SlideShare a Scribd company logo
1 of 5
Download to read offline
Maintaining healthy cholesterol levels with
red rice yeast
Many elderly patients, particularly in our Abbotts of Leigh clinic, ask if there are
alternatives to statin drugs to lower high cholesterol.
What is cholesterol?
Cholesterol is made by the liver, but also found in fatty foods. There are two types of
cholesterol: HDL or "good" cholesterol (high-density lipoproteins) and LDL or "bad"
cholesterol (low-density lipoproteins (or LDL). If LDL cholesterol is high it gets deposited
on the walls of your arteries, forming a plaque that clogs your blood vessels and stops
your blood flowing properly. Eventually the plaque hardens your arteries, a condition
called atherosclerosis. HDL cholesterol removes LDL cholesterol from the arteries and the
body, via the liver.
It is important to keep LDL cholesterol levels low as high levels can make you more likely
to have a heart attack or a stroke. So statin drugs have an important role to play.
Unfortunately statin drugs are well known for their side effects and many people find
that the side effects of the drugs outweigh their benefits.
Statin drug side effects
Common statin side effects include:
 Headaches
 Difficulty sleeping
 Skin flushes
 Muscle pain, aches, tenderness, or weakness (myalgia)
 Drowsiness
 Dizziness
 Nausea or vomiting
 Stomach cramps or pain
 Bloating or gas
 Diarrhoea
 Constipation
 Rashes
Some statins also carry warnings that memory loss, mental confusion, high blood sugar,
and type 2 diabetes are possible side effects.
Although patient information leaflets say that statins are well tolerated by most people,
we know that most people do not report side effects. In addition, the symptoms of
muscle aches and pains are often put down to arthritis, or even sometimes dismissed as
"at your age a few aches and pains are to be expected"! Equally, giddiness and dizziness
are sometimes put down to "standing up too quickly".
If you do have a test which shows you have high LDL cholesterol levels, but your GP or
Medical Herbalist does not believe you are in immediate danger, there are several things
you can try before starting statin drugs.
Reduce your cholesterol intake
You can immediately improve your diet and cut down on foods that are high in
cholesterol, saturated fat, and trans fats. Use olive oil instead of butter or blocks of
margarine. Yoghurt instead of cream. Steam or grill instead of frying. Use low fat milk
and cheeses. Try fish and tofu instead of red meat. Avoid fried and fatty foods like chips,
bacon, burgers and commercial cakes and biscuits made of hydrogenated fats. Avoid
crisps and nuts if you're snacking and replace them with dried fruit or pretzels. Eat more
fruit and vegetables, especially raw.
In addition to this, it is worth taking a food supplement called red rice yeast. It comes in
capsules and is taken daily.
If you have tested for high LDL levels, take red rice yeast capsules daily and ask to be
retested every month for three months to see if your body can correct itself. Avoiding
statin drugs and their well known side effects by improving your diet with this
supplement will help to preserve your overall health for longer. If you are having other
related problems or can't get to grips with your diet, book an appointment with a
medical herbalist.
What is red rice yeast?
Red rice yeast (Monascus purpureus) is a food supplement made of a red coloured yeast
grown on rice, that is used extensively in Chinese cooking to make such classics as
Peking Duck and Char Siu. That is where they get their characteristic red colour from.
Red rice yeast contains many natural compounds including a group of fourteen
monacolins. One of them, monacolin K, is what the statin drug lovastatin is made from.
These monacolins work in similar way to statin drugs and lower cholesterol levels.
However, perhaps as they are not so concentrated, or perhaps because other compounds
provide a protective effect, red rice yeast does not seem to cause the same level of side
effects as statin drugs ( Becker et al, 2009).
Red rice yeast does not cause the same side effects but is still efficacious in lowering
harmful LDL cholesterol (Feuerstein & Bjerke, 2012). Where clinical trials have
demonstrated side effects from red rice yeast, for example, similar levels of muscles
weakness to pravastatin, the dose of red rice yeast has been surprisingly high
- 2400 mg x 2 times a day - a total of 4800 mg ( Halbert et al, 2010).
How much should I take?
An overview of multiple studies by Katan et al, 2003, showed that doses above 2000 mg
total per day are unnecessary. They also showed that plant sterols and stanols work best
when combined with an unsaturated fat diet.
Try taking 400 mg capsules 3 times a day (a total of 1200 mg), in combination with an
improved diet, to help your LDL levels return to normal without experiencing side effects.
If they are very high you could take 5 capsules a day (5 x 400 mg = 2000 mg) for the
first week or two, but then lower the amount again, especially if you have been
intolerant to statins previously.
If you are already on statins, you can decrease the statin dose while increasing the red
rice yeast dose, but this should be done under the supervision of your medical herbalist
or GP with access to frequent testing. It is best, if possible, to try red rice yeast first
before commencing statin therapy.
Choosing the right red rice yeast
It is possible to buy red rice yeast on its own. This is the cheapest way but there are
some things to take into consideration. Red rice yeast capsules made in the USA does
not contain monacolin K. This is because the FDA regulations require it to be removed to
avoid people who are taking it with statin drugs receiving too high a level. So it is
'weaker' than red rice yeast produced in the European Union where this is not required.
Red rice yeast is often sold in combination with the natural enzyme CoQ10 (ubiquinone)
which is found in every cell of the body. Low levels of CoQ10 are particularly associated
with heart failure, Parkinson's disease and gum disease. Statin drugs can reduce
coenzyme Q10 levels by up to 40% (Ghirlanda et al, 1993). Some studies have also
found, although results are mixed, that CoQ10 supplementation helps to reduce the
muscle weakness commonly experienced as a side effect of statin therapy ( Caso et al,
2007).
CoQ10 also has other benefits as well as supporting heart health. It can increase energy.
The heart, liver and kidneys which have the highest energy requirements also naturally
have the highest CoQ10 levels in the body. It also boosts antioxidant levels. Antioxidants
are found in berries, grape seeds and Vitamin E. They help to fight free radicals which
are a primary trigger in cell ageing.
Although it is more expensive, it is a sensible precaution to buy a red rice yeast capsule
with CoQ10 included, especially if you are taking high doses of red rice yeast or are still
taking some statin drugs under the supervision of your medical herbalist or healthcare
practitioner.
What are good cholesterol levels with red rice yeast

