Company Overview✴ Founded in 1999✴ Over 5,000 systems installed✴ Headquartered in Mountain View, CA – Sales & support: USA, Germany & Canada – Distributed in over 70 countries✴ Financial – Revenue greater than 20% growth – Profitable Q4 2011✴ 125 Employees – More than 12% of revenue invested in R&D
Management Team Tim Marcotte P.J. Ryland COO VP Business Development and Corporate Accounts Recent Experience: Recent Experience: VNUS Medical Technologies Siemens, AcusonGlen McLaughlin, Ph.D. Scott WilliamsFounder & CTO Sr. Director Global ServiceRecent Experience: Recent Experience:Cardiac Pathways Siemens, AcusonMichael Gabler Dan TibbetsVP Engineering Sr. Director ManufacturingRecent Experience: Recent Experience:Aptix Corporation Lamb Research, Boston ScientificDoug TefftVP InternationalRecent Experience:SonoSite, ATL
ZONESonographyTM Technology(ZST) will become the next industrystandard method of generating ultrasound images as it is overcominga number of the barriers of digital beamformation.ZST is two generations aheadof traditional digital beamformationtechnology.— Frost & Sullivan 2011 Technology: ✴ Fast image acquisition ✴ Continuous transmit / receive focus ✴ Channel and RF data
Digital Beamformation Zone SonographyFast image acquisition provides Acoustic Currency✴Improved temporal accuracy✴Multiple modalities without compromise
Temporal image coherence No Motion Artifact Motion Artifact due to fast due to slow shutter speed shutter speed
Continuous Transmit / Receive focus Transmit provides better contrast resolution (-50 dB) Zone Sonography Beamformer Receive provides better detail resolution Technology Technology (-20 dB) No need to blend multiple Tx focus zone images Independent Nyquist samplingrequirements for Transmit and Receive Applicable for all multi dimensionalimaging modalities ✴Image Benefits: -Improved detail resolution -Improved contrast resolution Legend -Improved penetration -Better uniformity PSF -Improved Doppler sensitivity
Zone Sonogaphy Beamformer Technology Technology PSF
Zone Sonography Technology Beamformer Technology
CW CD Scale CD-Mode to SettingsChannel and RF data enables PowerPatient Specific Imaging✴ Sound speed correction B-Mode I/Q PW-Mode Settings Data Settings✴ Retrospective imaging capabilities Set✴ Enhanced auto optimization capabilities Elastography Auto Optimize Contrast Settings
Patient Specific ImagingVariability of sound speed withinpatients lead to lower detail andcontrast resolution resulting indecreased diagnostic confidence V > 1540 m/ssound speed correction reduces image V= 1540 m/svariability across patients V < 1540 m/s
Corrected SS (1540 m/s) Assumed (1480 Patient SpecificImaging (Phantom)
Patient Specific Imaging (Phantom) Corrected SS (1480 m/s) Assumed SS (1540 m/s)
Interventional Radiology✴ Premium image performance – Dynamic transmit / receive focus – Acoustic currency – Patient specific imaging✴ Full transducer offering – L8-3, L10-5, L14-5sp, L14- 5w, C9-3, C6-2 & P4-1c✴ One touch image optimization✴ Intuitive user interface✴ Full screen display capabilities✴ Battery powered (3-hours)✴ Highly mobile
Emergency Department✴ Premium image performance – Dynamic transmit / receive focus – Acoustic currency – Patient specific imaging✴ Full transducer offering – L8-3, P4-1c, C4-1 & E9-4✴ Intuitive user interface✴ Full screen display capabilities✴ One touch image optimization✴ Battery powered (3-hours)✴ Highly mobile✴ Accreditation, reporting & billing packages
Clinical AssessmentSuperior performance fromneonates to bariatrics
Clinical Assessment: Cincinnati Children’s Hospital As an international leader in improving child health, Cincinnati Children’ s Hospital Medical Center is one of the largest pediatric radiology facilities in the country, performing more than 200,000 imaging procedures each year. Clinical procedures and treatments pioneered at Cincinnati Children’s are used throughout the world. U.S. News & World Report has ranked Cincinnati Children’ s the third best children’s hospital in the nation in general pediatrics in its 2011-12
14 day neonate coronal viewCompetitive Premium System ZONARE
Left kidney in 1 month neonateCompetitive Premium System ZONARE
Right kidney transverse, abscessCompetitive Premium System ZONARE
Patent IVC post liver transplant in 9 year old Competitive Premium System ZONARE
Obese 16 year old liver / kidneyCompetitive Premium System ZONARE
Brian Coley Radiologist-in-Chief, Cincinnati Children’ s Hospital Medical Center“In my experience, the highly mobile ZONARE ultrasoundsystem delivers premium pediatric imaging performancein practical applications. Using the C10-3, C9-3, and C6-2transducers, ZONARE provides consistently uniformimaging at depth on neonates to difficult to imageteenagers, with color Doppler performance comparable toour other premium systems” said Dr. Coley.
Clinical Assessment: Winnipeg’s Health Science CenterWinnipeg’s Health Science Centre is the largesthealth care referral, teaching and research centerserving residents of Manitoba, NorthwesternOntario and Nunavut and is one of the largestfacilities of its kind in Canada. The ultrasounddepartment conducts approximately 18,000exams annually and is dedicated to providingquality imaging using the most advancedtechnology available.
Edward Lyons Professor and Past Chairman of Radiology, Professor of Obstetrics and Gynecology“When imaging the liver in large patients withZONARE’s C6-2 and C4-1 probes, I feel thatthe penetration and image quality is equivalentto what I have seen on premium scannersusing similar probe technology,” said Dr. Lyons.