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NeoGenomics
Company Overview Presentation
June 2017
2
Forward-looking Statements
This presentation contains statements which constitute forward-looking statements within the
meaning of Section 27A of the Securities Act, as amended; Section 21E of the Securities Exchange
Act of 1934; and the Private Securities Litigation Reform Act of 1995. The words “may”, “would”,
“could”, “will”, “expect”, “estimate”, “anticipate”, “believe”, “intend”, “plan”, “goal”, and similar
expressions and variations thereof are intended to specifically identify forward-looking
statements. All statements that are not statements of historical fact are forward-looking
statements.
Investors and prospective investors are cautioned that any such forward-looking statements are
not guarantees of future performance and involve risks and uncertainties, and that actual results
may differ materially from those projected in the forward-looking statements as a result of various
factors. The risks that might cause such differences are identified in our filings with the Securities
and Exchange Commission. We undertake no obligation to publicly update or revise the forward
looking statements made in this presentation to reflect events or circumstances after the date of
this presentation or to reflect the occurrence of unanticipated events.
3
Investment Highlights
Leading pure-play oncology testing company
Unique client partnership business model
History of strong clinical growth & rapid innovation
Favorable demographics driving expanding market
Increasing momentum in Pharma Services
Realization of Clarient cost synergies accelerating
Significant opportunities for market share gains and
Adjusted EBITDA expansion
4
Financial Facts
NASDAQ Ticker: NEO
Stock Price (6/5/17): $7.78
Basic Shares Outstanding: 79.2 MM
Avg. Daily Volume (3 Mos.): 372K
52 Week Low/High: $6.90/9.88
% Held by Insiders: 17.5%
Market Cap (6/5/17) $616.5 MM
Debt (MRQ) 111.0
Preferred Stock (Redemption Value) 46.6
Less Cash (MRQ) (11.0)
Enterprise Value $763.1 MM
EV/ 2017 Consensus Rev 2.9x
Recent Financial Performance
($,MMs)
Recent Financial Performance FY 2016
YoY
% Chg. *
Clinical Testing Rev $222.0 124%
Pharma Service Rev 22.1 1,728%
Total Revenue 244.1 145%
Adjusted EBITDA $34.7 259%
% EBITDA Margin 14.2% +450bps
* % Change includes the effects of Clarient Acquisition.
Stock Information Market Capitalization & Enterprise Value
2016 Financial Highlights5 Year Stock Price Performance
5
Proven Management Team
• Combination of industry-experienced medical, financial and technical professionals
• Integral role in the Company’s industry leading operating model and unrivaled growth trajectory
• Instrumental to the successful integration of the Clarient Acquisition
Position NEO Experience Industry Experience
Douglas VanOort Chief Executive Officer 8 years 35 years
Maher Albitar, M.D. SVP & Chief Medical Officer 5 years 26 years
Robert Shovlin President of Clinical Services Division 3 years 20 years
Steven Jones Executive Vice President 15 years 15 years
George Cardoza SVP & Chief Financial Officer 8 years 23 years
Jennifer Balliet Chief Culture Officer 9 years 9 years
Steven Ross Chief Information Officer 3 years 3 years
Denise Pedulla General Counsel 2 years 21 years
Bill Bonello Vice President, Treasurer & Dir. of Corp. Dev. <1 year 10 years
Steven Brodie, Ph.D., FACMG Vice President of Operations 8 years 14 years
Fred Weidig
Vice President, Finance & Principal
Accounting Officer
10 years 10 years
NEO’s Proven Track Record of Consistent Growth
Clinical Genetic Testing Annual Revenue Clinical Genetic Tests Performed
($, 000s)
* Base NEO represents organic revenue and test volume growth from legacy business and excludes the impacts from the PathLogic and Clarient acquisitions.
6
$558 $1,885
$6,476
$11,505
$20,015
$29,469
$34,371
$43,484
$59,866
$66,467
$82,194
$188,374
$214,708
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
Pro Forma Clarient 2015 Genetic Test Revenue
NEO Clinical Genetic Testing Revenue
1,152
4,082
12,838
20,998
32,539
45,675
57,332
76,288
114,606
137,317
177,279
490,450
563,132
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
Pro Forma Clarient 2015 Clinical Genetic Tests
NEO Clincial Genetic Tests Performed
7
Growth Goals
• Mid-teens organic clinical volume growth
• 20%+ organic Pharma revenue growth
• 25-35% incremental Adj. EBITDA on revenue growth
Driven by:
− Comprehensive test menu – “One-Stop Shop”
− Innovation in test development
− Demographics and medical advances
− Increased efficiencies
Strong Track Record of Innovation
Leader in FISH, Flow Cytometry, IHC, Molecular, Immuno-Oncology
(PD-L1) and Emerging Leader in Liquid Biopsy Testing!
70 new/revised tests, incl:
NeoLABTM Liquid Biopsies
• MDS/CMML Profile
• AML Profile
• FLT3 Mutation Analysis
• NPM1 Mutation Analysis
• PML-RARA Translocation
• RUNX1-RNX1T1Transloc
• INV16 Translocation
• c-kit Mutation Analysis
• IDH1 Mutation Analysis
• IDH2 Mutation Analysis
• NRAS Mutation Analysis
• KRAS Mutation Analysis
• BTK Inhibitor Resistance
• Solid Tumor Monitoring
Germline MolDx Testing
• BRCA1 & BRCA2
• Lynch Syndrome (colon)
• 73 Gene Comprehensive
Predisposition Panel
Other
• ALK, ROS1, RET Fusion
• Sarcoma gene Fusion
• NeoSITE Cervical FISH
• Expanded IHC Menu
• Smart Flow Cytometry
• 10-color Flow Cytometry
• Implemented Adv MolDx
platform in lieu of Kits
• 28 new Molecular Assays
• Proprietary method for
increasing sensitivity of Sanger
sequencing
• 7 NeoTYPE MolDx Panels
• SVM for FISH (Patent App)
• Barrett’s Esoph. FISH (Patent
App)
• NeoARRAY/SNP Cytogenetics
• Internalized send-outs
40 new Molecular tests, incl:
• Add’l NeoTYPE Panels
• Next Generation
Sequencing (48 genes)
• ROS1 FISH
• NeoSITE Melanoma FISH
• Plasma/Urine-based Prostate
Test (Patent App)
• SVM-based Cytogenetics
Analysis System
• SVM-based Automated FISH
Analysis System v2
• Began development of
NeoLAB (Liquid Alternative
to Biopsy) Prostate Cx test
60 new/revised tests, incl:
• 24 new NeoTYPE Next
Generation Sequencing
Profiles
• 26 new IHC/ISH tests
• Additional NeoLAB Prostate
clinical studies
• AML Extended FISH Panel
• AML Favorable-Risk FISH Panel
• MDS Extended FISH Panel
• Plasma Cell Myeloma Risk
Stratification FISH Panel
• RET FISH
• MET FISH
• ALL Adult & Pediatric FISH
Panels
• HER2 Breast Equivocal FISH
Panel
• BRAF Translocation FISH
• Chromosome 1 POC Ploidy
• Launched robotic FISH-Cyto
processing platform
50 new/revised tests, incl:
• Comprehensive PD-L1 Testing
(three FDA-cleared and one LDT)
• 1,385 genes RNA-Based Pan
Cancer NGS Fusion, Mutation
and Expression Profiling.
