SlideShare a Scribd company logo

A Herbert

•
•
Pierre Trudelle
Pierre Trudelle

Conférence inaugurale (JFK2009)

1 of 16
WHEN AND HOW SHOULD NEW THERAPIES BECOME ROUTINE CLINICAL PRACTICE? Rob Herbert, Senior Research Fellow
Background ,[object Object],[object Object],[object Object]
[object Object]
Stages in the career of a medical innovation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],McKinlay JB (1981) Millbank Mem Fund Quart
What is so special about randomised trials? ,[object Object]
A case study ,[object Object],[object Object]
A case study Sapsford R (2001) APMR 82: 1081-8 ,[object Object]
A case study ,[object Object],[object Object]
A case study ,[object Object],[object Object],Dumoulin C (2004) Obs & Gyn 104: 504-10
Recommendations ,[object Object],[object Object],DISSEMINATION ,[object Object],TESTING ,[object Object],[object Object],[object Object],DEVELOPMENT ,[object Object]
Anticipation of objections ,[object Object],[object Object],[object Object]
Anticipation of objections ,[object Object]
www.pedro.fhs.org.au
Anticipation of objections ,[object Object],[object Object],[object Object]
Anticipation of objections ,[object Object],[object Object]
Summary ,[object Object],[object Object]

Recommended

Novel method for reviewing mechanistic evidence on diet, nutrition, physical ...
Novel method for reviewing mechanistic evidence on diet, nutrition, physical ...Novel method for reviewing mechanistic evidence on diet, nutrition, physical ...
Novel method for reviewing mechanistic evidence on diet, nutrition, physical ...World Cancer Research Fund International
 
Module 4 Submodule 4. 2 Final June 2007
Module 4 Submodule 4. 2 Final June 2007Module 4 Submodule 4. 2 Final June 2007
Module 4 Submodule 4. 2 Final June 2007Flavio Guzmán
 
27.SAR 2014
27.SAR 201427.SAR 2014
27.SAR 2014nishiburute
 
Copeptin
CopeptinCopeptin
CopeptinYassin Alsaleh
 
Implementation of a Non-Pharmacological Sleep Hygiene Routine Program to Impr...
Implementation of a Non-Pharmacological Sleep Hygiene Routine Program to Impr...Implementation of a Non-Pharmacological Sleep Hygiene Routine Program to Impr...
Implementation of a Non-Pharmacological Sleep Hygiene Routine Program to Impr...SadafFatima45
 
is laser treatment is really a good decision for a women????think...Impact of...
is laser treatment is really a good decision for a women????think...Impact of...is laser treatment is really a good decision for a women????think...Impact of...
is laser treatment is really a good decision for a women????think...Impact of...ShitalSavaliya1
 
Impact of Weight Change on Cancer Prognosis - Professor Andrew G Renehan
Impact of Weight Change on Cancer Prognosis - Professor Andrew G RenehanImpact of Weight Change on Cancer Prognosis - Professor Andrew G Renehan
Impact of Weight Change on Cancer Prognosis - Professor Andrew G RenehanWorld Cancer Research Fund International
 
public health _03302015 resized
public health _03302015 resizedpublic health _03302015 resized
public health _03302015 resizedZakkoyya Lewis
 

Recommended

Novel method for reviewing mechanistic evidence on diet, nutrition, physical ...
Novel method for reviewing mechanistic evidence on diet, nutrition, physical ...Novel method for reviewing mechanistic evidence on diet, nutrition, physical ...
Novel method for reviewing mechanistic evidence on diet, nutrition, physical ...World Cancer Research Fund International
 
Module 4 Submodule 4. 2 Final June 2007
Module 4 Submodule 4. 2 Final June 2007Module 4 Submodule 4. 2 Final June 2007
Module 4 Submodule 4. 2 Final June 2007Flavio Guzmán
 
