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Hassan Chamsi-Pasha
Consultant Cardiologist
FRCP (Lond) , FRCP (Glasg), FRCP (Ire) ,
FACC
Evidence-based
medical benefits of
Siwak
The Prophet PBUH said:
“Had I not feared burdening my Ummah, I
would have commanded them to use
Siwak before every Salat”."
[Al-Bukhari and Muslim].
• The Prophet (PBUH) said, "The
Siwak cleanses and purifies the
mouth, and pleases the Lord"
[An-Nasa'i and Ibn Khuzaimah]
'A'isha reported:
"Whenever Allah's Messenger (PBUH)
entered his house, he used Miswak first of
all". Sahih Muslim
“Whenever the Messenger of Allah
(PBUH) got up (from sleep), he would
rub his teeth with Miswak”.
[Al-Bukhari and Muslim].
• The botanical name of
Miswak is Salvodera
Persica.
• Salvodera Persica is
well known as “Tooth
brush tree”.
• Among 180 plant
species suitable for
preparing toothbrushing
sticks, Miswak
harvested from
Salvadora persica, is
used most extensively.
IJADS 2017; 3(2): 66-70
•‫هناك‬180‫يمكن‬ ‫نبات‬
‫في‬ ‫استخدامها‬
‫السواك‬..
•‫ا‬‫ل‬‫استعما‬ ‫أكثرها‬ ‫ولكن‬
‫شجرة‬ ‫من‬ ‫يؤخذ‬ ‫ما‬ ‫هو‬
‫األراك‬..
Salvadora Persica Tree
‫األراك‬ ‫شجرة‬
‫المسواك‬‫من‬‫جذور‬‫شجرة‬‫األرا‬‫ك‬
Distribution of Salvadora persica
Bioactive components of miswak and their effects
on oral health .‫الفم‬ ‫صحة‬ ‫على‬ ‫وتأثيراتها‬ ‫المسواك‬ ‫في‬ ‫الفعالة‬ ‫المواد‬
Saudi Med J 2015; Vol. 36 (5): 530-543
Journal of Ethnopharmacology 2018,213: 409–444
Cysteine protease was purified
and characterized from miswak
roots, suggesting the use of this
enzyme in toothpaste in the
future.
Proteases in medicinal plants
have different therapeutic effects
such as anti inflammatory effect;
modulate immune response and
inhibitory effect toward tumor
growth.
BMC Biochemistry (2018) 19:10
‫ا‬‫ا‬‫حديث‬ ‫تم‬‫انزيم‬ ‫عزل‬
‫ف‬ ‫بروتياز‬ ‫سيستين‬‫ي‬
‫المسواك‬..‫خصائص‬ ‫وله‬
‫لإللتهاب‬ ‫مضادة‬..
‫لألورام‬ ‫ومثبطة‬..
‫في‬ ‫استخدامه‬ ‫ويمكن‬
‫في‬ ‫األسنان‬ ‫معاجين‬
‫المستقبل‬
A number of scientific
studies have demonstrated
that miswak possesses
antibacterial, anti-fungal,
anti-viral, anti-cariogenic, and
anti-plaque properties.
Several studies have also
claimed that miswak has anti-
oxidant, analgesic, and anti-
inflammatory effects.
Saudi Med J 2015; Vol. 36 (5): 530-543
•‫الدراسات‬ ‫من‬ ‫العديد‬ ‫أظهرت‬
‫يمتلك‬ ‫المسواك‬ ‫أن‬ ‫العلمية‬
‫خصائص‬:
–‫للجراثيم‬ ‫مضادة‬
–‫للفيروسات‬ ‫مضادة‬
–‫للفطور‬ ‫مضادة‬
–‫األسنان‬ ‫لتسوس‬ ‫مضادة‬
–‫األسنان‬ ‫لقلح‬ ‫مضادة‬
–‫لألكسدة‬ ‫مضادة‬
–‫لإللتهابات‬ ‫مضادة‬
Several clinical studies
have confirmed that
the mechanical and
chemical cleansing
efficacy of miswak
chewing sticks are
equal and at times
greater than that of the
toothbrush.
•‫من‬ ‫العديد‬ ‫أكدت‬
‫أن‬ ‫السريرية‬ ‫الدراسات‬
‫المسواك‬ ‫قدرة‬
‫والكيميا‬ ‫الميكانيكية‬‫ئية‬
‫األسنان‬ ‫تنظيف‬ ‫في‬
‫على‬ ‫تتفوق‬ ‫بل‬ ‫تعادل‬
‫بع‬ ‫في‬ ‫األسنان‬ ‫فرشاة‬‫ض‬
‫األحيان‬.
Saudi Med J 2015; Vol. 36 (5): 530-543
Miswak:
Potent Antibacterial
‫السواك‬:‫للجراثيم‬ ‫مضاد‬
Benzyl isothocyanate is the major
active antibacterial metabolite in
S.persica roots ‘‘Siwak”
Cold extraction of fresh samples
with chloroform offers maximum
amount of benzyl isothiocyanate.
Drying process leads to great loss
of the active component of Siwak.
Saudi Pharmaceutical Journal (2019) 753–755
‫مركب‬"‫سياني‬ ‫أيزو‬ ‫بنزيل‬‫ت‬"
‫األساسية‬ ‫الفعالة‬ ‫المادة‬ ‫هو‬
‫جذور‬ ‫في‬ ‫للجراثيم‬ ‫المضادة‬
‫السواك‬.
‫خاصة‬ ‫طرق‬ ‫اتباع‬ ‫من‬ ‫بد‬ ‫ول‬
‫السواك‬ ‫خالصة‬ ‫تحضير‬ ‫عند‬
‫هذه‬ ‫فعالية‬ ‫على‬ ‫للمحافظة‬
‫للجراثيم‬ ‫المضادة‬ ‫المادة‬..
Antibiofilm and
antimicrobial activities of
fresh and dried roots
against S. mutans, a
dental caries causing
bacteria, were determined
using multiple assays.
‫المضادة‬ ‫الفعالية‬ ‫دراسة‬ ‫تمت‬
‫األراك‬ ‫لجذور‬ ‫للميكروبات‬
‫والمجففة‬ ‫الطازجة‬..‫وذلك‬
‫العقدي‬ ‫المكورات‬ ‫جرثومة‬ ‫ضد‬‫ة‬
‫ميوتانس‬..‫تسبب‬ ‫والتي‬
‫األسنان‬ ‫تسوس‬..‫مقايي‬ ‫في‬‫س‬
‫مختلفة‬.
Pathogens. 2020;9(1):E66.
Published 2020 Jan 16.
The results show robust
bactericidal and antibiofilm
activity of S. persica
against S. mutans
comparable to Chlorhexidine.
These essential oils as
effective as CHX and can
serve as a good alternative
antimicrobial agent for oral
hygiene.
‫وجود‬ ‫الدراسة‬ ‫نتائج‬ ‫أظهرت‬
‫كق‬ ‫األراك‬ ‫لخالصة‬ ‫قوية‬ ‫فعالية‬‫اتل‬
‫جرثو‬ ‫لترسب‬ ‫ومضاد‬ ‫للجراثيم‬‫مة‬
‫ميوتانس‬ ‫العقدية‬ ‫المكورات‬..
‫كلور‬ ‫محلول‬ ‫مع‬ ‫بالمقارنة‬ ‫وذلك‬
‫هكسيدين‬.
‫فع‬ ‫الزيوت‬ ‫هذه‬ ُ‫فعالية‬ ‫تعادل‬ ‫و‬َ‫الية‬
‫هكسيدين‬ ‫الكلور‬..‫أن‬ ‫ويمكن‬
‫بدي‬ ‫للجراثيم‬ ‫كمضاد‬ ‫تستخدم‬‫عنه‬ ٍ‫ل‬
‫الفم‬ ‫صحة‬ ‫على‬ ‫المحافظة‬ ‫في‬.
