary goal of the company is to “focus on safe
and delicious food made with better ingredients” [CITATION Chi202 \l 1033 ]. Its strategy
remained to have a small menu that offers limited choices of healthy, nutritious, and good quality
food items at competitively low prices. Furthermore, its focus is on expanding the network on its
restaurants in the United States until recently, as the company has launched its online and mobile
food ordering systems. It relies on providing efficient customer service and carrying out strong
advertising and marketing programs to communicate with customers and increase its sales.
2
CHIPOTLE
A New Mission Statement
The new mission statement of Chipotle is to (1) serve customers (2) healthy and delicious food
(3) without boundaries (4) by using sustainable food production technologies (5) and consistently
growing its business (6) by expanding its network and following ethical practices (7) and
challenging its competitors (8) by giving best quality food and value and services (9) by its
highly trained employees.
Analysis Of the Firm’s Existing Business Model
The existing business model of Chipotle focuses on providing enhanced food experience to its
customers. The key to the company’s business model is that it was not based on the standards of
Quick Service Restaurants (QSR) and offered a new approach to the business that challenged
other companies in the market. The company operates a large network of more than two
thousand restaurants in the United States and thirty restaurants in internal markets. Its business
model is based on a simple menu with a limited number of ...
Individual Assignment 3: ***Signature Assignment Recommendations for increasing value, creativity and innovation in a specific company.
Due Week 7 (Sunday night midnight)
Value 300 points
Length: 12-15 pages (page count does not include appendices, title page, visual display or references).
With Signature Assignments that are due on Week 7 all students must turn in their papers at the due date and no late papers will be graded for points, as the term is over, and students and faculty must prepare for the next term.
Be sure you include information from the Isaksen and Magretta text books and cite using APA. Citations should be short. The citations from both books must be direct applications from the text. This means that you do not use the textbook to define concepts like (creativity, innovation, creative problem solving) but you use the textbook to apply what you have learned. Remember using the textbooks to define concepts is undergraduate work.
Note: This final assignment is worth approximately ⅓ of your grade. Be very careful to follow the Rubric and the instructions below. In this paper students are to show mastery of all that they have learned through application of those concepts from this class into this final assignment. Review the Course Learning Outcomes found below as great papers will give indications that learning has occurred in each of the following six categories :
1. Examine existing personal creativity skills and cultivate additional personal creativity skills in both personal and professional settings.
2. Analyze the connection between creativity, leadership and bringing value and solving problems within the workplace.
3. Analyze the need for increasing creative thought in a complex global environment including designing strategies to increase cash, profit and growth through understanding competitive dynamics.
4. Identify the various business segments and the different or similar ways that each segment drives for profitability through creativity and resultant innovation.
5. Analyze and apply decision matrices especially Michael Porter’s work for creative opportunities, or to mitigate risk and/or legal considerations in the global marketplace including compliance with Foreign Corrupt Practices Act (FCPA).
6. Develop collaborative processes across stakeholders, including customers and suppliers to increase creativity and innovation.
Students will begin this final paper by reviewing the comments and suggestions from their instructor from Assignment 2, which was the outline for many issues addressed in this final paper. The instructor will review Assignment 2 before grading Assignment 3 to be sure that all suggestions from that paper have been incorporated into the final paper.
This paper will follow all APA guidelines and will be: Double Spaced, Times New Roman, APA Headings, Title Page, References and APA citations. This is an example of an APA sample paper. Long quotes are not to be used in this paper, thus, all quote ...
Individual Care Map Evaluation Tool – NSG240315430Name ____LizbethQuinonez813
Individual Care Map Evaluation Tool – NSG240/315/430
Name: _______________________ Date: ___________ Patient’s initials: _______________
Concept
240/315/430
(Follow instructions provided and on Moodle)
The student will:
Maxi-mum Points/
Prepare: Written Analysis and Concept Map
Student points
Unsatisfactory
Basic
Satisfactory
Exceeds expectations
Comments:
Conduct and describe a thorough history and physical (Medical diagnosis, Lab and diagnostic tests, physician's orders)
History and physical with many errors and components not addressed. (2 pts)
Partially conducts and describes history and physical with <80% accuracy. (5 pts)
Conducts and describes thorough history and physical. All components complete. (8 pts)
Conducts and describes thorough history and physical. All components complete and individualized to patient. (10 pts)
Prepare: a table describing the pharmacotherapies: Medication, dose, frequency, route, class, top 3 side effects, indications
Table of pharmacologic interventions with many errors of omission and content accuracy. (2 pts)
Prepares a partially complete table of pharmacologic interventions with <80% accurate content. (5 pts)
Prepares a complete and accurate table of pharmacologic interventions. (8 pts)
Prepares a complete and accurate table of pharmacologic interventions. Indications are individualized for the patient.(10 pts)
Demonstrate appropriate use of Gordon's Functional Patterns (GP) by organizing data into meaningful data clusters to determine associated nursing diagnosis (NDx).
Data disorganized; GP not identified or not with appropriate data clusters; NDx do not reflect understanding of client problems. (1 pt)
60-80% of data organized and clustered; <80% of GP supported; NDx partially reflects understanding of client needs. (2 pts)
80-90% of data organized and clustered; 80-90% of GP identified with supportive data clusters; NDx identified reflect understanding of client problems. (4 pts)
All data organized and clustered to represent 100% of Gordon's functional patterns; associated NDx identified reflect understanding of client problems. (5 pts)
List at least 3 Nursing Diagnoses (NDx) based upon analysis of the data (must have at least 1 actual physiological, 1 psychosocial, and 1 educational nursing diagnosis clearly identified). All identified NDx listed from highest priority to lowest priority.
Does not have required number or types of NDx; NDx not written in correct format; NDx not listed from highest to lowest priority. (2 pts)
≤ 3 NDx listed based upon analysis of the data; does not include at least 1 actual physiological, 1 psychosocial, and 1 educational NDx; < 80% of NDx statements reflect correct formatting; <80% identified NDx listed from highest priority to lowest priority. (5 pts)
3 NDx listed based upon analysis of the data; includes at least 1 actual physiological, 1 psychosocial, and 1 educational NDx; All parts of the NDx st ...
Individual Assignment 2 Research, Analysis & Outline for Final PaLizbethQuinonez813
Individual Assignment 2: Research, Analysis & Outline for Final Paper
CLO #3 Analyze the need for increasing creative thought in a complex global environment including designing strategies to increase cash, profit and growth through understanding competitive dynamics.
CLO#5 Analyze and apply decision matrices for creative opportunities, or to mitigate risk and/or legal considerations in the global marketplace including compliance with Foreign Corrupt Practices Act (FCPA).
Due:Wednesday Week 6
Value: 150
Length: 5 - 7 page informal outline.
The purpose of this assignment is for students to write an outline that presents their research for the final paper (the Signature Assignment) for this class. Students are not writing the final paper (yet). For this assignment, and thus for the final paper students are to identify a business that corresponds to the assigned business sectors (each student is to identify a separate business). In this outline, students will bring options and opportunities, creative problem solving to either solve a problem or create an opportunity. Remember we do not tell companies what they “must or should do.” We present options and opportunities. Students will apply creative innovative thought to the analysis. You can use bullet points for this outline. Students should apply any feedback received from this assignment to the final assignment.
Some important items to note before writing Assignment 2:
· Please go to Week 8 and read the Handout and Rubric for Assignment 3.
· The research is very detailed, double-spaced, Times New Roman, APA Headings, Title Page, References and APA citations. This is an example of an APA sample paper.
· Long quotes are not to be used in short papers of this nature; thus, all quotes should be from seven to 12 words and of course must use APA citations.
· The outline is to detail key points supported with corresponding citations.
· The outline must use at least three levels of Use APA headings. Sources (must be current - one year) other than the textbook can include: New York Times, Wall Street Journal, Harvard Business Review, Wired Magazine, (all can be found in the our University Library). You can also use any government website (usually “.gov”). You can use academic research but it must be recent (five years or newer).
Directions
After reading assigned chapters in your textbook and other course materials, continue your research to gain additional knowledge on industries and business sectors. This following link, located here, has access to a breakdown of all industries. The links after each industry provides additional data.
For the outline, briefly describe the business that you have chosen and the global footprint of their broader industry [e.g. number of subsidiaries in other countries, information on profit and growth strategies, key suppliers and customers. List three (3) major competitors (supported by data), and explain the percentage of the market share the business occup ...
Individual Assignment - Nike Case Write-Up Mergers & AcquisiLizbethQuinonez813
Individual Assignment - Nike Case Write-Up
Mergers & Acquisitions
Introduction (Objective of the Assignment)
The Nike Case Study is intended to serve as an introduction to the calculation of the Weighted-
Average Cost of Capital (WACC) of the firm.
The case provides a WACC calculation that contains errors based on conceptual
misunderstandings. Students will identify and explain the mistakes in the analysis. The case
assumes that students have been exposed to the WACC, CAPM, the dividend discount model,
and the earnings capitalization model.
Assignment Requirements
Complete the Nike Case Study reading (found in the Readings and Course Materials folder).
Put yourself in the role of one of the stakeholders in the case and reflect on the information in
the document. Make sure to address the following items:
1. What is the WACC and why is it important to estimate a firm’s cost of capital? [2 to 3
sentences max.]
2. Calculate your own WACC for Nike. Note the following requirements:
a. Calculate the Cost of Debt based on the information provided in the case. [Fill in
the highlighted Excel cells; explain your calculation briefly]
b. When you are calculating the Cost of Equity, do it under three different
scenarios:
i. CAPM [Fill in Excel file]
ii. Dividend Discount Model [Fill in Excel file]
iii. Earnings Capitalization method [Fill in Excel file]
c. Summarize what the WACC would be in 3 different scenarios: using the Cost of
Debt and three different Cost of Equity percentages.
3. Highlight/note any differences versus Joanna Cohen’s calculation.
4. Which of your three WACC calculations (based on the 3 different Costs of Equity) do
you think makes the most sense and why?
You should have the following section in your final submission. They should look something like
this:
1. What is your WACC and Why is it Important?
Your answer…
2. WACC Calculations
A Summary of your findings. You will submit the Excel file separately.
3. Differences vs. Joanna Cohen
Your answer…
4. WACC Recommendation
Your answer….
Assignment Format
Students will submit the filled out provided Excel file (answering the highlighted cells), and their
write-up by the due date. The write-up should be brief and organized to answer the questions
listed in section II. It should be 2 pages maximum, double-spaced, with Calibri (12 pt). This
assignment should also have a cover page with:
• Your name
• The course number/name
• Your instructor’s name
Rubric
This is an individual assignment and accounts for 5% of your overall grade. You will be
assessed according to the following rubric.
Superior
High
Quality
Average Below
Average
Poor
Formatting and Creativity - Student
correctly incorporates all formatting
requirements. Student identifies a role in
the case and analyzes the case from that
perspective; i.e. the student “owns” the
case.
10 – 9 pts 8 ...
Individual Case InstructionsYou will identify a problem that reqLizbethQuinonez813
Mark volunteered to help with a community arts festival. However, his good intentions backfired when the retail store's phone number he provided was printed incorrectly in festival advertisements, overloading phone lines and annoying the store manager. As a result, Mark lost his job as assistant manager, even though he had only meant to support the not-for-profit organization. The Board of Directors did not investigate when Mark requested one, leaving him without work and wondering what went wrong when he tried to do a good deed.
In-Depth Integrative Case 4.1 How Didi Fought Uber in China LizbethQuinonez813
In-Depth Integrative Case 4.1
How Didi Fought Uber in China and Won; Next, Taking On the
World
Introduction
Technology is constantly evolving, and firms who have leveraged the unprecedented growth
rate of modern innovation have seen quick success. Didi Chuxing, China’s largest ridesharing
servicer, is no exception. With roots dating back to 2012, Didi has quickly gained Chinese
support, and with over 7.4 billion rides completed in 2017, Didi’s emphasis on technology has
allowed the young ridesharing firm to gain monopolistic authority within China.1
Rising transportation demand in China has created intense ridesharing competition within
China, and Didi’s early expansion efforts were obstructed by competitors, most notably Uber,
who entered China in 2014. With locations in over 60 countries, Uber had the experience
needed to quickly gain a foothold within China. Hefty subsidies, discounts, and marketing
promotions propelled the competitive battle between Uber and Didi, and the immediate
influence of Uber’s reputation led to a quick deterioration of Didi’s market dominance.
Nonetheless, governmental protectionism, strong Chinese partners, and a unique cultural
landscape in China presented Didi with the competitive edge needed to halt Uber’s expansion.2
Fierce opposition weakened revenues, and each firm reported losses exceeding US$1 billion
within the first year of competition.3 As a result, in August of 2016, Uber and Didi agreed to
US$35 billion alliance in which Didi would acquire Uber China. In return, Uber would receive an
initial 5.89 percent stake in the combined company, and with preferred equity interest, Uber’s
total position amounted to 17.7 percent.4 This announcement effectively halted Uber’s effort
to compete head-on with Didi in China and confirmed Didi’s dominance over the Chinese
ridesharing market.
The acquisition of Uber China meant only temporary peace to cut throat ridesharing
competition, and new wars are beginning to emerge as the two firms each strive to gain global
ridesharing dominance. Uber is now faced with a difficult situation as Chinese authority and
growing revenue streams inch Didi closer to global superiority. As Didi prepares to expand into
international markets, it is only a matter of time before these two players clash once again.5
An Evolving Chinese Ridesharing Market
China has quickly become the world’s largest provider of ridesharing services, and in 2017, a
total of 20.81 billion rides were offered through these platforms. Today, ridesharing accounts
for almost 2 percent of all transportation within China.6 While ridesharing may retain only a
modest presence, it is nonetheless the fastest growing method of transportation in the nation
as these services have been available for less than a decade. Rapid growth justifies China’s
US$30 billion ride hailing market valuation, and continued development has led analysts to
believe that this market will double in ...
In this reflection, introduce your professor to your project. Speak .docxLizbethQuinonez813
In this reflection, introduce your professor to your project. Speak about the pro and con sides of the controversy, and present your thesis statement. Then, consider some of the following questions as you reflect upon the road so far. If you want to, explain a little bit about your process. What have you experienced so far in writing your paper? Was it difficult or fairly easy to come up with your design? Do you feel confident about your progress so far? How do you feel about your thesis statement? What would you like to do in revisions? What step seems the most difficult or the easiest for you?
Your response should be at least 200 words. No references or citations are necessary.
.
In this discussion, please address the followingDiscuss how oft.docxLizbethQuinonez813
A project schedule should be reviewed regularly, such as weekly, by the project manager and team to track progress and make adjustments if needed. While the project manager and team should review the schedule primarily, it can also be beneficial to get input from other stakeholders. Creating a project schedule has advantages like helping define deliverables, estimate resources and time needed, and coordinate tasks. However, schedules also require ongoing maintenance and updates as the project evolves.
In this course, we have introduced and assessed many noteworthy figu.docxLizbethQuinonez813
In this course, we have introduced and assessed many noteworthy figures related to the colonizing and first 90 years of the United States. For this assignment, you will choose a significant figure who contributed to and influenced others during the time discussed in this course—with the exception of any U.S. President—and prepare a tribute focusing on his or her relevance to today. This is not a biography. Your argument should highlight how society remembers your historical figure now, based on the philosophies and ideals he or she presented or helped to change and evolve.
The style of this project is a multimedia presentation with both audio and video components; however, the medium used is up to you. Potential examples include, but are not limited to, a videotaped speech, a self-guided PowerPoint presentation, or a video with audio. Creativity and effort will impact the final grade.
Projects are due during Unit VII and will be graded on the following:
Prepare and submit a two-page reflection, ideally based on the outline assignment from Unit VI.
Create and submit a visual presentation with your reflection as an audio transcript.
Use a minimum two sources that can be found in CSU’s Online Library (at least one from the American History & Life database).
Proper citations and references for any use or identification of those sources must be used.
Length must fall within three to five minutes; in the case of PowerPoint, slides and audio should progress and stop automatically like a taped presentation.
Content accuracy and avoidance of anachronism are a must.
.
In this Assignment, you will focus on Adaptive Leadership from a.docxLizbethQuinonez813
In this Assignment, you will focus on Adaptive Leadership from a global perspective. When approaching this Assignment, do so from an international and global view
PLEASE SEE ATTACHED RUBRIC AND FOLLOW AS DIRECTED
NOTE THE PROGRAM : TURNITIN WILL BE USED TO DETECT A CERTAIN PERCENTAGE OF ORGINALITY
.