27.SAR 2014
27.SAR 201427.SAR 2014
27.SAR 2014nishiburute
 
Copeptin
CopeptinCopeptin
CopeptinYassin Alsaleh
 
Implementation of a Non-Pharmacological Sleep Hygiene Routine Program to Impr...
Implementation of a Non-Pharmacological Sleep Hygiene Routine Program to Impr...Implementation of a Non-Pharmacological Sleep Hygiene Routine Program to Impr...
Implementation of a Non-Pharmacological Sleep Hygiene Routine Program to Impr...SadafFatima45
 
is laser treatment is really a good decision for a women????think...Impact of...
is laser treatment is really a good decision for a women????think...Impact of...is laser treatment is really a good decision for a women????think...Impact of...
is laser treatment is really a good decision for a women????think...Impact of...ShitalSavaliya1
 
Impact of Weight Change on Cancer Prognosis - Professor Andrew G Renehan
Impact of Weight Change on Cancer Prognosis - Professor Andrew G RenehanImpact of Weight Change on Cancer Prognosis - Professor Andrew G Renehan
Impact of Weight Change on Cancer Prognosis - Professor Andrew G RenehanWorld Cancer Research Fund International
 
public health _03302015 resized
public health _03302015 resizedpublic health _03302015 resized
public health _03302015 resizedZakkoyya Lewis
 
Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...
Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...
Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...enchantingfeud562
 
Scott Harris
Scott HarrisScott Harris
Scott HarrisConferenceForum
 
Agreeing what outcomes to measure
Agreeing what outcomes to measureAgreeing what outcomes to measure
Agreeing what outcomes to measureEURORDIS Rare Diseases Europe
 
Nejm journal watch practice changing articles 2014
Nejm journal watch practice changing articles 2014Nejm journal watch practice changing articles 2014
Nejm journal watch practice changing articles 2014Jaime dehais
 
Antiemetic bolus vs drip in oncology dwi ambar
Antiemetic bolus vs drip in oncology dwi ambarAntiemetic bolus vs drip in oncology dwi ambar
Antiemetic bolus vs drip in oncology dwi ambarRaafqi Ranasasmita
 
Value of Transferability and Efficiency in HTA
Value of Transferability and Efficiency in HTA Value of Transferability and Efficiency in HTA
Value of Transferability and Efficiency in HTA Office of Health Economics
 
Peyronie's drug
Peyronie's drugPeyronie's drug
Peyronie's drugInstitute for the Study of Urologic Diseases
 
Easier said than done: experiences and challenges in natural experimental eva...
Easier said than done: experiences and challenges in natural experimental eva...Easier said than done: experiences and challenges in natural experimental eva...
Easier said than done: experiences and challenges in natural experimental eva...dbogilvie
 
UOG Journal Club: Second-trimester uterine artery Doppler in risk for pre-ecl...
UOG Journal Club: Second-trimester uterine artery Doppler in risk for pre-ecl...UOG Journal Club: Second-trimester uterine artery Doppler in risk for pre-ecl...
UOG Journal Club: Second-trimester uterine artery Doppler in risk for pre-ecl...International Society of Ultrasound in Obstetrics and Gynecology (ISUOG)
 
Role of pmft in oab
Role of pmft in oabRole of pmft in oab
Role of pmft in oabArsla Memon
 
Identifying and Managing Pre-Diabetes: A systematic review of screening and i...
Identifying and Managing Pre-Diabetes: A systematic review of screening and i...Identifying and Managing Pre-Diabetes: A systematic review of screening and i...
Identifying and Managing Pre-Diabetes: A systematic review of screening and i...UKFacultyPublicHealth
 
Topical corticosteroids as adjunctive therapy for bacterial keratitis
Topical corticosteroids as adjunctive therapy for bacterial keratitisTopical corticosteroids as adjunctive therapy for bacterial keratitis
Topical corticosteroids as adjunctive therapy for bacterial keratitisHari Prakash
 
A distributed data mining network infrastructure for Australian radiotherapy ...
A distributed data mining network infrastructure for Australian radiotherapy ...A distributed data mining network infrastructure for Australian radiotherapy ...
A distributed data mining network infrastructure for Australian radiotherapy ...Cancer Institute NSW
 
What is the importance of calculating sample size?
What is the importance of calculating sample size?What is the importance of calculating sample size?
What is the importance of calculating sample size?Cecilia M. Patino-Sutton, MD MeD PhD
 