More Related Content

Recently uploaded

Call Girls Service Faridabad 📲 9999965857 ヅ10k NiGhT Call Girls In Faridabad
Call Girls Service Faridabad 📲 9999965857 ヅ10k NiGhT Call Girls In FaridabadCall Girls Service Faridabad 📲 9999965857 ヅ10k NiGhT Call Girls In Faridabad
Call Girls Service Faridabad 📲 9999965857 ヅ10k NiGhT Call Girls In Faridabad
gragmanisha42
 
Tirupati Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Tirupati Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetTirupati Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Tirupati Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Call Girls Service
 
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meetnagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Call Girls Service
 
VIP Call Girls Noida Jhanvi 9711199171 Best VIP Call Girls Near Me
VIP Call Girls Noida Jhanvi 9711199171 Best VIP Call Girls Near MeVIP Call Girls Noida Jhanvi 9711199171 Best VIP Call Girls Near Me
VIP Call Girls Noida Jhanvi 9711199171 Best VIP Call Girls Near Me
mriyagarg453
 
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
Sheetaleventcompany
 
Hubli Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Hubli Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetHubli Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Hubli Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Call Girls Service
 
Nanded Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Nanded Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetNanded Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Nanded Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Call Girls Service
 
VIP Call Girl DLF Phase 2 Gurgaon (Noida) Just Meet Me@ 9711199012
VIP Call Girl DLF Phase 2 Gurgaon (Noida) Just Meet Me@ 9711199012VIP Call Girl DLF Phase 2 Gurgaon (Noida) Just Meet Me@ 9711199012
VIP Call Girl DLF Phase 2 Gurgaon (Noida) Just Meet Me@ 9711199012
adityaroy0215
 
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real MeetChandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
priyashah722354
 
Call Girls Chandigarh 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Call Girls Chandigarh 👙 7001035870 👙 Genuine WhatsApp Number for Real MeetCall Girls Chandigarh 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Call Girls Chandigarh 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
priyashah722354
 
