This MBA Thesis presentation looks at pharmacist-led programs that not only improve patient outcomes, but help save millions by preventing medication errors, thirty-day hospital readmissions, and medication-induced morbidity and mortality.
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Focusing on Pharmacist-Led Programs to Improve Medication Management Produces Significant Savings
1. Focusing on Pharmacist-Led
Programs to Improve Medication
Management Produces Significant
Savings
HEIDI YANOSKI
WILKES UNIVERSITY PHARM.D, MBA CANDIDATE, 2017
MBA THESIS PRESENTATION
5. What’s the Problem?
1001
665
328
173 163 124 92 92 62 51
0
200
400
600
800
1000
1200
Healthcare Expenditures in 2016
Cost ($ billion)
32
20
10
5
5
4
3
3
2
2
2016 Market Spread (%)
Hospital PCP/Clinical
RX Drugs Personal Care
Nursing Home Dental
Home Health Other
Non-Durable Equipment Durable Equipment
Healthcare costs and spending have risen dramatically
6. What’s the Problem?
50% of Americans suffer from one chronic illness
3.2 billion prescriptions ordered during PCP visits
1.5 million medication errors annually
Thirty-day hospital readmissions cost $15 billion
7. What’s Been Done?
The Affordable Care Act of 2010
Positive influence on the US economy
Prominent goal is healthcare spending
reduction
30-day readmissions and preventable
readmissions reduced
9. Transitions of Care (TOC)
Definition
“The movement of patients between health care locations, providers, or different
levels of care within the same location as their conditions or care needs change.”
Highly-error prone and poorly managed
66% of all medication errors occur during a care transition
$3.5 billion annual costs
10. TOC Studies
Small
Mission Hospital, North Carolina
384-patient intervention cohort
9 month study period
Savings
ROI
Medium
Kaiser Permanente Colorado Health
System
Skilled Nursing Facility to home
Hospital to home
521 patient experimental group
6 month study period
Savings
Large
State of Hawaii
2083 intervention patients
2 year study period
Medication-related hospitalizations
Savings
ROI
12. Medication Therapy
Management
Definition
“Service or group of services that optimize
therapeutic outcomes for individual patients.”
Medication errors cause morbidity and
mortality
$177 billion in additional costs
MTM clinics rising in popularity
13. MTM Studies
Diabetes
Geisinger
1875 patients
8 year study
Total cost savings
Cholesterol
Floridian Medicare patients
255 diabetic patients
21 month study
Projected savings
Long-Term Care
North Carolina Long-Term Care
Polypharmacy Initiative
5255 members
Total savings
19. Cost-Benefit Analysis
Definition
“A form of economic analysis from a social perspective, in which the costs of
medical care are compared with the economic benefits of the care provided, with
both the costs and benefits being expressed in monetary units.”
Important for payors to determine which drugs should be placed on formulary
20. Entresto Cost-Benefit Analysis
Entresto (valsartan/sacubitril)
PARADIGM Trial projection
Added 1 quality life year
3000 avoided hospitalizations annually
$27 million saved annually
21. Recommendations
Savings of all studies examined = $53.1 million annually
ACA has shown real benefit
Numerous studies in each section proves pharmacist efficacy
Continue research to find best way to expand
Important step is looking further into insurance companies
Already found the savings potential, let’s continue
23. References
APhA, A. P., & NACDS, N. A. (2008). Medication Therapy Management in Pharmacy Practice: Core Elements of an MTM Service Model. Retrieved
December 3, 2017, from http://www.pharmacist.com/sites/default/files/files/core_elements_of_an_mtm_practice.pdf
Centers for Disease Control and Prevention. (2017, May 3). Therapeutic Drug Use. Retrieved September 20, 2017, from National Center for Health Statistics:
https://www.cdc.gov/nchs/fastats/drug-use-therapeutic.htm
Centers for Medicare & Medicaid Services. (2016). Evidence Supporting Enhanced Medication Therapy Management. Center for Medicare and Medicaid
Innovation. Retrieved November 20, 2017, from https://innovation.cms.gov/Files/x/mtm-evidencebase.pdf
Centers for Medicare and Medicaid Services. (2014). Affordable Care Act. Retrieved July 18, 2017, from Medicaid.gov:
https://www.medicaid.gov/affordable-care-act/index.html
Cost-effectiveness Analysis of Sacubitril/Valsartan vs Enalapril in Patients With Heart Failure and Reduced Ejection Fraction. (2016, June 22). Journal of the