Inferential Analysis
Chapter 20
NUR 6812Nursing Research
Florida National University
Introduction - Inferential Analysis
We will discuss analysis of variance and regression, which are technically part of the same family of statistics known as the general linear method but are used to achieve different analytical goals
ANALYSIS OF VARIANCE
Analysis of variance (ANOVA) is used so often that Iversen and Norpoth (1987) said they once had a student who thought this was the name of an Italian statistician.
You can think of analysis of variance as a whole family of procedures beginning with the simple and frequently used t-test and becoming quite complicated with the use of multiple dependent variables (MANOVA, to be explained later in this chapter) and covariates.
Although the simpler varieties of these statistics can actually be calculated by hand, it is assumed that you will use a statistical software package for your calculations.
If you want to see how these calculations are done, you could try to compute a correlation, chi-square, t-test, or ANOVA yourself (see Yuker, 1958; Field, 2009), but in general it is too time consuming and too subject to human error to do these by hand.
IMPORTANT TERMINOLOGY
Several terms are used in these analyses that you need to be familiar with to understand the analyses themselves and the results. Many will already be familiar to you.
Statistical significance: This indicates the probability that the differences found are a result of error, not the treatment. Stated in terms of the P value, the convention is to accept either a 1% (P ≤ 0.01), or 1 out of 100, or 5% (P ≤ 0.05), or 5 out of 100, possibility that any differences seen could have been due to error (Cortina & Dunlap, 2007).
Research hypothesis: A research hypothesis is a declarative statement of the expected relationship between the dependent and independent variable(s).
Null hypothesis: The null hypothesis, based on the research hypothesis, states that the predicted relationships will not be found or that those found could have occurred by chance, meaning the difference will not be statistically significant.
Effect size: This is defined by Cortina and Dunlap as “the amount of variance in one variable accounted for by another in the sample at hand” (2007, p. 231). Effect size estimates are helpful adjuncts to significance testing. An important limitation, however, is that they are heavily influenced by the type of treatment or manipulation that occurred and the measures that are used.
Confidence intervals: Although sometimes suggested as an adjunct or replacement for the significance level, confidence intervals are determined in part by the alpha (significance level) (Cortina & Dunlap, 2007). Likened to a margin of error, the confidence intervals indicate the range within which the true difference between means may lie. A narrow confidence interval implies high precision; we can specify believable values within a narrow range ...
Infancy to Early Childhood Case AnalysisPart IFor this diLizbethQuinonez813
Infancy to Early Childhood Case Analysis
Part I:
For this discussion board assignment, you will conduct an interview with a parent who has a child in the early childhood stage of development. In your interview, solicit information to understand the child's development from infancy to early childhood about the area of development assigned to you.
--please explore the social needs of the child's development.
Social Needs: For social needs, use Erikson's psychosocial theory of development.
ALL students should also explore how multi-cultural factors have impacted the area of development you are exploring (i.e., ethnicity, race, gender, socioeconomic status, ableism, religion, sexual orientation and other sub-cultural influences such as military). There are two optional videos in the learning module that will help you think about culture more deeply and generate ideas about possible areas/questions to explore with your interviewee.
Quality posts will integrate material from the textbook to support your analysis of the child's development. All material from the textbook should be cited in APA style. Students should define psychological terms and concepts used; assume your audience is not familiar with developmental psychology.
...
Infectious Diseases
Name
Course
Instructor
Date
Introduction
Infectious infections have created increased attention.
Covid-19 is the most recent challenges caused by infectious diseases.
https://idpjournal.biomedcentral.com/
Introduction
Infectious infections have created increased attention, especially after several outbreaks and pandemics that altered human health globally. Covid-19 and the related infections are the most recent challenges caused by infectious diseases affecting the whole world. This presentation illustrates common infectious diseases in the nature they are caused, their diagnosis, treatment, and possible prevention methods. It shall also describe the common symptoms of infectious diseases and when to seek medical attention.
2
Overview
Overview
Infectious diseases have attracted increased attention globally because of their various occurrence. Its symptoms range from mild to severe, and the treatment and management depend on the cause of infection. Infectious diseases are caused by several pathogens, such as bacteria, viruses, parasites, and fungi, to mention a few. Transmission of pathogens in humans happens in numerous ways, including direct transmission through contact, water, and foodborne infections. Infection from insects such as ticks and mosquitoes can also effectively transmit pathogens.
3
Infectious diseases have numerous occurrences.
Symptoms range from mild to severe.
Pathogens include bacteria, viruses, parasites, and fungi.
Transmission include through contact, water and food, and insects.
Individuals with a higher risk of infectious diseases
All individuals are at risk of contracting infectious diseases.
Individuals with compromised immune systems are at higher risk.
They include;
People with suppressed immunities.
People unvaccinated for certain infectious diseases
Children and healthcare workers.
https://www.youtube.com/watch?v=9axOFtPqS0c
Individuals with a higher risk of infectious diseases
All individuals are at risk of contracting infectious diseases. However, individuals with compromised immune systems are at higher risk of getting infectious diseases. Individuals at higher risks of getting infectious diseases include; people with suppressed immunities, such as patients of cancer, HIV, and recent organ transmissions. People unvaccinated for certain infectious diseases are also considered at higher risk of getting infectious diseases. Other individuals at higher risks of getting infectious diseases are children and healthcare workers.
4
How Common are infectious diseases?
How Common are infectious diseases?
Infectious diseases are common worldwide. Some infectious diseases are more common and strike more often than others. For instance, infections caused by E. coli are common and may not require medications because they may cause mild signs of complications. In the United States, a fifth of the population is infected with influenza annually. This indicates that infectiou ...
Individual Focused Learning for Better Memory Retention Through LizbethQuinonez813
Individual Focused Learning for Better Memory Retention Through Experience
CONFIDENTIAL
GCU – For Internal Use Only
1
Literature Review: Background to the Problem
10/9/2019
Cognitive theory focuses on experiences in three looping processes, comprehension, memory, and application
According to Goossens (2020), cognitive theories in learning is affected by biology, environment, and social constructs
Bottom-up and top-down influences define experience of learning and thus memory and its retention (Tyng et al., 2017)
Comprehension is interpretative with different people and methodologies of gaining skills require support for better retention of knowledge (Ford et al., 2020)
CONFIDENTIAL
GCU – For Internal Use Only
Objective:
The outline on this slide is used in the Prospectus to develop the Background of the Study in Chapter 1 and the Background of the Problem Space in Chapter 2.
Slide Requirements:
Use either a bulleted format or table format
Describe what is already understood about the problem - Historically, memory retention is dependent on biology, social determinants, and educational roles (Berger et al., 2012)
Present findings from prior research related to the history of the problem space – individual are unique by circumstances, cognition development is different for each person hence memory retention and its experiences are unique. In education sector today, curriculum caters to meeting outcomes of the larger group with less focus on individual pace of learning.
Focus on:
When the problem started – generalization of education and learning environment through general curriculum tends to segregate some learners
What has been discovered about the problem - According to Tyng et al. (2017), “the effects of emotion on learning and memory are not always univalent” it points to the fact that progression is a personal journey such that how learning is understood is directly linked to how it is taught, the environment it is taught in, and the emotional attachments of information processing. Therefore, productivity in learning can only be attained by training and task definition which can be versatile form one person to another.
The current state of the problem – Development of separate special classes for students with learning challenge is beneficial but with poor education systems, the program could be detrimental for the future especially in self teaching learners. With guidance for retention of knowledge being a taught skill, ineffective environments and lack of support could be detrimental especially to disadvantaged communities
Support information with APA compliant in-text citations in your slide, and then make sure to include the full reference for the citation in the List of References slide (last slide of this presentation)
2
Literature Review: Problem Space
10/9/2019
Perception plays a very important role in motivating learners
It is build on the foundation of the dynamics of instructor-student relationship hence role ...
Infectious diseases projectThis project is PowerPoint, or a paLizbethQuinonez813
Infectious diseases project
This project is PowerPoint, or a paper and is the mandatory 10% LIRN.
1- Guidelines for the Project: It could be either a PPT or a paper academic style
- Include name of the disease and student(s) name
- The paper must have academic style (you pick it)
- The PPT must have a minimum of 8 slides, do not type many lines in one slide make it easy to follow, add photos.
Either for the PPT or the paper, this work should have all of the following aspects about your disease: (Write each topic in the order given)
· Name the infectious disease.
· Mention the organism(s) that cause the disease.
· Pick the most common organism that causes the disease and tell about the organism: Classification of the organism, organism’s habitat, general characteristics and virulence factors of the organism (Include pictures of the microorganism (bacteria, virus, helminth).
· About the disease:
· Write how is the disease transmitted, what is the portal(s) of entry and, where does it cause problems in humans’ body (what organs or system(s) are affected.
· Signs and symptoms (include pictures of them).
· Diagnosis and Treatment.
· Prevention.
· Epidemiology: Include cases in U.S. and/or where is mostly present, who gets affected (kids, women, men, all), and it there are cases of nosocomial infections or not and why.
· References
WHOEVER HAS NOT PICKED UP A TOPIC NEEDS TO SEND ME AN EMAIL WITH THE TOPIC YOU CHOSE.
The style for the PPT or paper you decide it, just do it academically acceptable and interesting.
Due Date: 10/24/2021
Project assignments
Bacteria
Topic
Student
Paper
Presentation/PPT
1
Viral lung infections
Maylin, Eddy
Picked
2
Tuberculosis
3
folliculitis
4
Streptococcal skin diseases
5
Conjuctivitis
6
Trachoma and STD by C. trachomatis
7
Botulism
8
Meningitis
9
Tetanus
Enny
Picked
10
Peptic ulcers
11
Foodborne infections: Salmonellosis,
12
Amebiasis, or Taenia
13
Upper UTI’s
14
Lower UTI’s
15
HPV
16
Bacterial vaginosis
17
Gonorrhea
18
HSV-1, HSV-2
19
Syphilis
20
Sepsis
21
Zyca
22
Malaria
23
Endocarditis
24
Chikungunya
25
Yellow fever, or dengue
26
HIV,
27
Mononucleosis
28
Ebola,
29
Rabies
30
Prions
31
African sleeping sickness
32
Hepatitis
33
Lyme disease
34
COVID19
35
C. dif
36
Assignment: Psychotherapy for Clients With Addictive Disorders
Addictive disorders can be particularly challenging for clients. Not only do these disorders typically interfere with a client’s ability to function in daily life, but they also often manifest as negative and sometimes criminal behaviors. Sometime clients with addictive disorders also suffer from other mental health issues, creating even greater struggles for them to overcome. In your role, you have the opportunity to help clients address their addictions and improve outcomes for both the clients and their families.
To prepare:
· Review this week’s Learning Re ...
Individual Project You are a business analyst in a publicly-trLizbethQuinonez813
Individual Project You are a business analyst in a publicly-traded company. Your team is working with
stakeholders regarding options for expansion. The company must decide at least two possible countries
for expansion based on specific criteria. Your job is to present a report to identify the following
information. First, you will identify the countries where this company is currently operating. Next, you
will identify and then analyze at least two possible countries for expansion based on specific criteria
using a minimum of 10 distinct class concepts, such as: Formal and informal institutions in those
countries International trade and trade barriers Whether FDI is attractive or unattractive Foreign
exchange opportunities/issues Whether regional integration is present and how this may impact
expansion Possible modes of entry with recommendations Discuss marketing/HR items of note to
successfully operate in the new country The report should contain a minimum of 1,500 words, excluding
cover page/references section, and should follow the most current edition of APA formatting. The
report should contain a minimum of five citations to at least five distinct references used. You must
provide a reference list at the end of the report in addition to including in-text citations in the body of
the report to identify where resources are used. Instructors determine the due date for this project
during the week it is assigned. In the alternative, this assignment may be given as a group project as
determined by the instructor. Individual project is worth 250 points. It is due to the appropriate Dropbox
in Week 8.
...
Individual Differences
Self-Awareness and Working with Others
Dr.Nathanson
1
1
Individual Differences at Work
We seek to understand people in order to develop insight into our own behavior, and the behavior of others, and to respond in effective ways in work settings.
Insight
Effective Interactions
*
PersonalityWho are you, and why do you behave the way that you do?the combination of stable physical and mental characteristics that give an individual his or her identitystable over time, stable across situationsunique set of complex, interacting characteristics“Habits of Response”
*
Personality (cont.)Origins of personality?genetics (nature)early life experience (nurture)modeling, reinforcement, stability of context, family dynamicsImpact of personality at work?Person x Situation interactionorganizations are “strong situations”dependent on culture, job, group factors
*
Personality (cont.)“Big Five” Personality Dimensionsdecades of research and theoretical discussions of personality --> dozens of personality dimensions1970’s and 1980’s: statistical methods (e.g., factor analysis) provided a “clearer picture”conscientiousness, extroversion, openness to experience, neuroticism, agreeablenessonly moderate predictors
*
Group exerciseEach group member should discuss their profile, i.e are they high or low or in the middle for each of the Big 5 elements.
Then the group should discuss on average what the group personality is like.
Select a group leader and report to the class.
*
Personality (cont.)Locus of Controlan individual’s sense of control over his/her life, the environment, and external eventsHigh Internal LOCtask-oriented, innovative, proactive, self-confidentHigh External LOCsensitive to social cues, anxious changes with strong situational cues
*
Personality (cont.)Tolerance for Ambiguityextent to which individuals are threatened by or have difficulty coping with ambiguity, uncertainty, unpredictability, complexity…High Tolerance for Ambiguitycan handle more informationbetter at transmitting informationmore adaptivesensitive to other’s characteristics
*
Personality (cont.)Do organizations have personalities?SAS TheoryB. Schneiderthrough the combined processes of selection, attrition, and socialization, organizations create a culture with a “stable personality”implications?
*
Emotionscomplex, patterned, organismic reactions to how we think we are doing in our efforts to survive and flourish; goal orientedbiological, psychological, socialgoal oriented: related to our ability to achieve what we wantnegative emotions: triggered by frustration (anger, jealousy)positive emotions: triggered by attainment (pride, happiness)
*
Emotional IntelligencePredictive of “star performance”: who does well, who gets aheadDaniel Goleman: Working with Emotional Intelligencebased on research in 500+ organizationsmore important in predicting success than technical skills or IQHigh “EQ”: works well ...
Individual Project I-21. TitleTechnology Management Plan LizbethQuinonez813
Individual Project I-2
1. Title
Technology Management Plan
2. Introduction
You have been selected to be the acting CIO for a subsidiary of Largo Corporation called Rustic Americana. Its primary products include arts and crafts that reflect the history, geography, folklore and cultural heritage of the United States. It specializes in direct marketing and sales through its call center. Sales are through a web store, a brick and mortar store, and a direct mail catalogue. All services are housed under one roof that include warehousing, order fulfillment, shipping, corporate management and operations, and the call center. The success of the company hinges on its eye-catching direct mail catalogue and the unique product line.
Unfortunately, annual sales have declined over the years due largely due to internal issues. The previous CIO was terminated some say due to incompetence primarily related to the underperforming call center. In addition, speculation swirled around the activities of the CIO. He was often absent from the building. He secluded himself behind the closed door of his office. Associated rumors mounted, and it was believed that he was running a consulting business on company time. When the Rustic Americana CEO asked him about this during a formal review, the CIO answered that it was a weekend hobby that kept him abreast of emerging technologies. The CEO asked him if one of their competitors was a client and he vehemently denied the accusation. She was certain that the CIO was not being entirely truthful with her.
Call Center Operations
Managing a call center demands a wide range of skills including managerial, troubleshooting, patience and being cool under pressure. Knowledge of computer and communications skills is helpful but most call centers have a technical support division. The call center manager is Prisha Khan – she has been in the job for about 2 months.
The customer service representative (CSR) in the call center responds to a call for product. On the customer management system (CMS), the CSR collects and directly enters customer information; on a separate inventory management system (IMS), the CSR looks up the product, and verifies if the warehouse has it in stock. If it does, the order is entered on the CMS, and the CSR decreases the inventory on the IMS. On the CMS, the CSR creates an order fulfillment ticket that is automatically shuttled to the warehouse processing clerk who prints it and then generates the shipping label. The shipping label is prepared through a web-based system through either UPS or USPS, which also produces a tracking number used by both the company and the customer. The processing clerk enters the shipping costs and tracking number into the CMS. The customer is billed when the order ships.
