Comfortis kills adult fleas on cats and kittens. Existing flea infestations are treated and future ones prevented over the period of one month with Comfortis.

1. Comfortis For Cats to Prevent and Treat Flea Infestations
PRODUCT INFO
Comfortis flavored chewable tablets for cats are used to prevent and treat flea infestations.
WHAT THIS PRODUCT CURES
Comfortis kills adult fleas on cats and kittens. Existing flea infestations are treated and future
ones prevented over the period of one month with
Comfortis.
PET SYMPTOMS
Fleas are non-flying parasitic insects feeding on
blood of animals and humans. Within 24 hours
after their first meal on a new host, fleas lay large
number of eggs (40 to 50 per day). In order to
maintain that high rate of fertility, fleas must feed
on blood regularly. Over the short period of two to
three weeks, eggs complete their life cycle through four stages, finally developing into adult
fleas. They are visible by naked eye, but very small (usually appearing as small moving dots
between the fur hairs of the cat) and usually difficult to detect. Although they are unable to
fly, they posses extraordinary jumping abilities. In order to feed on blood, fleas must pierce
the surface of the skin. Those actions are the
source of severe discomfort for cats, causing
them to constantly scratch, chew and bite the
affected areas of the skin. Areas around head,
neck and around the tail are commonly affected.
As the result of constant biting and scratching
the skin becomes inflamed and red. “Flea
feces”, consisted of undigested blood, is often
the only visible sign of flea infestation that
owners detect in their pets’ fur. Flea infestations
can lead to flea allergy dermatitis and further
skin issues. Fleas can also transmit certain diseases via bite wounds and cause other serious
health problems in younger animals and sometimes even in humans.

2. PET AILMENTS
Aside from skin irritation that is a source of severe discomfort for the cat, the constant licking
and chewing of the affected body areas can lead to serious skin infections that sometimes
require antibiotic treatment. Cats can become allergic to saliva of the fleas. Flea allergy
dermatitis is one of the most common cat skin disorders. Severe flea infestations can lead to
anemia, especially in younger or previously sick animals. Fleas can transmit tapeworm
infections between animals.
RELATIVE INFO ON BREEDS MOST ASSOCIATED WITH THIS AILMENT
There is no known breed predisposition for flea infestation among cat population. Animals
kept in inadequate hygienic conditions are more susceptible to flea infestation regardless of
their breed, age or size.
QUESTIONS FOR MY VET
1. What is the best time of the year to treat my cat with Comfortis?
a) You can begin treatment with Comfortis at any time of the year. For achieving the best
results, it is recommended to give Comfortis one month before the fleas are expected to
become active. Monthly dosing should be repeated throughout the flea season. In areas where
fleas are active through the entire year it is recommended to treat pets regularly every month
without interruptions.
2. Should I treat other pets in my household with Comfortis?
a) In order to prevent possible re-infestations, it is necessary to treat all pets susceptible to flea
infestations in your household. There are appropriate Comfortis formulations for dogs and for
cats available on the market.
3. How are Comfortis chewable tablets administered?

3. Comfortis chewable tablets are flavored, which makes them easier to administer. It is best to
offer the Comfortis chewable tablet before the usual meal. If the animal is reluctant to ingest
the tablet, it can be offered in food or administered as other tablet medications. In such cases
you are required to open the cat’s mouth and place the tablet as far back over the tongue as
possible, immediately closing the mouth to prevent spitting of the tablet.
4. I’ve missed a scheduled dose of Comfortis? What should I do?
Administer Comfortis chewable tablets as soon you realize you’ve missed a scheduled dose.
After that, resume the recommended monthly schedule, and administer Comfortis regularly
every month.
5. What should I do if my pet vomits soon after the ingestion of Comfortis chewable tablet?
If your pets vomits within an hour of Comfortis ingestion, you will need to repeat the
administration and give your pet another full dose.
6. Are there any adverse reactions to Comfortis I should be aware of?
According to the recent studies, there are no serious adverse reactions to Comfortis chewable
tablets. If there are detectable adverse reactions, they are mild and rarely occurring. Vomiting
is most common adverse reactions recorded in cats using Comfortis. Decreased appetite,
lethargy and diarrhea can rarely be seen. If you notice any of mentioned adverse reactions,
feel free to consult with your veterinarian.
7. Can I administer Comfortis chewable tablets to a young kitten?
It is not recommended to administer Comfortis chewable tablets to kittens younger than 14
weeks due to possible adverse reactions. Choose some of the other available flea prevention
methods after consulting with your veterinarian.
8. Is Comfortis safe for my pet?
Comfortis is proven to be safe if given to healthy cats, according to the label instructions.
Kittens younger than 14 weeks or lighter than 2 pounds should not be treated with Comfortis.
Safe use of Comfortis in pregnant or lactating queens and breeding males has not been
confirmed.
9. How soon can I expect the Comfortis to start killing fleas?
Comfortis chewable tablets are guaranteed to kill the fleas before they can begin to lay eggs.
Active ingredient of Comfortis, spinosad, is expected to start killing fleas within half an hour
of tablet ingestion and reaches its maximum capacity within 24 after administration of
chewable tablet, killing 100% of fleas.
10. I see fleas on my pet even after the administration of Comfortis? Is the treatment
working?