ASTUTE: Acute Stroke Telemedicine
ASTUTE: Acute Stroke TelemedicineASTUTE: Acute Stroke Telemedicine
ASTUTE: Acute Stroke TelemedicineNHS Improving Quality
 
Fibroids & fertility
Fibroids & fertilityFibroids & fertility
Fibroids & fertilityMarmara University School of Medicine
 
Does Adherence to Lipid Lowering Therapy Predict Higher Initial CPAP 5.21.08
Does Adherence to Lipid Lowering Therapy Predict Higher Initial CPAP 5.21.08Does Adherence to Lipid Lowering Therapy Predict Higher Initial CPAP 5.21.08
Does Adherence to Lipid Lowering Therapy Predict Higher Initial CPAP 5.21.08Leonard Davis Institute of Health Economics
 
MicroGuide app, pop up uni, 1pm, 3 september 2015
MicroGuide app, pop up uni, 1pm, 3 september 2015MicroGuide app, pop up uni, 1pm, 3 september 2015
MicroGuide app, pop up uni, 1pm, 3 september 2015NHS England
 
Ispor workshop value-based_assess_nice_kks_nov2014
Ispor workshop value-based_assess_nice_kks_nov2014Ispor workshop value-based_assess_nice_kks_nov2014
Ispor workshop value-based_assess_nice_kks_nov2014Office of Health Economics
 
WCPT2011
WCPT2011WCPT2011
WCPT2011Pierre Trudelle
 
B Moore Presentation 07 01 09
B Moore Presentation 07 01 09B Moore Presentation 07 01 09
B Moore Presentation 07 01 09Pierre Trudelle
 
Pinelli jfk2011
Pinelli jfk2011Pinelli jfk2011
Pinelli jfk2011Pierre Trudelle
 

More Related Content

What's hot

Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...
Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...
Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...enchantingfeud562
 
Nejm journal watch practice changing articles 2014
Nejm journal watch practice changing articles 2014Nejm journal watch practice changing articles 2014
Nejm journal watch practice changing articles 2014Jaime dehais
 
Antiemetic bolus vs drip in oncology dwi ambar
Antiemetic bolus vs drip in oncology dwi ambarAntiemetic bolus vs drip in oncology dwi ambar
Antiemetic bolus vs drip in oncology dwi ambarRaafqi Ranasasmita
 
Value of Transferability and Efficiency in HTA
Value of Transferability and Efficiency in HTA Value of Transferability and Efficiency in HTA
Value of Transferability and Efficiency in HTA Office of Health Economics
 
Easier said than done: experiences and challenges in natural experimental eva...
Easier said than done: experiences and challenges in natural experimental eva...Easier said than done: experiences and challenges in natural experimental eva...
Easier said than done: experiences and challenges in natural experimental eva...dbogilvie
 
Role of pmft in oab
Role of pmft in oabRole of pmft in oab
Role of pmft in oabArsla Memon
 
Identifying and Managing Pre-Diabetes: A systematic review of screening and i...
Identifying and Managing Pre-Diabetes: A systematic review of screening and i...Identifying and Managing Pre-Diabetes: A systematic review of screening and i...
Identifying and Managing Pre-Diabetes: A systematic review of screening and i...UKFacultyPublicHealth
 
Topical corticosteroids as adjunctive therapy for bacterial keratitis
Topical corticosteroids as adjunctive therapy for bacterial keratitisTopical corticosteroids as adjunctive therapy for bacterial keratitis
Topical corticosteroids as adjunctive therapy for bacterial keratitisHari Prakash
 
A distributed data mining network infrastructure for Australian radiotherapy ...
A distributed data mining network infrastructure for Australian radiotherapy ...A distributed data mining network infrastructure for Australian radiotherapy ...
A distributed data mining network infrastructure for Australian radiotherapy ...Cancer Institute NSW
 
MicroGuide app, pop up uni, 1pm, 3 september 2015
MicroGuide app, pop up uni, 1pm, 3 september 2015MicroGuide app, pop up uni, 1pm, 3 september 2015
MicroGuide app, pop up uni, 1pm, 3 september 2015NHS England
 
Ispor workshop value-based_assess_nice_kks_nov2014
Ispor workshop value-based_assess_nice_kks_nov2014Ispor workshop value-based_assess_nice_kks_nov2014
Ispor workshop value-based_assess_nice_kks_nov2014Office of Health Economics
 

What's hot (19)

Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...
Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...
Foundation for Chiropractic Progress: Study Shows Acetaminophen Ineffective i...
 
