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- 1. CASE STUDY PRESENTATION B.Nagendra prasad Pharm.D Post Baccalaureate
- 2. PEMPHIGUS VULGARIS It is a chronic blistering skin disease with skin lesions that are rarely pruritus , but which are often painful. PAHOPHYSIOLOGY It is autoimmune disease
- 3. IMAGES
- 4. PATIENT PROFILE NAMEX :XXXX Age:19 Sex:Male Dept:D.V.L DOA: 09/3/13 C/O: H/O Fluid dilled lesions all over the body including scalp,oralcavity. And genitalia since 2months
- 5. HISTORY OF ILLNESS Patient initially developed blisters over face, back and erosions over oral cavity. PREVIOUS ILLNESS Patient had oral lesion 6months FAMILY HISTORY Conjunctiva muscles redness + Conjunctivitis
- 6. CUTANEOUS EXAMINATION Flaccid blister were prevent over trunk, lower limbs and back Crusted plagues over the face, front of chest , over right thigh & right hand scalp. Superficial erosion are sheltered are both four arms ,face, back Ulcer with unsheathing granulation tissue of around 6×5cm area right prevent.
- 7. Genital mucosa , erosions were present conjunctivitis, prevent. Oral mucosa super facial erosions are prevent Nikolskys sign –positive. DIAGNOSIS Pemphigus vulgar is
- 8. PHARMCOTHERAPY SNO DRUDS DOSE FREQ UANC E DAY 1 DAY 2 DAY 3 DAY 4 DAY 5 DAY 6 1 INJ. CEFTRI AXONE. IV 1gm yes yes yes yes yes yes 2 INJ. Decadro n.iv od yes yes yes yes yes yes 3 Saline 4 Kmno4 bath yes yes yes yes yes yes 5 Candid mouth wash yes yes yes yes yes yes
- 9. 6 REXIDI NE MO yes yes yes yes 7 T. PANTO P OD yes yes yes yes 8 T.BC OD yes yes yes yes 9 T. CA BIS yes yes yes yes 10 SOFRA MYCIN yes yes yes yes
- 10. T. FLUC ONAZ OL 200mg od yes yes yes NO NO T.Augu mentin 625mg od NO NO yes yes yes T. PCT 500mg od NO NO yes yes yes
- 11. PATIENT COUNCELLING Regarding Disease Regarding Drugs Regarding Lifestyle Modification Drug - drug interaction Adverse drug reaction
- 12. DRUG INTERACTIONS Fluconzole may increase the blood levels and effects of dexametasone.
- 13. ADVERS DRUG REACTION AUGUMENTIN headache,nausea,dizziness, vomting, diarrhoea ,GI discomfort, hemolytic anemia , urticaria, DECADRON growth retardation , peptic ulcer, local irritation .
- 14. REGARDING LIFE STYLE MODIFICATION Take regular modification To avoid allergic food
- 15. S