Pathogens. 2020;9(1):E66.
Published 2020 Jan 16.
The pure Salvadora persica
extract (SPE) and SPE-
activated nanocomposites
showed good antibacterial
effect against both
Staphylococcus aureus and
Escherichia coli bacteria.
‫خالصة‬ ‫أظهراستخدام‬
‫وتلك‬ ‫الصافية‬ ‫األراك‬
‫المستخلصة‬‫بتقنية‬"‫ال‬‫نانو‬"
‫الحديثة‬..‫تأثيرات‬ ‫وجود‬
‫جرثوم‬ ‫من‬ ٍ‫ل‬‫لك‬ ‫مضادة‬
‫العنقودية‬ ‫المكورات‬
‫القولوني‬ ‫واإليشيريشيا‬‫ة‬..
The antimicrobial effects
of miswak towards
intraoral microbes can
reduce the prevalence of
denture-induced stomatitis
when used by denture
wearers.
J Indian Prosthodontic Society October 2018
‫تأثيرات‬ ‫أن‬ ‫الباحثون‬ ‫وجد‬
‫للميكروبات‬ ‫المضادة‬ ‫المسواك‬
‫يمكن‬ ‫الفم‬ ‫داخل‬ ‫في‬ ‫الموجودة‬
‫أن‬‫الف‬ ‫التهاب‬ ‫حدوث‬ ‫من‬ ‫تقلل‬‫م‬
‫استخدام‬ ‫عن‬ ‫الناجم‬
‫األسنان‬ ‫طقم‬..
Miswak: Antiplaque
‫األسنان‬ ‫لقلح‬ ‫مضاد‬ ‫السواك‬
The study compared two herbal
toothpastes (Meswak extract and
tea tree oil and analyzed their
efficiency in reducing plaque
accumulation.
25 patients assigned a plaque
score. Brushing with Meswak-based
toothpaste gave a significant drop
in plaque score when compared
wit tea tree oil-based paste.
‫تأثير‬ ‫مقارنة‬ ‫تمت‬‫معجون‬
‫السواك‬ ‫خالصة‬ ‫من‬ ‫أسنان‬..
‫زيت‬ ‫من‬ ‫أسنان‬ ‫بمعجون‬
‫عند‬ ‫الشاي‬ ‫شجرة‬25
‫شخص‬..‫استخ‬ ‫أن‬ ‫فتبين‬‫دام‬
‫األفض‬ ‫كان‬ ‫السواك‬ ‫معجون‬‫ل‬
‫في‬‫قل‬ ‫حدوث‬ ‫معدل‬ ‫تقليل‬‫ح‬
‫األسنان‬.
• Conclusion: The use of Salvadora
persica extract was associated with a
significant reduction in the plaque score
and cariogenic bacterial count.
•‫حدو‬ ‫معدل‬ ‫في‬ ‫مهم‬ ‫انخفاض‬ ‫إلى‬ ‫ّى‬‫د‬‫أ‬ ‫األراك‬ ‫خالصة‬ ‫استعمال‬‫ث‬
‫األسنان‬ ‫قلح‬..‫األ‬ ‫لتسوس‬ ‫المسببة‬ ‫الجراثيم‬ ‫عدد‬ ‫وخفض‬‫سنان‬.
BMC Oral Health (2019) 19:64
19 studies were included in
the meta-analysis.
Salvadora persica rinses
exhibited strong antiplaque
effects (P<0.00001,95% CI:
0.29 to 0.63).
It had significant anti-
streptococcal (P<0.0001)
and anti-lactobacilli effects
(P<0.00001) when
compared to placebo.
‫التحليلية‬ ‫الدراسة‬ ‫شملت‬
19‫سابقة‬ ‫دراسة‬.
‫استخدام‬ ‫أظهر‬ ‫وقد‬‫غسول‬
‫األراك‬‫مضا‬ ‫قوية‬ ‫تأثيرات‬‫دة‬
‫األسنان‬ ‫لقلح‬..
‫ضد‬ ‫مهم‬ ‫تأثير‬ ‫له‬ ‫أن‬ ‫كما‬
‫جراثيم‬‫العقدية‬ ‫المكورات‬
‫اللبنية‬ ‫والعصيات‬‫بالمق‬‫ارنة‬
‫وهمي‬ ‫غسول‬ ‫مع‬..
BMC Oral Health (2019) 19:64
Salvadora persica-
containing rinse could be
considered as a suitable
oral hygiene alternative
for use in individuals of all
ages, socioeconomic
backgrounds, and health
conditions, especially as a
long-term measure due to
its efficacy, safety,
availability, cost-
effectiveness, and ease of
use.
BMC Oral Health (2019) 19:64
‫أن‬ ‫إلى‬ ‫الدراسة‬ ‫خلصت‬‫غسول‬
‫خالصة‬ ‫على‬ ‫الحاوي‬ ‫األسنان‬
‫السواك‬‫مناس‬ ‫ا‬‫ال‬‫بدي‬ ‫يعتبر‬‫ا‬‫ا‬‫ب‬
‫على‬ ‫المحافظة‬ ‫في‬ ‫إلستخدامه‬
‫الفم‬ ‫صحة‬..‫كل‬ ‫عند‬
‫األشخاص‬..‫اختالف‬ ‫على‬
‫أعمارهم‬..‫وخلفيتهم‬
‫اإلجتماعية‬..‫وحالتهم‬
‫الصحية‬..‫كوسيلة‬ ‫وخاصة‬
‫الطويل‬ ‫المدى‬ ‫على‬ ‫تسخدم‬..
‫بسبب‬ ‫وذلك‬‫فعاليتها‬..‫وأما‬‫نها‬
..‫وتوفرها‬..‫وجدواها‬
‫اإلقتصادية‬..‫وسهولة‬
‫استخدامها‬..
BMC Oral Health (2019) 19:64
Miswak and Peridontitis
& Gingivitis:
‫اللثة‬ ‫ومرض‬ ‫السواك‬
Gingivitis and Periodontitis
• Gingivitis and Periodontitis are
both periodontal diseases.
• The major difference between
the two is that gingivitis is
reversible, while periodontitis
is not.
• The reason for that is that there
is permanent damage and loss
of bone in periodontitis, that
cannot be recovered.
73 patients studied to assess
the clinical efficacy of
photodynamic therapy (PDT)
and Salvadora persica (SP) gel
as adjuncts to scaling and root
planning (SRP) in the treatment
of chronic periodontitis.
Three groups: Group I (PDT +
SRP), Group II (SP + SRP) and
group III (SRP alone).
Photodiagnosis Photodyn Ther. 2020 Jan 21.
‫على‬ ‫دراسة‬ ‫أجريت‬73
‫فعالية‬ ‫لمعرفة‬ ‫مريض‬
‫وهالم‬ ‫الضوئية‬ ‫المعالجة‬
‫السواك‬..‫كرديف‬
‫المع‬ ‫ة‬ّ‫ي‬‫السن‬ ‫للمعالجة‬‫تادة‬
‫اللثة‬ ‫مرض‬ ‫عالج‬ ‫في‬
‫المزمن‬..
‫ثالث‬ ‫إلى‬ ‫المرضى‬ ‫قسم‬
‫مجموعات‬..
A significant
improvement in bleeding
on probing (BOP) seen
in Group II compared
with other groups (p <
0.05).
S.Persica significantly
reduced the bleeding
levels.
‫هناك‬ ‫كان‬‫واضح‬ ‫تحسن‬
‫اللث‬ ‫جس‬ ‫عند‬ ‫النزف‬ ‫في‬‫ة‬
‫التي‬ ‫المجموعة‬ ‫في‬
‫السو‬ ‫هالم‬ ‫فيها‬ ‫خدم‬ُ‫ت‬‫اس‬‫اك‬
‫السنية‬ ‫المعالجة‬ ‫مع‬
‫المعتادة‬..