Scott Harris
Scott HarrisScott Harris
Scott Harris
 
Agreeing what outcomes to measure
Agreeing what outcomes to measureAgreeing what outcomes to measure
Agreeing what outcomes to measure
 
Nejm journal watch practice changing articles 2014
Nejm journal watch practice changing articles 2014Nejm journal watch practice changing articles 2014
Nejm journal watch practice changing articles 2014
 
Antiemetic bolus vs drip in oncology dwi ambar
Antiemetic bolus vs drip in oncology dwi ambarAntiemetic bolus vs drip in oncology dwi ambar
Antiemetic bolus vs drip in oncology dwi ambar
 
Value of Transferability and Efficiency in HTA
Value of Transferability and Efficiency in HTA Value of Transferability and Efficiency in HTA
Value of Transferability and Efficiency in HTA
 
Peyronie's drug
Peyronie's drugPeyronie's drug
Peyronie's drug
 
Easier said than done: experiences and challenges in natural experimental eva...
Easier said than done: experiences and challenges in natural experimental eva...Easier said than done: experiences and challenges in natural experimental eva...
Easier said than done: experiences and challenges in natural experimental eva...
 
UOG Journal Club: Second-trimester uterine artery Doppler in risk for pre-ecl...
UOG Journal Club: Second-trimester uterine artery Doppler in risk for pre-ecl...UOG Journal Club: Second-trimester uterine artery Doppler in risk for pre-ecl...
UOG Journal Club: Second-trimester uterine artery Doppler in risk for pre-ecl...
 
Role of pmft in oab
Role of pmft in oabRole of pmft in oab
Role of pmft in oab
 
Identifying and Managing Pre-Diabetes: A systematic review of screening and i...
Identifying and Managing Pre-Diabetes: A systematic review of screening and i...Identifying and Managing Pre-Diabetes: A systematic review of screening and i...
Identifying and Managing Pre-Diabetes: A systematic review of screening and i...
 
Topical corticosteroids as adjunctive therapy for bacterial keratitis
Topical corticosteroids as adjunctive therapy for bacterial keratitisTopical corticosteroids as adjunctive therapy for bacterial keratitis
Topical corticosteroids as adjunctive therapy for bacterial keratitis
 
A distributed data mining network infrastructure for Australian radiotherapy ...
A distributed data mining network infrastructure for Australian radiotherapy ...A distributed data mining network infrastructure for Australian radiotherapy ...
A distributed data mining network infrastructure for Australian radiotherapy ...
 
What is the importance of calculating sample size?
What is the importance of calculating sample size?What is the importance of calculating sample size?
What is the importance of calculating sample size?
 
ASTUTE: Acute Stroke Telemedicine
ASTUTE: Acute Stroke TelemedicineASTUTE: Acute Stroke Telemedicine
ASTUTE: Acute Stroke Telemedicine
 
Fibroids & fertility
Fibroids & fertilityFibroids & fertility
Fibroids & fertility
 
Does Adherence to Lipid Lowering Therapy Predict Higher Initial CPAP 5.21.08
Does Adherence to Lipid Lowering Therapy Predict Higher Initial CPAP 5.21.08Does Adherence to Lipid Lowering Therapy Predict Higher Initial CPAP 5.21.08
Does Adherence to Lipid Lowering Therapy Predict Higher Initial CPAP 5.21.08
 
MicroGuide app, pop up uni, 1pm, 3 september 2015
MicroGuide app, pop up uni, 1pm, 3 september 2015MicroGuide app, pop up uni, 1pm, 3 september 2015
MicroGuide app, pop up uni, 1pm, 3 september 2015
 
Ispor workshop value-based_assess_nice_kks_nov2014
Ispor workshop value-based_assess_nice_kks_nov2014Ispor workshop value-based_assess_nice_kks_nov2014
Ispor workshop value-based_assess_nice_kks_nov2014
 

