24° CORSO RESIDENZIALE DI AGGIORNAMENTO con il patrocinio dell’Associazione Italiana di Radioterapia Oncologica (AIRO) Moderna Radioterapia, Nuove Tecnologie e Ipofrazionamento della Dose La rivoluzione dell’introduzione del modello LQ nella pratica clinica

1. La rivoluzione dell’introduzione
del modello
LQ nella pratica clinica

4. Bentzen, Ph.D., D.Sc.
Departments of Human Oncology; Medical Physics; Biostatistics and Medical Informatics,

5. Gay et al 2009 Rad Onc 91, 369

6. The essential problem of the LQ model
stems from ignoring the reduction of
sublethal damage after the conversion to
lethal damage; therefore, the pool size of
the sublethal lesions that are available to
be converted to lethal lesions with further
irradiation is overestimated

7. LQ model tends to overestimate
the effectiveness of cell killing by a
single high dose.

8. Inversodelladoseletale50

9. Bentzen, Ph.D., D.Sc.
Departments of Human Oncology; Medical Physics; Biostatistics and Medical Informatics,