‫وقد‬‫هال‬ ‫استخدام‬ ‫ض‬ّ‫ف‬‫خ‬‫م‬
‫نزف‬ ‫معدلت‬ ‫من‬ ‫السواك‬
‫اللثة‬..
Photodiagnosis Photodyn Ther. 2020 Jan 21
Miswak & Caries
‫األسنان‬ ‫وتسوس‬ ‫السواك‬
• Dental caries is a biofilm-
induced oral disease with S.
mutans playing a key role in
the development of virulent
cariogenic biofilms.
• Decreasing the bacterial
burden of the oral cavity is
one of the fundamental
biological goals in preventing
dental caries.
•‫تسوس‬ ‫ينجم‬(‫نخر‬)‫تكدس‬ ‫ذلك‬ ‫في‬ ‫بما‬ ،‫العوامل‬ ‫من‬ ‫مجموعة‬ ‫عن‬ ‫األسنان‬
‫األسنان‬ ‫سطح‬ ‫على‬ ‫الفم‬ ‫في‬ ‫البكتيريا‬.
•‫ت‬ ‫من‬ ‫الوقاية‬ ‫في‬ ‫مهما‬ ‫ا‬‫ا‬‫دور‬ ‫يلعب‬ ‫الفم‬ ‫في‬ ‫الجراثيم‬ ‫كمية‬ ‫خفض‬ ‫أن‬ ‫لشك‬‫سوس‬
‫األسنان‬..
A study was conducted
among 213 males, aged 20 to
65 years, to evaluate the
periodontal status of Miswak
and toothbrush users.
They reported that
periodontal status of Miswak
users in Sudanese
population is better than that
of toothbrush.
•‫على‬ ‫أجريت‬ ‫دراسة‬ ‫وفي‬213
‫تراوحت‬ ‫السودان‬ ‫في‬ ‫شخص‬
‫بين‬ ‫أعمارهم‬20-65‫سنة‬..
‫عند‬ ‫اللثة‬ ‫حالة‬ ‫فيها‬ ‫قورنت‬
‫ومستخدمي‬ ‫السواك‬ ‫مستخدمي‬
‫األسنان‬ ‫فرشاة‬..
•‫الصح‬ ‫اللثة‬ ‫وضع‬ ‫أن‬ ‫فتبين‬‫ي‬
‫مستخدمي‬ ‫عند‬ ‫أفضل‬ ‫كان‬
‫السواك‬..
Miswak: Antifungal
‫السواك‬:‫للفطور‬ ‫مضاد‬
The current study revealed that
the aqueous extract of S.
persica miswak showed strong
fungicidal impact against
Aspergillus species.
This may support the utilization
of this extract as an antifungal
agent in aspergillosis-related
diseases.
Dose-Response: July-September 2019:1-5
‫خالصة‬ ‫أن‬ ‫مخبرية‬ ‫دراسة‬ ‫أظهرت‬
‫المائية‬ ‫السواك‬‫قوي‬ ‫تأثير‬ ‫وجود‬
‫الرشاشيات‬ ‫لفطر‬ ‫مضاد‬
(‫أسبرجيللس‬..)
‫الخالص‬ ‫تلك‬ ‫استخدام‬ ‫ذلك‬ ‫يدعم‬ ‫وقد‬‫ة‬
‫في‬ ‫الفطور‬ ‫لمضادات‬ ‫كمساعد‬
‫الرشاشيات‬ ‫فطر‬ ‫أمراض‬..
‫من‬ ‫مزيد‬ ‫إلى‬ ‫األمر‬ ‫ويحتاج‬
‫الدراسات‬
Miswak: Antioxidant
‫لألكسدة‬ ‫مضاد‬ ‫السواك‬
A new sulphur-containing
imidazoline alkaloid, persicaline,
along with five known
compounds was identified.
It showed reasonable antioxidant
activity.
Future investigation of bioactive
compounds from S. persica for
formulation of new bio-products
is highly recommended.
Molecules 2018, 23, 483;
‫عن‬ ‫الكشف‬ ‫تم‬‫مركب‬ ‫وجود‬
‫في‬ ‫لألكسدة‬ ‫مضاد‬ ‫جديد‬
‫يدعى‬ ‫المسواك‬"‫برسيكالين‬"‫في‬
‫األراك‬ ‫شجرة‬ ‫جذور‬..
‫إلى‬ ‫إضافة‬ ‫وذلك‬‫مضادات‬ ‫خمس‬
‫معروفة‬ ‫أكسدة‬..
‫من‬ ‫المزيد‬ ‫إجراء‬ ‫من‬ ‫بد‬ ‫ول‬
‫المنتج‬ ‫تلك‬ ‫لتركيب‬ ‫الدراسات‬‫ات‬.
Miswak:
Other effects
‫أخرى‬ ‫فوائد‬
S.Persica aqueous extract alleviated
serious gastric mucosal ulcerations
induced by ethanol and emphasized
its efficacy as an antiulcer
protectant.
The underlying mechanism of its activity is
through the enhancement of the
antioxidative defense system, minimization
of proinflammatory cytokines and apoptotic
pathway, and augmentation of mucus
content.
Oxid Med Cell Longev. 2018;
2018:6703296.
‫على‬ ‫أجريت‬ ‫تجربة‬ ‫كشفت‬
‫خالص‬ ‫استخدام‬ ‫أن‬ ‫الفئران‬‫ة‬
‫قد‬ ‫المائية‬ ‫األراك‬‫فت‬ّ‫ف‬‫خ‬‫من‬
‫المعدة‬ ‫تقرحات‬‫عن‬ ‫الناجمة‬
‫الكحول‬..
‫ا‬‫ا‬‫تأثير‬ ‫لألراك‬ ‫يكون‬ ‫فقد‬
‫المعدة‬ ‫قرحة‬ ‫من‬ ‫ا‬‫ا‬‫واقي‬..
Protective Effects of Miswak (Salvadora
persica) against Experimentally Induced
Gastric Ulcers in Rats
Salvadora persica root extracts
were used to treat helminthosis
and coccideosis.
Three doses were used (200,
100 and 50 mg/ml) to study the
anthelmintic activity of S.Persica
Conclusion: S. persica
possesses a powerful
Anthelmintic, anticoccidial and
antioxidant activity.
‫فيها‬ ‫استعملت‬ ‫دراسة‬ ‫هناك‬
‫معالجة‬ ‫في‬ ‫األراك‬ ‫جذور‬ ‫خالصة‬
‫الطفيليات‬ ‫بعض‬..
Saudi Journal of Biological Sciences September 2019
Miswak serves as a natural
toothpaste with antibacterial,
anti-caries, anti-periopathic
disinfectant having anti-plaque
and anti-fungal properties.
Miswak sticks are being used by
majority of people who cannot
afford to buy the commercial
western toothbrush and
toothpaste mainly in rural areas
of developing countries.
‫يعمل‬‫أسنان‬ ‫كمعجون‬ ‫المسواك‬
‫كم‬ ‫إضافية‬ ‫بخصائص‬ ‫طبيعي‬‫ضاد‬
‫األسنان‬ ‫لنخر‬ ‫ومضاد‬ ‫للجراثيم‬
‫للفطور‬ ‫ومضاد‬ ‫األسنان‬ ‫ولقلح‬..
‫قبل‬ ‫من‬ ‫المسواك‬ ‫ويستخدم‬
‫يستطيعو‬ ‫ل‬ ‫الذين‬ ‫الكثيرين‬‫ن‬
‫ومعاجين‬ ‫األسنان‬ ‫فراشي‬ ‫شراء‬
‫األسنان‬..‫الناطق‬ ‫في‬ ‫وخاصة‬
‫النامية‬ ‫البلدان‬ ‫في‬ ‫النائية‬..