9316020077📞Goa Call Girls Numbers, Call Girls Whatsapp Numbers Goa
9316020077📞Goa  Call Girls  Numbers, Call Girls  Whatsapp Numbers Goa9316020077📞Goa  Call Girls  Numbers, Call Girls  Whatsapp Numbers Goa
9316020077📞Goa Call Girls Numbers, Call Girls Whatsapp Numbers Goa
russian goa call girl and escorts service
 
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in ChandigarhChandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
Sheetaleventcompany
 
Russian Call Girls in Noida Pallavi 9711199171 High Class Call Girl Near Me
Russian Call Girls in Noida Pallavi 9711199171 High Class Call Girl Near MeRussian Call Girls in Noida Pallavi 9711199171 High Class Call Girl Near Me
Russian Call Girls in Noida Pallavi 9711199171 High Class Call Girl Near Me
mriyagarg453
 

Recently uploaded (20)

Call Girls Service Faridabad 📲 9999965857 ヅ10k NiGhT Call Girls In Faridabad
Call Girls Service Faridabad 📲 9999965857 ヅ10k NiGhT Call Girls In FaridabadCall Girls Service Faridabad 📲 9999965857 ヅ10k NiGhT Call Girls In Faridabad
Call Girls Service Faridabad 📲 9999965857 ヅ10k NiGhT Call Girls In Faridabad
 
Tirupati Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Tirupati Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetTirupati Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Tirupati Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
 
(Ajay) Call Girls in Dehradun- 8854095900 Escorts Service 50% Off with Cash O...
(Ajay) Call Girls in Dehradun- 8854095900 Escorts Service 50% Off with Cash O...(Ajay) Call Girls in Dehradun- 8854095900 Escorts Service 50% Off with Cash O...
(Ajay) Call Girls in Dehradun- 8854095900 Escorts Service 50% Off with Cash O...
 
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meetnagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
nagpur Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
 
VIP Call Girls Noida Jhanvi 9711199171 Best VIP Call Girls Near Me
VIP Call Girls Noida Jhanvi 9711199171 Best VIP Call Girls Near MeVIP Call Girls Noida Jhanvi 9711199171 Best VIP Call Girls Near Me
VIP Call Girls Noida Jhanvi 9711199171 Best VIP Call Girls Near Me
 
❤️♀️@ Jaipur Call Girl Agency ❤️♀️@ Manjeet Russian Call Girls Service in Jai...
❤️♀️@ Jaipur Call Girl Agency ❤️♀️@ Manjeet Russian Call Girls Service in Jai...❤️♀️@ Jaipur Call Girl Agency ❤️♀️@ Manjeet Russian Call Girls Service in Jai...
❤️♀️@ Jaipur Call Girl Agency ❤️♀️@ Manjeet Russian Call Girls Service in Jai...
 
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
Call Girl In Zirakpur ❤️♀️@ 9988299661 Zirakpur Call Girls Near Me ❤️♀️@ Sexy...
 
Call Girls Hyderabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Hyderabad Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Hyderabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Hyderabad Just Call 9907093804 Top Class Call Girl Service Available
 
(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...
(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...
(Deeksha) 💓 9920725232 💓High Profile Call Girls Navi Mumbai You Can Get The S...
 
Hubli Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Hubli Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetHubli Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Hubli Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
 
Nanded Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Nanded Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real MeetNanded Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
Nanded Call Girls 👙 6297143586 👙 Genuine WhatsApp Number for Real Meet
 
Call Girl Raipur 📲 9999965857 whatsapp live cam sex service available
Call Girl Raipur 📲 9999965857 whatsapp live cam sex service availableCall Girl Raipur 📲 9999965857 whatsapp live cam sex service available
Call Girl Raipur 📲 9999965857 whatsapp live cam sex service available
 
VIP Call Girl DLF Phase 2 Gurgaon (Noida) Just Meet Me@ 9711199012
VIP Call Girl DLF Phase 2 Gurgaon (Noida) Just Meet Me@ 9711199012VIP Call Girl DLF Phase 2 Gurgaon (Noida) Just Meet Me@ 9711199012
VIP Call Girl DLF Phase 2 Gurgaon (Noida) Just Meet Me@ 9711199012
 
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real MeetChandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Chandigarh Call Girls 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
 
❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF ...
❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF  ...❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF  ...
❤️♀️@ Jaipur Call Girls ❤️♀️@ Jaispreet Call Girl Services in Jaipur QRYPCF ...
 