The warehouse crew uses bar code scanners to track merchandise; once the order is selected, it moves along a conveyor to a shipping clerk who packages the order, affixes the shipping label, sca ...
Individual Case Study – ChipotleBUSI 690 – Policy and StraLizbethQuinonez813
Individual Case Study – Chipotle
BUSI 690 – Policy and Strategy in Global Competition
1
CHIPOTLE
Individual Case Study – Chipotle
Executive Summary
Chipotle Mexican Grill, Inc. is one of the leading quick-service restaurant chains in the US and
operates 2,622 restaurants. The company’s existing strategy and business model indicate that it
operates firm-owned restaurants and focuses on delivering high-quality food at low prices
everyday to customers. The company has been successful but faces numerous complaints
regarding food contamination. This report presents a new mission statement appropriate for its
businesses and carries an internal analysis of the company. Based on the internal and financial
analysis, two alternative strategies have been proposed, and projections based on the
recommended strategy to open up new casual dining restaurants in the US are presented in this
report. It is suggested that the new strategy will increase the company’s profitability and generate
a positive net present value.
Existing Mission, Objectives, and Strategies
The company’s existing mission is “food with integrity” [CITATION Chi201 \l 1033 ] which
implies that it ensures that its supplies are from sustainable sources without the use of chemicals
that could have harmful effects on humans. The primary goal of the company is to “focus on safe
and delicious food made with better ingredients” [CITATION Chi202 \l 1033 ]. Its strategy
remained to have a small menu that offers limited choices of healthy, nutritious, and good quality
food items at competitively low prices. Furthermore, its focus is on expanding the network on its
restaurants in the United States until recently, as the company has launched its online and mobile
food ordering systems. It relies on providing efficient customer service and carrying out strong
advertising and marketing programs to communicate with customers and increase its sales.
2
CHIPOTLE
A New Mission Statement
The new mission statement of Chipotle is to (1) serve customers (2) healthy and delicious food
(3) without boundaries (4) by using sustainable food production technologies (5) and consistently
growing its business (6) by expanding its network and following ethical practices (7) and
challenging its competitors (8) by giving best quality food and value and services (9) by its
highly trained employees.
Analysis Of the Firm’s Existing Business Model
The existing business model of Chipotle focuses on providing enhanced food experience to its
customers. The key to the company’s business model is that it was not based on the standards of
Quick Service Restaurants (QSR) and offered a new approach to the business that challenged
other companies in the market. The company operates a large network of more than two
thousand restaurants in the United States and thirty restaurants in internal markets. Its business
model is based on a simple menu with a limited number of ...
Individual Assignment 3: ***Signature Assignment Recommendations for increasing value, creativity and innovation in a specific company.
Due Week 7 (Sunday night midnight)
Value 300 points
Length: 12-15 pages (page count does not include appendices, title page, visual display or references).
With Signature Assignments that are due on Week 7 all students must turn in their papers at the due date and no late papers will be graded for points, as the term is over, and students and faculty must prepare for the next term.
Be sure you include information from the Isaksen and Magretta text books and cite using APA. Citations should be short. The citations from both books must be direct applications from the text. This means that you do not use the textbook to define concepts like (creativity, innovation, creative problem solving) but you use the textbook to apply what you have learned. Remember using the textbooks to define concepts is undergraduate work.
Note: This final assignment is worth approximately ⅓ of your grade. Be very careful to follow the Rubric and the instructions below. In this paper students are to show mastery of all that they have learned through application of those concepts from this class into this final assignment. Review the Course Learning Outcomes found below as great papers will give indications that learning has occurred in each of the following six categories :
1. Examine existing personal creativity skills and cultivate additional personal creativity skills in both personal and professional settings.
2. Analyze the connection between creativity, leadership and bringing value and solving problems within the workplace.
3. Analyze the need for increasing creative thought in a complex global environment including designing strategies to increase cash, profit and growth through understanding competitive dynamics.
4. Identify the various business segments and the different or similar ways that each segment drives for profitability through creativity and resultant innovation.
5. Analyze and apply decision matrices especially Michael Porter’s work for creative opportunities, or to mitigate risk and/or legal considerations in the global marketplace including compliance with Foreign Corrupt Practices Act (FCPA).
6. Develop collaborative processes across stakeholders, including customers and suppliers to increase creativity and innovation.
Students will begin this final paper by reviewing the comments and suggestions from their instructor from Assignment 2, which was the outline for many issues addressed in this final paper. The instructor will review Assignment 2 before grading Assignment 3 to be sure that all suggestions from that paper have been incorporated into the final paper.
This paper will follow all APA guidelines and will be: Double Spaced, Times New Roman, APA Headings, Title Page, References and APA citations. This is an example of an APA sample paper. Long quotes are not to be used in this paper, thus, all quote ...
Individual Care Map Evaluation Tool – NSG240315430Name ____LizbethQuinonez813
Individual Care Map Evaluation Tool – NSG240/315/430
Name: _______________________ Date: ___________ Patient’s initials: _______________
Concept
240/315/430
(Follow instructions provided and on Moodle)
The student will:
Maxi-mum Points/
Prepare: Written Analysis and Concept Map
Student points
Unsatisfactory
Basic
Satisfactory
Exceeds expectations
Comments:
Conduct and describe a thorough history and physical (Medical diagnosis, Lab and diagnostic tests, physician's orders)
History and physical with many errors and components not addressed. (2 pts)
Partially conducts and describes history and physical with <80% accuracy. (5 pts)
Conducts and describes thorough history and physical. All components complete. (8 pts)
Conducts and describes thorough history and physical. All components complete and individualized to patient. (10 pts)
Prepare: a table describing the pharmacotherapies: Medication, dose, frequency, route, class, top 3 side effects, indications
Table of pharmacologic interventions with many errors of omission and content accuracy. (2 pts)
Prepares a partially complete table of pharmacologic interventions with <80% accurate content. (5 pts)
Prepares a complete and accurate table of pharmacologic interventions. (8 pts)
Prepares a complete and accurate table of pharmacologic interventions. Indications are individualized for the patient.(10 pts)
Demonstrate appropriate use of Gordon's Functional Patterns (GP) by organizing data into meaningful data clusters to determine associated nursing diagnosis (NDx).
Data disorganized; GP not identified or not with appropriate data clusters; NDx do not reflect understanding of client problems. (1 pt)
60-80% of data organized and clustered; <80% of GP supported; NDx partially reflects understanding of client needs. (2 pts)
80-90% of data organized and clustered; 80-90% of GP identified with supportive data clusters; NDx identified reflect understanding of client problems. (4 pts)
All data organized and clustered to represent 100% of Gordon's functional patterns; associated NDx identified reflect understanding of client problems. (5 pts)
List at least 3 Nursing Diagnoses (NDx) based upon analysis of the data (must have at least 1 actual physiological, 1 psychosocial, and 1 educational nursing diagnosis clearly identified). All identified NDx listed from highest priority to lowest priority.
Does not have required number or types of NDx; NDx not written in correct format; NDx not listed from highest to lowest priority. (2 pts)
≤ 3 NDx listed based upon analysis of the data; does not include at least 1 actual physiological, 1 psychosocial, and 1 educational NDx; < 80% of NDx statements reflect correct formatting; <80% identified NDx listed from highest priority to lowest priority. (5 pts)
3 NDx listed based upon analysis of the data; includes at least 1 actual physiological, 1 psychosocial, and 1 educational NDx; All parts of the NDx st ...
Individual Assignment 2 Research, Analysis & Outline for Final PaLizbethQuinonez813
Individual Assignment 2: Research, Analysis & Outline for Final Paper
CLO #3 Analyze the need for increasing creative thought in a complex global environment including designing strategies to increase cash, profit and growth through understanding competitive dynamics.
CLO#5 Analyze and apply decision matrices for creative opportunities, or to mitigate risk and/or legal considerations in the global marketplace including compliance with Foreign Corrupt Practices Act (FCPA).
Due:Wednesday Week 6
Value: 150
Length: 5 - 7 page informal outline.
The purpose of this assignment is for students to write an outline that presents their research for the final paper (the Signature Assignment) for this class. Students are not writing the final paper (yet). For this assignment, and thus for the final paper students are to identify a business that corresponds to the assigned business sectors (each student is to identify a separate business). In this outline, students will bring options and opportunities, creative problem solving to either solve a problem or create an opportunity. Remember we do not tell companies what they “must or should do.” We present options and opportunities. Students will apply creative innovative thought to the analysis. You can use bullet points for this outline. Students should apply any feedback received from this assignment to the final assignment.
Some important items to note before writing Assignment 2:
· Please go to Week 8 and read the Handout and Rubric for Assignment 3.
· The research is very detailed, double-spaced, Times New Roman, APA Headings, Title Page, References and APA citations. This is an example of an APA sample paper.
· Long quotes are not to be used in short papers of this nature; thus, all quotes should be from seven to 12 words and of course must use APA citations.
· The outline is to detail key points supported with corresponding citations.
· The outline must use at least three levels of Use APA headings. Sources (must be current - one year) other than the textbook can include: New York Times, Wall Street Journal, Harvard Business Review, Wired Magazine, (all can be found in the our University Library). You can also use any government website (usually “.gov”). You can use academic research but it must be recent (five years or newer).
Directions
After reading assigned chapters in your textbook and other course materials, continue your research to gain additional knowledge on industries and business sectors. This following link, located here, has access to a breakdown of all industries. The links after each industry provides additional data.
For the outline, briefly describe the business that you have chosen and the global footprint of their broader industry [e.g. number of subsidiaries in other countries, information on profit and growth strategies, key suppliers and customers. List three (3) major competitors (supported by data), and explain the percentage of the market share the business occup ...
Individual Assignment - Nike Case Write-Up Mergers & AcquisiLizbethQuinonez813
Individual Assignment - Nike Case Write-Up
Mergers & Acquisitions
Introduction (Objective of the Assignment)
The Nike Case Study is intended to serve as an introduction to the calculation of the Weighted-
Average Cost of Capital (WACC) of the firm.
The case provides a WACC calculation that contains errors based on conceptual
misunderstandings. Students will identify and explain the mistakes in the analysis. The case
assumes that students have been exposed to the WACC, CAPM, the dividend discount model,
and the earnings capitalization model.
Assignment Requirements
Complete the Nike Case Study reading (found in the Readings and Course Materials folder).
Put yourself in the role of one of the stakeholders in the case and reflect on the information in
the document. Make sure to address the following items:
1. What is the WACC and why is it important to estimate a firm’s cost of capital? [2 to 3
sentences max.]
2. Calculate your own WACC for Nike. Note the following requirements:
a. Calculate the Cost of Debt based on the information provided in the case. [Fill in
the highlighted Excel cells; explain your calculation briefly]
b. When you are calculating the Cost of Equity, do it under three different
scenarios:
i. CAPM [Fill in Excel file]
ii. Dividend Discount Model [Fill in Excel file]
iii. Earnings Capitalization method [Fill in Excel file]
c. Summarize what the WACC would be in 3 different scenarios: using the Cost of
Debt and three different Cost of Equity percentages.
3. Highlight/note any differences versus Joanna Cohen’s calculation.
4. Which of your three WACC calculations (based on the 3 different Costs of Equity) do
you think makes the most sense and why?
You should have the following section in your final submission. They should look something like
this:
1. What is your WACC and Why is it Important?
Your answer…
2. WACC Calculations
A Summary of your findings. You will submit the Excel file separately.
3. Differences vs. Joanna Cohen
Your answer…
4. WACC Recommendation
Your answer….
Assignment Format
Students will submit the filled out provided Excel file (answering the highlighted cells), and their
write-up by the due date. The write-up should be brief and organized to answer the questions
listed in section II. It should be 2 pages maximum, double-spaced, with Calibri (12 pt). This
assignment should also have a cover page with:
• Your name
• The course number/name
• Your instructor’s name
Rubric
This is an individual assignment and accounts for 5% of your overall grade. You will be
assessed according to the following rubric.
Superior
High
Quality
Average Below
Average
Poor
Formatting and Creativity - Student
correctly incorporates all formatting
requirements. Student identifies a role in
the case and analyzes the case from that
perspective; i.e. the student “owns” the
case.
10 – 9 pts 8 ...
Individual Case InstructionsYou will identify a problem that reqLizbethQuinonez813
Mark volunteered to help with a community arts festival. However, his good intentions backfired when the retail store's phone number he provided was printed incorrectly in festival advertisements, overloading phone lines and annoying the store manager. As a result, Mark lost his job as assistant manager, even though he had only meant to support the not-for-profit organization. The Board of Directors did not investigate when Mark requested one, leaving him without work and wondering what went wrong when he tried to do a good deed.
In-Depth Integrative Case 4.1 How Didi Fought Uber in China LizbethQuinonez813
In-Depth Integrative Case 4.1
How Didi Fought Uber in China and Won; Next, Taking On the
World
Introduction
Technology is constantly evolving, and firms who have leveraged the unprecedented growth
rate of modern innovation have seen quick success. Didi Chuxing, China’s largest ridesharing
servicer, is no exception. With roots dating back to 2012, Didi has quickly gained Chinese
support, and with over 7.4 billion rides completed in 2017, Didi’s emphasis on technology has
allowed the young ridesharing firm to gain monopolistic authority within China.1
Rising transportation demand in China has created intense ridesharing competition within
China, and Didi’s early expansion efforts were obstructed by competitors, most notably Uber,
who entered China in 2014. With locations in over 60 countries, Uber had the experience
needed to quickly gain a foothold within China. Hefty subsidies, discounts, and marketing
promotions propelled the competitive battle between Uber and Didi, and the immediate
influence of Uber’s reputation led to a quick deterioration of Didi’s market dominance.
Nonetheless, governmental protectionism, strong Chinese partners, and a unique cultural
landscape in China presented Didi with the competitive edge needed to halt Uber’s expansion.2
Fierce opposition weakened revenues, and each firm reported losses exceeding US$1 billion
within the first year of competition.3 As a result, in August of 2016, Uber and Didi agreed to
US$35 billion alliance in which Didi would acquire Uber China. In return, Uber would receive an
initial 5.89 percent stake in the combined company, and with preferred equity interest, Uber’s
total position amounted to 17.7 percent.4 This announcement effectively halted Uber’s effort
to compete head-on with Didi in China and confirmed Didi’s dominance over the Chinese
ridesharing market.
The acquisition of Uber China meant only temporary peace to cut throat ridesharing
competition, and new wars are beginning to emerge as the two firms each strive to gain global
ridesharing dominance. Uber is now faced with a difficult situation as Chinese authority and
growing revenue streams inch Didi closer to global superiority. As Didi prepares to expand into
international markets, it is only a matter of time before these two players clash once again.5
An Evolving Chinese Ridesharing Market
China has quickly become the world’s largest provider of ridesharing services, and in 2017, a
total of 20.81 billion rides were offered through these platforms. Today, ridesharing accounts
for almost 2 percent of all transportation within China.6 While ridesharing may retain only a
modest presence, it is nonetheless the fastest growing method of transportation in the nation
as these services have been available for less than a decade. Rapid growth justifies China’s
US$30 billion ride hailing market valuation, and continued development has led analysts to
believe that this market will double in ...
In-Depth Integrative Case 4.1 How Didi Fought Uber in China
In-class student presentation assignmentEach presentation will l
1. In-class student presentation assignment
Each presentation will last from 5 to 10 minutes, during which
time, each student will be asked to read the title of their
research paper from the list of approved research paper topics
provided, read a statement of their pros and cons and summarize
their research paper’s conclusions. In the interest of time,
students will be required to omit the use of visual aids,
electronic or otherwise during the presentation. Rather than an
assignment centered around electronic displays of slides, graphs
and tables --typically presented in rapid succession, students
will be encouraged to think of themselves as “attorneys” or
“policy scientists” or “policy makers” making a final summation
of an argument before a jury of their peers or constituents
instead of an image of themselves making a typical video or
Power point presentation before a class of their peers. Not only
will such an approach place the emphasis on persuasion and
strength of argument, it will also eliminate technology and more
precisely any possible glitches in the technology occurring
during the course of the presentation, from unduly influencing
the student’s presentation grade.