American Medical Association Cardiology. Retrieved July 31, 2017, from
file:///C:/Users/Heidi/Downloads/SV%203%20Cost%20Effectiveness%20of%20SacubitrilValsartan%20in%20US.pdf
Dieleman, J., Baral, R., Birger, M., & al., e. (2016). US Spending on Personal Health Care and Public Health, 1996-2013. The Journal of the American
Medical Association, 316(24), 2627-46. Retrieved July 18, 2017, from http://jamanetwork.com/journals/jama/fullarticle/2594716
Fox, D., Ried, L., Klein, G., Myers, W., & Foli, K. (2009, Mar-Apr). A medication therapy management program's impact on low-density lipoprotein
cholesterol goal attainment in Medicare Part D patients with diabetes. Journal of the American Pharmacist's Association, 49(2), 192-9. Retrieved November
20, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/19289345
Gaziano, T. A., Fonarow, G. C., Claggett, B., & al., e. (2016, September). Cost-effectiveness Analysis of Sacubitril/Valsartan vs Enalapril in Patients With
Heart Failure and Reduced Ejection Fraction. Journal of the American Medical Association Cardiology, 1(6), 666-672. Retrieved September 20, 2017, from
Cost-effectiveness Analysis of Sacubitril/Valsartan vs Enalapril in Patients With Heart Failure and Reduced Ejection Fraction
Jones, L., Greskovic, G., Grassi, D., & al., e. (2017, September). Medication therapy disease management: Geisinger’s approach to population health
management. American Journal of Health-System Pharmacists , 74(18), 1422-1435. Retrieved November 20, 2017, from
http://www.ajhp.org/content/74/18/1422
24. References, Continued
Kim, W. C., & Mauborgne, R. (2004, October). Blue Ocean Strategy. Harvard Business Review, 76-84. Retrieved September 20, 2017, from
https://hbr.org/2004/10/blue-ocean-strategy
Maeng, D., Yan, X., Graf, T., & Steele Jr., G. (2016, March). Value of Primary Care Diabetes Management: Long-Term Cost Impacts. The American
Journal of Managed Care, 22(3), 88-94. Retrieved July 18, 2017, from
https://ajmc.s3.amazonaws.com/_media/_pdf/AJMC_03_2016_Maeng%20(final).pdf
Manolakis, P. G., & Skelton, J. B. (2010, December 15). Pharmacists' Contributions to Primary Care in the United States Collaborating to Address Unmet
Patient Care Needs: The Emerging Role for Pharmacists to Address the Shortage of Primary Care Providers. American Journal of Pharmaceutical
Education, 74(10). Retrieved September 20, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058447/
National Committee to Preserve Social Security and Medicare. (2017). Fast Facts About Medicare. Retrieved July 18, 2017, from NCPSSM:
http://www.ncpssm.org/Medicare/MedicareFastFacts
National Transitions of Care Coalition. (2017). About NTOCC. Retrieved September 20, 2017, from NTOCC.org: http://www.ntocc.org/aboutus.aspx
Schoen, C. (2016, February ). The Affordable Care Act and the US Economy: A Five-Year Perspective. The Commonwealth Fund. Retrieved July 18,
2017, from http://www.commonwealthfund.org/~/media/files/publications/fund-report/2016/feb/1860_schoen_aca_and_us_economy_v2.pdf?la=en
Sen, S., Bowen, J. F., Ganestsky, V. S., & al., e. (2014, September 4). Pharmacists implementing transitions of care in inpatient, ambulatory and
community practice settings. Pharmacy Practice, 12(3), 508. Retrieved September 20, 2017, from
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161412/
Trygstad, T., Christensen, D., Wegner, S., SUllivan, R., & Garmise, J. (2009, September 31). Analysis of the North Carolina long-term care polypharmacy
initiative: a multiple-cohort approach using propensity-score matching for both evaluation and targeting. Clinical Therapy, 31(9), 2018-37. Retrieved
November 20, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/19843492
Editor's Notes
Healthcare costs and spending have risen dramatically
Hospital care – 32% share with $1.1 trillion spent
Physicians and clinical services – 20% with 664.9 billion
Prescription drugs – surprisingly only hold only 10% of the market with $328 billion in costs
Residential and personal care services – any type of rehabilitation stays or assisted living apartment complexes
Nursing home care –
Dental
Home health – includes rehab at home, wound changing, IV infusion services
Other – clinical services provided by independent practitioners such as PT, OT, optometry, podiatry, or chiropractors.
Non-durable medical equipment includes eyeglasses, hearing aids, contact lenses, etc.
Durable medical equipment includes OTC medications, medical or surgical instruments, dressings, canes, crutches, wheelchairs, etc.
