This study examined the prevalence of microalbuminuria (MAU) in 128 patients with hypertension and its correlation with target organ damage. The results showed that MAU was present in 37.5% of hypertensive patients overall and was more prevalent in older patients and those with longer disease duration. MAU had a positive correlation with duration and severity of hypertension, male sex, obesity, low HDL levels, high LDL levels, and evidence of retinopathy or left ventricular hypertrophy on ECG. The study concludes that MAU is an important early marker of target organ damage in hypertension.

2. Microalbuminuria: an integrated marker of target organ damage.

3. Regression of left ventricular hypertrophy†: Parallels ↓ in MAU regardless of BP changes.

4. AIMS:

5. Prevalence of MAU in Htn.

9. 128 cases of hypertension : JNC 7 criteria

10. Duration: 1 year from July 2007 to June 2008

11. Examined clinically,RoutineInv,CrCl. Lipids ophthalmoscopy, ECG & urine MAU estimation

12. Incl.Crit: Asymptomatic adults aged > 18yrs with a BP of >140/90 mm Hg

13. Mean age of patients having MAU : 56.29 ± 9.07 yrs.

14. Prevalence of MAU ↑ with age [38.88% in 31-40yrs vs 61.53% in >60yrs]

15. Disease duration of >9yrs: 58.33% vs 18.75% with a duration of 4-6 yrs63.

16. 63% of male obese had MAU vs 25% of female obese.

17. Retinopathy : 62.5% of pts with MAU

18. Retinopathy prevalence ↑with the severity of Htn. [47.6% among Stage II Htnwith MAU vs16.6% among Stage I Htn]

19. ECG changes of LVH.: 79.16%

20. MAU : low HDL[<40mg/ml]75%, high LDL [>150mg/dl] 79.16%.

21. MAU: no correlation with CrCl.REFERENCES †Olsen MH, Wachtell K, Borch-Johnsen K, Okin PM, Kjeldsen SE, Dahlof B, Devereux RB, Ibsen HA:. Losartan Intervention For Endpoint reduction. J Hum Hypertens 16: 591 595, 2002