Each student must also defend their research paper conclusions
and answer any questions raised by students and/or the
Instructor, at the time of the in-class presentation. No-shows
will receive the score of “0” for the assignments while late
presentations, if accepted, will receive a 40 point-late penalty.
Presentations will NOT be made after the “last-day-of-classes”
point in the semester. Students will be encouraged to take the
paper presentation deadline seriously and allowed and indeed
encouraged to complete the presentation before their scheduled
presentation date to avoid unforeseen circumstances that may
cause them to fail to present on time. The paper presentation
provides a total of 100 points and represents 25% of the
student’s final grade.
Frequent reminders of this important assignment will be made
2. by the Instructor throughout the course of the semester. Of
course, students with questions and/or concerns regarding the
paper presentation assignment are required to notify the
Instructor at the earliest possible time.
1
Effect of Self-efficacy and Depression on Quality of Life in
Outpatients with CHF
Ashmita Singh
College of Nursing and Health Innovation, The University of
Texas Arlington
NURS-3321: Nursing Research
Maxine Adegbola, PhD, CNE, RN, ANEF
October 2, 2021
Effect of Self-efficacy and Depression on Quality of Life in
Outpatients with CHF
Heart disease is one of the leading causes of death among
people with different racial and ethnic groups all over the
world. Heart failure occurs when the heart cannot pump enough
blood and oxygen to support other organs in our body. Although
it is a very serious condition, it doesn’t mean that the heart has
stopped beating but it causes people to have difficult time
performing their daily activities. About 6.2 million adults in
United States have heart failure and 659,000 people die from
the heart disease each year which is 1 in every 4 deaths (CDC,
3. 2020). According to CDC guidelines, the total cost of health
disease was estimated $363 billion from 2016 to 2017 which
includes the cost of health care services, medication and missed
days of work from an individual. Likewise, heart failure was
mentioned on 379,800 death certificates in 2018 (CDC, 2020).
Living with Chronic Heart Failure can be very challenging as
many of them report poor quality of life and emotional distres s.
The PICO question based on the topic of heart failure is, in
outpatient (25-50 years old) with chronic heart failure (P), how
does self-efficacy and depression (I) influence quality of life
(O) compared to having family support (C) over one year(T)?
In research study, participants were recruited through outpatient
cardiology clinics at a tertiary hospital in Singapore. Based on
the literature review, the study selected six factors (physical
and emotional dimensions, depression, self-efficacy, social
demographics, length of diagnosis and social support) to
identify the predictive factors of health-related quality of life of
outpatient with CHF by using multiple linear regression
analysis. Among these factors, only depression measured by SF-
CDS (ß= 0.637, p<0.001, 95%CI: 2.04-3.01) and self-efficacy
assessed by CSS (ß=-0.220, p<0.001,95%CI: -10.70 to -3.23)
were significant predictive factors of health-related quality of
life for outpatients with CHF accounting for nearly 70% of the
variance (Loo et al., 2016). Being able to perform daily living
activities increases the sense of living with the illness in the
patient. Higher level of self-efficacy like confidence in
managing the symptoms and self-care among the participants
have reported improved quality of life. Similarly, the patients
who don’t have adequate resources to deal with the challenges
associated with CHF should also be considered. CHF result in
limiting mental health along with the physical symptoms
leaving the individual with the feeling of helplessness.
Depression and anxiety level were found to negatively influence
individual psychosocial wellbeing since CHF patients must bear
a burden of having a disease. In this current study, depression
was identified as negative predictor of quality of life which is
4. consistent with previous research article. Based on these
finding, it is interference that lower self-efficacy and
depression predicted poor health related quality of life in
outpatients with CHF. This directly correlates the PICO
question as low self-efficacy and depression lowers the quality
of life compared to having a family support. Such predictor can
serve as an indicator for healthcare professionals to provide
interventions for potential psychosocial risk of depression
during the outpatient visit.
Reliability is mainly about the consistency in measurement
within the studies (Grove et al., 2015). In critiquing the
reliability of the Loo et al. (2016) article, the author used
questionnaires and scale that focuses on the physical and
emotional dimension, measures depression, assess patient’s
self-confidence and measure positive social support. Firstly, the
study uses The Minnesota Living with Heart Failure
Questionnaire (MLWHFQ) to measure how CHF has impacted
the quality of life grouped into physical and emotional
dimension with score ranging from 0 to 105 (Loo et al., 2016).
MLWHFQ has very high reliability with a Cronbach’s alpha of
0.95 for the overall scale and 0.94 to 0.95 for the subscales
(Loo et al., 2016). Additionally, the study also used short form-
cardiac depression scale (SF-CDS) that measures the depressed
mood in cardiac patients through 5-item self-rating scale.
Lastly, 16-item questionnaire Cardiac Self-Efficacy Scale (CSS)
assess the patient’s confidence with controlling sympto ms and
maintain functions (Loo et al., 2016). The internal consistency
of CSS from this study has acceptable Cronbach’s alpha of 0.86
(Loo et al., 2016). The questionnaire was provided to the
participants who met the criteria while they waited at the
cardiac clinic taking an average time of 20-30 minutes to
complete the questionnaires. So, Loo et al. (2016) article was
reliable in both its data collection and measurement methods.
Validity is defined with determining “how well the instrument
reflects the abstract concept being examined” (Grove et al.,
2015). In critiquing the validity of the Loo et al. (2016) article,
5. a cross-sectional, descriptive correlational study design was
used to conduct their study. The study looked at how self-
efficacy and depression impacts the quality of life of an
outpatient with CHF. The scale of depression and self-efficacy
was assessed based on SF-CDC and CDD respectively. Higher
score in SF-CDC indicates higher levels of depression
symptoms whereas higher CDD level indicates better ability to
cope with the demanding situation with high confidence (Loo et
al., 2016). Hence, Loo et al. (2016) showed validity in its
research design and measurement methods.
The research study conducted by Loo et al. (2016) had both
weakness and strength that stood out in the studies. A weakness
within the study was using a convenience sample of only
outpatient with a clinical diagnosis of CHF resulting a very
small sample size of 97 participants (Loo et al., 2016).
Although the self-reported questionnaires were advantageous in
gathering prospective data, response set bias would have
maximize the author’s ability to control the biases while
administering the forms (Loo et al., 2016). A strength within the
study was the use of 6-point Likert scale from 0(no impact) to
5(high impact) to score physical and emotional dimension rather
than having to answer the questions on their own (Loo et al.,
2016). Likewise, the author was able to create Chinese version
of MLWHFQ survey with a Cronbach’s alpha of 0.95 (Loo et
al., 2016). Having Cronbach’s alpha close to 1.0 gives the
strong consistency and less random error in the survey resulting
a strong reliability (Grove et al.,2015).
In the Guidelines for the Prevention, Detection, Evaluation and
Management of High Blood Pressure in Adult from American
Heart Association website, ACC and AHA collaborated with
NHLBI and other professional organizations to publish 4
guidelines based on assessment of CV risk, lifestyle
modification, management of obesity in the adults and
management of blood cholesterol in the adults (American Heart
Association, 2018). These guidelines evaluate and classify the
evidence to provide a quality of life by addressing the behavior
6. of self-management of blood pressure in addition to medication
adherence. The guidelines also address how certain
comorbidities such as CKD, ischemic heart disease, PAD, DM
affect the clinical decision-making in hypertension. The risk
factors of such comorbidities are common among adults with
hypertension and 71% of adults in United States diagnosed with
DM have hypertension (American Heart Association, 2018).
Correcting the dietary intake, excessive consumption of alcohol,
smoking, low fitness level and lifestyle changes with or without
pharmacological intervention is an important approach towards
managing and preventing hypertension. The second fact is
although the writing committee was able to correlate a vast
topic on the hypertension to make strong recommendation
across broad field of medical condition, significant gap in the
knowledge exist (American Heart Association, 2018). Further
research in decision-making with patient and their family is
needed where evidence doesn’t clearly identify if one treatment
is better than another. Lastly, the third fact is although these
clinical guidelines manage a large amount of accumulated
knowledge related to diagnosis of hypertension, it often causes
controversy when comparing recommendation made by different
expert (American Heart Association, 2018). The guidelines
emphasize how collaborating with patient increases provider’s
knowledge on the health outcome and quality of life to improve
the achievement of competing health concerns. All these
findings are relevant to PICO question and nursing practice
because they establish the need for non-pharmacological
interventions and lifestyle changes that can help patients
improve quality of life.
The systematic review article by Hodson et al. (2019) gives
further information on how family caregiver plays a vital role
taking care of the patient with Heart Failure and they should be
seen one of the important members of the health care team as
well. Although it takes time to develop strong base for
healthcare professional to work in direct contact with the
patient with advance heart failure, the experience of the
7. caregiver can be significantly improved by implementing some
minor changes in the clinical practice (Hodson et al., 2019).
Studies have shown those who lack the family caregiving
support feel overwhelmed by loneliness and lose hope for the
future easily demotivating them to perform self-care activities
and may cause depression. Additionally, the research has
demonstrated caregiver of spouse with unique caregiving
experiences compared to children, siblings and parents
reporting a lower quality of life, financial burden, and increase
risk of depression (Hodson et al., 2019). Caregivers make
various sacrifices like spend large amount of time at the home
setting which creates a sense of isolation from their surrounding
community. Although the caregiver experiences a higher degree
of burden while caring for advance heart failure patient, higher
self-efficacy indicates improved quality of life in the patient
with CHF in the presence of their family caregiver. The article
also mentioned that the unique needs of caregivers of those with
advance heart failure are not being met and aims to further
ascertain the gaps that require further exploration (Hodson et
al., 2019). These facts derived from the article is relevant to
PICO question and nursing practice because they contribute to
improve the current practice working with the caregiver of
person with HF.
To summarize, in outpatient (25-50 years old) with chronic
heart failure (P), how does self-efficacy and depression (I)
influence quality of life (O) compared to having family support
(C) over one year(T)? The lower self-efficacy and depression
predicted lower quality of life which served as indicator for
healthcare professionals to provide tailored interventions (Loo
et al., 2016). Many heart failure patients had trouble in self-care
and often needed the social support from their family that
reports improved quality of life. These results suggest that
increasement in self-efficacy have positive effect on the quality
of life in people who have CHF by reducing the potential
psychosocial risk of depression during the outpatient visit. The
findings from this study offered recommendations to future
8. studies for tailoring therapeutic interventions to improve health
related quality of life among CHF outpatients (Loo et al., 2016).
References
Centers for Disease Control and Prevention. (2020, September
8). Heart failure. Centers for Disease Control and Prevention.
Retrieved October 3, 2021, from
https://www.cdc.gov/heartdisease/heart_failure. htm.
Loo, D. W., Jiang, Y., Koh, K. W., Lim, F. P., & Wang, W.
(2016). Self-efficacy and depression predicting the health-
related quality of life of outpatients with chronic heart failure in
Singapore. Applied Nursing Research, 32, 148–155.
https://doi.org/10.1016/j.apnr.2016.07.007
Hodson, A. R., Peacock, S., & Holtslander, L. (2019). Family
caregiving for persons with Advanced Heart Failure: An
Integrative Review. Palliative and Supportive Care, 17(6), 720–
734. https://doi.org/10.1017/s1478951519000245
American Heart Association. 2017
ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/P
CNA Guideline for the Prevention, Detection, Evaluation, and
Management of High Blood Pressure in Adults: A Report of the
American College of Cardiology/American Heart Associati on
Task Force on Clinical Practice Guidelines. (2018).
Hypertension, 71(6).
9. https://doi.org/10.1161/hyp.0000000000000076
Grove, S.K., Gray, J.R., & Burns, N. (2015). Understanding
nursing research: Building an evidence-based practice (7th ed.).
St. Louis, MO: Elsevier Saunders.
EBP Project - Finding the Evidence
Assignment Instructions
In this assignment, students will be asked to create the initial
steps of an evidence based practice project using your topic and
the article you found in Finding a Quantitative Nursing
Research Article II (so long as it was approved). You will also
need your PICO(T) question that was approved in the Topic and
PICO(T) Question assignment. The student will locate several
additional resources to answer their PICO question, and write
this information into a paper using APA style. Please click on
the link below for more information, and watch your due dates
and times carefully. For additional help, use the Module 4
discussion board.
Finding the Evidence Paper Instructions-1.docx
Actions
Be very careful not to plagiarize in this assignment. Remember,
if you use a source and do not cite it, that is plagiarism. If you
have a direct quote from any source and it is not clearly
indicated as a quote in your paper, then even if you ci te it that
is plagiarism. IF SEVEN OR MORE WORDS ARE THE SAME
AS ANY SOURCE THAT IS A QUOTE AND MUST BE
MARKED AS SUCH. If you only change one or two words from
the source but keep the order of the ideas the same as in the
original, that is plagiarism. Go back to the plagiarism tutorial or
ask a librarian if you have any questions. Any instances of
plagiarism detected will result in your failing the course and
being referred to the Office of Community Standards.Submit
your EBP Project - Finding the Evidence assignment and your
10. nursing quantitative research article to the link above.
C L I N I C A L P R A C T I C E G U I D E L I N E
Treatment of Diabetes in Older Adults: An Endocrine
Society* Clinical Practice Guideline
Derek LeRoith,1 Geert Jan Biessels,2 Susan S. Braithwaite,3,4
Felipe F. Casanueva,5
Boris Draznin,6 Jeffrey B. Halter,7,8 Irl B. Hirsch,9 Marie E.
McDonnell,10
Mark E. Molitch,11 M. Hassan Murad,12 and Alan J. Sinclair13
1Icahn School of Medicine at Mount Sinai, New York, New
York 10029; 2University Medical Center Utrecht,
3584 CX Utrecht, Netherlands; 3Presence Saint Francis
Hospital, Evanston, Illinois 60202; 4Presence Saint
Joseph Hospital, Chicago, Illinois 60657; 5Complejo
Hospitalario Universitario de Santiago, CIBER de
Fisiopatologia Obesidad y Nutricion, Instituto Salud Carlos III,
15782 Santiago de Compostela, Spain;
6University of Colorado Denver Anschutz Medical Campus,
Aurora, Colorado 80045; 7University of
Michigan, Ann Arbor, Michigan 48109; 8National University of
Singapore, Singapore 119077, Singapore;
9University of Washington Medical Center–Roosevelt, Seattle,
Washington 98105; 10Brigham and Women’s
Hospital, Harvard Medical School, Boston, Massachusetts
02115; 11Northwestern University Feinberg
School of Medicine, Chicago, Illinois 60611; 12Division of
Preventive Medicine, Mayo Clinic, Rochester,
12. Abbreviations: ACE, angiotensin-converting enzyme; ACCORD,
Action to Control Car-
diovascular Risk in Diabetes; ADA, American Diabetes
Association; ADL, activity of daily
living; ARB, angiotensin receptor blocker; BP, blood pressure;
CGM, continuous glucose
monitoring; CHF, congestive heart failure; CKD, chronic kidney
disease; CVD, cardio-
vascular disease; DPP-4, dipeptidyl peptidase-4; eGFR,
estimated glomerular filtration
rate; FDA, Food and Drug Administration; GLP-1, glucagon-
like-peptide 1; GFR, glo-
merular filtration rate; HR, hazard ratio; IADL, instrume ntal
ADL; LDL-C, low-density li-
poprotein cholesterol; LTCF, long-term care facility; MACE,
major adverse cardiovascular
event; MCI, mild cognitive impairment; PCSK9, proprotein
convertase subtilisin/kexin type
9; RCT, randomized control trial; RR, relative risk; SGLT2,
sodium-glucose cotransporter 2;
SBP, systolic blood pressure; SDM, shared decision-making;
SPRINT, Systolic Blood
Pressure Intervention Trial; SU, sulfonylurea; T1D, type 1
diabetes; T2D, type 2 diabetes;
UKPDS, UK Prospective Diabetes Study; VEGF, vascular
endothelial growth factor.