Viewers also liked

B Moore Presentation 07 01 09
B Moore Presentation 07 01 09B Moore Presentation 07 01 09
B Moore Presentation 07 01 09Pierre Trudelle
 
Consumer Experience Report - The Razorfish
Consumer Experience Report - The RazorfishConsumer Experience Report - The Razorfish
Consumer Experience Report - The RazorfishRafael Menoya
 
The Mental Measurements Yearbook
The Mental Measurements YearbookThe Mental Measurements Yearbook
The Mental Measurements YearbookAmanda Lemon
 
VisiRun Localizzatore satellitare GPS in tempo reale e controllo satellitare...
VisiRun Localizzatore satellitare GPS in tempo reale e controllo satellitare... VisiRun Localizzatore satellitare GPS in tempo reale e controllo satellitare...
VisiRun Localizzatore satellitare GPS in tempo reale e controllo satellitare...Selyon
 
Intervento al vega 26 nov2010
Intervento al vega 26 nov2010Intervento al vega 26 nov2010
Intervento al vega 26 nov2010Marco Zamperini
 
Marco Zamperini al ToscanaLab
Marco Zamperini al ToscanaLabMarco Zamperini al ToscanaLab
Marco Zamperini al ToscanaLabMarco Zamperini
 
Dr. Steele's NURS 1221 Course
Dr. Steele's NURS 1221 CourseDr. Steele's NURS 1221 Course
Dr. Steele's NURS 1221 CourseAmanda Lemon
 
29 de Abril-Día del Animal
29 de Abril-Día del Animal29 de Abril-Día del Animal
29 de Abril-Día del AnimalAdela Diez
 
Modulo Instruccional (645)
Modulo Instruccional (645)Modulo Instruccional (645)
Modulo Instruccional (645)nina987
 
Những tay tiếp thị đều nói xạo
Những tay tiếp thị đều nói xạoNhững tay tiếp thị đều nói xạo
Những tay tiếp thị đều nói xạobizpirate
 
Add Recording Links
Add Recording LinksAdd Recording Links
Add Recording Linksirsarahbean
 

Viewers also liked (18)

WCPT2011
WCPT2011WCPT2011
WCPT2011
 
B Moore Presentation 07 01 09
B Moore Presentation 07 01 09B Moore Presentation 07 01 09
B Moore Presentation 07 01 09
 
Pinelli jfk2011
Pinelli jfk2011Pinelli jfk2011
Pinelli jfk2011
 
Albasini jfk2011
Albasini jfk2011Albasini jfk2011
Albasini jfk2011
 
Consumer Experience Report - The Razorfish
Consumer Experience Report - The RazorfishConsumer Experience Report - The Razorfish
Consumer Experience Report - The Razorfish
 
The Mental Measurements Yearbook
The Mental Measurements YearbookThe Mental Measurements Yearbook
The Mental Measurements Yearbook
 
هل تنزح الطفولة؟
هل تنزح الطفولة؟هل تنزح الطفولة؟
هل تنزح الطفولة؟
 
Paris 2009 Diabetes
Paris 2009 DiabetesParis 2009 Diabetes
Paris 2009 Diabetes
 
VisiRun Localizzatore satellitare GPS in tempo reale e controllo satellitare...
VisiRun Localizzatore satellitare GPS in tempo reale e controllo satellitare... VisiRun Localizzatore satellitare GPS in tempo reale e controllo satellitare...
VisiRun Localizzatore satellitare GPS in tempo reale e controllo satellitare...
 
