CHEMISTRY OF ADDICTION
Alyssa Alicea
Preface
 When science began to study addictive
behavior in the 1930s, people addicted to
drugs were thought to be morally...
Preface
 Groundbreaking discoveries about the brain
have revolutionized our understanding of
drug addiction
 This enable...
Preface
 Scientists have been developing effective
prevention and treatment approaches that
reduce the toll drug abuse ta...
Introduction
 Addiction and abuse to alcohol, nicotine,
and illegal substances cost Americans half a
trillion dollars a y...
People of all ages suffer from the
abuse of drugs and alcohol
 Babies exposed to legal and illegal drugs
in the womb .
 ...
Prevention-best strategy
 Risk of drug abuse increases greatly during
times of transition, such as changing schools,
movi...
Prevention-best
strategy(cont.)
 Drug and alcohol abuse can
 Disrupt brain function
 Areas critical to motivation
 Mem...
Science-validated programs
 "science-validated" -programs rationally
designed, based on current knowledge,
rigorously tes...
How do these programs work??
 3 types
 Universal programs address risk and protective
factors common to all children in ...
 Cigarette smoking is at its lowest point since
NIDA began tracking it in 1975.
Human Brain.
 three-pound mass of gray and white matter
sits at the center of all human activity
 enables you to interpr...
Human Brain(cont.)-areas
affected by drug abuse
 The brain stem- heart rate, breathing, and
sleeping(basic functions).
 ...
 The cerebral cortex divided into areas that
control specific functions.
 Different areas process information from our
s...
How does the brain
communicate?
 communications center consisting of billions
of neurons, or nerve cells.
 Networks of n...
The human brain!
How drugs work on the brain
 Drugs are chemicals.
 They work in the brain by tapping into the
brain's communication syst...
 Some drugs, such as marijuana and heroin, can
activate neurons because their chemical
structure mimics that of a natural...
 Other drugs, such as amphetamine or cocaine,
can cause the nerve cells to release abnormally
large amounts of natural ne...
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Chemistry of addiction

  1. 1. CHEMISTRY OF ADDICTION Alyssa Alicea
  2. 2. Preface  When science began to study addictive behavior in the 1930s, people addicted to drugs were thought to be morally flawed and lacking in willpower.  Today, our views and our responses to drug abuse have changed dramatically.
  3. 3. Preface  Groundbreaking discoveries about the brain have revolutionized our understanding of drug addiction  This enables us to respond effectively to the problem.  Drug addiction is a DISEASE that affects brain and behavior
  4. 4. Preface  Scientists have been developing effective prevention and treatment approaches that reduce the toll drug abuse takes on individuals, families, and communities.
  5. 5. Introduction  Addiction and abuse to alcohol, nicotine, and illegal substances cost Americans half a trillion dollars a year  The abuse of illicit drugs and alcohol -death of more than 100,000 Americans.  Tobacco - linked to an estimated 440,000 deaths per year.
  6. 6. People of all ages suffer from the abuse of drugs and alcohol  Babies exposed to legal and illegal drugs in the womb .  born premature  underweight  Slowed intellectual development  Exposure can affect behavior later in life.
  7. 7. Prevention-best strategy  Risk of drug abuse increases greatly during times of transition, such as changing schools, moving, or divorce.  Teens' –still developing judgment and decision making skills  ability to assess risks accurately and make sound decisions about using drugs may be limited .
  8. 8. Prevention-best strategy(cont.)  Drug and alcohol abuse can  Disrupt brain function  Areas critical to motivation  Memory  Learning  Judgment  Behavior control
  9. 9. Science-validated programs  "science-validated" -programs rationally designed, based on current knowledge, rigorously tested, and shown to produce positive results.  science-validated programs can significantly reduce early use of tobacco, alcohol, and illicit drugs.
  10. 10. How do these programs work??  3 types  Universal programs address risk and protective factors common to all children in a given setting, such as a school or community.  Selective programs target groups of children and teens who have factors that further increase their risk of drug abuse.  Indicated programs are designed for youth who have already begun abusing drugs.
  11. 11.  Cigarette smoking is at its lowest point since NIDA began tracking it in 1975.
  12. 12. Human Brain.  three-pound mass of gray and white matter sits at the center of all human activity  enables you to interpret and respond to everything you experience  shapes thoughts, emotions, and behavior. Drugs can alter important brain areas that are necessary for life-sustaining functions and can drive the compulsive drug abuse that marks addiction.
  13. 13. Human Brain(cont.)-areas affected by drug abuse  The brain stem- heart rate, breathing, and sleeping(basic functions).  The limbic system contains the brain's reward circuit links brain structures that control and regulate our ability to feel enjoyment. Feeling delight motivates the repetition of behaviors ex. eating - actions that are critical to our existence. perception of emotions, positive and negative, which explains the mood-altering properties of many drugs.
  14. 14.  The cerebral cortex divided into areas that control specific functions.  Different areas process information from our senses, enabling us to see, feel, hear, and taste.  the frontal cortex or forebrain, is the thinking center of the brain, powers our ability to think, plan, solve problems, and make decisions.
  15. 15. How does the brain communicate?  communications center consisting of billions of neurons, or nerve cells.  Networks of neurons pass messages back and forth to different structures within the brain, the spinal column, and the peripheral nervous system.  nerve networks coordinate and regulate everything we think, feel, or do
  16. 16. The human brain!
  17. 17. How drugs work on the brain  Drugs are chemicals.  They work in the brain by tapping into the brain's communication system and interfering with the way nerve cells normally send, receive, and process information. .
  18. 18.  Some drugs, such as marijuana and heroin, can activate neurons because their chemical structure mimics that of a natural neurotransmitter.This similarity in structure "fools" receptors and allows the drugs to lock onto and activate the nerve cells. Although these drugs mimic brain chemicals, they don't activate nerve cells in the same way as a natural neurotransmitter, and they lead to abnormal messages being transmitted through the network.
  19. 19.  Other drugs, such as amphetamine or cocaine, can cause the nerve cells to release abnormally large amounts of natural neurotransmitters or prevent the normal recycling of these brain chemicals.This disruption produces a greatly amplified message, ultimately disrupting communication channels.The difference in effect can be described as the difference between someone whispering into your ear and someone shouting into a microphone.

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