In this report, ISR provides pharmaceutical companies and contract manufacturing organizations a comprehensive analysis of current outsourcing practices and trends, and quantifies CMOs’ service quality across a series of performance attributes. In this Consumer Reports-style analysis, ISR gathered data on 481 service encounters from 116 respondents, all of whom were required to pass screening criteria in order to participate.

1. Contract
Manufacturer Quality
Benchmarking
(2015)
Info@ISRreports.com
©2015 Industry Standard Research www.ISRreports.com
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Report Overview
In this report, ISR provides pharmaceutical companies and contract manufacturing organizations a
comprehensive analysis of current outsourcing practices and trends, and quantifies CMOs’ service quality
across a series of performance attributes. In this Consumer Reports-style analysis, ISR gathered data on
481 service encounters from 116 respondents, all of whom were required to pass screening criteria in
order to participate.
235Charts and Graphs
36CMOs Evaluated
146Pages
481Service Encounters 1. Outsourcing philosophies and practices
2. CMO perceptions and interactions
3. CMO selection drivers
4. CMO performance and scorecards across attributes
5. CMO loyalty
6. Company service quality profiles
7. Study data
8. Respondent Demographics
Valuable for:
Manufacturing, Supply Chain, Brand Managers, Outsourcing/Purchasing, R&D Management, CMO Senior
Management, Sales and Marketing, Business Development, and CMO Operations
How you can use this report:
Drug Developers
• Make a more educated purchase of CMO
services by understanding which CMOs best
fit your company’s needs
• Broaden your CMO evaluation list by
accessing peer-based service performance
reviews across common attributes
• Stay on top of industry trends including
outsourcing models, use of preferred providers,
geographic activities, and outsourcing
propensity across various processes
CMOs
• Improve marketing and proposal content
by understanding key attributes outsourcing
decision-makers are using to drive CMO
selection
• Uncover your own — and competitor —
delivery strengths and weaknesses
• Design messaging that can effectively portray
your company’s strengths and differentiate
from the competition
NEXT: Companies Included
Report Structure:

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Companies Included
ISR received performance ratings on 36 CMOs and 19 are detailed in an in-depth profile.
Companies included:
AbbVie
Aenova
Aesica
Almac
Aptiut
Baxter BioPharma Solutions
BioSpectra
Boehringer Ingelheim
Cambridge Major Labs
Catalent
Cedarburg Hauser
Corden Pharma
DPT
DSM
Evonik
Famar
Fareva
GSK Contract
Manufacturing
Haupt Pharma
Hospira One 2 One
Jubilant Life Sciences
Lonza
LTS
Mylan
NextPharma
NIPRO
Norwich
Patheon
Pfizer CentreSource
Piramal Pharma Solutions
Recipharm
Solvias
Therapure BioPharma
UPM Pharmaceuticals
Vetter
Xcelience

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Table of Contents
Full table of contents and additional sample pages are available on
ISR’s website: http://bit.ly/1JGqkX0

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Introduction
www.ISRreports.com ©2015 | Contract Manufacturer Quality Benchmarking (2015) 7
Introduction
Welcome to ISR’s Contract Manufacturing Quality Benchmarking (2015) report�
Industry Standard Research (ISR) takes pride in our suite of Quality Benchmarking work
and this study is no exception� This report has a wealth of information and has been
created with two very simple goals:
1. Help biopharmaceutical companies make more informed CMO selection
decisions
There are a lot of CMOs out there� Choosing the right one isn’t easy�
There are a lot of questions to be answered� Does the CMO have the capacity to
meet my needs? How is its regulatory track record? Are the staff experienced?
Are timelines met consistently? Performance in these areas is critical, but it isn’t
easy to assess how a CMO will perform without a previous working relationship�
ISR’s study answers these questions� Discover the key attributes that commercial
manufacturing decision-makers are using to drive CMO selection� Learn how
individual CMOs perform along important dimensions� This research affords a
more educated purchase of CMO services and allows readers to narrow down
which CMOs might best fit their needs�
2. Help CMOs optimize operational and marketing strategies
A company can’t fix what it does not know is broken� Perhaps just as importantly,
a company can’t successfully market its strengths if it does not know what aspects
of its performance stand out in the minds of customers� Many CMOs may have an
idea of their customers’ perceptions of strengths and weaknesses, but likely not
with the degree of detail or magnitude provided in this research�
ISR’s Contract Manufacturer Quality Benchmarking report will shed light on how
your customers feel you perform relative to their expectations� This provides an
opportunity to clearly view your company’s strengths through the eyes of your
customers� Messaging and marketing collateral can be designed that effectively
herald your true areas of strength� Comparing your scores to those of your
competition will allow you to differentiate your services based on areas of high
performance�
Consolidation is nothing new to the contract services industry, and a number of
companies featured in the Contract Manufacturing Quality Benchmarking report
(2015) have been part of recent M&A activity� At ISR, we know that integration of a new
acquisition can take a significant amount of time; as such, companies acquired within
the past 18-24 months are still represented by the prior brand name�
Sample Page