Intervento al vega 26 nov2010
Intervento al vega 26 nov2010Intervento al vega 26 nov2010
Intervento al vega 26 nov2010
 
Marco Zamperini al ToscanaLab
Marco Zamperini al ToscanaLabMarco Zamperini al ToscanaLab
Marco Zamperini al ToscanaLab
 
Dr. Steele's NURS 1221 Course
Dr. Steele's NURS 1221 CourseDr. Steele's NURS 1221 Course
Dr. Steele's NURS 1221 Course
 
ECED5153
ECED5153ECED5153
ECED5153
 
29 de Abril-Día del Animal
29 de Abril-Día del Animal29 de Abril-Día del Animal
29 de Abril-Día del Animal
 
Modulo Instruccional (645)
Modulo Instruccional (645)Modulo Instruccional (645)
Modulo Instruccional (645)
 
A P R E N D
A P R E N DA P R E N D
A P R E N D
 
Những tay tiếp thị đều nói xạo
Những tay tiếp thị đều nói xạoNhững tay tiếp thị đều nói xạo
Những tay tiếp thị đều nói xạo
 
Add Recording Links
Add Recording LinksAdd Recording Links
Add Recording Links
 

Similar to A Herbert

8-Clinical Trial Studies
8-Clinical Trial Studies8-Clinical Trial Studies
8-Clinical Trial StudiesResearchGuru
 
Importance of clinical trials in drug discovery
Importance of clinical trials in drug discoveryImportance of clinical trials in drug discovery
Importance of clinical trials in drug discoveryKarunaMane1
 
ERAS and regional anesthesia at PGA 2015
ERAS and regional anesthesia at PGA 2015ERAS and regional anesthesia at PGA 2015
ERAS and regional anesthesia at PGA 2015Colin McCartney
 
Grds international conference on social science (4)
Grds international conference on social science (4)Grds international conference on social science (4)
Grds international conference on social science (4)Global R & D Services
 
Family Planning for Persons Living with HIVAIDS_2015 AR and MS
Family Planning for Persons Living with HIVAIDS_2015 AR and MSFamily Planning for Persons Living with HIVAIDS_2015 AR and MS
Family Planning for Persons Living with HIVAIDS_2015 AR and MSNikole Gettings
 
How to have quality of life in Advanced ovarian malignancy
How to have quality of life in Advanced ovarian malignancyHow to have quality of life in Advanced ovarian malignancy
How to have quality of life in Advanced ovarian malignancyRajesh Gajbhiye
 
PERFORMING EMBRYO TRANSFER. ABOUBAKR ELNASHAR
PERFORMING EMBRYO TRANSFER. ABOUBAKR ELNASHARPERFORMING EMBRYO TRANSFER. ABOUBAKR ELNASHAR
PERFORMING EMBRYO TRANSFER. ABOUBAKR ELNASHARAboubakr Elnashar
 
To Determine Preference of Shoulder Pain Management by General Physicians in ...
To Determine Preference of Shoulder Pain Management by General Physicians in ...To Determine Preference of Shoulder Pain Management by General Physicians in ...
To Determine Preference of Shoulder Pain Management by General Physicians in ...suppubs1pubs1
 
Randomised Controlled Trials
Randomised Controlled TrialsRandomised Controlled Trials
Randomised Controlled Trialsfondas vakalis
 
Running head STATISTICAL ANALYSIS PROJECT ON POST-OPERATIVE N.docx
Running head STATISTICAL ANALYSIS PROJECT ON POST-OPERATIVE N.docxRunning head STATISTICAL ANALYSIS PROJECT ON POST-OPERATIVE N.docx
Running head STATISTICAL ANALYSIS PROJECT ON POST-OPERATIVE N.docxtoltonkendal
 
The Importance of Staying Active after a Cancer Diagnosis | Dr Anna Campbell
The Importance of Staying Active after a Cancer Diagnosis | Dr Anna CampbellThe Importance of Staying Active after a Cancer Diagnosis | Dr Anna Campbell
The Importance of Staying Active after a Cancer Diagnosis | Dr Anna CampbellScottish Cancer Prevention Network
 
Oxytocics and PPH management
Oxytocics and PPH managementOxytocics and PPH management
Oxytocics and PPH managementRajan Dubey
 
Does acupunture improve the outcome of in vitro fertilization
Does acupunture improve the outcome of in vitro fertilizationDoes acupunture improve the outcome of in vitro fertilization
Does acupunture improve the outcome of in vitro fertilizationmogollongarcia
 
ABC1 - L. Fallowfield - Differencies in side effects assessment among doctors...
ABC1 - L. Fallowfield - Differencies in side effects assessment among doctors...ABC1 - L. Fallowfield - Differencies in side effects assessment among doctors...
ABC1 - L. Fallowfield - Differencies in side effects assessment among doctors...European School of Oncology
 