• Smart Flow Cytometry data
analysis platform
• Pediatric Hereditary Susceptibility
• Hereditary DNA Panel (prostate)
• Inherited Bone Marrow Failure
• MET Exon 14 Deletion Analysis
• NRAS Exon 4 Mutation Analysis
• NGS ALK, NTRK, RET, ROS1 Fusion
NeoLABTM Liquid Biopsies
• NeoLAB Myeloid Disorders Profile
• EGFR T790M
NeoTYPETM Multi Modality Profiles
• AITL/Peripheral T-Cell Lymphoma
• Thyroid Profile
• Brain Tumor Profile
• Melanoma Profile
• Liposarcoma Fusion Profile
• Head & Neck Tumor Profile
FISH & IHC
• FISH Testing for EWSR1, SS18,
DDIT3, STAT 6, BCL2, & TCL1
• IHC Testing for CXCL13, BAP1,
INI1, MUC4
• PD-LI
2012
2013
2014
2015
2016
8
Positive Demographic Tailwinds and ….
Shifting Demographics Incidence of Cancer by Age
0.0
20.0
40.0
60.0
80.0
100.0
120.0
Age 60-64 Age 65-74 Age 75-84 Age 85+
1.0%
2.7%
5.1%
13.8%
24.4%
26.2%
18.8%
7.9%
< 20 20-34 35-44 45-54 55-64 65-74 74-84 > 84
Source: United States Census Bureau Source: National Cancer Institute
9
Rapidly Growing Market Opportunity
Source: National Institutes of Health (NIH)
10
• Aging Population –
incidence increases with age
• Increased Prevalence –
better treatments lead to
more survivors and
monitoring
• Scientific advances – driving
targeted therapeutics
• Increased cost of drugs –
more careful triage and
monitoring
Positions NEO for Additional Market Share Gains
11
• Based on CMS Data, the Cancer
Market was $5.1B in 2014
• Assuming modest growth, the
Cancer Market is about $6B in 2017
• NeoGenomics 2017 Revenue
estimate of $260M --- about 5% of
the market
• Industry is highly fragmented – and
is expected to consolidate further
over time
Opportunities by Customer Type
Pathologists & Hospitals (about 80% of Revenue)
• Large Market with 5,600 Hospitals in U.S., and 18,000 active Pathologists
• Enable Pathologists to practice using sophisticated tools/tests and “tech-only” services
• Unique ability to be “One-stop shop” with comprehensive oncology test menu
• Competitive pricing under contract, and agreements with hospitals & hospital GPOs
Oncologists, Hematologists & Clinicians (about 10% of Revenue)
• Disease Panels, liquid biopsies, and comprehensive molecular menus
• Increasing opportunity to service larger practices with Partnership-based tech-only model
• Contracts with key Managed Care organizations
Pharma Services & Other (about 10% of Revenue)
• Contract research/clinical trial support work for Pharma clients
• Opening in Geneva, Switzerland to handle European and Global studies
• MultiOmyx platform is a unique offering gaining acceptance by Pharma firms
12
Evolution of Payer Mix For Clinical Testing
Medicare reimbursements have fallen from 52% of payer mix in 2010 to 16% in 2016!
(1) 2016 is a blended average estimate of the Base NEO and Clarient payer mixes.
13
52%
44%
37%
27%
21% 21%
16%
23%
26%
34%
45%
51%
59%
58%
23%
29% 28% 28% 29%
20%
26%
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
2010 2011 2012 2013 2014 2015 2016
Medicare (Incl. Medicaid) Client Bill (Hospitals) Commercial Insurance Other/Accruals/Pt. Pay
(1)
Accelerating Improvements in Cost per Test
14
15
Historically Steady Margins Despite Lower Avg. Unit Prices*
* To facilitate comparison, all data is for Clinical Genetic Testing and excludes the impact from the PathLogic acquisition and Pharma Services.
(1) Productivity calculated as the average number of lab tests completed per month per laboratory FTE.
45.9%
44.7%
44.8%
47.7% 48.0%
46.1%
47.2%
-40.9%
65.6%
-50%
-40%
-30%
-20%
-10%
0%
10%
20%
30%
40%
50%
60%
70%
35%
40%
45%
50%
55%
2010 2011 2012 2013 2014 2015 2016
Gross Margin % From Clinical Genetic Testing Cum Change in Avg Rev/ Clinical Genetic Test Since 2009
Cum Change in Productivity Since 2009
CumChangeinAvgRev/Test&Productivity
(1)
Clarient Cost Synergies and Opportunities
16
2015 Adjusted EBITDA
NeoGenomics $ 9.7 MM
Clarient Pro Forma $ 9.2 MM
Pro Forma Combined $18.9 MM
2016 “New Neo” EBITDA $ 34.7 MM
Clearly, “synergies” showed up in 2016 --- and there are more to be realized in 2017- 18
2017 – 2018 Opportunities:
• Laboratory facilities consolidated on 3/26/17 – teams now working as one
• Ability to run combined batches in So. California rather than two batches
• Ongoing supplier re-negotiations as contracts end – we have 2x volume
• Irvine laboratory closed on 4/30 – saving over $50k per month
• Cross selling now possible – accounts all on one laboratory information system
• Pharma services just starting to access Neo’s leading Molecular menu
“9 + 9 equals 34”
Growing Pharma Services
$41.6mm Backlog as of 3/31/17 - Approx. 400 active projects from 100+ Clients
• 50% of projects in pre-clinical space – often leading to more lucrative Phase I, II, and III work
• Major PD-L1 testing site for Keytruda (Merck) and Opdivo (BMS) – Leader in Immuno-Oncology
• Medical and Scientific expertise, comprehensive test menu, & extensive clinical network
• International presence in 2017 with Geneva, Switzerland Lab
17
18
Pharma Services Revenue & Backlog
$5.1
$6.8
$5.0 $5.2 $5.0
$23.7
$26.0
$33.0
$36.8
$41.6
$0
$10
$20
$30
$40
$50
Q1'16 Q2'16 Q3'16 Q4'16 Q1'17
Revenue Backlog
($, MMs)
Recent Financial Information (P&L)
($, 000's) 2014(1) 2015(2)(3) 2016(3) Q1 2016 Q1 2017(4)
Total Revenue $ 87,069 $ 99,802 $ 244,083 $ 59,704 $ 61,676
% Growth (YoY) 31.0% 14.6% 144.6% 159.3% 3.3%
Total Gross Profit 40,714 43,756 110,379 27,173 27,196
Gross Margin % 46.8% 43.8% 45.2% 45.5% 44.1%
Total SG&A (Incl R&D) Exp(3) 38,496 49,391 107,804 25,251 27,311
SG&A as a % of Rev 44.2% 49.5% 44.2% 42.3% 44.3%
Adjusted Net Income/(Loss)* 2,689 4,042 14,399 $ 2,884 $ 2,552
Adjusted Diluted EPS* $0.05 $0.06 $0.15 $0.03 $0.03
Adjusted EBITDA* $ 9,176 $ 9,672 $ 34,685 $ 8,236 $ 7,070
% Growth 7.8% 9.7% 258.4% 442.2% -14.2%
Operating Data(5)
% Growth in Clinical Genetic Tests (YoY) 29.1% 25.6% 154.6% 174.7% 15.3%
Avg. Revenue/Clinical Genetic Test $ 464 $ 412 $ 381 $ 391 $ 354
% Change (YoY) -4.2% -11.2% -6.8% -6.1% -9.4%
Avg. COGS/Clinical Genetic Test $ 241 $ 220 $ 201 $ 206 $ 186
% Change (YoY) -4.7% -8.6% -8.7% -12.7% -9.7%
* See Appendix for definitions of Adj. EBITDA, Adj. Net Income and Adj. Diluted EPS as well as a reconciliation of GAAP Net Income to Adjusted financial information.