4. The fleas you are seeing are most likely the new fleas, since Comfortis kills fleas before they
can begin to lay eggs. Those new fleas will be killed before they can produce eggs. The
reason you saw new fleas on your pet is because it has been exposed to the infestation source.
You need to make sure that all animals in your household are also treated with approved flea
product. In order to keep your home free from fleas, vacuum frequently, launder sheets,
pillows and blankets regularly and steam clean carpets.
HOW IT WORKS
Active ingredient of Comfortis, spinosad, is a member of spynosins insecticide class. They are
non-antibacterial tetracyclic macrolides. Spinosad kills the fleas by causing the
hyperexcitation of their nervous system. Every formulation of Comfortis for cats provides the
minimum of 22.5 mg/lb of spinosad necessary to effectively kill the fleas. Fleas are killed
before they manage to lay eggs on the skin of the treated animal. Spinosad effect usually
begins within 30 minutes of tablet ingestion and lasts for 30 days, when the treatment needs to
be repeated.
DIRECTIONS FOR USE
Federal law makes it mandatory for the user to use the product strictly as per the instructions
contained in the packaging. It should be used in cats only.
Comfortis for cats is chewable tablets to intend for oral application. They are flavored,
which makes the administration easier. It is best to offer the tablet before or after the usual
meal. If the cat is reluctant to ingest the Comfortis tablet, it can be given in food or as any
other tablet medication.
DOSAGE AND ADMINISTRATION
Body Weight Spinosad Per Tablet (mg) Tablets Administered
2-4 lbs
90
One
4.1 to 6 lbs
140
One
6.1 to 12 lbs
270
One
12.1 to 24 lbs
560
One

5. Spinosad chewable tablets are available in four tablet sizes for cats and kittens according to
their body weight. The recommended minimum dosage of spinosad is 22.5 mg/lb (50mg/kg).
It is administered orally once a month.
INGREDIENTS
Spinosad chewable tablets, depending on their size, contain 90, 140, 270 or 560 mg of
spinosad. Every tablet also contains inactive ingredients: cellulose, microcrystalline,
hydroxypropyl cellulose, croscarmellose sodium, silicon dioxide, magnesium stearate and
water.
PRODUCT CAUTIONS
This product is intended for animal use only; not for use in humans.
Store away from children and other animals.
Do not administer more often than once a month; use strictly according to the label
instructions.
Do not use in kittens younger than 14 months or lighter than 2 pounds.
Comfortis should be used with caution in pregnant queens; seek veterinary advice on
this matter.
Safety of Comfortis administration in breeding male cats has not been confirmed.
STORAGE AND DISPOSAL
Store at 20-25°C; temporary periods of time outside of this temperature range between 1530°C are allowed.
BRAND VS GENERIC COMPARISON
Comfortis is a convenient, fast-acting and long-lasting flea control formulation. Competitors
of the name brand Comfortis use the same active ingredients, but may be somewhat more
expensive. Similar formulations of competitive brands are sometimes combined with other
anti-parasitic agents and can therefore cause numerous additional adverse reactions.
Competitive brands may offer flea protection as long lasting as Comfortis.
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