‫أنه‬ ‫الدراسات‬ ‫هذه‬ ‫من‬ ‫يتضح‬
‫يمكن‬‫نب‬ ‫األراك‬ ‫اعتبارشجرة‬‫ا‬‫ا‬‫ات‬
‫م‬ ‫ا‬‫ال‬‫كام‬ ‫ا‬‫ا‬‫درع‬ ‫يمتلك‬ ‫ا‬‫ا‬‫طبي‬‫ن‬
‫الفعالة‬ ‫المركبات‬..‫والخصائ‬‫ص‬
‫الدوائية‬..‫الحد‬ ‫والتطبيقات‬‫يثة‬..
‫الناش‬ ‫المختلفة‬ ‫المجالت‬ ‫في‬‫ئة‬.
Journal of Ethnopharmacology 213 (2018) 409–444
It is obvious from this review
that S. persica can be
regarded as an important
traditionally used medicinal
plant harboring a panoply of
bioactive compounds,
pharmacological properties,
and modern applications in
emerging fields of interest.
Conclusion: S. persica
showed a wide scope of
application and its uses
extended far beyond the
initial traditional uses of its
roots, stems, & twigs in oral
care.
Other ethnopharmacological
uses and potential
applications of different parts
of S. persica warrants further
investigations.
‫الخالصة‬:
‫تطبيقا‬ ‫األراك‬ ‫لشجرة‬ ‫أن‬ ‫لشك‬‫ت‬
‫عديدة‬..‫وأن‬‫تجاوزت‬ ‫استعمالتها‬
‫التقليدي‬ ‫اإلستعمالت‬ ‫بكثير‬‫ة‬
‫المعروفة‬‫األراك‬ ‫شجرة‬ ‫لجذور‬..
‫وجذوعها‬..‫وأغصانها‬..‫في‬ ‫وذلك‬
‫الفم‬ ‫بصحة‬ ‫العناية‬.
‫من‬ ‫العديد‬ ‫وهناك‬‫اإلستعمالت‬
‫شجرة‬ ‫أجزاء‬ ‫لمختلف‬ ‫المحتملة‬
‫األراك‬..‫من‬ ‫المزيد‬ ‫إلى‬ ‫وتحتاج‬
‫األبحاث‬
Journal of Ethnopharmacology 2018,213: 409–444
‫األراك‬ ‫غصين‬ ‫معجزة‬
IJADS 2017; 3(2): 66-70
‫السواك‬ ‫تأكد‬ ‫أوقات‬
1-‫الوضوء‬ ‫عند‬.‫وس‬ ‫عليه‬ ‫هللا‬ ‫صلى‬ ‫النبي‬ ‫عن‬ ‫عنه‬ ‫هللا‬ ‫رضى‬ ‫هريرة‬ ‫أبي‬ ‫لحديث‬‫قال‬ ‫لم‬:
(‫وضوء‬ ‫كل‬ ‫عند‬ ‫بالسواك‬ ‫ألمرتهم‬ ‫أمتي‬ ‫على‬ ‫أشق‬ ‫أن‬ ‫لول‬)‫البخاري‬ ‫رواه‬.
2-‫للصالة‬ ‫القيام‬ ‫عند‬.‫هللا‬ ‫صلى‬ ‫هللا‬ ‫رسول‬ ‫أن‬ ‫عنه‬ ‫هللا‬ ‫رضى‬ ‫هريرة‬ ‫أبي‬ ‫لحديث‬‫عليه‬
‫قال‬ ‫وسلم‬( :‫صالة‬ ‫كل‬ ‫مع‬ ‫بالسواك‬ ‫ألمرتهم‬ ‫الناس‬ ‫على‬ ‫أو‬ ‫أمتي‬ ‫على‬ ‫أشق‬ ‫أن‬ ‫لول‬)‫الب‬‫خاري‬
3-‫النوم‬ ‫من‬ ‫القيام‬ ‫عند‬.‫قال‬ ‫عنه‬ ‫هللا‬ ‫رضى‬ ‫حذيفة‬ ‫لحديث‬( :‫هللا‬ ‫صلى‬ ‫النبي‬ ‫كان‬‫عليه‬
‫بالسواك‬ ‫فاه‬ ‫يشوص‬ ‫الليل‬ ‫من‬ ‫قام‬ ‫إذا‬ ‫وسلم‬)‫البخاري‬ ‫رواه‬.
4-‫المنزل‬ ‫دخول‬ ‫عند‬.‫عنها‬ ‫هللا‬ ‫رضي‬ ‫عائشة‬ ‫لحديث‬(‫وس‬ ‫عليه‬ ‫هللا‬ ‫صلى‬ ‫النبي‬ ‫أن‬‫كان‬ ‫لم‬
‫بالسواك‬ ‫بدأ‬ ‫بيته‬ ‫دخل‬ ‫إذا‬)‫مسلم‬ ‫رواه‬
5-‫األسنان‬ ‫واصفرار‬ ‫الفم‬ ‫تغير‬ ‫عند‬.‫عنها‬ ‫هللا‬ ‫رضي‬ ‫عائشة‬ ‫لحديث‬(‫ص‬ ‫النبي‬ ‫أن‬‫هللا‬ ‫لى‬
‫قال‬ ‫وسلم‬ ‫عليه‬:‫للرب‬ ‫مرضاة‬ ‫للفم‬ ‫مطهرة‬ ‫السواك‬)‫البخاري‬ ‫رواه‬.
6-‫الكريم‬ ‫القرآن‬ ‫قراءة‬ ‫عند‬:‫وسلم‬ ‫عليه‬ ‫هللا‬ ‫صلى‬ ‫قال‬( :‫ثم‬ ‫تسوك‬ ‫إذا‬ ‫العبد‬ ‫إن‬‫قام‬
‫منه‬ ‫فيدنو‬ ‫قراءته‬ ‫إلى‬ ‫فيستمع‬ ‫خلفه‬ ‫الملك‬ ‫قام‬ ‫يصلي‬-‫نحوها‬ ‫كلمة‬ ‫أو‬-‫ي‬ ‫حتى‬‫فاه‬ ‫ضع‬
‫أفواهك‬ ‫فطهروا‬ ‫الملك‬ ‫جوف‬ ‫في‬ ‫صار‬ ‫إل‬ ‫القرآن‬ ‫من‬ ‫شىء‬ ‫فيه‬ ‫من‬ ‫يخرج‬ ‫فما‬ ‫فيه‬ ‫على‬‫م‬
‫للقرآن‬)‫البيهقي‬ ‫رواه‬.‫ثقات‬ ‫رجاله‬ ‫البزار‬ ‫وقال‬.
•‫هللا‬ ‫رضي‬ ‫الزهراء‬ ‫فاطمة‬ ‫زوجته‬ ‫على‬ ‫طالب‬ ‫أبي‬ ‫بن‬ ُّ‫ي‬‫عل‬ ‫دخل‬
‫عنهما‬..‫أراك‬ ْ‫من‬ ٍ‫بسواك‬ ‫تستاك‬ ‫فرآها‬..‫بي‬ ‫في‬ ‫لها‬ ‫فقال‬‫تين‬
‫عجيبين‬ ‫جميلين‬:
‫بثغرها‬ ِ‫األراك‬ َ‫د‬‫عو‬ ‫يا‬ َ‫حظيت‬...‫األ‬ َ‫د‬‫عو‬ ‫يا‬ َ‫ت‬ْ‫ف‬‫خ‬ ‫أما‬َ‫أراك‬ ِ‫راك‬
َ‫ك‬ُ‫ت‬ْ‫ل‬‫قت‬ ‫القتال‬ ِ‫ل‬‫أه‬ ْ‫من‬ َ‫كنت‬ ‫لو‬...ِ‫س‬ ‫يا‬ ‫مني‬ َ‫فاز‬ ‫ما‬َ‫واك‬ِ‫س‬ ُ‫واك‬
https://www.drchamsipasha.com

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Siwak miracles dr.hassan chamsi pasha

  • 1. Hassan Chamsi-Pasha Consultant Cardiologist FRCP (Lond) , FRCP (Glasg), FRCP (Ire) , FACC Evidence-based medical benefits of Siwak
  • 2. The Prophet PBUH said: “Had I not feared burdening my Ummah, I would have commanded them to use Siwak before every Salat”." [Al-Bukhari and Muslim].
