1) CBCC was founded in 1984 in California as a small cancer clinic and has since expanded to become one of the largest cancer care providers in North America and India, operating multiple centers with over 30 oncologists and providing care and clinical trials to thousands of patients annually. 2) The document provides details on CBCC's centers and operations in the US and India, including locations, services, numbers of patients and clinical trials conducted across various cancer types. 3) CBCC has extensive experience conducting oncology clinical trials, with a focus on trials for breast, lung, ovarian and other cancers, and has participated in trials for many now-approved drugs through their affiliation with UCLA.

1. USA ● INDIA
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2. CBCC Group - Journey at glance
1984 Founded by Dr. Ravi Patel with small cancer clinic of 12,000 Sq. ft.
1990 Expanded into a larger facility with several stations
Began to participate in oncology clinical trials with affiliation to UCLA.1995
1996 Renamed clinic to Comprehensive Blood & Cancer Centre (CBCC).
2007  Opened a new 70,000 sq ft cancer centre becoming the largest centre on west coast,USA.
2008 Inaugurated a brand new centre CBCC CyberKnife® Center.
2011  Acquired an HDXT MRI for expanding diagnosis for Breast Cancer.
2015
 Started operation in Gujarat, India.
 Started operation in other Indian states Chaatisgadh, Madhyapradesh and Andhra Pradesh.
Started operation in Tamilnadu, India.
2012 Acquired Vigbyor Research India to manage India Operation.
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3. CBCC Centers in US – Global HQ
Bakersfield, CA Delano, CATempleton, CA
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4. CBCC USA details
www.cbcc.com
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Investigators at CBCC USA
Investigator's Name Specialty
Dr Ravi Patel Medical Oncology
Dr Alan Cartmell Medical Oncology
Dr David Kanamori Medical Oncology
Dr Shawn Shambaugh Medical Oncology
Dr Pradip Rustagi Medical Oncology
Dr Kota Chandra Shekar Medical Oncology
Dr Giridhar Gorla Radiation Oncology
Dr Ajay Desai Radiation Oncology

5. CBCC USA details
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Annual New Consults
Solid Tumors
Breast 354
Prostate 135
Colorectal 113
Lung 110
GYN 96
Gastric 78
Head & Neck 49
Brain 48
Thyroid 34
Bladder 33
Kidney 20
Testicular 20
Liver 15
Skin Cancer
Basal/Squamous 510
Melanoma 21
Hematologic
Anemia 277
Lymphoma 84
Multiple Myeloma 13
Leukemia 17

6. CBCC USA details
www.cbcc.com
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List of Clients:
1. Pfizer
2. Genentech
3. AstraZeneca
4. Lilly
5. Bristol Myers Squib
6. Amgen
7. Bayer
8. ABBVIE
9. Onyx Pharmaceuticals
10. Merck
Studies we have participated that were investigational and now are approved.
 Palbociclib
Crizotinib,
Tarceva,
Avastin,
Neupogen,
Procrit,
Herceptin
Perjeta
Kadecyla
 Aloxi
 Emend
Rituxan

7. UCLA Affiliation
 CBCC is part of the UCLA Jonsson Comprehensive Cancer Center's Translational Oncology Research
International (TORI) network. CBCC has collaborated in over 100 clinical trials with UCLA. This partnership
allows CBCC and other leading research institutions and health care providers to offer clinical and
research trials beyond the UCLA campus. All types of cancers are included in these important studies.
 What this means to our patients is that they have early access to the latest clinical trials without having to
travel. For a comprehensive list of all our active clinical trials please click here.
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8. CBCC Hospitals in India
Raipur - Chattisgarh
Indore - Madhyapradesh
Ahmedabad - Gujarat
Trichy - Tamilnadu
Chennai - Tamilnadu
Jadcherla – Andhra Pradesh
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9. 13/Jan/2016CBCC-VIBGYOR_List of Oncology Sites
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Apollo CBCC Center Ahmedabad Vamshi CBCC Cancer & General
Hospital, Jadcherla
G Vishwanathan CBCC Cancer
Hospital, Trichy
Dr. Rai CBCC Cancer Center,
Chennai
Sanjeevani CBCC Cancer Hospital,
Raipur
CHL CBCC Cancer Hospital, Indore
CBCC Hospitals in India

10. Infrastructure Details – Site wise/India
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Center Bed
Strength
No of
Consultants
Core Department Radiology Pathology
Ahmedabad 93 31 Surgical, Medical, Radiation, Hemato
Oncology and Stem Cell Transplant
In House In House
Raipur 70 7 Surgical, Medical, Radiation & Hemato
Oncology
In House In House
Indore 60 8 Surgical, Medical, Radiation & Hemato
Oncology
In House In House
Chennai 50 6 Surgical, Medical, Radiation & Hemato
Oncology
In House Outsourced
Trichy 50 7 Surgical, Medical, Radiation & Hemato
Oncology
In House In House
Jadcherla 70 6 Surgical, Medical, & Hemato Oncology Outsourced Outsourced

11. Annual patient turnover at each site/India
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Center Surgery Chemo Radiation Total
Ahmedabad 800 4,200 780 5,780
Raipur 480 1,440 480 2,400
Indore 840 2,400 840 4,080
Chennai 600 1,440 600 2,640
Trichy 360 1,080 600 2,040
Jadcherla 450 1200 100 1750

12. Services
 Clinical Trial Project Management of Phase II-IV
 PK end point studies on patients
 Clinical monitoring
 Clinical Data Management
 Medical Writing and Communication
 Pharmacovigilence
 Post market Trials of Drugs and Devices
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13. Oncology Clinical Trial
Capability/Experience
 Breast Cancer
 Head and Neck Cancer
 Lung Cancer
 Ovarian Cancer
 Pancreatic Cancer
 Prostate Cancer
 Colon Cancer
 Esophageal/Gastric Cancer
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14. Experience of PK end point studies
 PK End point study of liposomal doxorubicin on ovarian Cancer patients: 46 patients enrolled at
12 sites.
 PK End point study of liposomal doxorubicin on ovarian Cancer patients: 30 patients enrolled at
08 sites.
 PK End point study of Capecitabin on Metastatic Brest Cancer patients: 54 patients enrolled at 10
sites.
 PK End point study of Capecitabin on Metastatic Brest Cancer patients: 46 patients enrolled at 08
sites.
 PK End point study of Sunitinib on advanced renal cell carcinoma patients: 60 patients enrolled at
10 sites.
 PK End point study of Bortezomib on multiple myeloma patients: 30 patients enrolled at 07 sites.
 PK End point study of Imatinib on CML patients: 36 patients enrolled at 06 sites.
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15. Why CBCC for PK end point studies
 With extensive setup in India and USA, we recruit patients at our own hospital site and not
dependent on the outside investigator sites for the enrolment.
 Common SOP and training system at all our hospital sites in India and USA.
 Well equipped sites with infrastructure like Continuous ECG monitoring, Automated
centrifuge , Deep freezer, Pharmacy freezers.
 Strong documentation system at all sites to archive study documents which is essential for
regulatory audits at site.
 Well trained site staff having experience of managing international regulatory audits.
 While recruiting patients for one indication we don’t accept another study with same
indication to complete the total recruitment in the shortest possible time.
 CTMS softer with unique sponsor login to present continuous study updates to Sponsor
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16. Key Differentiator
 More than 30 years of rich experience in Clinical trials with core focus on Oncology.
 Largest private Cancer Care Provider in North America.
 Global outreach to manage complex clinical trials in various locations.
 Rich experience of successful trial execution and submission to various regulatory agencies
around the globe.
 Very stable top management.
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17. THANK YOU
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