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List of Recommendations
Role of the endocrinologist and diabetes
care specialist
1.1 In patients aged 65 years and older with newly
diagnosed diabetes, we advise that an endocri-
nologist or diabetes care specialist should work
with the primary care provider, a multidisciplinary
team, and the patient in the development of in-
dividualized diabetes treatment goals. (Ungraded
Good Practice Statement)
1.2 In patients aged 65 years and older with diabetes,
an endocrinologist or diabetes care specialist
should be primarily responsible for diabetes care
if the patient has type 1 diabetes, or requires complex
hyperglycemia treatment to achieve treatment goals,
or has recurrent severe hypoglycemia, or has multiple
diabetes complications. (Ungraded Good Practice
Statement)
14. Screening for diabetes and prediabetes, and
diabetes prevention
2.1 In patients aged 65 years and older without known
diabetes, we recommend fasting plasma glucose
and/or HbA1c screening to diagnose diabetes or
prediabetes. (1|����)
Technical remark: The measurement of HbA1c
may be inaccurate in some people in this age
group because of comorbidities that can affect the
lifespan of red blood cells in the circulation. Al -
though the optimal screening frequency for pa-
tients whose initial screening test is normal
remains unclear, the writing committee advocates
repeat screening every 2 years thereafter. As with
any health screening, the decision about diabetes
and prediabetes screening for an individual patient
depends on whether some action will be taken as a
result and the likelihood of benefit. For example,
such screening may not be appropriate for an older
patient with end-stage cancer or organ system
failure. In these situations, shared decision-making
with the patient is recommended.
2.2 In patients aged 65 years and older without
known diabetes who meet the criteria for pre-
diabetes by fasting plasma glucose or HbA1c, we
suggest obtaining a 2-hour glucose post–oral
glucose tolerance test measurement. (2|���O)
Technical remark: This recommendation is most
applicable to high-risk patients with any of the
following characteristics: overweight or obese,
first-degree relative with diabetes, high-risk race/
ethnicity (e.g., African American, Latino, Native
15. American, Asian American, Pacific Islander),
history of cardiovascular disease, hypertension
($140/90 mm Hg or on therapy for hypertension),
high-density lipoprotein cholesterol level ,35 mg/dL
(0.90 mmol/L) and/or a triglyceride level .250
mg/dL (2.82 mmol/L), sleep apnea, or physical
inactivity. Shared decision-making is advised for
performing this procedure in frail older people or
in those for whom it may be overly burdensome.
Standard dietary preparation for an oral glucose
tolerance test is advised.
2.3 In patients aged 65 years and older who have
prediabetes, we recommend a lifestyle program
similar to the Diabetes Prevention Program to
delay progression to diabetes. (1|����)
Technical remark: Metformin is not recommended
for diabetes prevention at this time, as it is not
approved by the Food and Drug Administration for
this indication. As of 2018, a Diabetes Prevention
Program–like lifestyle intervention is a covered
benefit for Medicare beneficiaries in the United
States who meet the criteria for prediabetes.
Assessment of older patients with diabetes
3.1 In patients aged 65 years and older with diabetes,
we advise assessing the patient’s overall health
(see Table 2) and personal values prior to the
determination of treatment goals and strategies (see
Table 3). (Ungraded Good Practice Statement)
3.2 In patients aged 65 years and older with diabetes,
we suggest that periodic cognitive screening
should be performed to identify undiagnosed
cognitive impairment. (2|��OO)
16. Technical remark: Use of validated self-administered
tests is an efficient and cost-effective way to imple-
ment screening (see text). Alternative screening test
options, such as the Mini-Mental State Examination
or Montreal Cognitive Assessment, are widely used.
An initial screening should be performed at the time
of diagnosis or when a patient enters a care program.
Screening should be repeated every 2 to 3 years
after a normal screening test result for patients
without cognitive complaints or repeated 1 year
after a borderline normal test result. Always evaluate
cognitive complaints and assess cognition in patients
with complaints.
3.3 In patients aged 65 years and older with diabetes
and a diagnosis of cognitive impairment (i.e., mild
cognitive impairment or dementia), we suggest
that medication regimens should be simplified (see
recommendation 3.1) and glycemic targets tailored
(i.e., be more lenient; see recommendation 4.1) to
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improve compliance and prevent treatment-related
complications. (2|��OO)
Technical remark: Medical and nonmedical
treatment and care for cognitive symptoms in
people with diabetes and cognitive impairment
are no different from those in people without
diabetes and cognitive impairment. Depending on
the situation and preferences of the patient,
a primary caregiver can be involved in decision-
making and management of medication.
Treatment of hyperglycemia
Setting glycemic targets and goals
4.1 In patients aged 65 years and older with diabetes,
we recommend that outpatient diabetes regimens
be designed specifically to minimize hypoglyce-
mia. (1|���O)
Technical remark: Although evidence for specific
targets is lacking, glycemic targets should be
tailored to overall health and management
strategies (e.g., whether a medication that can
cause hypoglycemia is used) (see Table 3).
Assessing glycemia in older adults with diabetes
4.2 In patients aged 65 years and older with diabetes
who are treated with insulin, we recommend
frequent fingerstick glucose monitoring and/or
18. continuous glucose monitoring (to assess glyce-
mia) in addition to HbA1c. (1|��OO)
Lifestyle interventions for older adults
with diabetes
Lifestyle modifications
4.3 In patients aged 65 years and older with diabetes
who are ambulatory, we recommend lifestyle
modification as the first-line treatment of hy-
perglycemia. (1|����)
Nutrition
4.4 In patients aged 65 years and older with diabetes,
we recommend assessing nutritional status to
detect and manage malnutrition. (1|����)
Technical remark: Nutritional status can be
assessed using validated tools such as the Mini
Nutritional Assessment and Short Nutritional
Assessment Questionnaire.
4.5 In patients aged 65 years and older with diabetes
and frailty, we suggest the use of diets rich in
protein and energy to prevent malnutrition and
weight loss. (2|��OO)
4.6 In patients aged 65 years and older with diabetes
who cannot achieve glycemic targets with lifestyle
modification, we suggest avoiding the use of re-
strictive diets and instead limiting consumption of
simple sugars if patients are at risk for malnu-
trition. (2|�OOO)
Technical remark: Patients’ glycemic responses to
19. changes in diet should be monitored closely. This
recommendation applies to both older adults living
in the community and those in nursing homes.
Drug therapy for hyperglycemia
Glycemic management of diabetes in older adults
with diabetes
4.7 In patients aged 65 years and older with diabetes,
we recommend metformin as the initial oral
medication chosen for glycemic management in
addition to lifestyle management. (1|���O)
Technical remark: This recommendation should
not be implemented in patients who have signif-
icantly impaired kidney function (estimated glo-
merular filtration rate ,30 mL/min/1.73 m2) or
have a gastrointestinal intolerance.
4.8 In patients aged 65 years and older with diabetes
who have not achieved glycemic targets with
metformin and lifestyle, we recommend that other
oral or injectable agents and/or insulin should be
added to metformin. (1|����)
Technical remark: To reduce the risk of hypo-
glycemia, avoid using sulfonylureas and glinides,
and use insulin sparingly. Glycemic treatment
regimens should be kept as simple as possible.
Treating complications of diabetes
Management of hypertension in older adults
with diabetes
5.1 In patients aged 65 to 85 years with diabetes, we
recommend a target blood pressure of 140/90 mm
20. Hg to decrease the risk of cardiovascular disease
outcomes, stroke, and progressive chronic kidney
disease. (1|���O)
Technical remark: Patients in certain high-risk
groups could be considered for lower blood
pressure targets (130/80 mm Hg), such as those
with previous stroke or progressing chronic kid-
ney disease (estimated glomerular filtration
rate ,60 mL/min/1.73 m2 and/or albuminuria). If
lower blood pressure targets are selected, careful
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monitoring of such patients is needed to avoid
orthostatic hypotension. Patients with high dis-
ease complexity (group 3, poor health, Table 3)
could be considered for higher blood pressure
targets (145 to 160/90 mm Hg). Choosing a blood
pressure target involves shared decision-making
21. between the clinician and patient, with full dis-
cussion of the benefits and risks of each target.
5.2 In patients aged 65 years and older with diabetes
and hypertension, we recommend that an angiotensin-
convertingenzymeinhibitororanangiotensinreceptor
blocker should be the first-line therapy. (1|���O)
Technical remark: If one class is not tolerated, the
other should be substituted.
Management of hyperlipidemia in older adults
with diabetes
5.3 In patients aged 65 years and older with diabetes,
we recommend an annual lipid profile. (1|��OO)
5.4 In patients aged 65 years and older with diabetes,
we recommend statin therapy and the use of an
annual lipid profile to achieve the recommended
levels for reducing absolute cardiovascular dis-
ease events and all-cause mortality. (1|����)
Technical remark: The Writing Committee did
not rigorously evaluate the evidence for specific
low-density lipoprotein cholesterol targets in this
population, so we refrained from endorsing spe-
cific low-density lipoprotein cholesterol targets in
this guideline. For patients aged 80 years old and
older or with short life expectancy, we advocate
that low-density lipoprotein cholesterol goal levels
should not be so strict.
5.5 In patients aged 65 years and older with diabetes,
we suggest that if statin therapy is inadequate for
reaching the low-density lipoprotein cholesterol
reduction goal, either because of side effects or
because the low-density lipoprotein cholesterol
22. target is elusive, then alternative or additional
approaches (such as including ezetimibe or pro-
protein convertase subtilisin/kexin type 9 in-
hibitors) should be initiated. (2|�OOO)
5.6 In patients aged 65 years and older with diabetes
and fasting triglycerides .500 mg/dL, we rec-
ommend the use of fish oil and/or fenofibrate to
reduce the risk of pancreatitis. (1|��OO)
Management of congestive heart failure in older
adults with diabetes
5.7 In patients aged 65 years and older who have
diabetes and congestive heart failure, we advise
treatment in accordance with published clinical
practice guidelines on congestive heart failure.
(Ungraded Good Practice Statement)
5.8 In patients aged 65 years and older who have
diabetes and congestive heart failure, the fol-
lowing oral hypoglycemic agents should be pre-
scribed with caution to prevent worsening of
heart failure: glinides, rosiglitazone, pioglitazone,
and dipeptidyl peptidase-4 inhibitors. (Ungraded
Good Practice Statement)
Management of atherosclerosis in older adults
with diabetes
5.9 In patients aged 65 years and older with diabetes
and a history of atherosclerotic cardiovascular
disease, we recommend low-dosage aspirin (75 to
162 mg/d) for secondary prevention of cardio-
vascular disease after careful assessment of
23. bleeding risk and collaborative decision-making
with the patient, family, and other caregivers.
(1|��OO)
Eye complications in older adults with diabetes
5.10 In patients aged 65 years and older with diabetes,
we recommend annual comprehensive eye ex-
aminations to detect retinal disease (1|����).
Technical remark: Screening and treatment
should be conducted by an ophthalmologist or
optometrist in line with present-day standards.
Neuropathy, falls, and lower extremity problems in
older adults with diabetes
5.11 In patients aged 65 years and older with di-
abetes and advanced chronic sensorimotor
distal polyneuropathy, we suggest treatment
regimens that minimize fall risk, such as the
minimized use of sedative drugs or drugs that
promote orthostatic hypotension and/or hy-
poglycemia. (2|�OOO)
5.12 In patients aged 65 years and older with diabetes
and peripheral neuropathy with balance and gait
problems, we suggest referral to physical ther-
apy or a fall management program to reduce the
risk of fractures and fracture-related complications.
(2|�OOO)
5.13 In patients aged 65 years and older with diabetes
and peripheral neuropathy and/or peripheral
vascular disease, we suggest referral to a podi-
atrist, orthopedist, or vascular specialist for
preventive care to reduce the risk of foot ul-
24. ceration and/or lower extremity amputation.
(2|��OO)
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Chronic kidney disease in older adults with diabetes
5.14 In patients aged 65 years and older with diabetes
who are not on dialysis, we recommend annual
screening for chronic kidney disease with an
estimated glomerular filtration rate and urine
albumin-to-creatinine ratio. (1|����)
5.15 In patients aged 65 years and older with diabetes
who are in group 3 (poor health, see Table 3) of
the framework and have a previous albumin-to-
creatinine ratio of ,30 mg/g, we suggest against
25. additional annual albumin-to-creatinine ratio
measurements. (2|��OO)
5.16 In patients aged 65 years and older with diabetes
and decreased estimated glomerular filtration
rate, we recommend limiting the use or dosage of
many classes of diabetes medications to mini-
mize the side effects and complications associ-
ated with chronic kidney disease. (1|��OO)
Technical remark: Specific use/dosing guidance
on each class of diabetes medication is provided
in Table 7.
Special settings and populations
Management of diabetes away from home—in
hospitals and long-term care facilities—and
transitions of care
6.1 In patients aged 65 years and over with diabetes
in hospitals or nursing homes, we recommend
establishing clear targets for glycemia at 100 to
140 mg/dL (5.55 to 7.77 mmol/L) fasting and 140
to 180 mg/dL (7.77 to 10 mmol/L) postprandial
while avoiding hypoglycemia. (1|��OO)
Technical remark: An explicit discharge plan
should be developed to reestablish long-term glyce-
mic treatment targets and glucose-lowering medica-
tions as the patient transitions to posthospital care.
6.2 In patients aged 65 years and older with diabetes
and a terminal illness or severe comorbidities, we
recommend simplifying diabetes management
strategies. (1|�OOO)
6.3 In patients aged 65 years and older without diagnosed
26. diabetes, we suggest routine screening for HbA1c
during admission to the hospital to ensure detection
and treatment where needed (see the technical remark
in recommendation 2.1). (2|��OO)
Introduction
Scope of guideline
In recognition of the broad nature of the topic, the
Writing Committee has identified topics deemed to have
the greatest impact on the overall health and quality of
life of older individuals (defined here as age 65 years or
older) with diabetes. The Writing Committee has chosen
to use the American Diabetes Association (ADA) defi-
nitions for diabetes and prediabetes (see section 2 on
“Screening for Diabetes and Prediabetes, and Diabetes
Prevention”). We discuss pathophysiology and epide-
miology unique to older adults, evidenced-based treat-
ment strategies, such as lifestyle management and drug
therapy, and the identification and management of
common comorbidities and diabetes-related complica-
tions, such as hypertension, hyperlipidemia, congestive
heart failure (CHF), retinopathy, neuropathy, and
chronic kidney disease (CKD). We also discuss special
settings and type 1 diabetes (T1D). Some topics, such as a
detailed discussion on the use of devices and technology,
are identified as being important for the care of pa-
tients with diabetes but are beyond the scope of the
guideline. Furthermore, we emphasize the heterogeneity
of the older adult population with diabetes and provide
guidance for individualization of treatment plans by
creating a conceptual framework that suggests three
categories of overall health (see “Assessment of Older
Patients With Diabetes”). This framework is discussed in
27. detail in section 3 and referenced in specific recom-
mendations wherever relevant. Lastly, members of the
Writing Committee sought to incorporate the patient’s
voice into this guideline by developing and administering
a brief survey in collaboration with patient advocacy
organizations/community organizers who helped us
identify individuals with diabetes for participation. The
results of this survey are reported in a designated section
in Appendix B.
Epidemiology
Among older adults with diabetes, .90% have type 2
diabetes (T2D), and in one study, this value was 96% (1).
T2D is an age-related disease with a prevalence of 33% in
the US population aged 65 years or older, and nearly
50% of older people meet the criteria for prediabetes (2).
The incidence of newly diagnosed diabetes is highest
among those aged 65 to 79 years. The reported duration
of T2D among older people is illustrated in Fig. 1 (3).
Although nearly half of those with diabetes aged 60 to 69
years report having had the disease for .10 years, ;20%
of individuals over the age 80 years report a duration
of ,5 years. However, the duration of T2D may be
underestimated unless individuals are screened regularly.
The prevalence of diabetes in the United States is pro-
jected to increase dramatically during the next 3 decades;
as the population ages, the numbers of higher-risk mi-
nority groups increase, and people with diabetes live
longer because of decreasing rates of cardiovascular
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deaths (4). Moreover, older adults are susceptible to all of
the usual complications of diabetes [reviewed in Refs. (3)
and (5)]. The prevalence rates of end-stage renal disease,
loss of vision, myocardial infarction, stroke, peripheral
vascular disease, and peripheral neuropathy are in-
creased by the presence of diabetes, as illustrated in Fig. 2
for cardiovascular diseases (CVDs) and in Fig. 3 for
microvascular complications (3).