  • 3. • The Prophet (PBUH) said, "The Siwak cleanses and purifies the mouth, and pleases the Lord" [An-Nasa'i and Ibn Khuzaimah]
  • 4. 'A'isha reported: "Whenever Allah's Messenger (PBUH) entered his house, he used Miswak first of all". Sahih Muslim
  • 5. “Whenever the Messenger of Allah (PBUH) got up (from sleep), he would rub his teeth with Miswak”. [Al-Bukhari and Muslim].
  • 6. • The botanical name of Miswak is Salvodera Persica. • Salvodera Persica is well known as “Tooth brush tree”. • Among 180 plant species suitable for preparing toothbrushing sticks, Miswak harvested from Salvadora persica, is used most extensively. IJADS 2017; 3(2): 66-70 •‫هناك‬180‫يمكن‬ ‫نبات‬ ‫في‬ ‫استخدامها‬ ‫السواك‬.. •‫ا‬‫ل‬‫استعما‬ ‫أكثرها‬ ‫ولكن‬ ‫شجرة‬ ‫من‬ ‫يؤخذ‬ ‫ما‬ ‫هو‬ ‫األراك‬..
  • 10. Bioactive components of miswak and their effects on oral health .‫الفم‬ ‫صحة‬ ‫على‬ ‫وتأثيراتها‬ ‫المسواك‬ ‫في‬ ‫الفعالة‬ ‫المواد‬ Saudi Med J 2015; Vol. 36 (5): 530-543
  • 11. Journal of Ethnopharmacology 2018,213: 409–444
  • 12. Cysteine protease was purified and characterized from miswak roots, suggesting the use of this enzyme in toothpaste in the future. Proteases in medicinal plants have different therapeutic effects such as anti inflammatory effect; modulate immune response and inhibitory effect toward tumor growth. BMC Biochemistry (2018) 19:10 ‫ا‬‫ا‬‫حديث‬ ‫تم‬‫انزيم‬ ‫عزل‬ ‫ف‬ ‫بروتياز‬ ‫سيستين‬‫ي‬ ‫المسواك‬..‫خصائص‬ ‫وله‬ ‫لإللتهاب‬ ‫مضادة‬.. ‫لألورام‬ ‫ومثبطة‬.. ‫في‬ ‫استخدامه‬ ‫ويمكن‬ ‫في‬ ‫األسنان‬ ‫معاجين‬ ‫المستقبل‬
  • 13. A number of scientific studies have demonstrated that miswak possesses antibacterial, anti-fungal, anti-viral, anti-cariogenic, and anti-plaque properties. Several studies have also claimed that miswak has anti- oxidant, analgesic, and anti- inflammatory effects. Saudi Med J 2015; Vol. 36 (5): 530-543 •‫الدراسات‬ ‫من‬ ‫العديد‬ ‫أظهرت‬ ‫يمتلك‬ ‫المسواك‬ ‫أن‬ ‫العلمية‬ ‫خصائص‬: –‫للجراثيم‬ ‫مضادة‬ –‫للفيروسات‬ ‫مضادة‬ –‫للفطور‬ ‫مضادة‬ –‫األسنان‬ ‫لتسوس‬ ‫مضادة‬ –‫األسنان‬ ‫لقلح‬ ‫مضادة‬ –‫لألكسدة‬ ‫مضادة‬ –‫لإللتهابات‬ ‫مضادة‬
  • 14. Several clinical studies have confirmed that the mechanical and chemical cleansing efficacy of miswak chewing sticks are equal and at times greater than that of the toothbrush. •‫من‬ ‫العديد‬ ‫أكدت‬ ‫أن‬ ‫السريرية‬ ‫الدراسات‬ ‫المسواك‬ ‫قدرة‬ ‫والكيميا‬ ‫الميكانيكية‬‫ئية‬ ‫األسنان‬ ‫تنظيف‬ ‫في‬ ‫على‬ ‫تتفوق‬ ‫بل‬ ‫تعادل‬ ‫بع‬ ‫في‬ ‫األسنان‬ ‫فرشاة‬‫ض‬ ‫األحيان‬. Saudi Med J 2015; Vol. 36 (5): 530-543
  • 16. Benzyl isothocyanate is the major active antibacterial metabolite in S.persica roots ‘‘Siwak” Cold extraction of fresh samples with chloroform offers maximum amount of benzyl isothiocyanate. Drying process leads to great loss of the active component of Siwak. Saudi Pharmaceutical Journal (2019) 753–755 ‫مركب‬"‫سياني‬ ‫أيزو‬ ‫بنزيل‬‫ت‬" ‫األساسية‬ ‫الفعالة‬ ‫المادة‬ ‫هو‬ ‫جذور‬ ‫في‬ ‫للجراثيم‬ ‫المضادة‬ ‫السواك‬. ‫خاصة‬ ‫طرق‬ ‫اتباع‬ ‫من‬ ‫بد‬ ‫ول‬ ‫السواك‬ ‫خالصة‬ ‫تحضير‬ ‫عند‬ ‫هذه‬ ‫فعالية‬ ‫على‬ ‫للمحافظة‬ ‫للجراثيم‬ ‫المضادة‬ ‫المادة‬..
  • 17. Antibiofilm and antimicrobial activities of fresh and dried roots against S. mutans, a dental caries causing bacteria, were determined using multiple assays. ‫المضادة‬ ‫الفعالية‬ ‫دراسة‬ ‫تمت‬ ‫األراك‬ ‫لجذور‬ ‫للميكروبات‬ ‫والمجففة‬ ‫الطازجة‬..‫وذلك‬ ‫العقدي‬ ‫المكورات‬ ‫جرثومة‬ ‫ضد‬‫ة‬ ‫ميوتانس‬..‫تسبب‬ ‫والتي‬ ‫األسنان‬ ‫تسوس‬..‫مقايي‬ ‫في‬‫س‬ ‫مختلفة‬. Pathogens. 2020;9(1):E66. Published 2020 Jan 16.
  • 18. The results show robust bactericidal and antibiofilm activity of S. persica against S. mutans comparable to Chlorhexidine. These essential oils as effective as CHX and can serve as a good alternative antimicrobial agent for oral hygiene. ‫وجود‬ ‫الدراسة‬ ‫نتائج‬ ‫أظهرت‬ ‫كق‬ ‫األراك‬ ‫لخالصة‬ ‫قوية‬ ‫فعالية‬‫اتل‬ ‫جرثو‬ ‫لترسب‬ ‫ومضاد‬ ‫للجراثيم‬‫مة‬ ‫ميوتانس‬ ‫العقدية‬ ‫المكورات‬.. ‫كلور‬ ‫محلول‬ ‫مع‬ ‫بالمقارنة‬ ‫وذلك‬ ‫هكسيدين‬. ‫فع‬ ‫الزيوت‬ ‫هذه‬ ُ‫فعالية‬ ‫تعادل‬ ‫و‬َ‫الية‬ ‫هكسيدين‬ ‫الكلور‬..‫أن‬ ‫ويمكن‬ ‫بدي‬ ‫للجراثيم‬ ‫كمضاد‬ ‫تستخدم‬‫عنه‬ ٍ‫ل‬ ‫الفم‬ ‫صحة‬ ‫على‬ ‫المحافظة‬ ‫في‬. Pathogens. 2020;9(1):E66. Published 2020 Jan 16.