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Sample Page
CMO performance and scorecards across attributes
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www.ISRreports.com ©2015 | Contract Manufacturer Quality Benchmarking (2015) 34
Figure 1 – Delivery Factors Ratings
AbbVie
Aesica
Almac
Aptuit
Baxter BioPharma Solutions
Boehringer Ingelheim
Catalent
Corden Pharma
DSM
GSK Contract Manufacturing
Haupt Pharma
Hospira One 2 One
Jubilant Life Sciences
Lonza
NextPharma
Patheon
Pfizer CentreSource
Piramal Pharma Solutions
Vetter
Right first time
measurements
Metrics for
meeting
overall project
timelines
Provides
regulatory
support for
filing
Quality perfor-
mance metrics
Reliable on-time
delivery
Up-front
contingency
planning, risk
management
Flexibility to
adjust schedule
for special
requests
Delivery Factors Ratings
Ratings Key: Clear leadership Better than most About average Falling a bit short Likely deficiency
This sample page comes from the CMO performance and scorecards across attributes section of the
report and is an example of how the CMO performance data is summarized for easy analysis.
Company A
Company B
Company C
Company D
Company E
Company F
Company G
Company H
Company I
Company J
Company K
Company L
Company M
Company N
Company O
Company P
Company Q
Company R
Company S
Right first time
measurements
Metrics for
meeting
overall project
timelines
Provides
regulatory
support for
filing
Quality perfor-
mance metrics
Reliable on-time
delivery
Up-front
contingency
planning, risk
management
Flexibility to
adjust schedule
for special
requests
Delivery Factors Ratings
Ratings Key: Clear leadership Better than most About average Falling a bit short Likely deficiency

