1. Assessing Cost-Effectiveness (ACE) of interventions to reduce burden of harm from alcohol misuse: ACE Alcohol Associate Professor Chris Doran National Drug and Alcohol Research Centre, AUSTRALIA 2nd international conference on Public Health among Greater Mekong Sub-Regional countries

8. Model ACE-Alcohol model Epidemiological data Intervention data – costs – effects Disease & injury treatment costs Health gain (DALYs) Costs (AUS$) Cost-effectiveness ratio ($/DALY) Cost-effectiveness planes Acceptability curves Uncertainty analysis

9. Results Intervention DALYs averted Cost Offsets ($million) Intervention Cost ($million) Net Cost ($million) Median CER ($/DALY) Taxation 11,000 -$57 $0.58 -$56 Dominant Advertising bans 7,800 -$31 $20 -$12 Dominant Min. legal drink age to 21 150 -$0.8 $0.64 -$0.16 Dominant Licensing controls 2,700 -$11 $20 $8.7 $3,300 GP advice 160 -$1.2 $2.3 $1.1 $6,800 GP advice + telemarketing 340 -$2.6 $6.1 $3.5 $10,000 Drink driving mass media 1,500 -$11 $39 $28 $14,000 Random breath testing 2,300 -$17 $71 $54 $24,000 Res. treat. + naltrexone 460 -$4.4 $59 $55 $120,000 Residential treatment 190 -$1.7 $37 $35 $190,000 CER < $50,000 / DALY is cost-effective

11. Intervention pathway