  • 19. The pure Salvadora persica extract (SPE) and SPE- activated nanocomposites showed good antibacterial effect against both Staphylococcus aureus and Escherichia coli bacteria. ‫خالصة‬ ‫أظهراستخدام‬ ‫وتلك‬ ‫الصافية‬ ‫األراك‬ ‫المستخلصة‬‫بتقنية‬"‫ال‬‫نانو‬" ‫الحديثة‬..‫تأثيرات‬ ‫وجود‬ ‫جرثوم‬ ‫من‬ ٍ‫ل‬‫لك‬ ‫مضادة‬ ‫العنقودية‬ ‫المكورات‬ ‫القولوني‬ ‫واإليشيريشيا‬‫ة‬..
  • 20. The antimicrobial effects of miswak towards intraoral microbes can reduce the prevalence of denture-induced stomatitis when used by denture wearers. J Indian Prosthodontic Society October 2018 ‫تأثيرات‬ ‫أن‬ ‫الباحثون‬ ‫وجد‬ ‫للميكروبات‬ ‫المضادة‬ ‫المسواك‬ ‫يمكن‬ ‫الفم‬ ‫داخل‬ ‫في‬ ‫الموجودة‬ ‫أن‬‫الف‬ ‫التهاب‬ ‫حدوث‬ ‫من‬ ‫تقلل‬‫م‬ ‫استخدام‬ ‫عن‬ ‫الناجم‬ ‫األسنان‬ ‫طقم‬..
  • 21. Miswak: Antiplaque ‫األسنان‬ ‫لقلح‬ ‫مضاد‬ ‫السواك‬
  • 22. The study compared two herbal toothpastes (Meswak extract and tea tree oil and analyzed their efficiency in reducing plaque accumulation. 25 patients assigned a plaque score. Brushing with Meswak-based toothpaste gave a significant drop in plaque score when compared wit tea tree oil-based paste. ‫تأثير‬ ‫مقارنة‬ ‫تمت‬‫معجون‬ ‫السواك‬ ‫خالصة‬ ‫من‬ ‫أسنان‬.. ‫زيت‬ ‫من‬ ‫أسنان‬ ‫بمعجون‬ ‫عند‬ ‫الشاي‬ ‫شجرة‬25 ‫شخص‬..‫استخ‬ ‫أن‬ ‫فتبين‬‫دام‬ ‫األفض‬ ‫كان‬ ‫السواك‬ ‫معجون‬‫ل‬ ‫في‬‫قل‬ ‫حدوث‬ ‫معدل‬ ‫تقليل‬‫ح‬ ‫األسنان‬.
  • 23. • Conclusion: The use of Salvadora persica extract was associated with a significant reduction in the plaque score and cariogenic bacterial count. •‫حدو‬ ‫معدل‬ ‫في‬ ‫مهم‬ ‫انخفاض‬ ‫إلى‬ ‫ّى‬‫د‬‫أ‬ ‫األراك‬ ‫خالصة‬ ‫استعمال‬‫ث‬ ‫األسنان‬ ‫قلح‬..‫األ‬ ‫لتسوس‬ ‫المسببة‬ ‫الجراثيم‬ ‫عدد‬ ‫وخفض‬‫سنان‬. BMC Oral Health (2019) 19:64
  • 24. 19 studies were included in the meta-analysis. Salvadora persica rinses exhibited strong antiplaque effects (P<0.00001,95% CI: 0.29 to 0.63). It had significant anti- streptococcal (P<0.0001) and anti-lactobacilli effects (P<0.00001) when compared to placebo. ‫التحليلية‬ ‫الدراسة‬ ‫شملت‬ 19‫سابقة‬ ‫دراسة‬. ‫استخدام‬ ‫أظهر‬ ‫وقد‬‫غسول‬ ‫األراك‬‫مضا‬ ‫قوية‬ ‫تأثيرات‬‫دة‬ ‫األسنان‬ ‫لقلح‬.. ‫ضد‬ ‫مهم‬ ‫تأثير‬ ‫له‬ ‫أن‬ ‫كما‬ ‫جراثيم‬‫العقدية‬ ‫المكورات‬ ‫اللبنية‬ ‫والعصيات‬‫بالمق‬‫ارنة‬ ‫وهمي‬ ‫غسول‬ ‫مع‬.. BMC Oral Health (2019) 19:64
  • 25. Salvadora persica- containing rinse could be considered as a suitable oral hygiene alternative for use in individuals of all ages, socioeconomic backgrounds, and health conditions, especially as a long-term measure due to its efficacy, safety, availability, cost- effectiveness, and ease of use. BMC Oral Health (2019) 19:64 ‫أن‬ ‫إلى‬ ‫الدراسة‬ ‫خلصت‬‫غسول‬ ‫خالصة‬ ‫على‬ ‫الحاوي‬ ‫األسنان‬ ‫السواك‬‫مناس‬ ‫ا‬‫ال‬‫بدي‬ ‫يعتبر‬‫ا‬‫ا‬‫ب‬ ‫على‬ ‫المحافظة‬ ‫في‬ ‫إلستخدامه‬ ‫الفم‬ ‫صحة‬..‫كل‬ ‫عند‬ ‫األشخاص‬..‫اختالف‬ ‫على‬ ‫أعمارهم‬..‫وخلفيتهم‬ ‫اإلجتماعية‬..‫وحالتهم‬ ‫الصحية‬..‫كوسيلة‬ ‫وخاصة‬ ‫الطويل‬ ‫المدى‬ ‫على‬ ‫تسخدم‬.. ‫بسبب‬ ‫وذلك‬‫فعاليتها‬..‫وأما‬‫نها‬ ..‫وتوفرها‬..‫وجدواها‬ ‫اإلقتصادية‬..‫وسهولة‬ ‫استخدامها‬.. BMC Oral Health (2019) 19:64
  • 26. Miswak and Peridontitis & Gingivitis: ‫اللثة‬ ‫ومرض‬ ‫السواك‬
  • 27. Gingivitis and Periodontitis • Gingivitis and Periodontitis are both periodontal diseases. • The major difference between the two is that gingivitis is reversible, while periodontitis is not. • The reason for that is that there is permanent damage and loss of bone in periodontitis, that cannot be recovered.
  • 28. 73 patients studied to assess the clinical efficacy of photodynamic therapy (PDT) and Salvadora persica (SP) gel as adjuncts to scaling and root planning (SRP) in the treatment of chronic periodontitis. Three groups: Group I (PDT + SRP), Group II (SP + SRP) and group III (SRP alone). Photodiagnosis Photodyn Ther. 2020 Jan 21. ‫على‬ ‫دراسة‬ ‫أجريت‬73 ‫فعالية‬ ‫لمعرفة‬ ‫مريض‬ ‫وهالم‬ ‫الضوئية‬ ‫المعالجة‬ ‫السواك‬..‫كرديف‬ ‫المع‬ ‫ة‬ّ‫ي‬‫السن‬ ‫للمعالجة‬‫تادة‬ ‫اللثة‬ ‫مرض‬ ‫عالج‬ ‫في‬ ‫المزمن‬.. ‫ثالث‬ ‫إلى‬ ‫المرضى‬ ‫قسم‬ ‫مجموعات‬..