The dramatic effect of age on the incidence of major
diabetes complications is illustrated in Fig. 4 (6). As
summarized in Halter et al. (7), ;50% of individuals
over age 65 years with diabetes have diabetic nephrop-
athy, which manifests as albuminuria, impaired glomerular
filtration rate (GFR), or both. Diabetic kidney disease ac-
counts for nearly half of all cases of end-stage renal disease
in the United States, and the rate is highest among those
aged $75 years. The risk for lower extremity amputation is
10-fold greater in older people with diabetes than in those
without diabetes.
29. Pathophysiology of hyperglycemia
A detailed discussion of the pathophysiol ogy of T2D
and its relationship to aging is beyond the scope of this
report. As summarized recently (8), T2D occurs in the
Figure 2. Cardiovascular complications among adults age $65 y,
by diabetes status, United States, 2007–2010. Data are self-
reported. Error bards represent 95% CIs. [Reproduced from
Laiteerapong N, Huang ES. Chapter 16: Diabetes in older
adults. In
Cowie CC, Casagrande SS, Menke A, et al., eds. Diabetes in
America, 3rd ed. Bethesda, MD: National Institutes of Health,
NIH
Pub No. 17-1468, 2017; pp 16-1 to 16-26.]
Figure 3. Microvascular complications among adults age $65 y,
by
diabetes status, United States, 2005–2010. Diabetes status is
self-
reported. Error bars represent 95% CIs. *Retinopathy detected
by
nonmydriatic digital fundus photography. Based on 2005–2008
data. †Microalbuminuria defined as an albumin-to-creatinine
ratio
of 30 to 300 mg/g. Based on 2007–2010 data. ‡Decreased
kidney
function based on eGFR ,60 mL/min/1.73 m2 determined using
the
CKD-EPI equation and serum creatinine. 1Estimate is too
unreliable
to present; one case (or no cases) or relative SE .50%.
[Reproduced from Laiteerapong N, Huang ES. Chapter 16:
Diabetes
in older adults. In Cowie CC, Casagrande SS, Menke A, et al.,
eds.
30. Diabetes in America, 3rd ed. Bethesda, MD: National Institutes
of
Health, NIH Pub No. 17-1468, 2017; pp 16-1 to 16-26.]
Figure 4. Incidence (per 1000) of major diabetes complications
according to age among adults with diabetes, 2009 (6). ER,
emergency room; ESRD, end-stage renal disease; IHD, ischemic
heart disease. [Reproduced from the National Diabetes
Surveillance
System at http://www.cdc.gov/diabetes]
Figure 1. Duration of diabetes among adults aged $60 y, by age,
United States, 2009–2010 (3). [Reproduced from Laiteerapong
N,
Huang ES. Chapter 16: Diabetes in older adults. In Cowie CC,
Casagrande SS, Menke A, et al., eds. Diabetes in America, 3rd
ed.
Bethesda, MD: National Institutes of Health, NIH Pub No. 17-
1468,
2017; pp 16-1 to 16-26.]
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older population as a result of a complex interaction
among genetic, lifestyle, and aging influences [see Fig. 5
(9)]. This complexity means that there is substantial
heterogeneity in the pathophysiology, clinical features,
and rate of progression of the disease among older
people. A recent review summarizes the effects of aging
on glucose tolerance and insulin secretion (8). Notably,
consistent declines in b cell function and insulin secretion
are hallmarks of aging in rodents and humans (10–18).
These impairments limit the response to lifestyle-induced
insulin resistance, resulting in progression to prediabetes
and T2D. Glucose toxicity from chronic exposure to
hyperglycemia can worsen insulin resistance and further
impair pancreatic b cell function (19). Thus, hypergly-
cemia in diabetes may drive further worsening of age-
related impairments of both b cell function and
proliferation. Lipotoxicity from exposure to products of
fat cell lipolysis may also contribute to this vicious cycle
(20), as do visceral obesity and intramyocellular fat.
The heterogeneity of T2D likely reflects the varying
contributions of multiple factors to the development of
hyperglycemia in a given individual or family. Un-
derstanding these factors for an individual patient may
provide a basis for the selection of glucose-lowering
interventions (8).
Systematic Review and Meta-Analyses
The Writing Committee commissioned two systematic
32. reviews to support this guideline. Both reviews focused
on individuals aged 65 years and older. Although the
target population of this guideline is individuals with
diabetes, concerns about not identifying sufficient evi -
dence necessitated that the two systematic reviews
summarize evidence on individuals with and without
diabetes (presented separately).
The first review attempted to answer the follow-
ing question: In older individuals, does treatment with
antihypertensive pharmacologic therapy lead to im-
provement in patient-important outcomes? The review
identified 19 randomized trials. Antihypertensive therapy
was associated with a reduction in all-cause mortality,
cardiovascular mortality, myocardial infarction, heart
failure, stroke, and CKD. Older patients with diabetes
treated with antihypertensive therapy had lower risk of
CKD without a significant reduction in other outcomes;
however, there was no significant difference in estimates of
beneficial effects between those with and without diabetes.
The second review attempted to answer the following
question: In older individuals, does treatment with lipid-
lowering pharmacologic therapy lead to improvement in
patient-important outcomes? The review identified 23
randomized trials. For primary prevention, statins re-
duced the risk of coronary artery disease and myocardial
infarction, but not all-cause or cardiovascular mortality
or stroke. These effects were imprecise in patients with
diabetes, but there was no significant interaction between
diabetes status and the intervention effect. For secondary
prevention, statins reduced all-cause mortality, cardio-
vascular mortality, coronary artery disease, myocardial
infarction, and revascularization. Intensive (vs less in-
tensive) statin therapy reduced the risk of coronary artery
33. disease and heart failure.
In both of the systematic reviews, the quality of evi-
dence, or certainty in the estimates, was high for most
outcomes when evaluated in all older patients. When the
evaluation was restricted to those with diabetes, the es-
timates of beneficial effects were generally similar to
those observed in all older patients, but the CIs were
relatively wide, indicating imprecision. Accordingly, the
corresponding quality of evidence was considered to be
moderate for older patients with diabetes. There was also
no significant difference in estimates (interaction) be-
tween those with and without diabetes, suggesting that
extrapolation of data from the older population at large
to older individuals with diabetes is reasonable.
Figure 5. Model for age-related hyperglycemia (9). [Adapted
with permission from Chang AM, Halter JB. Aging and insulin
secretion. Am J
Physiol Endocrinol Metab 2003;284:E7–E12.]
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34. ber 2021
1. Role of the Endocrinologist and Diabetes
Care Specialist
1.1 In patients aged 65 years and older with newly
diagnosed diabetes, we advise that an endocri-
nologist or diabetes care specialist should work
with the primary care provider, a multidisci-
plinary team, and the patient in the development
of individualized diabetes treatment goals. (Un-
graded Good Practice Statement)
1.2 In patients aged 65 years and older with diabetes,
an endocrinologist or diabetes care specialist
should be primarily responsible for diabetes care
if the patient has T1D, or requires complex hy-
perglycemia treatment to achieve treatment goals,
or has recurrent severe hypoglycemia, or has
multiple diabetes complications. (Ungraded Good
Practice Statement)
Evidence
Given the heterogeneity of the population of older
adults with diabetes, the role of the endocrinologist or the
diabetes care specialist in the care of an individual patient
may vary considerably during the course of the disease.
Decision-making about this role requires active partici-
pation and good lines of communication among the
endocrinologist or diabetes care specialist, the primary
care physician, and the patient. Because of the high
burden of diabetes and its complications on overall
health status (21, 22), many older patients benefit from
35. care by an interdisciplinary team. The endocrinologist or
diabetes care specialist functions as the leader of the
diabetes care team, which includes a nurse educator,
dietician, and others (e.g., pharmacist, psychologist,
social worker). The endocrinologist or diabetes care
specialist may also serve the medical community by
providing up-to-date training in the care of older patients
with diabetes. Possible roles of the endocrinologist or
diabetes care specialist include the following.
No role. Diabetes care is provided by the patient’s pri -
mary care team, which has received up-to-date training in
the care of older patients with diabetes. An endocrinol -
ogist or diabetes care specialist may not be needed for
patients whose hyperglycemia and CVD prevention
treatment goals are easily achieved with lifestyle alone or
with simple oral agent therapy (one or two medications).
Application of the Chronic Disease Model can facilitate
diabetes quality care in the primary care setting (23).
Consultant-only collaborative care. Overall diabetes
care is provided by the patient’s primary care team.
The endocrinologist or diabetes care specialist assists
in assessing the patient’s diabetes status and related
complications and setting treatment goals with recom-
mendations for specific interventions. Consultation may
occur at the time of original diabetes diagnosis or when
there is a change in the patient’s diabetes status (e.g.,
treatment goals no longer being achieved, recurrent
hypoglycemia, development of one or more diabetes
complications). Consultation may involve only a member
(not all) of the diabetes care team (e.g., nurse educator or
dietician). The endocrinologist or diabetes care specialist
may be asked to initiate insulin therapy for a patient and
then send the patient back to the primary care provider
36. once stable, or they may consult to assist with glycemic
management when a patient is hospitalized.
Overall diabetes management. For selected patients, the
endocrinologist or diabetes care specialist and the di -
abetes care team are primarily responsible for diabetes
care and collaborate with providers who manage the
patient’s other health problems and comorbidities. This
situation may occur by default if the patient has no
primary care provider or if the patient is already under
the care of the endocrinologist or diabetes care specialist
for long-standing T1D or other endocrine conditions.
Specific indications for the endocrinologist or diabetes care
specialist to assume control of overall diabetes manage-
ment for an older patient include complex hyperglycemia
treatment (use of three or more glucose-lowering agents;
the addition of insulin, especially multiple types or in-
jections), recurrent severe hypoglycemia, multiple diabetes
complications, and a long history of diabetes.
2. Screening for Diabetes and Prediabetes,
and Diabetes Prevention
2.1 In patients aged 65 years and older without
known diabetes, we recommend fasting plasma
glucose and/or HbA1c screening to diagnose di-
abetes or prediabetes. (1|����)
Technical remark: The measurement of HbA1c
may be inaccurate in some people in this age
group because of comorbidities that can affect
the lifespan of red blood cells in the circulation.
Although the optimal screening frequency for
patients whose initial screening test is normal
remains unclear, the writing committee advo-
cates repeat screening every 2 years thereafter. As
with any health screening, the decision about
37. diabetes and prediabetes screening for an indi-
vidual patient depends on whether some action
will be taken as a result and the likelihood of
benefit. For example, such screening may not
be appropriate for an older patient with end-
stage cancer or organ system failure. In these
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situations, shared decision-making with the pa-
tient is recommended.
2.2 In patients aged 65 years and older without
known diabetes who meet the criteria for pre-
diabetes by fasting plasma glucose or HbA1c, we
suggest obtaining a 2-hour glucose post–oral
glucose tolerance test measurement. (2|���O)
38. Technical remark: This recommendation is most
applicable to high-risk patients with any of the
following characteristics: overweight or obese,
first-degree relative with diabetes, high-risk race/
ethnicity (e.g., African American, Latino, Native
American, Asian American, Pacific Islander),
history of CVD, hypertension ($140/90 mm Hg
or on therapy for hypertension), high-density
lipoprotein cholesterol level ,35 mg/dL (0.90
mmol/L) and/or a triglyceride level .250 mg/dL
(2.82 mmol/L), sleep apnea, or physical inactivity.
Shared decision-making is advised for performing
this procedure in frail older people or in those for
whom it may be overly burdensome. Standard
dietary preparation for an oral glucose tolerance
test is advised.
2.3 In patients aged 65 years and older who have
prediabetes, we recommend a lifestyle program
similar to the Diabetes Prevention Program to
delay progression to diabetes. (1|����)
Technical remark: Metformin is not recommended
for diabetes prevention at this time, as it is not
approved by the Food and Drug Administration for
this indication. As of 2018, a Diabetes Prevention
Program–like lifestyle intervention is a covered
benefit for Medicare beneficiaries in the United
States who meet the criteria for prediabetes.
Evidence
The ADA defines diabetes and prediabetes based
on glucose measures (24). Importantly, individuals with
prediabetes are at increased risk for progression to di -
abetes and development of CVDs; Table 1 (24) lists the
39. ADA criteria for prediabetes and diabetes. The fasting
plasma glucose and HbA1c categories allow easy iden-
tification of both diabetes and prediabetes. However,
many people over the age of 60 years affected with
diabetes and prediabetes are not diagnosed unless
an oral glucose tolerance test is performed (2). Impor-
tantly, individuals with prediabetes are at increased
risk for progression to diabetes and development of
CVDs. Population screening demonstrates a high rate of
detection of newly diagnosed diabetes. Additionally,
modeling such studies suggests that early detection and
treatment of diabetes can reduce long-term complications
(25). Furthermore, diabetes and prediabetes criteria
predict risk for subsequent diabetes and CVD similarly in
both older and younger people. The prevalence of dis-
orders of sleep increases with age, and such disorders
have been associated with the development or exacer-
bation of diabetes and risks of cardiovascular events.
Therefore, assessment for sleep disorders and their
treatment should be considered in older patients at risk
for and with diabetes (26).
Progression from prediabetes to diabetes can be
slowed substantially (27–30). Evidence supporting this
observation includes recent meta-analyses involving
Table 1. ADA Criteria for Prediabetes and Diabetes
Prediabetesa Diabetesb
FPG 100 mg/dL (5.6 mmol/L) to 125 mg/dL (6.9 mmol/L) 5 IFG
FPG $126 mg/dL (7.0 mmol/L)
OR OR
2-h PG during 75-g OGTT 140 mg/dL (7.8 mmol/L) to 199
mg/dL
40. (11.0 mmol/L) 5 IGT
2-h PG $200 mg/dL (11.1 mmol/L)
during OGTTc
OR OR
A1C 5.7%–6.4% (39–47 mmol/mol)d A1C $6.5% (48
mmol/mol)d
OR
In a patient with classic symptoms of hyperglycemia
or hyperglycemic crisis, a random PG $200
mg/dL (11.1 mmol/L).
[Data from American Diabetes Association. 2. Classification
and diagnosis of diabetes: standards of medical care in diabetes -
2019. Diabetes Care. 2019;
42:S13–s28].
Abbreviations: FPG, fasting PG; IFG, impaired fasting glucose;
IGT, impaired glucose tolerance; OGTT, oral glucose tolerance
test; PG, plasma glucose.
aFor all three tests, risk is continuous, extending below the
lower limit of the range and becoming disproportionately
greater at the higher end of the
range.
bIn the absence of unequivocal hyperglycemia, diagnosis
requires two abnormal test results from the same sample or in
two separate test samples.
cThe test should be performed as described by the World Health
Organization, using a glucose load containing the equivalent of
75-g anhydrous glucose
dissolved in water.
dThe test should be performed in a laboratory using a method
that is National Glycohemoglobin Standardization Program
certified and standardized to
41. the Diabetes Control and Complications Trial assay.
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nearly 50,000 subjects (31, 32). In people over the age of
60 years in the Diabetes Prevention Program, lifestyle in-
terventiontoreducebodyweightandincreasephysical activity
reduced the rate of progression to diabetes by 71% during
4 years (estimated number needed to treat to prevent one
person progressing to diabetes, 5.6). The reduced rate of
progression to diabetes was maintained during 15 years of
follow-up, although the lifestyle intervention was much less
intenseduringthelast10years(28,29).Notably,theimpactof
this intervention is cost-effective (27). Additionally, metformin
was less effective in people over the age of 60 years (estimated
number needed to treat, 39.2) in the Diabetes Prevention
Program, and the meta-analyses suggest that drug treatment
tends to have transitory effects on diabetes prevention.
42. 3. Assessment of Older Patients
With Diabetes
Overall health framework
3.1 In patients aged 65 years and older with diabetes,
we advise assessing the patient’s overall health
(see Table 2) and personal values prior to the
determination of treatment goals and strategies
(see Table 3). (Ungraded Good Practice Statement)
Evidence
The treatment strategies and goals developed for older
adults depend on overall patient health, including medical
complexity and functional status. Table 2 (33, 34) provides a
guide for the comprehensive assessment of the older
adult, including the general medical assessment and
diabetes-focused evaluations. Functional status refers
to a person’s ability to perform normal daily activities
required to meet basic needs, fulfill usual roles, and
maintain health and well-being (35). Both aging
and diabetes are independent risk factors for impaired
functional status, and the interaction of these two
factors is highly complex and unique for each patient.