(1) 2014 figures include the results of PathLogic from the date of the acquisition on July 8, 2014.
(2) 2015 figures include the results of Clarient for two days from the date of the acquisition on December 30, 2015 and $4.7 MM of Clarient transaction expenses in SG&A.
(3) 2016 SG&A includes 7.4 MM of one-time bank debt retirement fees and impairment charges.
(4) Q1 2017 SG&A includes $0.4 MM of one-time expenses associated with the move of NeoGenomics Irvine, CA facility into its Aliso Viejo, CA facility.
(5) All Operating data refers to Clinical Genetic Testing and excludes the results from PathLogic and the Pharma Services Division.
19
Confidential
2017 Revenue Bridge(1)
(1) Based on guidance issued 4/26/17 ($, MMs)
We estimate revenue of $255 – $265 million in 2017…
20
• NEO estimates that growth in the clinical business will be impacted by approximately $4 MM of
distractions related to the Clarient Integration activities and approximately $1.8 MM of cuts to
flow cytometry reimbursement in 2017.
$244.1
$260.0$17.7 $4.0 ($1.8) ($4.0)
$160
$180
$200
$220
$240
$260
$280
2016 Clinical Growth Pharma Growth Flow Cuts Integ. Distractions 2017
Confidential 21
2017 Adjusted EBITDA Bridge (1)
• NEO expects to realize $20-30 MM of total synergies in the first 3 years after the Clarient acquisition with approximately
75% of such synergies being cost synergies as a result of efficiencies gained through the combination with Clarient.
• 2017 Adjusted EBITDA assumes $8 mm of cost synergies are realized, which are partially offset by the impact of the
integrations distractions and flow cytometry reimbursement reductions (each at 90% of the revenue impact).
(1) Based on guidance issued 4/26/17 ($, MMs)
We estimate Adj. EBITDA of $39 – $46 million in 2017
21
$34.7
$42.5
$5.0
$8.0 ($1.6) ($3.6)
$0
$10
$20
$30
$40
$50
$60
2016 Growth Synergies Flow Cuts All Other 2017
22
2020 Goals
By providing uncompromising quality, exceptional service &
innovative solutions, we will be the world’s leading cancer
testing and information company!
15%+
Clinical
Volume
CAGR
20%+
Pharma
Services
Revenue
CAGR
20-25%
Adjusted
EBITDA
Margins
Appendix
23
24
NeoGenomics – At a Glance
• # 1 or 2 largest somatic cancer testing Lab in America
• Most advanced and comprehensive cancer testing menu in U.S.
• Approximately 650,000 tests will be performed in 2017
• 160,000 s.f. of space, 1,000+ employees, and > 50 M.D.s & PhDs
• Outstanding franchise with Hospitals/Pathologists
• Leader in Immuno-Oncology testing with Pharma & clinical clients
CMS Reimbursement is Stable in 2017
CPT Proc
Code Procedure Description
National
Unadj Rate
2014
National
Unadj
Rate
2015
National
Unadj
Rate
2016
2016 vs
2015 %
change
Final Rule -
Implied
National
Unadj Rate
2017 (1)
% Change
2017 Final
Rule vs
Prelim Rule
% Change
2017 Final
Rule vs
2016
88184 FLOW 1ST MARKER 87.77$ 94.51$ 76.26$ -19.3% 61.73$ 0.3% -19.1%
88185 FLOW EACH ADDL MARKER 53.73$ 57.49$ 46.55$ -19.0% 37.68$ 0.3% -19.1%
88189 FLOW INTERP 16 OR MORE MARKERS 110.69$ 113.91$ 114.22$ 0.3% 92.59$ 0.3% -18.9%
88374 FISH AUTOMATED PER PROBE (Multiplex Probe Stain) 255.77$ 205.54$ 345.87$ 68.3% 343.45$ 1.3% -0.7%
88374-TC FISH AUTOMATED PER PROBE TECH (Multiplex Probe Stai 193.08$ 160.26$ 299.68$ 87.0% 297.16$ 1.4% -0.8%
88374-26 FISH AUTOMATED PER PROBE INTERP (Multiplex Probe St 62.69$ 45.28$ 46.19$ 2.0% 46.30$ 0.3% 0.2%
88121 FISH AUTOMATED - UROVYSION 508.30$ 556.97$ 558.55$ 0.3% 553.76$ 1.3% -0.9%
88121-TC FISH AUTOMATED - UROVYSION 459.99$ 505.23$ 506.63$ 0.3% 501.72$ 1.4% -1.0%
88121-26 FISH AUTOMATED - UROVYSION 48.31$ 51.74$ 51.92$ 0.3% 52.04$ 0.3% 0.2%
Uses G0461 in 2014
88342 IMMUNOHISTOCHEMISTRY (1st Stain) 88.48$ 90.91$ 107.41$ 18.1% 108.38$ 0.7% 0.9%
88342 - TC IMMUNOHISTOCHEMISTRY TECH (1st Stain) 57.67$ 54.26$ 70.18$ 29.3% 71.06$ 0.8% 1.3%
88342 - PC IMMUNOHISTOCHEMISTRY INTERP (1st Stain) 30.81$ 36.65$ 37.24$ 1.6% 37.32$ 0.3% 0.2%
Uses G0462 in 2014
88341 IMMUNOHISTOCHEMISTRY (Add'l Stain) 68.42$ 67.91$ 90.23$ 32.9% 92.23$ 2.3% 2.2%
88341 - TC IMMUNOHISTOCHEMISTRY TECH (Add'l Stain) 55.88$ 45.99$ 62.30$ 35.5% 62.45$ 0.9% 0.2%
88341 - PC IMMUNOHISTOCHEMISTRY INTERP (Add'l Stain) 12.54$ 21.92$ 27.93$ 27.4% 29.79$ 5.4% 6.7%
Uses G0461 in 2014
88344 IMMUNOHISTOCHEMISTRY (each Multiplex Stain) 88.48$ 117.50$ 174.01$ 48.1% 174.78$ 0.9% 0.4%
88344 - TC IMMUNOHISTOCHEMISTRY TECH (each Multiplex Stain) 57.67$ 77.26$ 133.19$ 72.4% 133.86$ 1.1% 0.5%
88344 - PC IMMUNOHISTOCHEMISTRY INTERP (each Multiplex Stain) 30.81$ 40.25$ 40.82$ 1.4% 40.91$ 0.3% 0.2%
88361 MORPHOLOGY, EACH ANTIBODY - AUTOMATED 157.98$ 170.32$ 149.66$ -12.1% 156.83$ 0.5% 4.8%
88361-TC MORPHOLOGY TECH, EACH ANTIBODY - AUTOMATED 98.51$ 109.96$ 88.79$ -19.3% 95.82$ 1.1% 7.9%
88361-26 MORPHOLOGY INTERP, EA ANTIBODY - AUTOMATED 59.47$ 60.37$ 60.87$ 0.8% 61.01$ -0.3% 0.2%
(1) Source: CMS Final Rule on 2017 Physician Fee Schedule (CMS-1654-F issued 11/2/16). Assumes no other Physician Fee Schedule rule changes or limited coverage determinations
are implemented for 2017. Uses Estimated Conversion Factor of 35.8887 taken from Section VI(C)(1) of CMS-1654-F (page 1326 of display copy of rule on CMS website).