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Sample Page
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Company service quality profiles
www.ISRreports.com ©2015 | Contract Manufacturer Quality Benchmarking (2015) 43
0 2 4 6 8 10
Industry Average
AbbVie 7.0
6.6
0.00 0.00
0.20
-0.20-0.20
0.27
0.13
-0.13
0.07
-0.07
0.33
0.20 0.27
-0.13 -0.20-0.20
0.33
0.20
-0.20-0.27-0.27
0.33
-0.13 -0.20
-0.40
0.27
-0.27
-0.53
-1.50
-1.00
-0.50
0.00
0.50
1.00
1.50
AbbVie Familiarity
AbbVie Use
AbbVie Loyalty
AbbVie (N=15)
Strengths:
Full range of
manufacturing
for parenteral
dosage forms
Offers innovative
solutions
Scientific
knowledge
Weaknesses:
Strong regulatory
track record
Well-regarded
within the
industry
Highlights
Company Profiles — AbbVie
© Industry Standard Reseach
www.isrreports.com
©2015|Contract
Manufacturer
Quality
Benchmarking
(2015)
45
Kelly Profiles
Relative Strengths and Weaknesses for Profiles:
AbbVie
o Strengths:
! Full range of manufacturing for parenteral dosage forms
! Offers innovative solutions
! Scientific knowledge
o Weaknesses:
! Strong regulatory track record
! Well-regarded within the industry
10% 17% 32% 28% 12%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
I have used this company’s commercial manufacturing services
I am very familiar with this company’s commercial manufacturing services but have not used them
I am somewhat familiar with this company’s commercial manufacturing services but have not used them
I am aware of this company but know nothing about its commercial manufacturing services
9% 3% 9% 78%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
Currently using Used in the past 18 months Used more than 18 months ago Never used
CMO familiarity
CMO use
n = 15
Industry Average = 6.6
Loyalty Score = 7.0
www.isrreports.com
©2015|Contract
Manufacturer
Quality
Benchmarking
(2015)
45
Kelly Profiles
Relative Strengths and Weaknesses for Profiles:
AbbVie
o Strengths:
! Full range of manufacturing for parenteral dosage forms
! Offers innovative solutions
! Scientific knowledge
o Weaknesses:
! Strong regulatory track record
! Well-regarded within the industry
10% 17% 32% 28% 12%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
I have used this company’s commercial manufacturing services
I am very familiar with this company’s commercial manufacturing services but have not used them
I am somewhat familiar with this company’s commercial manufacturing services but have not used them
I am aware of this company but know nothing about its commercial manufacturing services
9% 3% 9% 78%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
Currently using Used in the past 18 months Used more than 18 months ago Never used
CMO familiarity
CMO use
n = 15
Industry Average = 6.6
Loyalty Score = 7.0
www.isrreports.com
©2015|Contract
Manufacturer
Quality
Benchmarking
(2015)
45
Kelly Profiles
Relative Strengths and Weaknesses for Profiles:
AbbVie
o Strengths:
! Full range of manufacturing for parenteral dosage forms
! Offers innovative solutions
! Scientific knowledge
o Weaknesses:
! Strong regulatory track record
! Well-regarded within the industry
10% 17% 32% 28% 12%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
I have used this company’s commercial manufacturing services
I am very familiar with this company’s commercial manufacturing services but have not used them
I am somewhat familiar with this company’s commercial manufacturing services but have not used them
I am aware of this company but know nothing about its commercial manufacturing services
9% 3% 9% 78%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
Currently using Used in the past 18 months Used more than 18 months ago Never used
CMO familiarity
CMO use
n = 15
Industry Average = 6.6
Loyalty Score = 7.0
www.isrreports.com
©2015|Contract
Manufacturer
Quality
Benchmarking
(2015)
45
Kelly Profiles
Relative Strengths and Weaknesses for Profiles:
AbbVie
o Strengths:
! Full range of manufacturing for parenteral dosage forms
! Offers innovative solutions
! Scientific knowledge
o Weaknesses:
! Strong regulatory track record
! Well-regarded within the industry
10% 17% 32% 28% 12%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
I have used this company’s commercial manufacturing services
I am very familiar with this company’s commercial manufacturing services but have not used them
I am somewhat familiar with this company’s commercial manufacturing services but have not used them
I am aware of this company but know nothing about its commercial manufacturing services
9% 3% 9% 78%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
Currently using Used in the past 18 months Used more than 18 months ago Never used
CMO familiarity
CMO use
n = 15
Industry Average = 6.6
Loyalty Score = 7.0
AbbVie Average Customer Experience
Somewhat
Exceeds
Expectations
Somewhat
Misses
Expectations
I have used this company’s commercial manufacturing services
I am very familiar with this company’s commercial
manufacturing services but have not used them
I am somewhat familiar with this company’s commercial
manufacturing services but have not used them
I am aware of this company but know nothing about its
commercial manufacturing services
I have never heard of this company
This sample page comes from the Company profiles section of the report and is an example of the
analysis for each of the 19 CMOs profiled in this report.
Sample Company
Sample Company

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Sample Page
Full table of contents and additional sample pages are available on
ISR’s website: http://bit.ly/1JGqkX0

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tries. With over a decade of experience in the industry, ISR delivers an unmatched level of domain expertise.
For more information about our off-the-shelf intelligence and custom research offerings, please visit our Web site at
www.ISRreports.com, email info@ISRreports.com, or follow us on twitter @ISRreports.
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