For this reason, recent diabetes guidelines have gener-
ally concluded that care of the aging patient with di-
abetes requires an individualized, rather than purely
algorithmic, approach (36–38). However, there is no
standard tool recommended for the assessment and
documentation of how effectively older adults function in
their lives. Functional status is most often documented
using subsets of specific activities that are necessary for
living independently. They include activities of daily living
(ADLs), that is, bathing, dressing, eating, toileting, and
43. transferring, as well as instrume ntal ADLs (IADLs), that is,
preparing meals, shopping, managing money, using the
telephone, and managing medications (Table 2) (34). In
patients with diabetes, deficits in IADLs identified during
routine evaluation should trigger a more in-depth evalu-
ation of the patient, including a detailed assessment of
hypoglycemia and hyperglycemia, microvascular and
macrovascular complications, and cognition, as discussed
in depth in this guideline.
Table 2. Clinical Care of Older People
General Health Assessmenta General Health Testsb Diabetes-
Specific Healthc
Functional status (ADLs/IADLsd) ECG Retinopathy
Depression Lipid panel Nephropathy
Cognition Bone mineral density Neuropathy
Fall risk AAA ultrasound Medical nutrition therapy
Weight (kg)/height (m)2 = BMI Diabetes screening (for
nondiabetic persons) Diabetes management
Blood pressure Diabetes self-management training
Tobacco use
Alcohol use
Medication review
Cancer screening
Hearing
Comorbid conditions
Visual acuity
Frailty/physical performance
Abbreviations: AAA, abdominal aortic aneurysm; ADL, activity
of daily living; BMI, body mass index; IADL, instrumental
activity of daily living.
aAll items are required services to qualify for Medicare
coverage of annual wellness examinations for people in the
44. United States .65 y of age, except for
frailty/physical performance (33). These are generally
conducted by primary care providers.
bAll items are services covered by Medicare for people in the
United State .65 y of age as part of annual wellness
examinations at intervals varying from
annually to once per lifetime (33).
cAll items are services covered by Medicare for people in the
United States .65 y of age as part of standard diabetes care (33).
These are covered annually
except for diabetes management visits, which are covered as
recommended by the diabetes care team.
dFunctional status is based on assessment of independence or
dependency (having difficulty and receiving assistance) of five
ADLs (bathing, dressing,
eating, toileting, and transferring) and five IADLs (preparing
meals, shopping, managing money, using the telephone, and
managing medications) (34).
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Table 3. Conceptual Framework for Considering Overall Health
and Patient Values in Determining Clinical
Targets in Adults Aged 65 y and Older
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Overall health in older adults has been described in
terms of frameworks or categories that guide the clinician
to consider multiple factors when assessing the health of
an adult over the age of 65 years. One such framework
was developed by Blaum et al. (35) and was incorporated
into the 2012 ADA consensus report on the care of older
adults with diabetes. The Blaum framework suggests
considering chronic diseases (fewer than three vs three
or more), cognitive or visual impairment (none, mild,
46. moderate to severe), and IADL dependencies (none vs
two or more) to define functional status. This frame-
work was used to identify three classes of patients
corresponding to increasing levels of mortality risk and
was thus validated as a tool for determining the like-
lihood of benefit of a treatment strategy based on life
expectancy (39). Using this evidence, the Blaum cate-
gories and the 2012 ADA consensus report as guides, we
developed a conceptual framework for overall health
that categorizes patients into good health (group 1),
intermediate health (group 2), and poor health (group
3) groups [Table 3 (39, 40) and “Setting glycemic
targets and goals” under section 4 on “Treatment of
Hyperglycemia”].
Frailty
Frailty can be defined as a state of increased vul -
nerability to physical or psychological stressors
because of decreased physiological reserves in mul-
tiple organ systems that cause a limited capacity
to maintain homeostasis. Moreover, it represents a
predisability condition that can be responsive to in-
tervention (41).
Screening for geriatric syndromes, including frailty,
should be part of a stepped-care approach in older people
with diabetes, particularly in primary and community
care settings. Where there is evidence of moderate to
severe physical or cognitive impairment or functional
loss, referral to geriatricians or other skilled clinicians
for a comprehensive assessment is needed. The impor-
tance of detecting frailty lies in the opportunity to con-
sider targeted interventions that reduce functional decline
and risk of disability.
47. Any report of a change in mobility, presence of falls,
noticeable decrease in IADLs after recent discharge
from a hospital, or presence of continuing fatigue should
prompt the clinician to screen for functional loss and/or
frailty [Table 4 (42–45)]. An initial screen for physical
impairment can be obtained by using the following
commonly employed measures in geriatric practice (46)
[Table 5 (47–51)].
Screening for sarcopenia
Sarcopenia is an age-related loss of muscle mass that
has now been linked to progressive loss of muscle
strength and reduced physical performance (52). Sar-
copenia is accelerated in the presence of diabetes. Cli -
nicians can refer patients with possible sarcopenia for a
dual-energy X-ray absorptiometry scan, but this pro-
cedure is expensive and may not be convenient. Bio-
electrical impedance analysis is an alternative method for
the assessment of lean muscle mass and may be con-
sidered in place of dual-energy X-ray absorptiometry
scanning. Alternatively, a rapid screening test for sar-
copenia in a clinical setting can be obtained using a
simple five-question instrument called the Sarc-F, which
looks at fall history, ability to lift objects, and difficulties
with mobility. This scale has been validated extensively
and has been shown to be highly predictive of future
disability and hospitalization (53).
Table 4. Tools to Detect Frailty
Assessment Tool Comments
Fried score Well-established physical frailty tool based on data
from the
48. Cardiovascular Health Study; often seen as a reference frame
for studies of frailty in community-dwelling older adults;
requires two procedures/measures (gait speed and grip
strength) and answers to three questions (relating to weight
loss, level of exhaustion, and amount of physical activity); can
identify “prefrail” individuals (42).
Clinical Frailty Scale (Note: A larger 70-item assessment
tool called the Frailty Index is also available.)
Based on data from the Canadian Study of Health and Aging;
seven-point scale; predictive of future events including
mortality; easy to employ in routine clinical practice (43).
FRAIL score Well-validated in multiple population groups;
sensitivity and
specificity similar to that of the Fried scale. Comprises only
five
questions (no procedures) covering fatigue, climbing stairs,
walking, number of illnesses, and weight loss (44).
[Reproduced with permission from Sinclair AJ, Abdelhafiz A,
Dunning T, Izquierdo M, Rodriguez Manas L, Bourdel-
Marchasson I, Morley JE, Munshi M,
Woo J, Vellas B. An international position statement on the
management of frailty in diabetes mellitus: summary of
recommendations 2017. J Frailty
Aging 2018;7:10–20.] (45)
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Cognitive impairment in older adults with diabetes
In the general population, the prevalence of dementia
increases from 1% to 2% at ages 60 to 64 years to 6% to
9% at ages 75 to 79 years to well above 35% in those
who are 90 years and older (54). The population burden
of cognitive impairment in older individuals is even larger
if predementia stages of cognitive dysfunction, such as
mild cognitive impairment (MCI), are also considered.
Epidemiological studies have found clear associations
between diabetes and dementia risk (55). A meta-analysis
including over 1 million individuals presented a pooled
overall relative risk (RR) for dementia in people with
diabetes of 1.73 (95% CI, 1.65 to 1.82) compared to
people without diabetes (56). This increased risk was
present in both Alzheimer’s disease (RR, 1.56; 95% CI,
1.41 to 1.73) and vascular dementia (RR, 2.27; 95% CI,
1.94 to 2.66) (56); notably, however, Alzheimer’s disease
generally was not diagnosed with biomarker support in
these epidemiological studies. Neuropathological studies
indicate that diabetes is primarily associated with an
50. increase in the burden of vascular pathologies rather than
plaques and tangles, the neuropathological hallmarks of
Alzheimer’s disease (57). Moreover, diabetes is associ -
ated with an increased risk of MCI (RR, 1.21; 95% CI,
1.02 to 1.45) (58) and an increased rate of conversion
from MCI to dementia (OR, 1.65; 95% CI, 1.12 to 2.43)
(59). Of note, these numbers primarily apply to patients
with T2D because data on older individuals with T1D are
still scarce.
With the aging of the population and trends in di-
abetes prevalence, the combination of cognitive im-
pairment and diabetes is likely to become more common,
having implications for diabetes care. Clearly, cognitive
impairment in patients with diabetes is associated with
poorer diabetes self-management and glycemic control
(60, 61), an increased frequency of hospital admissions
and occurrence of severe hypoglycemic episodes (62, 63),
and an increased occurrence of major cardiovascular
events and death (64). Early identification of individuals
with cognitive impairment may avoid some of these poor
outcomes (65–67). Of note, the relationship between
some of these “outcomes” and cognitive impairment may
be bidirectional: there are clear indications that CVD, but
also occurrence of hypoglycemic episodes (68), increase
the risk of developing cognitive impairment in older
patients with diabetes.
Detection and diagnosis
3.2 In patients aged 65 years and older with diabetes,
we suggest that periodic cognitive screening
should be performed to identify undiagnosed
cognitive impairment. (2|��OO)
Technical remark: Use of validated self-administered
51. tests is an efficient and cost-effective way to imple-
ment screening (see text). Alternative screening
test options, such as the Mini-Mental State Ex-
amination or Montreal Cognitive Assessment,
are widely used. An initial screening should be
performed at the time of diagnosis or when a
patient enters a care program. Screening should
be repeated every 2 to 3 years after a normal
screening test result for patients without cogni-
tive complaints or repeated 1 year after a bor-
derline normal test result. Always evaluate
cognitive complaints and assess cognition in
patients with complaints.
Evidence
In the general population, screening for cognitive
impairment and dementia is currently not recommended
because of insufficient evidence on the balance of benefits
and harms of screening (69). This ratio may be different
in people with diabetes because the harm of unrecognized
cognitive impairment (e.g., risks related to diabetes
treatment) might be larger than that in people without
diabetes. The benefit of screening is that this harm might
be at least partially avoided (67). Therefore, an active
approach to the detection of cognitive impairment (i.e.,
screening) has been advocated for older adults with di -
abetes (65, 67). However, the evidence base upon which
screening procedures can be operationalized (i.e., which
target groups, type of test, frequency of testing) is limited.
With regard to the target group, the chance of encoun-
tering cognitive impairment should be sufficiently high to
warrant screening. At this stage, we therefore suggest that
screening should be limited to those over the age of 65
years; in younger patients, actively responding to cog-
nitive complaints should be sufficient.
52. Table 5. Commonly Employed Measures to Screen
for Physical Impairment
Measure Comments
Timed “get-up
and go” test
Most adults can complete this test. Good
correlation with gait speed, Barthel Index,
and measures of balance (47, 48).
4-m Gait speed Robust, clinically friendly measure. Easy to
perform. Can be used to measure
functional status in older adults and to
predict future health and well-being.
Population norms available (49, 50).
Grip strength Requires a dynamometer for objective
measurement; normative ranges in older
people available. Predictive of increased
future functional limitations and disability,
increased fracture risk, and increased all-
cause mortality (51).
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The purpose of screening is to identify marked clini-
cally relevant stages of cognitive impairment (i.e., MCI or
dementia) likely to interfere with diabetes management.
A positive screening test should be complemented by an
appropriate diagnostic evaluation, starting with history
taking, to formally diagnose or rule out these conditions.
With regard to the choice of screening test, brief widely
used tests such as the Mini-Mental State Examination or
Montreal Cognitive Assessment may be suitable, al-
though administering these tests still requires ;10 min-
utes, and currently no strong evidence supports the choice
of one particular test over another (70, 71). Notably, self-
administered cognitive screening tools are becoming
available and might offer an efficient alternative (72),
greatly facilitating widespread implementation.
With regard to the timing and frequency of screening,
performing an initial assessment at the time of diabetes
diagnosis or when a patient enters a care program would
be appropriate. Screening could then be repeated an-
nually, or even less frequently, depending on the per-
ceived risk. In patients without cognitive complaints,
screening should be repeated 2 to 3 years after an initial
normal screening test result or 1 year after a borderline
normal test result. Cognitive complaints should always
be evaluated.
54. Thus far, no evidence supports a benefit of intensive
glycemic treatment to preserve cognitive function in
patients with diabetes (68). However, further trials are
underway, and cognition is increasingly considered an
(secondary) outcome measure in drug trials in diabetes.
Management and treatment
3.3 In patients aged 65 years and older with diabetes
and a diagnosis of cognitive impairment (i.e.,
MCI or dementia), we suggest that medication
regimens should be simplified (see recommenda-
tion 3.1) and glycemic targets tailored (i.e., be
more lenient; see recommendation 4.1) to im-
prove compliance and prevent treatment-related
complications. (2|��OO)
Technical remark: Medical and nonmedical
treatment and care for cognitive symptoms in
people with diabetes and cognitive impairment is
no different from those in people without diabetes
and cognitive impairment. Depending on the
situation and preferences of the patient, a primary
caregiver can be involved in decision-making and
management of medication.
Evidence
No randomized controlled trials (RCTs) have shown
that simplified glucose-lowering treatment regimens
improve adherence in patients with diabetes and cogni-
tive impairment or that tailored glycemic targets reduce
the risk of treatment-related adverse events, particularly
hypoglycemic episodes. However, patients with impaired
cognition are known to have lower adherence and an
increased risk of adverse events (60, 61, 63). Further -
55. more, more stringent control increases the risk of hy-
poglycemia (see “Balancing risks and benefits of lower
glycemic targets” under section 4 on “Treatment of
Hyperglycemia”). Therefore, the assumption that sim-
plifying treatments and tailoring targets improve com-
pliance and prevent treatment-related complications in
patients with impaired cognition is reasonable. HbA1c
levels ,8.0% (64 mmol/mol) have been proposed for
mild-to-moderate cognitive impairment, and those below
8.5% (69 mmol/mol) for moderate to severe cognitive
impairment (66).
With regard to patient care and management in those
with cognitive impairment, regular review of the patient’s
ability to self-manage diabetes and the need for appro-
priate support is essential. Providing support for care-
givers and involving them in all aspects of care are also
important.
4. Treatment of Hyperglycemia
Setting glycemic targets and goals
4.1 In patients aged 65 years and older with diabetes,
we recommend that outpatient diabetes regimens
be designed specifically to minimize hypoglyce-
mia. (1|���O)
Technical remark: Although evidence for specific
targets is lacking, glycemic targets should be tai-
lored to overall health and management strategies
(e.g., whether a medication that can cause hypo-
glycemia is used) (see Table 3).
Evidence
Hypoglycemia has both acute and chronic negative
56. effects on individuals with diabetes in both outpatient
and inpatient settings, although this section pertains to
outpatient practice only (see “Special Settings and Pop-
ulations” for evidence relevant to inpatient care). In the
adult population aged 65 years and older, hypoglycemia
appears to increase the risk of traumatic falls (73–75) and
has a bidirectional relationship with cognitive dysfunc-
tion (see “Cognitive impairment in older adults with
diabetes” under section 3 on “Assessment of Older Pa-
tients with Diabetes”). Hypoglycemia has also been as-
sociated with morbidity and mortality in post hoc
analyses of data from large clinical trials that included
older adults. In one study that analyzed data from the
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Action in Diabetes and Vascular Disease: Preterax and
57. Dimicron Modified Release Controlled Evaluation
(ADVANCE) trial, 231 patients had at least one severe
hypoglycemic episode. Of these patients, most (65%) had
been randomized to the intensive control arm of the trial
(goal HbA1c ,6.5%). The authors reported that severe
hypoglycemia was associated with an approximate
doubling of the adjusted risks of major macrovascular
and microvascular events, death from a cardiovascular
cause and death from any cause (P , 0.001). Severe
hypoglycemia was also associated with other conditions
such as respiratory and gastrointestinal conditions (76).
Although avoidance of hypoglycemia is a critical
treatment strategy, overall glucose control remains an
important goal. Blood glucose levels consistently over the
renal threshold for glycosuria (.200 in chronic hyper-
glycemia, although variable) routinely increases the risk
of dehydration, electrolyte abnormalities, urinary in-
fections, dizziness, and falls. Hyperglycemic crises,
including diabetic ketoacidosis, hyperglycemic hyper-
osmolar syndrome, and the combination of the two
(hyperosmolar ketoacidosis), are severe complications of
unrecognized or undertreated hyperglycemia in older
adults. Older adults with these conditions have higher
mortality rates than do younger individuals (77).