25
Confidential
Impact of Clarient Acquisition
26
Key Benefits
Outstanding Customer Mix
Similar Product Lines (1)
Synergy potential of $20mm-$30mm within 3 years
East Coast/West Coast Labs w/similar instrumentation
Combine Irvine Lab into 78,000 sq. ft. Aliso Viejo Lab
Strategic leadership in Heme cancers and Solid tumors
Significant Pharma Services opportunities
IHC
42%
FISH/ISH
19%
FLOW
14%
Molecular
15%
Cyto
5%
Other
5%
(1) Clinical operations only. Percentage of tests Performed.
SIMILAR CLINICAL
CUSTOMERS
(About 2,400)
New BIOPHARMA
CUSTOMERS
(200 Projects with
>30 Customers)
26
The Deal – Closed on 12/30/15
Approx. $292 million purchase price --- $80mm cash, 15mm
shares of NEO, $110mm Pfd. Stock
Clarient 2015 revenue $125mm and $9mm Adj EBITDA
$55 mm of Pfd Stock Redeemed at 9.1% discount in Dec 16
Bank debt refinanced in Dec 16 at favorable rates (L+350)
GE currently holds 15mm NEO shares plus $45mm Pfd Stock
2017 Guidance*
• Revenue: $255 - 265 MM
• Adjusted EBITDA* 39 - 46 MM
• Adjusted Net Income* 15 - 18 MM
• Adjusted Diluted EPS* $0.17 - 0.21
* See Appendix for definitions of Adjusted EBITDA, Adjusted Net Income and Adjusted Diluted EPS as well as a reconciliation of GAAP
Net Income to Adj. EBITDA, Adj. Net Income and Adj. Diluted EPS. NeoGenomics believes that Adjusted EBITDA, Adjusted Net Income
and Adjusted Diluted EPS provide a more consistent measurement of operating performance and trends across reporting periods by
excluding from income those cash and non-cash items of expense (income) not directly related to ongoing operations. Adjusted figures
also assists investors in performing analysis that is consistent with financial models developed by research analysts. Investors should
consider non-GAAP results together with GAAP results in analyzing NeoGenomics financial performance.
2017 net income available to common stockholders calculated in accordance with GAAP will be impacted by certain non-cash charges,
including: (i) expenses related to variable stock-based compensation, (ii) approximately $7.3 million of expense related to the
amortization of customers lists and other intangibles from the Clarient acquisition, (iii) approximately $3.8 million of deemed preferred
stock dividends, and (iv) approximately $6.7 million of the amortization of the beneficial conversion feature related to the preferred stock
issued in connection with the Clarient acquisition. These non-cash charges have been included in GAAP net income (loss) available to
common shareholders and GAAP net income (loss) per share; however, they have been removed from Adjusted Net Income and Adjusted
Diluted Net Income per Share. As a result, the Company expects 2017 diluted net loss per share calculated in accordance with GAAP to
be $0.26 - $0.28 per share lower than 2017 Adjusted Diluted Net Income per Share.
27
Confidential
Reconciliation of GAAP Net Income to Adjusted EBITDA
Use of non-GAAP Financial Measures: NeoGenomics believes that using non-GAAP financial measures provides useful
supplemental information to investors and facilitates the analysis of the company’s core operating results and the comparison of
core operating results more consistently across reporting periods. Management also uses non-GAAP financial measures for financial
and operational decision making, planning and forecasting purposes and to manage the company’s business. These non-GAAP
financial measures enable investors to evaluate our operating results and future prospects in the same manner as management and
research analysts. The non-GAAP financial measures do not replace the presentation of GAAP financial results and should only be
used as a supplement to and not as a substitute for financial results presented in accordance with GAAP. There are limitations
inherent in non-GAAP financial measures because they exclude charges and credits that are required to be included in a GAAP
presentation, and do not therefore present the full measure of NeoGenomics recorded costs against its net revenue. In addition,
non-GAAP financial measures as defined by NeoGenomics may differ from non-GAAP measures used by other companies.
28
Reconciliation of GAAP Net Income to Non-GAAP EBITDA and Adjusted EBITDA
(Unaudited, in thousands)
For the Three-Months
Ended March 31,
2017 2016
Net Income (Loss) (per GAAP) $ (654) $ 155
Adjustments to Net Income (Loss):
Interest expense 1,364 1,593
Amortization of intangibles 1,725 2,026
Income tax expense (benefit) (825) 174
Depreciation 3,979 3,585
EBITDA $ 5,589 $ 7,533
Further adjustments to EBITDA:
Non-cash stock based compensation 1,130 703
Facility moving expenses 351 -
Adjusted EBITDA (non-GAAP) $ 7,070 $ 8,236
Confidential
Reconciliation of GAAP Net Income to Adjusted Net
Income & GAAP Diluted EPS to Adjusted Diluted EPS
29
Reconciliation of GAAP Net Income Available to Common Stockholders to Non-GAAP Adjusted Net
Income and GAAP Earnings per Share to Non-GAAP Adjusted Earnings per Share
(Unaudited, in thousands)
For the Three-Months
Ended March 31,
2017 2016
Net loss available to common shareholders (GAAP) $ (3,220) $ (5,412)
Adjustments to Net Loss:
Amortization of intangibles 1,725 2,026
Non-cash stock-based compensation expenses 1,130 703
Deemed dividends/ PIK dividends on preferred stock 894 1,840
Facility moving expenses 351 -
Amortization of preferred stock beneficial conversion feature 1,672 3,727
Adjusted net income (non-GAAP) $ 2,552 $ 2,884
Net loss per common share (GAAP)
Diluted EPS $ (0.04) $ (0.07)
Adjustments to diluted loss per share:
Amortization of intangibles 0.02 0.02
Non-cash stock-based compensation expenses 0.01 0.01
Deemed dividends/ PIK dividends on preferred stock 0.01 0.02
Facility moving expenses - -
Amortization of preferred stock beneficial conversion feature 0.02 0.04
Impact of including preferred shares and stock options/warrants in Adj.
Diluted Shares (3)
0.01 0.01
Adjusted Diluted EPS (non-GAAP) 0.03 0.03
Confidential
“Adjusted EBITDA” is defined by NeoGenomics as net income from continuing operations before: (i) interest expense, (ii) tax expense,
(iii) depreciation and amortization expense, (iv) non-cash, stock-based compensation expense, and if applicable in a reporting period
(v) acquisition related transaction expenses and other significant non-recurring or non-operating (income) or expenses.
“Adjusted Net Income” is defined by NeoGenomics as net income available to common shareholders from continuing operations plus:
(i) non-cash amortization of customer lists and other intangible assets, (ii) non-cash, stock-based compensation expense, (iii) non-cash
deemed dividends on preferred stock, (iv) non-cash amortization of preferred stock beneficial conversion feature, and if applicable in a
reporting period (v) acquisition related transaction expenses and other significant non-recurring or non-operating (income) or
expenses.
“Adjusted Diluted EPS” is defined by NeoGenomics as Adjusted Net Income divided by Adjusted Diluted Shares outstanding. Adjusted
Diluted Shares outstanding is the sum of Diluted shares outstanding and the weighted average number of common shares that would
be outstanding if the preferred stock were converted into common stock on the original issue date based on the number of days such
common shares would have been outstanding in the reporting period. In addition, If GAAP Net Income is negative and Adjusted Net
Income is positive, Adjusted Diluted Shares will also include any options or warrants that would be outstanding as dilutive instruments
using the treasury stock method.