  • 29. A significant improvement in bleeding on probing (BOP) seen in Group II compared with other groups (p < 0.05). S.Persica significantly reduced the bleeding levels. ‫هناك‬ ‫كان‬‫واضح‬ ‫تحسن‬ ‫اللث‬ ‫جس‬ ‫عند‬ ‫النزف‬ ‫في‬‫ة‬ ‫التي‬ ‫المجموعة‬ ‫في‬ ‫السو‬ ‫هالم‬ ‫فيها‬ ‫خدم‬ُ‫ت‬‫اس‬‫اك‬ ‫السنية‬ ‫المعالجة‬ ‫مع‬ ‫المعتادة‬.. ‫وقد‬‫هال‬ ‫استخدام‬ ‫ض‬ّ‫ف‬‫خ‬‫م‬ ‫نزف‬ ‫معدلت‬ ‫من‬ ‫السواك‬ ‫اللثة‬.. Photodiagnosis Photodyn Ther. 2020 Jan 21
  • 30. Miswak & Caries ‫األسنان‬ ‫وتسوس‬ ‫السواك‬
  • 31. • Dental caries is a biofilm- induced oral disease with S. mutans playing a key role in the development of virulent cariogenic biofilms. • Decreasing the bacterial burden of the oral cavity is one of the fundamental biological goals in preventing dental caries. •‫تسوس‬ ‫ينجم‬(‫نخر‬)‫تكدس‬ ‫ذلك‬ ‫في‬ ‫بما‬ ،‫العوامل‬ ‫من‬ ‫مجموعة‬ ‫عن‬ ‫األسنان‬ ‫األسنان‬ ‫سطح‬ ‫على‬ ‫الفم‬ ‫في‬ ‫البكتيريا‬. •‫ت‬ ‫من‬ ‫الوقاية‬ ‫في‬ ‫مهما‬ ‫ا‬‫ا‬‫دور‬ ‫يلعب‬ ‫الفم‬ ‫في‬ ‫الجراثيم‬ ‫كمية‬ ‫خفض‬ ‫أن‬ ‫لشك‬‫سوس‬ ‫األسنان‬..
  • 32. A study was conducted among 213 males, aged 20 to 65 years, to evaluate the periodontal status of Miswak and toothbrush users. They reported that periodontal status of Miswak users in Sudanese population is better than that of toothbrush. •‫على‬ ‫أجريت‬ ‫دراسة‬ ‫وفي‬213 ‫تراوحت‬ ‫السودان‬ ‫في‬ ‫شخص‬ ‫بين‬ ‫أعمارهم‬20-65‫سنة‬.. ‫عند‬ ‫اللثة‬ ‫حالة‬ ‫فيها‬ ‫قورنت‬ ‫ومستخدمي‬ ‫السواك‬ ‫مستخدمي‬ ‫األسنان‬ ‫فرشاة‬.. •‫الصح‬ ‫اللثة‬ ‫وضع‬ ‫أن‬ ‫فتبين‬‫ي‬ ‫مستخدمي‬ ‫عند‬ ‫أفضل‬ ‫كان‬ ‫السواك‬..
  • 34. The current study revealed that the aqueous extract of S. persica miswak showed strong fungicidal impact against Aspergillus species. This may support the utilization of this extract as an antifungal agent in aspergillosis-related diseases. Dose-Response: July-September 2019:1-5 ‫خالصة‬ ‫أن‬ ‫مخبرية‬ ‫دراسة‬ ‫أظهرت‬ ‫المائية‬ ‫السواك‬‫قوي‬ ‫تأثير‬ ‫وجود‬ ‫الرشاشيات‬ ‫لفطر‬ ‫مضاد‬ (‫أسبرجيللس‬..) ‫الخالص‬ ‫تلك‬ ‫استخدام‬ ‫ذلك‬ ‫يدعم‬ ‫وقد‬‫ة‬ ‫في‬ ‫الفطور‬ ‫لمضادات‬ ‫كمساعد‬ ‫الرشاشيات‬ ‫فطر‬ ‫أمراض‬.. ‫من‬ ‫مزيد‬ ‫إلى‬ ‫األمر‬ ‫ويحتاج‬ ‫الدراسات‬
  • 35.
  • 37. A new sulphur-containing imidazoline alkaloid, persicaline, along with five known compounds was identified. It showed reasonable antioxidant activity. Future investigation of bioactive compounds from S. persica for formulation of new bio-products is highly recommended. Molecules 2018, 23, 483; ‫عن‬ ‫الكشف‬ ‫تم‬‫مركب‬ ‫وجود‬ ‫في‬ ‫لألكسدة‬ ‫مضاد‬ ‫جديد‬ ‫يدعى‬ ‫المسواك‬"‫برسيكالين‬"‫في‬ ‫األراك‬ ‫شجرة‬ ‫جذور‬.. ‫إلى‬ ‫إضافة‬ ‫وذلك‬‫مضادات‬ ‫خمس‬ ‫معروفة‬ ‫أكسدة‬.. ‫من‬ ‫المزيد‬ ‫إجراء‬ ‫من‬ ‫بد‬ ‫ول‬ ‫المنتج‬ ‫تلك‬ ‫لتركيب‬ ‫الدراسات‬‫ات‬.
  • 39. S.Persica aqueous extract alleviated serious gastric mucosal ulcerations induced by ethanol and emphasized its efficacy as an antiulcer protectant. The underlying mechanism of its activity is through the enhancement of the antioxidative defense system, minimization of proinflammatory cytokines and apoptotic pathway, and augmentation of mucus content. Oxid Med Cell Longev. 2018; 2018:6703296. ‫على‬ ‫أجريت‬ ‫تجربة‬ ‫كشفت‬ ‫خالص‬ ‫استخدام‬ ‫أن‬ ‫الفئران‬‫ة‬ ‫قد‬ ‫المائية‬ ‫األراك‬‫فت‬ّ‫ف‬‫خ‬‫من‬ ‫المعدة‬ ‫تقرحات‬‫عن‬ ‫الناجمة‬ ‫الكحول‬.. ‫ا‬‫ا‬‫تأثير‬ ‫لألراك‬ ‫يكون‬ ‫فقد‬ ‫المعدة‬ ‫قرحة‬ ‫من‬ ‫ا‬‫ا‬‫واقي‬..
  • 40. Protective Effects of Miswak (Salvadora persica) against Experimentally Induced Gastric Ulcers in Rats
  • 41. Salvadora persica root extracts were used to treat helminthosis and coccideosis. Three doses were used (200, 100 and 50 mg/ml) to study the anthelmintic activity of S.Persica Conclusion: S. persica possesses a powerful Anthelmintic, anticoccidial and antioxidant activity. ‫فيها‬ ‫استعملت‬ ‫دراسة‬ ‫هناك‬ ‫معالجة‬ ‫في‬ ‫األراك‬ ‫جذور‬ ‫خالصة‬ ‫الطفيليات‬ ‫بعض‬.. Saudi Journal of Biological Sciences September 2019
  • 42. Miswak serves as a natural toothpaste with antibacterial, anti-caries, anti-periopathic disinfectant having anti-plaque and anti-fungal properties. Miswak sticks are being used by majority of people who cannot afford to buy the commercial western toothbrush and toothpaste mainly in rural areas of developing countries. ‫يعمل‬‫أسنان‬ ‫كمعجون‬ ‫المسواك‬ ‫كم‬ ‫إضافية‬ ‫بخصائص‬ ‫طبيعي‬‫ضاد‬ ‫األسنان‬ ‫لنخر‬ ‫ومضاد‬ ‫للجراثيم‬ ‫للفطور‬ ‫ومضاد‬ ‫األسنان‬ ‫ولقلح‬.. ‫قبل‬ ‫من‬ ‫المسواك‬ ‫ويستخدم‬ ‫يستطيعو‬ ‫ل‬ ‫الذين‬ ‫الكثيرين‬‫ن‬ ‫ومعاجين‬ ‫األسنان‬ ‫فراشي‬ ‫شراء‬ ‫األسنان‬..‫الناطق‬ ‫في‬ ‫وخاصة‬ ‫النامية‬ ‫البلدان‬ ‫في‬ ‫النائية‬..