Metoclopramide for nausea and vomiting prophylaxis during and
Metoclopramide for nausea and vomiting prophylaxis during andMetoclopramide for nausea and vomiting prophylaxis during and
Metoclopramide for nausea and vomiting prophylaxis during andMohd Mudassir
 
Clinical studies – a primer
Clinical studies – a primerClinical studies – a primer
Clinical studies – a primerMoshe Ben Yitzhak
 
Research methodology 101
Research methodology 101Research methodology 101
Research methodology 101Hesham Gaber
 
Cochrane reviews and guideline development: Is there anything new under the sun?
Cochrane reviews and guideline development: Is there anything new under the sun?Cochrane reviews and guideline development: Is there anything new under the sun?
Cochrane reviews and guideline development: Is there anything new under the sun?Health Informatics New Zealand
 

Similar to A Herbert (20)

8-Clinical Trial Studies
8-Clinical Trial Studies8-Clinical Trial Studies
8-Clinical Trial Studies
 
Importance of clinical trials in drug discovery
Importance of clinical trials in drug discoveryImportance of clinical trials in drug discovery
Importance of clinical trials in drug discovery
 
ERAS and regional anesthesia at PGA 2015
ERAS and regional anesthesia at PGA 2015ERAS and regional anesthesia at PGA 2015
ERAS and regional anesthesia at PGA 2015
 
Grds international conference on social science (4)
Grds international conference on social science (4)Grds international conference on social science (4)
Grds international conference on social science (4)
 
Family Planning for Persons Living with HIVAIDS_2015 AR and MS
Family Planning for Persons Living with HIVAIDS_2015 AR and MSFamily Planning for Persons Living with HIVAIDS_2015 AR and MS
Family Planning for Persons Living with HIVAIDS_2015 AR and MS
 
Chronic low-back pain
Chronic low-back painChronic low-back pain
Chronic low-back pain
 
How to have quality of life in Advanced ovarian malignancy
How to have quality of life in Advanced ovarian malignancyHow to have quality of life in Advanced ovarian malignancy
How to have quality of life in Advanced ovarian malignancy
 
PERFORMING EMBRYO TRANSFER. ABOUBAKR ELNASHAR
PERFORMING EMBRYO TRANSFER. ABOUBAKR ELNASHARPERFORMING EMBRYO TRANSFER. ABOUBAKR ELNASHAR
PERFORMING EMBRYO TRANSFER. ABOUBAKR ELNASHAR
 
To Determine Preference of Shoulder Pain Management by General Physicians in ...
To Determine Preference of Shoulder Pain Management by General Physicians in ...To Determine Preference of Shoulder Pain Management by General Physicians in ...
To Determine Preference of Shoulder Pain Management by General Physicians in ...
 
Randomised Controlled Trials
Randomised Controlled TrialsRandomised Controlled Trials
Randomised Controlled Trials
 
Running head STATISTICAL ANALYSIS PROJECT ON POST-OPERATIVE N.docx
Running head STATISTICAL ANALYSIS PROJECT ON POST-OPERATIVE N.docxRunning head STATISTICAL ANALYSIS PROJECT ON POST-OPERATIVE N.docx
Running head STATISTICAL ANALYSIS PROJECT ON POST-OPERATIVE N.docx
 
Cochrane
CochraneCochrane
Cochrane
 
The Importance of Staying Active after a Cancer Diagnosis | Dr Anna Campbell
The Importance of Staying Active after a Cancer Diagnosis | Dr Anna CampbellThe Importance of Staying Active after a Cancer Diagnosis | Dr Anna Campbell
The Importance of Staying Active after a Cancer Diagnosis | Dr Anna Campbell
 
Oxytocics and PPH management
Oxytocics and PPH managementOxytocics and PPH management
Oxytocics and PPH management
 
Does acupunture improve the outcome of in vitro fertilization
Does acupunture improve the outcome of in vitro fertilizationDoes acupunture improve the outcome of in vitro fertilization
Does acupunture improve the outcome of in vitro fertilization
 
ABC1 - L. Fallowfield - Differencies in side effects assessment among doctors...
ABC1 - L. Fallowfield - Differencies in side effects assessment among doctors...ABC1 - L. Fallowfield - Differencies in side effects assessment among doctors...
ABC1 - L. Fallowfield - Differencies in side effects assessment among doctors...
 
