The document describes rutin extract which is derived from the flower bud of Sophora japonica L. Rutin has various health benefits such as inhibiting platelet aggregation to thin the blood, reducing inflammation, and inhibiting the aldose reductase enzyme. It has functions such as improving circulation, preventing blood clots and strokes, and treating hemorrhoids. The rutin extract being summarized has a 95% rutin content and is sourced from Sophora japonica L. It is used to treat conditions like chronic bronchitis, cerebrovascular disease, and retinal edema.

1. Description of the Rutin Extract
Rutin, also called rutoside, quercetin-3-rutinoside and sophorin, is a citrus flavonoid glycoside
found in the flower bud of Scphora japonica L. Rutin is also present in many other plants and
sometimes referred to as Vitamin P, although not strictly a vitamin.
Rutin inhibits platelet aggregation, as well as decreasing capillary permeability, making the blood
thinner and improving circulation. Rutin has anti-inflammatory activity. Rutin inhibits aldose
reductase activity. Aldose reductase is an enzyme normally present in the eye and elsewhere in the
body. It helps change glucose into a sugar alcohol called sorbitol. Rutin also strengthens the
capillaries, and, therefore, can reduce the symptoms of haemophilia.
Specification of the Rutin Extract
[Product Specification]95% Rutin
[Plant Source Latin Name] Sophora japonica L.
[Test Method] UV-VIS
[CAS NO.] 153-18-4
Functions of the Rutin Extract
1. Rutin inhibits platelet aggregation, as well as decreases capillary permeability, making the
blood thinner and improving circulation. Rutin shows anti-inflammatory activity in some
animal；
2. Rutin inhibits aldose reductase activity. Aldose reductase is an enzyme normally present in the
eye and elsewhere in the body. It helps change glucose into the sugar alcohol sorbitol；
3. Recent studies show rutin could help prevent blood clots, so could be used to treat patients at
risk of heart attacks and strokes；

2. 4. Some evidence also shows rutin can be used to treat hemorrhoids, varicosis, and
microangiopathy；
5. Rutin extract is also an antioxidant; compared to quercetin, acacetin, morin, hispidulin,
hesperidin, and naringin, it was found to be the strongest.
Applications of the Rutin Extract
1. Rutin has a Anti-inflammatory functions , function of Vitamin P , Antivirus effect and restrain
the activity of aldose reductase；
2. It used to prevent stroke, hypertension, retinal hemorrhage, purpura, and acute hemorrhagic
nephritis；
3. The treatment of chronic bronchitis, efficiency reaches 84.8% and 98%；
4. Troxerutin as its derivatives used in the treatment of burns, arthritis & all kinds of vascular
disease, has been the sale of goods abroad；
5. China also produces this drug : the efficiency for cerebrovascular disease 87.8%, cure retinal
edema and bleeding 88%.
Production Details of the Rutin Extract
Qualification of the Rutin Extract

3. FAQ
Packaging
Package: Packed in paper-drums and two plastic-bags inside. 25kg/Fiber Drum,or according to the
needs of customers.
Net Weight:25kgs/drum.
Storage: Stored in a clean, cool, dry area; keep away from strong, direct light.
Shelf Life: Two years when properly stored.