The average growth for all these market sectors was 4.22%, with the highest growth in the PCP and Clinical sector at 5.4%, and the lowest, surprisingly, in the pharmaceuticals, which only grew 1.3% in 2016. This was a large change from 2014 and 2015, when the market grew 12.4% and 8.9%, respectively.
50% of Americans suffer from one chronic illness
3.2 billion prescriptions ordered during PCP visits
1.5 million medication errors annually
Thirty-day hospital readmissions cost $15 billion
The Affordable Care Act (ACA) accounts for two separate pieces of legislation, the Patent Protection and Affordable Care Act and the Health Care and Education Reconciliation Act of 2010, that have been working to expand public health care coverage since it was enacted in March of 2010
Positive influence on the US economy since the 2008 housing bubble recession
The US has gained over 14 million new full-time jobs since 2010
5 million more people working now
Dramatic decrease on the US unemployment rate, which is 4.1% as of October 2017, compared to October 2009, right before the act was signed into law, at 10%
Prominent goal is healthcare spending reduction
Incentivized providers to achieve better outcomes at a lower cost
30-day readmission plan, institutions where patients are readmitted after 30 days due to the provision of sub-standard care will not be compensated for their services
Early participants in the program achieved savings of $385 million in 2012 and 2013
Medicare admissions for preventable conditions decreased by 25% and 30-day readmission rates fell 17%
Placed an emphasis on primary care
Small
Mission Hospital, North Carolina
384-patient intervention cohort
9 month study period
Primary endpoint was thirty day readmissions, decreased by 50.2%
Results unchanged when adjusted for age, race, gender, and number of disease states
Increased validity of study
ED admissions also significantly reduced (51%) and sustained at 30, 90, and 365-day period
Mean direct cost of a 30-day readmission was $4306
Translated to a $189,464 reductions in utilization at thirty days, and $786,529 annual savings.
ROI at 30 days was $12 saved for every $1 invested in pharmacist time, positively sustained through 365 days
Medium
Kaiser Permanente Colorado Health System has a network of hospitals and skillet nursing facilities, and insurance
Two groups in the study
Skilled Nursing Facility to home
Hospital to home
521 patient experimental group
After completing the programs, patients were 78% less likely to die, 29% less likely or need an ER visit, and 17% more likely to follow up with PCP clinicians
Savings
Average decrease in $9974 in total costs per patient annually
Pharmacy utilization costs were significantly increased after enrollment, which was offset by the significant savings in inpatient professional services
Annualized cost savings per patient was $5276, which turned out to be $4 million in savings in 2003
Large
Conducted throughout the state of Hawaii at 6 different experimental and 5 different control hospitals
Looked at 2083 patients over two years ONLY admitted for medication related problems as determined by pre-chosen ICD-9 codes
Decreased admissions by 36%
Approximately 394 hospitalizations would be avoided annually
Amount to an average annual savings of 6.6 million, with a net annual savings of 4.8 million.
Pharmacist services cost 1.8 million
264% return on investment
Diabetes
Large initial increase in costs due to patients seeing pharmacists more and being prescribed more medications or more expensive medications
Total estimated cost savings associated with any DSC exposure was $47 per member per month and $89 PMPM savings in inpatient costs, (9 pmpm output fees = 2 pmpm in professional fees) which yields approximately $2.8 million in savings annually for 1875 patients – as more patients are enrolled, more savings will be generated.
Cholesterol
After one year, more than two thirds of these patients reached their cholesterol goals
This group, after the 21 months, used less medications to treat their conditions than the control group
Florida has approximately 3 million Medicare Part D enrollees, and based on the savings in the study, it would be projected to save $12 million
Long-term care
Looked at pharmacist-provided MTM services in order to reduce polypharmacy, or drugs used to treat side effects of another medication, or two drugs of the same mechanism.
Looked at seniors living in long-term care homes.
Cost-savings od $21.63 per member per month in drug cost savings was observed, yielding $1.3 million in savings annually
JAMA conducted a retrospective study published in 2016 looking at medical claims (government programs, insurance claims, facility surveys, and household surveys)
This was in terms of aggregate disease states, in which ischemic heart and cerebrovascular disease (excluding HTN and HLD tx) were the costliest personal healthcare expenditure, accounting for over $231 billion spent from 1996-2013.
Diabetes was not far behind.
This table shows the top ten conditions in which the most personal health care expenditures went towards
However, in terms of individual disease, diabetes was number one at 101.4 billion spent
Ischemic heart disease was right behind at 88.1 billion spent
Cardiovascular
Entresto (valsartan/sacubitril)
Used to treat heart failure
PARADIGM Trial projection
3000 avoided hospitalizations annually
Added 1 quality life year
Savings of $27 million annually