Pre-emptive Transplantation Why Bother?
Patient Survival is Improved - USRDS
Graft Survival is improved - USRDS
Avoid Dialysis Related Morbidity <ul><li>USRDS – 20% patients on dialysis are hospitalised per year for access problems </...
Transplants Don’t Happen Too Early <ul><li>4095 Pre-emptive transplants analysed in US between 1994 – 2000. </li></ul><ul>...
Transplants Ultimately Cost Less <ul><li>£17500 year for pd </li></ul><ul><li>£35000 year for Hospital HD </li></ul><ul><l...
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Pre Emptive Transplantation

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Pre Emptive Transplantation

  1. 1. Pre-emptive Transplantation Why Bother?
  2. 2. Patient Survival is Improved - USRDS
  3. 3. Graft Survival is improved - USRDS
  4. 4. Avoid Dialysis Related Morbidity <ul><li>USRDS – 20% patients on dialysis are hospitalised per year for access problems </li></ul><ul><li>>50% of these are related to infection </li></ul><ul><li>Transplant patients average 0.79 admissions/year vs 1.94 (haemo) & 1.98 (PD) </li></ul>
  5. 5. Transplants Don’t Happen Too Early <ul><li>4095 Pre-emptive transplants analysed in US between 1994 – 2000. </li></ul><ul><li>eGFR averaged 9.9 ml/min (SD 5.3) at time of transplantation </li></ul><ul><li>Ishani A, et al. Impact of pre-transplant eGFR on the outcome of living donor pre-emptive renal transplantation. www.usrds.org, 2002 . </li></ul>
  6. 6. Transplants Ultimately Cost Less <ul><li>£17500 year for pd </li></ul><ul><li>£35000 year for Hospital HD </li></ul><ul><li>£17000 per transplant including induction but not UK transplant costs. </li></ul><ul><li>£5000 year for immunosuppression </li></ul><ul><li>£24100 / year of functioning transplant saved. </li></ul>

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