Co-infection of Chronic Lyme DiseaseEhrlichiosis May Bring About CancersCo-infection of Chronic Lyme DiseaseEhrlichiosis M...
With the unending demand for blood in the medical community, it is not surprising thatthe time to test donations/ supplies...
contrasting sharply with the high death rate of patients suffering with the disease whowere already immunocompromised.Emer...
therapies or underlying disease, can compromise recovery and result in more severedisease and oftentimes death.Emerging In...
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Co-infection of Chronic Lyme Disease Ehrlichiosis May Bring About Cancers

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Chronic Lyme disease is a complex multi-system, multi-neuroendocrine, multi-infectious disease that mimics over 360 different inflammatory diseases. Get the best personalized Lyme disease treatment by contacting Envita Medical Centers today.

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Co-infection of Chronic Lyme Disease Ehrlichiosis May Bring About Cancers

  1. 1. Co-infection of Chronic Lyme DiseaseEhrlichiosis May Bring About CancersCo-infection of Chronic Lyme DiseaseEhrlichiosis May Bring About CancersPatients who actually suffer from chronic Ehrlichiosis are often misdiagnosed as havingautoimmune disorders or other chronic disease with similar symptomologies, asEhrlichiosis is generally not tested for. Symptoms typically associated with this infectionare a high fever, headache, chills, as well as muscular aches and pains. These closelymimic those often linked to other tick-borne diseases.Ehrlichiosis EssentialsEhrlichiosis comes in two specific forms including Human Monocytic Ehrlichiosis (HME)and Human Granulocytic Ehrlichiosis (HGE) and commonly originate from the bite ofdifferent ticks. The Lone Star tick (Amblyomma Americanum) bite is a likely carrier ofHME, while HGE has been linked to the bites of both the Deer tick (Ixodes Scapularis)and the Western blacklegged tick (Ixodes Pacificus.) The dog tick (DermacentorVariabilis) is known to transmit both HME and HGE.Ticks that carry Ehrlichiosis are also known to carry and transmit Lyme disease as well.For this reason, patients with Ehrlichiosis should also be tested for Lyme as well.Can Ehrlichiosis be Passed in Blood Transfusion? Yes!
  2. 2. With the unending demand for blood in the medical community, it is not surprising thatthe time to test donations/ supplies for Ehrlichiosis or other tick borne infections ispassed over. Rather the supplies are tested for hepatitis and HIV but beyond that, nomuch else. In parts of the Northeast, it is suspected that Lyme and many of its co-infections are found in great numbers in blood donors and as a result, transfusionsupplies.Ehrlichiosis – The Central Nervous System InvaderIn routine central nervous system (CNS) radiological studies, analyses of cerebrospinalfluid (CSF) samples are seldom pursued. Typically, such tests are prompted only whenprimary care physicians detect specific symptoms or signs that tip the need for moreinformation. In such circumstance when CSF samples were examined (in 15 of 57patients,) 8 of the 15 were found abnormal. The most common abnormalities foundamong the abnormal 15 percent were lymphocytic pleocytosis and elevated proteinlevels.Ehrlichiosis - undetected Infection with ties to CancerThere are four bacteria known to survive and propagate within human neutrophils andtheir bone marrow origins - Ehrlichiosis is one of them.This tick-transmitted rickettsialpathogen, anaplasma phagocytophilum, is a causative agent of human granulocyticanaplasmosis and is found in the direct family line of Ehrlichiosis.About 70 percent of all white blood cells are neutrophils – cells considered to beunsuitable hosts by intracellular bacteria as they are short-lived and serve as primarydefense cells, armed with significant antimicrobial apparatus.A. phagocytophilum infection can alter neutrophil functions and result in clinical disease.Moreover, this infection can inhibit or retard apoptosis, oxidative burst, andphagocytosis, while activating degranulation and cytokine/chemokine production – oftenleading to cancer. At this time it is impossible to say how many infections are cancercausatives, but this one certainly seems to have a link suggesting that leukemia andother lymphatic cancers are catalyzed by epigenetic shifts resultant of Ehrlichiosis.Choi KS, Grab DJ, Dumler JS (2004) Anaplasma phagocytophilum infection induces protracted neutrophildegranulation. Infect Immun 72: 3680–3683.Ehrlichiosis and Immuno-compromised Patients: Recipefor DisasterThe zoonotic illness Ehrlichiosis is caused by Ehrlichia species - bacteria that aredecidedly pleomorphic, intracellular, rickettsia-like organisms.