Metoclopramide for nausea and vomiting prophylaxis during and
Metoclopramide for nausea and vomiting prophylaxis during andMetoclopramide for nausea and vomiting prophylaxis during and
Metoclopramide for nausea and vomiting prophylaxis during and
 
Clinical studies – a primer
Clinical studies – a primerClinical studies – a primer
Clinical studies – a primer
 
Research methodology 101
Research methodology 101Research methodology 101
Research methodology 101
 
Cochrane reviews and guideline development: Is there anything new under the sun?
Cochrane reviews and guideline development: Is there anything new under the sun?Cochrane reviews and guideline development: Is there anything new under the sun?
Cochrane reviews and guideline development: Is there anything new under the sun?
 

More from Pierre Trudelle

More from Pierre Trudelle (20)

Lampierre jfk2011
Lampierre jfk2011Lampierre jfk2011
Lampierre jfk2011
 
Kerkour jfk2011
Kerkour jfk2011Kerkour jfk2011
Kerkour jfk2011
 
A100bisKerkour
A100bisKerkourA100bisKerkour
A100bisKerkour
 
Contal jfk2011
Contal jfk2011Contal jfk2011
Contal jfk2011
 
Messina jfk2011
Messina jfk2011Messina jfk2011
Messina jfk2011
 
Trudelle-Bleton jfk2011
Trudelle-Bleton jfk2011Trudelle-Bleton jfk2011
Trudelle-Bleton jfk2011
 
Trudelle jfk2011
Trudelle jfk2011Trudelle jfk2011
Trudelle jfk2011
 
Messina jfk2011
Messina jfk2011Messina jfk2011
Messina jfk2011
 
Ferrandez jfk2011
Ferrandez jfk2011Ferrandez jfk2011
Ferrandez jfk2011
 
Laurent jfk2011
Laurent jfk2011Laurent jfk2011
Laurent jfk2011
 
Regnaux jfk2011
Regnaux jfk2011Regnaux jfk2011
Regnaux jfk2011
 
Vaillant jfk2011
Vaillant jfk2011Vaillant jfk2011
Vaillant jfk2011
 
Tayabaly jfk2011
Tayabaly jfk2011Tayabaly jfk2011
Tayabaly jfk2011
 
Gain jfk2011
Gain jfk2011Gain jfk2011
Gain jfk2011
 
Messina jfk2011
Messina jfk2011Messina jfk2011
Messina jfk2011
 
Lasbouygues jfk2011
Lasbouygues jfk2011Lasbouygues jfk2011
Lasbouygues jfk2011
 
Vazeux jfk2011
Vazeux jfk2011Vazeux jfk2011
Vazeux jfk2011
 
Sansonnens jfk2011
Sansonnens jfk2011Sansonnens jfk2011
Sansonnens jfk2011
 
Stevenot jfk2011
Stevenot jfk2011Stevenot jfk2011
Stevenot jfk2011
 
Aswad jfk2011
Aswad jfk2011Aswad jfk2011
Aswad jfk2011
 

A Herbert

  • 1. WHEN AND HOW SHOULD NEW THERAPIES BECOME ROUTINE CLINICAL PRACTICE? Rob Herbert, Senior Research Fellow
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 14.
  • 15.
  • 16.

Editor's Notes

  1. The National Institutes of Health is funding the international “Esprit” study of IL-2 for people with more than 350 T-cells. This $43 million study is the most expensive clinical trial in history. It will enroll 4,000 participants at 210 research sites in 18 countries and follow them for up to 6 years. Again, all participants will receive antiviral therapy, and the treatment group will also receive IL-2.
  2. … however implementation of randomised trials is inconsistent. Sometimes trials are conducted early in the process of introducing a new therapy, but sometimes new therapies become well established before they are subject to randomised trials.