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Canary Foundation Luncheon Presentation
- 1. Welcome Canary Foundation Luncheon Progress to Patients: Canaryโs 10 year journey from tests to clinical trial March 26, 2015
- 5. Strategy
- 6. Strategy โ 10 years later
- 7. # 1 Most cancers take decades to develop
- 8. 1p IT F01 IN d dt q1p = (IN + IT)-q1p x F01 IN + IT (1-e-F01t)q1p = F01 ln(2) t1/2marker qsts= [IN(mass/time) + IT(mass/time)] Steady state can be calculated as: # 2 Cancer generates measurable items in blood
- 9. # 3 But old technology canโt find it until too large
- 10. # 4 New nano-technology can find it 1000 times smaller and 1000 times cheaper!
- 11. # 5 Models show we will save lots of lives
- 12. # 6 Tests will be cost-effective for high-risk patients
- 13. # 7 Finding new blood tests has been elusive
- 14. # 8 Molecular imaging is progressing at a rapid pace
- 15. # 9 Worldโs finest leadership
- 16. # 10 An unprecedented partnership with Stanford
- 17. # 11 And we have inspired global investment CRUK
- 18. # 12 New tests and companies are coming to market
- 19. Cyrcadia health โ Detected Movie Trailer
- 20. Scientific Panel Sanjiv Sam Gambhir, MD, PhD โ Chair, Department of Radiology, Stanford University Jim Brooks, MD - Chief, Urologic Oncology, Stanford University Utkan Demirci, PhD - Associate Professor, Stanford University Heidi Auman, PhD โ Scientific Program Manager, Canary Foundation
- 24. New Ideas Clinical Research $20M COE 7 years $10M Team 10 years $50K Individual 1 year Facilities Faculty Associates Science Technology $50M Center 10 years Science
- 25. New Ideas Clinical Research $20M COE 7 years $10M Team 10 years $50K Individual 1 year Facilities Faculty Associates Science Technology $50M Center 10 years Science Spin-outs Medical device Imaging tech
- 26. New Ideas Clinical Research Clinical Trials $20M COE 7 years $10M Team 10 years $50K Individual 1 year Facilities Faculty Associates Science Technology $50M Center 10 years Science Spin-outs Medical device Imaging tech
- 27. New Ideas Clinical Research Clinical Trials $20M COE 7 years $10M Team 10 years $50K Individual 1 year Facilities Faculty Associates Diagnostic Companies Science Technology $50M Center 10 years Science Spin-outs Medical device Imaging tech Diagnostic test
- 29. Lung Cancer Breast Cancer Molecular Imaging
- 30. Measuring densities of cells in real-time down to a single-cell level
- 31. 31 Lab on a chip
- 32. Development of a Clinical Test Clinical Trials for CT + Biomarkers CT + Biomarker Trial initiated by MD Anderson 10,000 in US & International participation in China, Germany, Brazil Multiple techniques to analyze a common set of samples Integrate data and discover biomarkers Smokers vs. Never Smokers Cell Lines Tumors Blood Pro-Surfactant Protein B (pro-SFTPB) Validation Lung cancer research & clinical trial
- 33. Novel strategy
- 34. Ovarian cancer clinical trial
- 36. PASS Clinical Trial 1,000+ Men 5 Year Follow-upNo Progression Suspected Central Bio-Repository Progression Suspected Option for Treatment Tissue Resources for Validation Tissue of 1,000+ men who have had radical treatment 500+ Non-recurrent cancer 500+ Recurrent cancer 1,000s of prostate cancer tissues arrayed to maximize rapid and efficient analysis Prostate cancer clinical trial
- 39. Pancreas microbubble in mice
- 42. Motivation for TRUSPA Imaging of Prostate TRUS guided prostate biopsy Sagittal Ultrasound Transverse Ultrasound
- 45. 45 Pilot Clinical Trial: TRUSPA Imaging of Prostate Prostate Capsule
- 47. Clinical Trials Prostate Ovary Pancreas $1,500 to sponsor 1 person $3,000 to sponsor 2 people $4,500 to sponsor 3 people
- 49. Thank You Canary Luncheon Committee Dear Pixels Lobird Laure Woods Avaya Union Bank Village Doctors William K Bowes Jr. Foundation Franklin and Cathryn Johnson Family Foundation Debbi Spungen in memory of Florence Spungen
- 50. Canary Challenge
- 51. Canary Challenge โ September 26, 2015