Call Girl Raipur 📲 9999965857 ヅ10k NiGhT Call Girls In Raipur
Call Girl Raipur 📲 9999965857 ヅ10k NiGhT Call Girls In RaipurCall Girl Raipur 📲 9999965857 ヅ10k NiGhT Call Girls In Raipur
Call Girl Raipur 📲 9999965857 ヅ10k NiGhT Call Girls In Raipur
 
Call Girls Chandigarh 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Call Girls Chandigarh 👙 7001035870 👙 Genuine WhatsApp Number for Real MeetCall Girls Chandigarh 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
Call Girls Chandigarh 👙 7001035870 👙 Genuine WhatsApp Number for Real Meet
 
9316020077📞Goa Call Girls Numbers, Call Girls Whatsapp Numbers Goa
9316020077📞Goa  Call Girls  Numbers, Call Girls  Whatsapp Numbers Goa9316020077📞Goa  Call Girls  Numbers, Call Girls  Whatsapp Numbers Goa
9316020077📞Goa Call Girls Numbers, Call Girls Whatsapp Numbers Goa
 
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in ChandigarhChandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
Chandigarh Escorts, 😋9988299661 😋50% off at Escort Service in Chandigarh
 
Russian Call Girls in Noida Pallavi 9711199171 High Class Call Girl Near Me
Russian Call Girls in Noida Pallavi 9711199171 High Class Call Girl Near MeRussian Call Girls in Noida Pallavi 9711199171 High Class Call Girl Near Me
Russian Call Girls in Noida Pallavi 9711199171 High Class Call Girl Near Me
 

Featured

How Race, Age and Gender Shape Attitudes Towards Mental Health
How Race, Age and Gender Shape Attitudes Towards Mental HealthHow Race, Age and Gender Shape Attitudes Towards Mental Health
How Race, Age and Gender Shape Attitudes Towards Mental Health
ThinkNow
 
Social Media Marketing Trends 2024 // The Global Indie Insights
Social Media Marketing Trends 2024 // The Global Indie InsightsSocial Media Marketing Trends 2024 // The Global Indie Insights
Social Media Marketing Trends 2024 // The Global Indie Insights
Kurio // The Social Media Age(ncy)
 

Featured (20)

Product Design Trends in 2024 | Teenage Engineerings
Product Design Trends in 2024 | Teenage EngineeringsProduct Design Trends in 2024 | Teenage Engineerings
Product Design Trends in 2024 | Teenage Engineerings
 
How Race, Age and Gender Shape Attitudes Towards Mental Health
How Race, Age and Gender Shape Attitudes Towards Mental HealthHow Race, Age and Gender Shape Attitudes Towards Mental Health
How Race, Age and Gender Shape Attitudes Towards Mental Health
 
AI Trends in Creative Operations 2024 by Artwork Flow.pdf
AI Trends in Creative Operations 2024 by Artwork Flow.pdfAI Trends in Creative Operations 2024 by Artwork Flow.pdf
AI Trends in Creative Operations 2024 by Artwork Flow.pdf
 
Skeleton Culture Code
Skeleton Culture CodeSkeleton Culture Code
Skeleton Culture Code
 
PEPSICO Presentation to CAGNY Conference Feb 2024
PEPSICO Presentation to CAGNY Conference Feb 2024PEPSICO Presentation to CAGNY Conference Feb 2024
PEPSICO Presentation to CAGNY Conference Feb 2024
 
Content Methodology: A Best Practices Report (Webinar)
Content Methodology: A Best Practices Report (Webinar)Content Methodology: A Best Practices Report (Webinar)
Content Methodology: A Best Practices Report (Webinar)
 
How to Prepare For a Successful Job Search for 2024
How to Prepare For a Successful Job Search for 2024How to Prepare For a Successful Job Search for 2024
How to Prepare For a Successful Job Search for 2024
 
