1. Lyme disease a zoonotic the genus Ixodes, and enter host treatment of the disease in dogs and
endemic disease and is characterized by organisms during feeding through the cattle. Typically in the acute stage of
erythematic margins & potential tick saliva of the infected ticks. In the disease, dairy cattle may develop
bite history . It is caused by infection susceptible animals these bacteria can fever, stiffness and swollen joints,
with the bacteria Borrelia burgdorferi. reside in many types of tissue (e. g., lameness, and their milk production
Borrelia belong to a category of muscle, nervous). decreases. Chronic weight loss,
bacteria known as spirochetes, so laminitis, and abortion have also been
named because of their corkscrew-like reported. A rash may occur at the site
appearance. of the tick bite in some cases, but may
be difficult to see, if it occurs at all.
Synonym of Lyme Disease: Unfortunately, the clinical signs of
Borreliosis Lyme disease are very similar to other
diseases common in cattle and the
Epidemiology: symptoms vary greatly among cows.
Lyme disease has been reported Cross-reactivity to other organisms
in domestic animals, including dogs, similar to B. burgdorferi may lead to
horses, and more recently, cattle. Lyme false positive results in serological tests
disease is now the most common currently in use. As in humans, an
vector-borne infection in humans. accurate diagnosis must include a
Persons at risk for getting Lyme disease Incidence/prevalence history of potential exposure to the
are those who live, work, or visit parks In endemic areas (areas where vector tick (Ixodes scapularis),
in endemic areas and frequent sites the disease is most common) it is appropriate clinical signs, elevated
where infected ticks are common, such reported that up to 75% of dogs will antibody titers to specific borrelial
as wooded areas inhabited by white- test positive for exposure to Lyme antigens, and a positive response to
tailed deer. disease. It is believed that only 5-10% antibiotic treatment.
of these positive dogs will ever show
Lifecycle: clinical signs of the disease. In Human:
White-footed mice, Peromyscus Lyme disease is a multisystem
leucopus, are the principal reservoir Clinical symptom: illness involving the skin, nervous
hosts for B. burgdorferi. Causal agent system, heart, and joints. Initially,
is transmitted in ticks during feeding on In Animals : symptoms resemble the onset of
infected mice. Borrelia burgdorferi At the present time, there is no influenza. About 60% of Lyme disease
survive in the guts of certain ticks in set pattern of symptoms, diagnosis or patients present with a characteristic

2. "bull's eye" rash, or erythema migrans tests for antibodies but is not usually
(EM) which appears at the site of the done in routine practice.
tick bite usually within 3 days to 1
month after the bite of an infected tick.
Later stage symptoms may occur weeks
after a tick bite and are more severe,
including neurological complications
such as facial palsy, irritability, and
poor motor coordination. Further,
cardiac problems including irregular
heart beat and varying degrees of heart
blockage causing dizziness may
eventually occur. Third stage Lyme
disease can occur months or years after
the initial infection and may involve
chronic arthritis or chronic neurological
effects. Lyme disease is rarely, if ever
fatal. Prompt treatment with antibiotics Differential Diagnosis:
during early stages of the disease Injury, arthritis of other origin,
affords complete recovery. However, renal disease of other origin, nervous
later stages are more difficult to treat. system disease of other origin.
Diagnostic test: Prepared By: Submitted To:
Neelima Patel Dr.
IDEXX SNAP 3DX or SNAP B.V.Sc & A.H. Dept. of Vety.
4DX (C6 Peptide Antibody test) is an Batch ‘B’ Public Health
accurate test for antibodies indicating
exposure to the organism which can
also be used in vaccinated animals.
Quantitative C6 Peptide Antibody Test
determines the level of antibody
present and can be used to monitor
College Of Veterinary Science & A.H. Jabalpur
response to treatment. Western Blot
Affiliation: NDVSU, Jabalpur (M.P.)