  • 43. ‫أنه‬ ‫الدراسات‬ ‫هذه‬ ‫من‬ ‫يتضح‬ ‫يمكن‬‫نب‬ ‫األراك‬ ‫اعتبارشجرة‬‫ا‬‫ا‬‫ات‬ ‫م‬ ‫ا‬‫ال‬‫كام‬ ‫ا‬‫ا‬‫درع‬ ‫يمتلك‬ ‫ا‬‫ا‬‫طبي‬‫ن‬ ‫الفعالة‬ ‫المركبات‬..‫والخصائ‬‫ص‬ ‫الدوائية‬..‫الحد‬ ‫والتطبيقات‬‫يثة‬.. ‫الناش‬ ‫المختلفة‬ ‫المجالت‬ ‫في‬‫ئة‬. Journal of Ethnopharmacology 213 (2018) 409–444 It is obvious from this review that S. persica can be regarded as an important traditionally used medicinal plant harboring a panoply of bioactive compounds, pharmacological properties, and modern applications in emerging fields of interest.
  • 44. Conclusion: S. persica showed a wide scope of application and its uses extended far beyond the initial traditional uses of its roots, stems, & twigs in oral care. Other ethnopharmacological uses and potential applications of different parts of S. persica warrants further investigations. ‫الخالصة‬: ‫تطبيقا‬ ‫األراك‬ ‫لشجرة‬ ‫أن‬ ‫لشك‬‫ت‬ ‫عديدة‬..‫وأن‬‫تجاوزت‬ ‫استعمالتها‬ ‫التقليدي‬ ‫اإلستعمالت‬ ‫بكثير‬‫ة‬ ‫المعروفة‬‫األراك‬ ‫شجرة‬ ‫لجذور‬.. ‫وجذوعها‬..‫وأغصانها‬..‫في‬ ‫وذلك‬ ‫الفم‬ ‫بصحة‬ ‫العناية‬. ‫من‬ ‫العديد‬ ‫وهناك‬‫اإلستعمالت‬ ‫شجرة‬ ‫أجزاء‬ ‫لمختلف‬ ‫المحتملة‬ ‫األراك‬..‫من‬ ‫المزيد‬ ‫إلى‬ ‫وتحتاج‬ ‫األبحاث‬ Journal of Ethnopharmacology 2018,213: 409–444
  • 46. ‫السواك‬ ‫تأكد‬ ‫أوقات‬ 1-‫الوضوء‬ ‫عند‬.‫وس‬ ‫عليه‬ ‫هللا‬ ‫صلى‬ ‫النبي‬ ‫عن‬ ‫عنه‬ ‫هللا‬ ‫رضى‬ ‫هريرة‬ ‫أبي‬ ‫لحديث‬‫قال‬ ‫لم‬: (‫وضوء‬ ‫كل‬ ‫عند‬ ‫بالسواك‬ ‫ألمرتهم‬ ‫أمتي‬ ‫على‬ ‫أشق‬ ‫أن‬ ‫لول‬)‫البخاري‬ ‫رواه‬. 2-‫للصالة‬ ‫القيام‬ ‫عند‬.‫هللا‬ ‫صلى‬ ‫هللا‬ ‫رسول‬ ‫أن‬ ‫عنه‬ ‫هللا‬ ‫رضى‬ ‫هريرة‬ ‫أبي‬ ‫لحديث‬‫عليه‬ ‫قال‬ ‫وسلم‬( :‫صالة‬ ‫كل‬ ‫مع‬ ‫بالسواك‬ ‫ألمرتهم‬ ‫الناس‬ ‫على‬ ‫أو‬ ‫أمتي‬ ‫على‬ ‫أشق‬ ‫أن‬ ‫لول‬)‫الب‬‫خاري‬ 3-‫النوم‬ ‫من‬ ‫القيام‬ ‫عند‬.‫قال‬ ‫عنه‬ ‫هللا‬ ‫رضى‬ ‫حذيفة‬ ‫لحديث‬( :‫هللا‬ ‫صلى‬ ‫النبي‬ ‫كان‬‫عليه‬ ‫بالسواك‬ ‫فاه‬ ‫يشوص‬ ‫الليل‬ ‫من‬ ‫قام‬ ‫إذا‬ ‫وسلم‬)‫البخاري‬ ‫رواه‬. 4-‫المنزل‬ ‫دخول‬ ‫عند‬.‫عنها‬ ‫هللا‬ ‫رضي‬ ‫عائشة‬ ‫لحديث‬(‫وس‬ ‫عليه‬ ‫هللا‬ ‫صلى‬ ‫النبي‬ ‫أن‬‫كان‬ ‫لم‬ ‫بالسواك‬ ‫بدأ‬ ‫بيته‬ ‫دخل‬ ‫إذا‬)‫مسلم‬ ‫رواه‬ 5-‫األسنان‬ ‫واصفرار‬ ‫الفم‬ ‫تغير‬ ‫عند‬.‫عنها‬ ‫هللا‬ ‫رضي‬ ‫عائشة‬ ‫لحديث‬(‫ص‬ ‫النبي‬ ‫أن‬‫هللا‬ ‫لى‬ ‫قال‬ ‫وسلم‬ ‫عليه‬:‫للرب‬ ‫مرضاة‬ ‫للفم‬ ‫مطهرة‬ ‫السواك‬)‫البخاري‬ ‫رواه‬. 6-‫الكريم‬ ‫القرآن‬ ‫قراءة‬ ‫عند‬:‫وسلم‬ ‫عليه‬ ‫هللا‬ ‫صلى‬ ‫قال‬( :‫ثم‬ ‫تسوك‬ ‫إذا‬ ‫العبد‬ ‫إن‬‫قام‬ ‫منه‬ ‫فيدنو‬ ‫قراءته‬ ‫إلى‬ ‫فيستمع‬ ‫خلفه‬ ‫الملك‬ ‫قام‬ ‫يصلي‬-‫نحوها‬ ‫كلمة‬ ‫أو‬-‫ي‬ ‫حتى‬‫فاه‬ ‫ضع‬ ‫أفواهك‬ ‫فطهروا‬ ‫الملك‬ ‫جوف‬ ‫في‬ ‫صار‬ ‫إل‬ ‫القرآن‬ ‫من‬ ‫شىء‬ ‫فيه‬ ‫من‬ ‫يخرج‬ ‫فما‬ ‫فيه‬ ‫على‬‫م‬ ‫للقرآن‬)‫البيهقي‬ ‫رواه‬.‫ثقات‬ ‫رجاله‬ ‫البزار‬ ‫وقال‬.
  • 47.
  • 48.
  • 49. •‫هللا‬ ‫رضي‬ ‫الزهراء‬ ‫فاطمة‬ ‫زوجته‬ ‫على‬ ‫طالب‬ ‫أبي‬ ‫بن‬ ُّ‫ي‬‫عل‬ ‫دخل‬ ‫عنهما‬..‫أراك‬ ْ‫من‬ ٍ‫بسواك‬ ‫تستاك‬ ‫فرآها‬..‫بي‬ ‫في‬ ‫لها‬ ‫فقال‬‫تين‬ ‫عجيبين‬ ‫جميلين‬: ‫بثغرها‬ ِ‫األراك‬ َ‫د‬‫عو‬ ‫يا‬ َ‫حظيت‬...‫األ‬ َ‫د‬‫عو‬ ‫يا‬ َ‫ت‬ْ‫ف‬‫خ‬ ‫أما‬َ‫أراك‬ ِ‫راك‬ َ‫ك‬ُ‫ت‬ْ‫ل‬‫قت‬ ‫القتال‬ ِ‫ل‬‫أه‬ ْ‫من‬ َ‫كنت‬ ‫لو‬...ِ‫س‬ ‫يا‬ ‫مني‬ َ‫فاز‬ ‫ما‬َ‫واك‬ِ‫س‬ ُ‫واك‬