Reconciliation of GAAP Net Income to Adjusted Figures
30
Weighted average shares used in computation of adjusted diluted
earnings per share:
Diluted Common Shares (GAAP) 78,650 76,068
Options & warrants not included in GAAP Diluted Shares (using
treasury stock method) 1,693 2,271
Weighted Avg. Preferred Shares (as converted) 6,600 14,667
Adjusted Diluted Shares outstanding (non-GAAP) 86,943 93,006
For the Three-Months
Ended March 31,
2017 2016

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March 2017 Company Overview Presentation by NeoGenomics, (Nasdaq: NEO) a fast growing cancer genetic testing lab traded on Nasdaq.

  • 2. 2 Forward-looking Statements This presentation contains statements which constitute forward-looking statements within the meaning of Section 27A of the Securities Act, as amended; Section 21E of the Securities Exchange Act of 1934; and the Private Securities Litigation Reform Act of 1995. The words “may”, “would”, “could”, “will”, “expect”, “estimate”, “anticipate”, “believe”, “intend”, “plan”, “goal”, and similar expressions and variations thereof are intended to specifically identify forward-looking statements. All statements that are not statements of historical fact are forward-looking statements. Investors and prospective investors are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those projected in the forward-looking statements as a result of various factors. The risks that might cause such differences are identified in our filings with the Securities and Exchange Commission. We undertake no obligation to publicly update or revise the forward looking statements made in this presentation to reflect events or circumstances after the date of this presentation or to reflect the occurrence of unanticipated events.
  • 3. 3 Investment Highlights Leading pure-play oncology testing company Unique client partnership business model History of strong clinical growth & rapid innovation Favorable demographics driving expanding market Increasing momentum in Pharma Services Realization of Clarient cost synergies accelerating Significant opportunities for market share gains and Adjusted EBITDA expansion
  • 4. 4 Financial Facts NASDAQ Ticker: NEO Stock Price (6/5/17): $7.78 Basic Shares Outstanding: 79.2 MM Avg. Daily Volume (3 Mos.): 372K 52 Week Low/High: $6.90/9.88 % Held by Insiders: 17.5% Market Cap (6/5/17) $616.5 MM Debt (MRQ) 111.0 Preferred Stock (Redemption Value) 46.6 Less Cash (MRQ) (11.0) Enterprise Value $763.1 MM EV/ 2017 Consensus Rev 2.9x Recent Financial Performance ($,MMs) Recent Financial Performance FY 2016 YoY % Chg. * Clinical Testing Rev $222.0 124% Pharma Service Rev 22.1 1,728% Total Revenue 244.1 145% Adjusted EBITDA $34.7 259% % EBITDA Margin 14.2% +450bps * % Change includes the effects of Clarient Acquisition. Stock Information Market Capitalization & Enterprise Value 2016 Financial Highlights5 Year Stock Price Performance
  • 5. 5 Proven Management Team • Combination of industry-experienced medical, financial and technical professionals • Integral role in the Company’s industry leading operating model and unrivaled growth trajectory • Instrumental to the successful integration of the Clarient Acquisition Position NEO Experience Industry Experience Douglas VanOort Chief Executive Officer 8 years 35 years Maher Albitar, M.D. SVP & Chief Medical Officer 5 years 26 years Robert Shovlin President of Clinical Services Division 3 years 20 years Steven Jones Executive Vice President 15 years 15 years George Cardoza SVP & Chief Financial Officer 8 years 23 years Jennifer Balliet Chief Culture Officer 9 years 9 years Steven Ross Chief Information Officer 3 years 3 years Denise Pedulla General Counsel 2 years 21 years Bill Bonello Vice President, Treasurer & Dir. of Corp. Dev. <1 year 10 years Steven Brodie, Ph.D., FACMG Vice President of Operations 8 years 14 years Fred Weidig Vice President, Finance & Principal Accounting Officer 10 years 10 years
  • 6. NEO’s Proven Track Record of Consistent Growth Clinical Genetic Testing Annual Revenue Clinical Genetic Tests Performed ($, 000s) * Base NEO represents organic revenue and test volume growth from legacy business and excludes the impacts from the PathLogic and Clarient acquisitions. 6 $558 $1,885 $6,476 $11,505 $20,015 $29,469 $34,371 $43,484 $59,866 $66,467 $82,194 $188,374 $214,708 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Pro Forma Clarient 2015 Genetic Test Revenue NEO Clinical Genetic Testing Revenue 1,152 4,082 12,838 20,998 32,539 45,675 57,332 76,288 114,606 137,317 177,279 490,450 563,132 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Pro Forma Clarient 2015 Clinical Genetic Tests NEO Clincial Genetic Tests Performed
  • 7. 7 Growth Goals • Mid-teens organic clinical volume growth • 20%+ organic Pharma revenue growth • 25-35% incremental Adj. EBITDA on revenue growth Driven by: − Comprehensive test menu – “One-Stop Shop” − Innovation in test development − Demographics and medical advances − Increased efficiencies
  • 8. Strong Track Record of Innovation Leader in FISH, Flow Cytometry, IHC, Molecular, Immuno-Oncology (PD-L1) and Emerging Leader in Liquid Biopsy Testing! 70 new/revised tests, incl: NeoLABTM Liquid Biopsies • MDS/CMML Profile • AML Profile • FLT3 Mutation Analysis • NPM1 Mutation Analysis • PML-RARA Translocation • RUNX1-RNX1T1Transloc • INV16 Translocation • c-kit Mutation Analysis • IDH1 Mutation Analysis • IDH2 Mutation Analysis • NRAS Mutation Analysis • KRAS Mutation Analysis • BTK Inhibitor Resistance • Solid Tumor Monitoring Germline MolDx Testing • BRCA1 & BRCA2 • Lynch Syndrome (colon) • 73 Gene Comprehensive Predisposition Panel Other • ALK, ROS1, RET Fusion • Sarcoma gene Fusion • NeoSITE Cervical FISH • Expanded IHC Menu • Smart Flow Cytometry • 10-color Flow Cytometry • Implemented Adv MolDx platform in lieu of Kits • 28 new Molecular Assays • Proprietary method for increasing sensitivity of Sanger sequencing • 7 NeoTYPE MolDx Panels • SVM for FISH (Patent App) • Barrett’s Esoph. FISH (Patent App) • NeoARRAY/SNP Cytogenetics • Internalized send-outs 40 new Molecular tests, incl: • Add’l NeoTYPE Panels • Next Generation Sequencing (48 genes) • ROS1 FISH • NeoSITE Melanoma FISH • Plasma/Urine-based Prostate Test (Patent App) • SVM-based Cytogenetics Analysis System • SVM-based Automated FISH Analysis System v2 • Began development of NeoLAB (Liquid Alternative to Biopsy) Prostate Cx test 60 new/revised tests, incl: • 24 new NeoTYPE Next Generation Sequencing Profiles • 26 new IHC/ISH tests • Additional NeoLAB Prostate clinical studies • AML Extended FISH Panel • AML Favorable-Risk FISH Panel • MDS Extended FISH Panel • Plasma Cell Myeloma Risk Stratification FISH Panel • RET FISH • MET FISH • ALL Adult & Pediatric FISH Panels • HER2 Breast Equivocal FISH Panel • BRAF Translocation FISH • Chromosome 1 POC Ploidy • Launched robotic FISH-Cyto processing platform 50 new/revised tests, incl: • Comprehensive PD-L1 Testing (three FDA-cleared and one LDT) • 1,385 genes RNA-Based Pan Cancer NGS Fusion, Mutation and Expression Profiling. • Smart Flow Cytometry data analysis platform • Pediatric Hereditary Susceptibility • Hereditary DNA Panel (prostate) • Inherited Bone Marrow Failure • MET Exon 14 Deletion Analysis • NRAS Exon 4 Mutation Analysis • NGS ALK, NTRK, RET, ROS1 Fusion NeoLABTM Liquid Biopsies • NeoLAB Myeloid Disorders Profile • EGFR T790M NeoTYPETM Multi Modality Profiles • AITL/Peripheral T-Cell Lymphoma • Thyroid Profile • Brain Tumor Profile • Melanoma Profile • Liposarcoma Fusion Profile • Head & Neck Tumor Profile FISH & IHC • FISH Testing for EWSR1, SS18, DDIT3, STAT 6, BCL2, & TCL1 • IHC Testing for CXCL13, BAP1, INI1, MUC4 • PD-LI 2012 2013 2014 2015 2016 8
  • 9. Positive Demographic Tailwinds and …. Shifting Demographics Incidence of Cancer by Age 0.0 20.0 40.0 60.0 80.0 100.0 120.0 Age 60-64 Age 65-74 Age 75-84 Age 85+ 1.0% 2.7% 5.1% 13.8% 24.4% 26.2% 18.8% 7.9% < 20 20-34 35-44 45-54 55-64 65-74 74-84 > 84 Source: United States Census Bureau Source: National Cancer Institute 9
  • 10. Rapidly Growing Market Opportunity Source: National Institutes of Health (NIH) 10 • Aging Population – incidence increases with age • Increased Prevalence – better treatments lead to more survivors and monitoring • Scientific advances – driving targeted therapeutics • Increased cost of drugs – more careful triage and monitoring
  • 11. Positions NEO for Additional Market Share Gains 11 • Based on CMS Data, the Cancer Market was $5.1B in 2014 • Assuming modest growth, the Cancer Market is about $6B in 2017 • NeoGenomics 2017 Revenue estimate of $260M --- about 5% of the market • Industry is highly fragmented – and is expected to consolidate further over time
  • 12. Opportunities by Customer Type Pathologists & Hospitals (about 80% of Revenue) • Large Market with 5,600 Hospitals in U.S., and 18,000 active Pathologists • Enable Pathologists to practice using sophisticated tools/tests and “tech-only” services • Unique ability to be “One-stop shop” with comprehensive oncology test menu • Competitive pricing under contract, and agreements with hospitals & hospital GPOs Oncologists, Hematologists & Clinicians (about 10% of Revenue) • Disease Panels, liquid biopsies, and comprehensive molecular menus • Increasing opportunity to service larger practices with Partnership-based tech-only model • Contracts with key Managed Care organizations Pharma Services & Other (about 10% of Revenue) • Contract research/clinical trial support work for Pharma clients • Opening in Geneva, Switzerland to handle European and Global studies • MultiOmyx platform is a unique offering gaining acceptance by Pharma firms 12
  • 13. Evolution of Payer Mix For Clinical Testing Medicare reimbursements have fallen from 52% of payer mix in 2010 to 16% in 2016! (1) 2016 is a blended average estimate of the Base NEO and Clarient payer mixes. 13 52% 44% 37% 27% 21% 21% 16% 23% 26% 34% 45% 51% 59% 58% 23% 29% 28% 28% 29% 20% 26% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% 2010 2011 2012 2013 2014 2015 2016 Medicare (Incl. Medicaid) Client Bill (Hospitals) Commercial Insurance Other/Accruals/Pt. Pay (1)
  • 14. Accelerating Improvements in Cost per Test 14
  • 15. 15 Historically Steady Margins Despite Lower Avg. Unit Prices* * To facilitate comparison, all data is for Clinical Genetic Testing and excludes the impact from the PathLogic acquisition and Pharma Services. (1) Productivity calculated as the average number of lab tests completed per month per laboratory FTE. 45.9% 44.7% 44.8% 47.7% 48.0% 46.1% 47.2% -40.9% 65.6% -50% -40% -30% -20% -10% 0% 10% 20% 30% 40% 50% 60% 70% 35% 40% 45% 50% 55% 2010 2011 2012 2013 2014 2015 2016 Gross Margin % From Clinical Genetic Testing Cum Change in Avg Rev/ Clinical Genetic Test Since 2009 Cum Change in Productivity Since 2009 CumChangeinAvgRev/Test&Productivity (1)
  • 16. Clarient Cost Synergies and Opportunities 16 2015 Adjusted EBITDA NeoGenomics $ 9.7 MM Clarient Pro Forma $ 9.2 MM Pro Forma Combined $18.9 MM 2016 “New Neo” EBITDA $ 34.7 MM Clearly, “synergies” showed up in 2016 --- and there are more to be realized in 2017- 18 2017 – 2018 Opportunities: • Laboratory facilities consolidated on 3/26/17 – teams now working as one • Ability to run combined batches in So. California rather than two batches • Ongoing supplier re-negotiations as contracts end – we have 2x volume • Irvine laboratory closed on 4/30 – saving over $50k per month • Cross selling now possible – accounts all on one laboratory information system • Pharma services just starting to access Neo’s leading Molecular menu “9 + 9 equals 34”
  • 17. Growing Pharma Services $41.6mm Backlog as of 3/31/17 - Approx. 400 active projects from 100+ Clients • 50% of projects in pre-clinical space – often leading to more lucrative Phase I, II, and III work • Major PD-L1 testing site for Keytruda (Merck) and Opdivo (BMS) – Leader in Immuno-Oncology • Medical and Scientific expertise, comprehensive test menu, & extensive clinical network • International presence in 2017 with Geneva, Switzerland Lab 17
  • 18. 18 Pharma Services Revenue & Backlog $5.1 $6.8 $5.0 $5.2 $5.0 $23.7 $26.0 $33.0 $36.8 $41.6 $0 $10 $20 $30 $40 $50 Q1'16 Q2'16 Q3'16 Q4'16 Q1'17 Revenue Backlog ($, MMs)
  • 19. Recent Financial Information (P&L) ($, 000's) 2014(1) 2015(2)(3) 2016(3) Q1 2016 Q1 2017(4) Total Revenue $ 87,069 $ 99,802 $ 244,083 $ 59,704 $ 61,676 % Growth (YoY) 31.0% 14.6% 144.6% 159.3% 3.3% Total Gross Profit 40,714 43,756 110,379 27,173 27,196 Gross Margin % 46.8% 43.8% 45.2% 45.5% 44.1% Total SG&A (Incl R&D) Exp(3) 38,496 49,391 107,804 25,251 27,311 SG&A as a % of Rev 44.2% 49.5% 44.2% 42.3% 44.3% Adjusted Net Income/(Loss)* 2,689 4,042 14,399 $ 2,884 $ 2,552 Adjusted Diluted EPS* $0.05 $0.06 $0.15 $0.03 $0.03 Adjusted EBITDA* $ 9,176 $ 9,672 $ 34,685 $ 8,236 $ 7,070 % Growth 7.8% 9.7% 258.4% 442.2% -14.2% Operating Data(5) % Growth in Clinical Genetic Tests (YoY) 29.1% 25.6% 154.6% 174.7% 15.3% Avg. Revenue/Clinical Genetic Test $ 464 $ 412 $ 381 $ 391 $ 354 % Change (YoY) -4.2% -11.2% -6.8% -6.1% -9.4% Avg. COGS/Clinical Genetic Test $ 241 $ 220 $ 201 $ 206 $ 186 % Change (YoY) -4.7% -8.6% -8.7% -12.7% -9.7% * See Appendix for definitions of Adj. EBITDA, Adj. Net Income and Adj. Diluted EPS as well as a reconciliation of GAAP Net Income to Adjusted financial information. (1) 2014 figures include the results of PathLogic from the date of the acquisition on July 8, 2014. (2) 2015 figures include the results of Clarient for two days from the date of the acquisition on December 30, 2015 and $4.7 MM of Clarient transaction expenses in SG&A. (3) 2016 SG&A includes 7.4 MM of one-time bank debt retirement fees and impairment charges. (4) Q1 2017 SG&A includes $0.4 MM of one-time expenses associated with the move of NeoGenomics Irvine, CA facility into its Aliso Viejo, CA facility. (5) All Operating data refers to Clinical Genetic Testing and excludes the results from PathLogic and the Pharma Services Division. 19