Social Media Marketing Trends 2024 // The Global Indie Insights
Social Media Marketing Trends 2024 // The Global Indie InsightsSocial Media Marketing Trends 2024 // The Global Indie Insights
Social Media Marketing Trends 2024 // The Global Indie Insights
 
Trends In Paid Search: Navigating The Digital Landscape In 2024
Trends In Paid Search: Navigating The Digital Landscape In 2024Trends In Paid Search: Navigating The Digital Landscape In 2024
Trends In Paid Search: Navigating The Digital Landscape In 2024
 
5 Public speaking tips from TED - Visualized summary
5 Public speaking tips from TED - Visualized summary5 Public speaking tips from TED - Visualized summary
5 Public speaking tips from TED - Visualized summary
 
ChatGPT and the Future of Work - Clark Boyd
ChatGPT and the Future of Work - Clark Boyd ChatGPT and the Future of Work - Clark Boyd
ChatGPT and the Future of Work - Clark Boyd
 
Getting into the tech field. what next
Getting into the tech field. what next Getting into the tech field. what next
Getting into the tech field. what next
 
Google's Just Not That Into You: Understanding Core Updates & Search Intent
Google's Just Not That Into You: Understanding Core Updates & Search IntentGoogle's Just Not That Into You: Understanding Core Updates & Search Intent
Google's Just Not That Into You: Understanding Core Updates & Search Intent
 
How to have difficult conversations
How to have difficult conversations How to have difficult conversations
How to have difficult conversations
 
Introduction to Data Science
Introduction to Data ScienceIntroduction to Data Science
Introduction to Data Science
 
Time Management & Productivity - Best Practices
Time Management & Productivity -  Best PracticesTime Management & Productivity -  Best Practices
Time Management & Productivity - Best Practices
 
The six step guide to practical project management
The six step guide to practical project managementThe six step guide to practical project management
The six step guide to practical project management
 
Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...
Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...
Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...
 
Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...
Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...
Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...
 
12 Ways to Increase Your Influence at Work
12 Ways to Increase Your Influence at Work12 Ways to Increase Your Influence at Work
12 Ways to Increase Your Influence at Work
 