[2-4] Ehrlichia present aclinical spectrum, or symptomology that can vary from a mild, influenza-like illness, to afulminant sepsis syndrome. Typically, we find that Ehrlichiosis is self-limiting and notfatal with death rates in large, unselected series ranging from 1 to 8 percent [3,6-8] -
  3. 3. contrasting sharply with the high death rate of patients suffering with the disease whowere already immunocompromised.Emerging Infectious Diseases. 2002;8(3) © 2002 Centers for Disease Control and Prevention(CDC)The Central Nervous System Invader, EhrlichiosisNeurologic manifestations effect up to 20 percent of Ehrlichiosis patients who can sufferwith a spectrum of symptoms including everything from confusion to frank meningitis. Inone recent case, a patient dealt with persistent obundation and delirium even after feverhas dissipated post-doxycycline administration.Ehrlichia should be considered in the event that headache and confusion come withpancytopenia and transaminase elevation - particularly if the patient has had potentialtick exposures.It should not be surprising that an Ehrlichiosis diagnosis is often because of itsnonspecific clinical and laboratory manifestations. Among patients who were previouslyimmunocompromised, diagnosis can be further delayed because the search foropportunistic infections may further obscure the recognition that Ehrlichia is present.Empiric antimicrobial regimens that are often administered for suspected cryptogenicbacterial and fungal sepsis to immunocompromised subjects rarely include drugseffective against Ehrlichia.Emerging Infectious Diseases. 2002;8(3) © 2002 Centers for Disease Control and Prevention (CDC)Diagnosing EhrlichiosisFor any patient with potential tick exposure in an endemic area who is suffering withfever, transaminase elevations, new-onset thrombocytopenia, or leucopenia, anEhrlichiosis diagnosis should be considered. For those who could be categorized asimmunocompromised, the clinical manifestations are far more severe and can includeneurologic deterioration, multiorgan failure, and even a TTP-like illness. Moreover, thedoxycycline therapy response could be delayed. The use of PCR for confirmatorydiagnosis and early empiric therapy can be life-saving.Emerging Infectious Diseases. 2002;8(3) © 2002 Centers for Disease Control and Prevention (CDC) The Immune System Holds the KeyWithout question, a host’s best defense against rickettsial infection is its cellularimmunity. Ehrlichia clearance from peripheral blood in patients with HGE comes fromelevated levels of interferon gamma. A mouse model of Ehrliciosis showed thatimmunocompromised mice suffer with persistent infection with most eventuallysuccumbing to the disease. Cellular immunity, whether begotten of immunosuppressive
  4. 4. therapies or underlying disease, can compromise recovery and result in more severedisease and oftentimes death.Emerging Infectious Diseases. 2002;8(3) © 2002 Centers for Disease Control and Prevention (CDC)Envita Medical CentersEhrlichia often plays a role in the Lyme disease Complex of infections. In order to dealwith their diagnosis effectively, patients must be shown the scope of their diseaseincluding all present infections, toxins, and heavy metals. When chronic Ehrlichiapresents, treatments for patients must incorporate far higher doses of antibiotics thantypically prescribed; something that Envita takes great care to administer. We invitethose interested in state-of-the-art treatment to contact Envita Medical Centers - a worldleader in Lyme disease treatment.

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