  • 20. Confidential 2017 Revenue Bridge(1) (1) Based on guidance issued 4/26/17 ($, MMs) We estimate revenue of $255 – $265 million in 2017… 20 • NEO estimates that growth in the clinical business will be impacted by approximately $4 MM of distractions related to the Clarient Integration activities and approximately $1.8 MM of cuts to flow cytometry reimbursement in 2017. $244.1 $260.0$17.7 $4.0 ($1.8) ($4.0) $160 $180 $200 $220 $240 $260 $280 2016 Clinical Growth Pharma Growth Flow Cuts Integ. Distractions 2017
  • 21. Confidential 21 2017 Adjusted EBITDA Bridge (1) • NEO expects to realize $20-30 MM of total synergies in the first 3 years after the Clarient acquisition with approximately 75% of such synergies being cost synergies as a result of efficiencies gained through the combination with Clarient. • 2017 Adjusted EBITDA assumes $8 mm of cost synergies are realized, which are partially offset by the impact of the integrations distractions and flow cytometry reimbursement reductions (each at 90% of the revenue impact). (1) Based on guidance issued 4/26/17 ($, MMs) We estimate Adj. EBITDA of $39 – $46 million in 2017 21 $34.7 $42.5 $5.0 $8.0 ($1.6) ($3.6) $0 $10 $20 $30 $40 $50 $60 2016 Growth Synergies Flow Cuts All Other 2017
  • 22. 22 2020 Goals By providing uncompromising quality, exceptional service & innovative solutions, we will be the world’s leading cancer testing and information company! 15%+ Clinical Volume CAGR 20%+ Pharma Services Revenue CAGR 20-25% Adjusted EBITDA Margins
  • 24. 24 NeoGenomics – At a Glance • # 1 or 2 largest somatic cancer testing Lab in America • Most advanced and comprehensive cancer testing menu in U.S. • Approximately 650,000 tests will be performed in 2017 • 160,000 s.f. of space, 1,000+ employees, and > 50 M.D.s & PhDs • Outstanding franchise with Hospitals/Pathologists • Leader in Immuno-Oncology testing with Pharma & clinical clients
  • 25. CMS Reimbursement is Stable in 2017 CPT Proc Code Procedure Description National Unadj Rate 2014 National Unadj Rate 2015 National Unadj Rate 2016 2016 vs 2015 % change Final Rule - Implied National Unadj Rate 2017 (1) % Change 2017 Final Rule vs Prelim Rule % Change 2017 Final Rule vs 2016 88184 FLOW 1ST MARKER 87.77$ 94.51$ 76.26$ -19.3% 61.73$ 0.3% -19.1% 88185 FLOW EACH ADDL MARKER 53.73$ 57.49$ 46.55$ -19.0% 37.68$ 0.3% -19.1% 88189 FLOW INTERP 16 OR MORE MARKERS 110.69$ 113.91$ 114.22$ 0.3% 92.59$ 0.3% -18.9% 88374 FISH AUTOMATED PER PROBE (Multiplex Probe Stain) 255.77$ 205.54$ 345.87$ 68.3% 343.45$ 1.3% -0.7% 88374-TC FISH AUTOMATED PER PROBE TECH (Multiplex Probe Stai 193.08$ 160.26$ 299.68$ 87.0% 297.16$ 1.4% -0.8% 88374-26 FISH AUTOMATED PER PROBE INTERP (Multiplex Probe St 62.69$ 45.28$ 46.19$ 2.0% 46.30$ 0.3% 0.2% 88121 FISH AUTOMATED - UROVYSION 508.30$ 556.97$ 558.55$ 0.3% 553.76$ 1.3% -0.9% 88121-TC FISH AUTOMATED - UROVYSION 459.99$ 505.23$ 506.63$ 0.3% 501.72$ 1.4% -1.0% 88121-26 FISH AUTOMATED - UROVYSION 48.31$ 51.74$ 51.92$ 0.3% 52.04$ 0.3% 0.2% Uses G0461 in 2014 88342 IMMUNOHISTOCHEMISTRY (1st Stain) 88.48$ 90.91$ 107.41$ 18.1% 108.38$ 0.7% 0.9% 88342 - TC IMMUNOHISTOCHEMISTRY TECH (1st Stain) 57.67$ 54.26$ 70.18$ 29.3% 71.06$ 0.8% 1.3% 88342 - PC IMMUNOHISTOCHEMISTRY INTERP (1st Stain) 30.81$ 36.65$ 37.24$ 1.6% 37.32$ 0.3% 0.2% Uses G0462 in 2014 88341 IMMUNOHISTOCHEMISTRY (Add'l Stain) 68.42$ 67.91$ 90.23$ 32.9% 92.23$ 2.3% 2.2% 88341 - TC IMMUNOHISTOCHEMISTRY TECH (Add'l Stain) 55.88$ 45.99$ 62.30$ 35.5% 62.45$ 0.9% 0.2% 88341 - PC IMMUNOHISTOCHEMISTRY INTERP (Add'l Stain) 12.54$ 21.92$ 27.93$ 27.4% 29.79$ 5.4% 6.7% Uses G0461 in 2014 88344 IMMUNOHISTOCHEMISTRY (each Multiplex Stain) 88.48$ 117.50$ 174.01$ 48.1% 174.78$ 0.9% 0.4% 88344 - TC IMMUNOHISTOCHEMISTRY TECH (each Multiplex Stain) 57.67$ 77.26$ 133.19$ 72.4% 133.86$ 1.1% 0.5% 88344 - PC IMMUNOHISTOCHEMISTRY INTERP (each Multiplex Stain) 30.81$ 40.25$ 40.82$ 1.4% 40.91$ 0.3% 0.2% 88361 MORPHOLOGY, EACH ANTIBODY - AUTOMATED 157.98$ 170.32$ 149.66$ -12.1% 156.83$ 0.5% 4.8% 88361-TC MORPHOLOGY TECH, EACH ANTIBODY - AUTOMATED 98.51$ 109.96$ 88.79$ -19.3% 95.82$ 1.1% 7.9% 88361-26 MORPHOLOGY INTERP, EA ANTIBODY - AUTOMATED 59.47$ 60.37$ 60.87$ 0.8% 61.01$ -0.3% 0.2% (1) Source: CMS Final Rule on 2017 Physician Fee Schedule (CMS-1654-F issued 11/2/16). Assumes no other Physician Fee Schedule rule changes or limited coverage determinations are implemented for 2017. Uses Estimated Conversion Factor of 35.8887 taken from Section VI(C)(1) of CMS-1654-F (page 1326 of display copy of rule on CMS website). 25
  • 26. Confidential Impact of Clarient Acquisition 26 Key Benefits Outstanding Customer Mix Similar Product Lines (1) Synergy potential of $20mm-$30mm within 3 years East Coast/West Coast Labs w/similar instrumentation Combine Irvine Lab into 78,000 sq. ft. Aliso Viejo Lab Strategic leadership in Heme cancers and Solid tumors Significant Pharma Services opportunities IHC 42% FISH/ISH 19% FLOW 14% Molecular 15% Cyto 5% Other 5% (1) Clinical operations only. Percentage of tests Performed. SIMILAR CLINICAL CUSTOMERS (About 2,400) New BIOPHARMA CUSTOMERS (200 Projects with >30 Customers) 26 The Deal – Closed on 12/30/15 Approx. $292 million purchase price --- $80mm cash, 15mm shares of NEO, $110mm Pfd. Stock Clarient 2015 revenue $125mm and $9mm Adj EBITDA $55 mm of Pfd Stock Redeemed at 9.1% discount in Dec 16 Bank debt refinanced in Dec 16 at favorable rates (L+350) GE currently holds 15mm NEO shares plus $45mm Pfd Stock