What are good cholesterol levels with red rice yeast

  • 1. Maintaining healthy cholesterol levels with red rice yeast Many elderly patients, particularly in our Abbotts of Leigh clinic, ask if there are alternatives to statin drugs to lower high cholesterol. What is cholesterol? Cholesterol is made by the liver, but also found in fatty foods. There are two types of cholesterol: HDL or "good" cholesterol (high-density lipoproteins) and LDL or "bad" cholesterol (low-density lipoproteins (or LDL). If LDL cholesterol is high it gets deposited on the walls of your arteries, forming a plaque that clogs your blood vessels and stops your blood flowing properly. Eventually the plaque hardens your arteries, a condition called atherosclerosis. HDL cholesterol removes LDL cholesterol from the arteries and the body, via the liver. It is important to keep LDL cholesterol levels low as high levels can make you more likely to have a heart attack or a stroke. So statin drugs have an important role to play. Unfortunately statin drugs are well known for their side effects and many people find that the side effects of the drugs outweigh their benefits.
  • 2. Statin drug side effects Common statin side effects include:  Headaches  Difficulty sleeping  Skin flushes  Muscle pain, aches, tenderness, or weakness (myalgia)  Drowsiness  Dizziness  Nausea or vomiting  Stomach cramps or pain  Bloating or gas  Diarrhoea  Constipation  Rashes Some statins also carry warnings that memory loss, mental confusion, high blood sugar, and type 2 diabetes are possible side effects. Although patient information leaflets say that statins are well tolerated by most people, we know that most people do not report side effects. In addition, the symptoms of muscle aches and pains are often put down to arthritis, or even sometimes dismissed as "at your age a few aches and pains are to be expected"! Equally, giddiness and dizziness are sometimes put down to "standing up too quickly". If you do have a test which shows you have high LDL cholesterol levels, but your GP or Medical Herbalist does not believe you are in immediate danger, there are several things you can try before starting statin drugs. Reduce your cholesterol intake You can immediately improve your diet and cut down on foods that are high in cholesterol, saturated fat, and trans fats. Use olive oil instead of butter or blocks of margarine. Yoghurt instead of cream. Steam or grill instead of frying. Use low fat milk and cheeses. Try fish and tofu instead of red meat. Avoid fried and fatty foods like chips, bacon, burgers and commercial cakes and biscuits made of hydrogenated fats. Avoid crisps and nuts if you're snacking and replace them with dried fruit or pretzels. Eat more fruit and vegetables, especially raw.
  • 3. In addition to this, it is worth taking a food supplement called red rice yeast. It comes in capsules and is taken daily. If you have tested for high LDL levels, take red rice yeast capsules daily and ask to be retested every month for three months to see if your body can correct itself. Avoiding statin drugs and their well known side effects by improving your diet with this supplement will help to preserve your overall health for longer. If you are having other related problems or can't get to grips with your diet, book an appointment with a medical herbalist. What is red rice yeast? Red rice yeast (Monascus purpureus) is a food supplement made of a red coloured yeast grown on rice, that is used extensively in Chinese cooking to make such classics as Peking Duck and Char Siu. That is where they get their characteristic red colour from. Red rice yeast contains many natural compounds including a group of fourteen monacolins. One of them, monacolin K, is what the statin drug lovastatin is made from. These monacolins work in similar way to statin drugs and lower cholesterol levels. However, perhaps as they are not so concentrated, or perhaps because other compounds provide a protective effect, red rice yeast does not seem to cause the same level of side effects as statin drugs ( Becker et al, 2009). Red rice yeast does not cause the same side effects but is still efficacious in lowering harmful LDL cholesterol (Feuerstein & Bjerke, 2012). Where clinical trials have demonstrated side effects from red rice yeast, for example, similar levels of muscles weakness to pravastatin, the dose of red rice yeast has been surprisingly high - 2400 mg x 2 times a day - a total of 4800 mg ( Halbert et al, 2010).
  • 4. How much should I take? An overview of multiple studies by Katan et al, 2003, showed that doses above 2000 mg total per day are unnecessary. They also showed that plant sterols and stanols work best when combined with an unsaturated fat diet. Try taking 400 mg capsules 3 times a day (a total of 1200 mg), in combination with an improved diet, to help your LDL levels return to normal without experiencing side effects. If they are very high you could take 5 capsules a day (5 x 400 mg = 2000 mg) for the first week or two, but then lower the amount again, especially if you have been intolerant to statins previously. If you are already on statins, you can decrease the statin dose while increasing the red rice yeast dose, but this should be done under the supervision of your medical herbalist or GP with access to frequent testing. It is best, if possible, to try red rice yeast first before commencing statin therapy. Choosing the right red rice yeast It is possible to buy red rice yeast on its own. This is the cheapest way but there are some things to take into consideration. Red rice yeast capsules made in the USA does not contain monacolin K. This is because the FDA regulations require it to be removed to avoid people who are taking it with statin drugs receiving too high a level. So it is 'weaker' than red rice yeast produced in the European Union where this is not required. Red rice yeast is often sold in combination with the natural enzyme CoQ10 (ubiquinone) which is found in every cell of the body. Low levels of CoQ10 are particularly associated with heart failure, Parkinson's disease and gum disease. Statin drugs can reduce coenzyme Q10 levels by up to 40% (Ghirlanda et al, 1993). Some studies have also found, although results are mixed, that CoQ10 supplementation helps to reduce the muscle weakness commonly experienced as a side effect of statin therapy ( Caso et al, 2007). CoQ10 also has other benefits as well as supporting heart health. It can increase energy. The heart, liver and kidneys which have the highest energy requirements also naturally have the highest CoQ10 levels in the body. It also boosts antioxidant levels. Antioxidants are found in berries, grape seeds and Vitamin E. They help to fight free radicals which are a primary trigger in cell ageing. Although it is more expensive, it is a sensible precaution to buy a red rice yeast capsule with CoQ10 included, especially if you are taking high doses of red rice yeast or are still taking some statin drugs under the supervision of your medical herbalist or healthcare practitioner.