Originally, MR1 was described in the presentation of bacteria antigens to mucosal-associated invariant T (MAIT) cells. MR1 is a ubiquitously expressed non-polymorphic MHC class I-like molecule that is conserved across species and human. MR1 can form tetramer complexes with β2-microglobulin (β2M), which is an 11.8-kD protein interacting and stabilizing MR1.https://www.creativebiolabs.net/mr1-tetramer_17.htm