Relaxing glycemic targets for older patients with a high
burden of comorbidities and limited life expectancy may
be appropriate, yet goals that minimize hyperglycemia
are indicated for all patients.
Balancing risks and benefits of lower
glycemic targets
As first noted in the Diabetes Control Complications
Trial (DCCT), achieving a lower mean glucose to reduce
complications may come at the cost of increased hypo-
58. glycemia risk (78). Because prevention of both micro-
vascular and macrovascular disease via glycemic control
may take years to realize, the health value of strict gly-
cemic targets later in life has been controversial. National
and international guidelines that address glycemic targets
generally agree on individualizing care based on overall
health status and weighing the expected timing of ben-
efits against life expectancy (37, 79, 80).
Several studies have illustrated the clinical challenge of
selecting glycemic targets by associating HbA1c achieved
with mortality. One large retrospective analysis from the
United Kingdom associated survival with HbA1c in a
cohort of .40,000 individuals with T2D aged 50 years
or older whose treatment had been intensified beyond
oral monotherapy. The results showed a U-shaped as-
sociation; the adjusted hazard ratios (HRs) of all-cause
mortality were 1.52 (95% CI, 1.32 to 1.76) and 1.79
(95% CI, 1.56 to 2.06) in the groups with the lowest
(median, 6.4%) and highest HbA1c (median, 10.5%)
levels, respectively, compared with the group with a
median HbA1c of 7.5% (81).
A secondary analysis of the Action to Control Car-
diovascular Risk in Diabetes (ACCORD) randomized
trial further highlighted the complexity of targets by
addressing setting vs achieving HbA1c targets. This trial
compared the outcomes of achieving a relatively low
glycemic target of HbA1c ,6.5% with those of achieving
an HbA1c of 7% to 7.9%. Multiple treatment options
were available to providers to achieve glucose goals.
After ;5 years, the intensive treatment group had a 20%
higher rate of mortality, which was significant, and
subsequent analysis of 10,251 subjects enrolled in
ACCORD indicated that the group of subjects who were
59. unable to reach the intensive HbA1c target accounted for
the excess mortality (82). This analysis also demon-
strated that a higher average on-treatment HbA1c was a
stronger predictor of mortality than was a lower HbA1c
and that the risk of death with the intensive strategy
increased linearly from 6% to 9% HbA1c (82). Of note,
the progression of retinopathy was reduced by 30% with
intensive control, although no measurements of func-
tional status were reported for judging the impact on
overall health (83). However, this finding was not
reproduced in the recently published long-term results of
the Veterans Affairs Diabetes Trial (VADT) (84).
Importantly, older individuals enrolled in diabetes
clinical trials are more likely to have better overall health
than are older individuals in the general population.
Numerous studies successfully achieved standard glyce-
mic targets without increased hypoglycemia in older
adults with good or intermediate health (85, 86). Because
these trials exclude older adults with poor health, they
support the concept that intensive strategies for selected
individuals can be effective and safe. The compendium of
results from these and other published analyses suggests
that although some patients may benefit from tighter
targets, many are unable to reach these targets, and
aggressive therapy may be harmful to some patients
without the benefit of reducing complications.
Assessing glycemia in older adults with diabetes
4.2 In patients aged 65 years and older with diabetes
who are treated with insulin, we recommend
frequent fingerstick glucose monitoring and/or
continuous glucose monitoring (to assess glyce-
mia) in addition to HbA1c. (1|��OO)
60. Evidence
Although measurement of HbA1c is a convenient and
validated method for determining overall glycemic status,
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it does not assist in identifying hypoglycemia. In one
study, 40 patients aged 69 years or older with HbA1c
values $8% were evaluated with blinded continu-
ous glucose monitoring (CGM) for 3 days. Most (70%)
had T2D, and nearly all (93%) were treated with insu-
lin. Nearly 75% of subjects experienced a glucose
level ,60 mg/dL despite an elevated HbA1c. Impor-
tantly, of the 102 hypoglycemic episodes recorded, 93%
were unrecognized by symptoms or by fingerstick glucose
measurements performed four times a day (87). Detailed
assessment of glycemia in older adults may also indicate
glycemic variability, which is directly calculated by CGM
61. systems and predicts hypoglycemia in older adults with
T1D (88).
Older adults with T2D also tend to display unique
glucose patterns, with relatively more postprandial hy-
perglycemia than fasting hyperglycemia (89). Knowledge
of such patterns should lead to more tailored and po-
tentially safer medication regimens, for example, adding
premeal insulin to one large meal per day instead of
progressive titration of long-acting basal insulin.
When available, CGM is an important tool for safely
addressing high-risk glycemic patterns. CGM use in older
adults is limited and is variable across populations, in-
cluding patients with T1D, those with T2D, those using
insulin pump therapy, and those using multiple daily
injections of insulin. Clinicians who prescribe CGM for
older adults need to consider many factors, including use
of personal vs intermittent diagnostic CGM, patient se-
lection and individualized goals of CGM, patient access
and affordability, and involvement of family and/or
caregivers in sharing of glucose data. For those older
adults who have been enrolled in clinical trials, CGM
used intermittently or continuously appears to be a useful
tool for guiding therapy to allow improved glycemic
control without increased hypoglycemia. In a clinical
trial by Vigersky et al. (90), individuals with T2D, in-
cluding older adults, were randomized to intermittent
real-time CGM to test the impact on glycemic control.
The population included individuals using various
antihyperglycemic agents, including basal insulin but
excluding prandial insulin. Interestingly, the results in-
dicated that intermittent CGM can assist both patients
and providers in adjusting diabetes regimens to achieve
lower targets without increasing hypoglycemia risk (90).
In the older adult cohort of the DIAMOND study, 116
62. individuals $60 years of age with both T1D and T2D on
multiple daily injections of insulin were randomized to
either personal real-time CGM or to continuation of self-
monitored blood glucose. At the end of 6 months, the
CGM group demonstrated high use (97% of participants
used CGM at least 6 days per week), greater HbA1c
reduction, and less glycemic variability (91).
In addition to its limitations in identifying glucose
patterns, the HbA1c test must be interpreted with cau-
tion, which is particularly significant in older adults given
the increased likelihood of relevant conditions that may
alter red blood cell turnover (e.g., advanced kidney
disease, gastrointestinal bleeding, valvular heart disease).
This topic has been explored in detail by others (92, 93).
Lifestyle interventions for older adults
with diabetes
Lifestyle modifications
4.3 In patients aged 65 years and older with diabetes
who are ambulatory, we recommend lifestyle
modification as the first-line treatment of hy-
perglycemia. (1|����)
Evidence
In overweight patients, lifestyle modifications result-
ing in as little as 5% weight loss can improve glycemic
control and the need for medications to control glucose
levels (94, 95). Nonetheless, older patients face a number
of issues related to nutrition and exercise capacity.
Weight loss should be approached with caution in older
adults, as both intentional and unintentional weight loss
may lead to severe nutritional deficiencies (40). The
63. recommendation of a combination of physical activity
and nutritional therapy, including the recommended
intake of calcium, vitamin D, and other nutrients, is an
appropriate strategy for this population. An increase in
physical activity in older adults should reduce sedentary
behavior, and moderate-intensity aerobic activity should
be emphasized. Moreover, the activity plan must con-
sider the older adult’s abilities and aerobic fitness after
careful medical evaluation, including exercise testing and
heart rate/blood pressure (BP) monitoring as needed.
Activities aimed at increasing flexibility, muscle strength,
and balance are also recommended (96).
Intensive education regarding carbohydrate and cal-
orie counting and meal planning can be useful for in-
dividuals with an active lifestyle to effectively modify
insulin dosing and improve glycemic control (97, 98). A
simpler diabetes meal planning approach emphasizing
portion control and healthful food choices may be more
suitable for older individuals with cognitive impairment
or learning difficulties (99, 100). In the case of sarco-
penia, nutritional therapy coupled with exercise training
is thought to be beneficial.
Nutrition
Nutrition is an integral component of diabetes self-
care for all people with diabetes regardless of age (79,
101). Notably, nutritional guidelines do not differ for
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older adults with or without diabetes. However, older
adults may experience unique challenges that impact
their ability to follow a healthy diet (i.e., finances, buying
food, preparing meals) or have a higher risk of malnu-
trition due to taste and smell alteration, dysphagia, de-
ficient dentition, gastrointestinal dysfunction, anorexia,
cognitive dysfunction, and/or depression (40, 102).
4.4 In patients aged 65 years and older with diabetes,
we recommend assessing nutritional status to
detect and manage malnutrition. (1|����)
Technical remark: Nutritional status can be
assessed using validated tools such as the Mini
Nutritional Assessment and Short Nutritional
Assessment Questionnaire.
Evidence
Many studies support early screening for malnutrition
in older patients, especially those at high risk for mal -
nutrition (acute care-admitted patients and home-care
65. residents) (103, 104). Malnutrition is an important
problem in the older adult population and has potentially
serious consequences, such as prolonged hospitalization,
increased costs, and a higher number of readmissions
(105, 106). Therefore, early detection and management
of malnutrition are crucial for preventing future com-
plications. Moreover, a number of screening tools are
already available to assess nutritional status, and certain
assessments, such as the Mini Nutritional Assessment
and Short Nutritional Assessment Questionnaire, can be
easily administered to older individuals.
4.5 In patients aged 65 years and older with diabetes
and frailty, we suggest the use of diets rich in
protein and energy to prevent malnutrition and
weight loss. (2|��OO)
Evidence
Low-quality studies suggest that consuming energy-
dense and protein-rich food could improve food con-
sumption and prevent weight loss and malnutrition risk.
Approximately 40% of older adults do not meet the
recommended 0.8 g/kg protein intake requirement. The
PROT-AGE study group has recently recommended an
average daily intake in the range of 1.0 to 1.2 g/kg body
weight/d for healthy older people and even 1.2 to 1.5 g/kg
body weight/d in older patients with acute or chronic
diseases. Furthermore, experts have proposed a protein
intake of at least 1.5 g/kg/d (15% to 20% of the total
caloric intake) in sarcopenic or cachectic older in-
dividuals (107). Studies on specific nutrients (protein
supplements, branched-chain amino acids, creatine) have
not shown consistent benefits (108), although the Society
for Sarcopenia, Cachexia, and Wasting Diseases rec-
66. ommends measuring 25-hydroxyvitamin D levels and
replacing them if low in all sarcopenic patients (109).
Nutrition plans for patients with diabetes are generally
individualized healthy diets based on preferences, abili -
ties, and treatment goals. We must emphasize healthful
eating patterns consisting of nutrient-dense, high-quality
foods rather than specific nutrients to improve overall
health regarding body weight; glycemic, BP, and lipid
targets; and reductions in the risk of diabetes compli -
cations (101). The Mediterranean (110), Dietary Ap-
proaches to Stop Hypertension (DASH) (111, 112), and
plant-based (113) diets are all examples of healthful
eating patterns.
Dietary guidelines recommend an increase in fiber
intake of 25 to 35 g/d (114). Choosing vegetables,
legumes, whole grains, and high-fiber breakfast ce-
reals is the best way to increase fiber consumption,
although increasing fiber should be avoided in cases
of delayed gastric emptying (gastroparesis). Addi-
tionally, meeting fluid intake recommendations is im-
portant for preventing constipation and fecal impaction in
older adults (115).
People with diabetes should limit their sodium con-
sumption to ,2300 mg/d. Palatability, availability, af-
fordability, and the difficulty of achieving low-sodium
recommendations in a nutritionally adequate diet are
all important considerations (116). Additionally, older
adults are much more likely to suffer the adverse effects of
alcohol due to changes in their ability to metabolize
alcohol, particularly those taking multiple medications
and those who are at increased risk of adverse events
(117, 118).
67. 4.6 In patients aged 65 years and older with diabetes
who cannot achieve glycemic targets with lifestyle
modification, we suggest avoiding the use of re-
strictive diets and instead limiting consumption of
simple sugars if patients are at risk for malnu-
trition. (2|�OOO)
Technical remark: Patients’ glycemic responses to
changes in diet should be monitored closely. This
recommendation applies to both older adults
living in the community and those in nursing
homes.
Evidence
For nursing home residents, some studies (119–121)
suggest that it is better to use regular diets for nursing
home residents with diabetes. Diets tailored to a patient’s
culture, preferences, and personal goals might increase
quality of life, satisfaction with meals, and nutritional
status (119, 120). Moreover, short-term substitution of
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68. ber 2021
controlled diets with “diabetic diets” was not found to
modify the level of glycemic control (122).
As the most common fluid and electrolyte disturbance
in older adults, dehydration needs to be prevented and
managed in people living in long-term care facilities
(123). Many interventions can reduce its prevalence
(124, 125) in this population and, notably, diuretics and
antihypertensives should be carefully managed after
admission to avoid contributing to fluid and electrolyte
depletion.
For community-dwelling older adults, maintaining a
nutrient-dense diet is essential for promoting health and
preventing nutrition-related complications (126). Evi-
dence indicates that restrictive diets impose significant
risks of sarcopenia and malnutrition in community-
dwelling older adults (127).
Drug therapy for hyperglycemia
Glycemic management of diabetes in
older individuals
Glycemic management strategies must be adjusted to
the individual needs of older patients. Specific factors
regarding certain drug classes are particularly important
for older people with diabetes, especially those with CKD
and heart disease.
4.7 In patients aged 65 years and older with diabetes,
we recommend metformin as the initial oral
69. medication chosen for glycemic management in
addition to lifestyle management. (1|���O)
Technical remark: This recommendation should
not be implemented in patients who have signif-
icantly impaired kidney function [estimated GFR
(eGFR) ,30 mL/min/1.73 m2] or have a gastro-
intestinal intolerance.
Evidence
Metformin is highly effective, may reduce cardio-
vascular events and mortality, and does not cause hy-
poglycemia or weight gain (94, 95, 128, 129). As clinical
events that may precipitate acute kidney injury, such as
radiocontrast dye, nephrotoxic drugs, hypotension, heart
failure, and surgery, may cause metformin accumulation,
with a potential risk for lactic acidosis, metformin use is
often stopped when patients are hospitalized. An addi-
tional concern is the development of vitamin B12 de-
ficiency, and levels should be monitored yearly (130–133).
4.8 In patients aged 65 years and older with diabetes
who have not achieved glycemic targets with
metformin and lifestyle, we recommend that other
oral or injectable agents and/or insulin should be
added to metformin. (1|����)
Technical remark: To reduce the risk of hypo-
glycemia, avoid using sulfonylureas (SUs) and
glinides, and use insulin sparingly. Glycemic
treatment regimens should be kept as simple as
possible.
Evidence
SUs and glinides. SUs, repaglinide, and nateglinide can
70. cause hypoglycemia and weight gain. Glyburide should
be avoided in older individuals because of a substantially
increased risk of hypoglycemia compared with that of
glimepiride and glipizide (130, 131, 134, 135).
Thiazolidinediones. Pioglitazone and rosiglitazone can
cause fluid retention and may precipitate or worsen heart
failure; indeed, these drugs are contraindicated in pa-
tients with class III and IV heart failure (see “Manage-
ment of congestive heart failure in older adults with
diabetes” under section 5 on “Treating Complications of
Diabetes”) (136–138). Furthermore, these medications
are associated with increased fracture rates and bone loss
in women (139, 140); thus, use in older women with
underlying bone disease, such as osteoporosis, could
potentially be problematic.
a-Glucosidase inhibitors. a-Glucosidase inhibitors have
only modest efficacy, and in older individuals, the gas-
trointestinal adverse effects of flatulence and diarrhea tend
to cause a relatively high rate of nonadherence (141).
Dipeptidyl peptidase-4 inhibitors. Dipeptidyl peptidase-
4 (DPP-4) inhibitors are generally well tolerated. Im-
portantly, early concerns regarding an increased risk of
pancreatitis have not been borne out (142, 143), al-
though some DPP-4 inhibitors have been associated with
heart failure (see “Management of congestive heart
failure in older adults with diabetes” under section 5 on
“Treating Complications of Diabetes”).
Sodium-glucose cotransporter 2 inhibitors. Sodium-
glucose cotransporter 2 (SGLT2) inhibitors reduce
HbA1c by ;0.8%, can reduce weight, and do not cause
hypoglycemia. Recently, both empagliflozin and cana-
gliflozin have been shown to decrease major adverse