  • 27. 2017 Guidance* • Revenue: $255 - 265 MM • Adjusted EBITDA* 39 - 46 MM • Adjusted Net Income* 15 - 18 MM • Adjusted Diluted EPS* $0.17 - 0.21 * See Appendix for definitions of Adjusted EBITDA, Adjusted Net Income and Adjusted Diluted EPS as well as a reconciliation of GAAP Net Income to Adj. EBITDA, Adj. Net Income and Adj. Diluted EPS. NeoGenomics believes that Adjusted EBITDA, Adjusted Net Income and Adjusted Diluted EPS provide a more consistent measurement of operating performance and trends across reporting periods by excluding from income those cash and non-cash items of expense (income) not directly related to ongoing operations. Adjusted figures also assists investors in performing analysis that is consistent with financial models developed by research analysts. Investors should consider non-GAAP results together with GAAP results in analyzing NeoGenomics financial performance. 2017 net income available to common stockholders calculated in accordance with GAAP will be impacted by certain non-cash charges, including: (i) expenses related to variable stock-based compensation, (ii) approximately $7.3 million of expense related to the amortization of customers lists and other intangibles from the Clarient acquisition, (iii) approximately $3.8 million of deemed preferred stock dividends, and (iv) approximately $6.7 million of the amortization of the beneficial conversion feature related to the preferred stock issued in connection with the Clarient acquisition. These non-cash charges have been included in GAAP net income (loss) available to common shareholders and GAAP net income (loss) per share; however, they have been removed from Adjusted Net Income and Adjusted Diluted Net Income per Share. As a result, the Company expects 2017 diluted net loss per share calculated in accordance with GAAP to be $0.26 - $0.28 per share lower than 2017 Adjusted Diluted Net Income per Share. 27
  • 28. Confidential Reconciliation of GAAP Net Income to Adjusted EBITDA Use of non-GAAP Financial Measures: NeoGenomics believes that using non-GAAP financial measures provides useful supplemental information to investors and facilitates the analysis of the company’s core operating results and the comparison of core operating results more consistently across reporting periods. Management also uses non-GAAP financial measures for financial and operational decision making, planning and forecasting purposes and to manage the company’s business. These non-GAAP financial measures enable investors to evaluate our operating results and future prospects in the same manner as management and research analysts. The non-GAAP financial measures do not replace the presentation of GAAP financial results and should only be used as a supplement to and not as a substitute for financial results presented in accordance with GAAP. There are limitations inherent in non-GAAP financial measures because they exclude charges and credits that are required to be included in a GAAP presentation, and do not therefore present the full measure of NeoGenomics recorded costs against its net revenue. In addition, non-GAAP financial measures as defined by NeoGenomics may differ from non-GAAP measures used by other companies. 28 Reconciliation of GAAP Net Income to Non-GAAP EBITDA and Adjusted EBITDA (Unaudited, in thousands) For the Three-Months Ended March 31, 2017 2016 Net Income (Loss) (per GAAP) $ (654) $ 155 Adjustments to Net Income (Loss): Interest expense 1,364 1,593 Amortization of intangibles 1,725 2,026 Income tax expense (benefit) (825) 174 Depreciation 3,979 3,585 EBITDA $ 5,589 $ 7,533 Further adjustments to EBITDA: Non-cash stock based compensation 1,130 703 Facility moving expenses 351 - Adjusted EBITDA (non-GAAP) $ 7,070 $ 8,236
  • 29. Confidential Reconciliation of GAAP Net Income to Adjusted Net Income & GAAP Diluted EPS to Adjusted Diluted EPS 29 Reconciliation of GAAP Net Income Available to Common Stockholders to Non-GAAP Adjusted Net Income and GAAP Earnings per Share to Non-GAAP Adjusted Earnings per Share (Unaudited, in thousands) For the Three-Months Ended March 31, 2017 2016 Net loss available to common shareholders (GAAP) $ (3,220) $ (5,412) Adjustments to Net Loss: Amortization of intangibles 1,725 2,026 Non-cash stock-based compensation expenses 1,130 703 Deemed dividends/ PIK dividends on preferred stock 894 1,840 Facility moving expenses 351 - Amortization of preferred stock beneficial conversion feature 1,672 3,727 Adjusted net income (non-GAAP) $ 2,552 $ 2,884 Net loss per common share (GAAP) Diluted EPS $ (0.04) $ (0.07) Adjustments to diluted loss per share: Amortization of intangibles 0.02 0.02 Non-cash stock-based compensation expenses 0.01 0.01 Deemed dividends/ PIK dividends on preferred stock 0.01 0.02 Facility moving expenses - - Amortization of preferred stock beneficial conversion feature 0.02 0.04 Impact of including preferred shares and stock options/warrants in Adj. Diluted Shares (3) 0.01 0.01 Adjusted Diluted EPS (non-GAAP) 0.03 0.03
  • 30. Confidential “Adjusted EBITDA” is defined by NeoGenomics as net income from continuing operations before: (i) interest expense, (ii) tax expense, (iii) depreciation and amortization expense, (iv) non-cash, stock-based compensation expense, and if applicable in a reporting period (v) acquisition related transaction expenses and other significant non-recurring or non-operating (income) or expenses. “Adjusted Net Income” is defined by NeoGenomics as net income available to common shareholders from continuing operations plus: (i) non-cash amortization of customer lists and other intangible assets, (ii) non-cash, stock-based compensation expense, (iii) non-cash deemed dividends on preferred stock, (iv) non-cash amortization of preferred stock beneficial conversion feature, and if applicable in a reporting period (v) acquisition related transaction expenses and other significant non-recurring or non-operating (income) or expenses. “Adjusted Diluted EPS” is defined by NeoGenomics as Adjusted Net Income divided by Adjusted Diluted Shares outstanding. Adjusted Diluted Shares outstanding is the sum of Diluted shares outstanding and the weighted average number of common shares that would be outstanding if the preferred stock were converted into common stock on the original issue date based on the number of days such common shares would have been outstanding in the reporting period. In addition, If GAAP Net Income is negative and Adjusted Net Income is positive, Adjusted Diluted Shares will also include any options or warrants that would be outstanding as dilutive instruments using the treasury stock method. Reconciliation of GAAP Net Income to Adjusted Figures 30 Weighted average shares used in computation of adjusted diluted earnings per share: Diluted Common Shares (GAAP) 78,650 76,068 Options & warrants not included in GAAP Diluted Shares (using treasury stock method) 1,693 2,271 Weighted Avg. Preferred Shares (as converted) 6,600 14,667 Adjusted Diluted Shares outstanding (non-GAAP) 86,943 93,006 For the Three-Months Ended March 31, 2017 2016