Directed evolution is a method used in protein engineering that mimics the process of natural selection to evolve proteins ornucleic acids toward a user-defined goal.

1. Find A Leader in Applying
Directed Evolution
Prepared and Compiled by Creative Biomart

2. Directed Evolution
Directed evolution is a method used in protein
engineering that mimics the process of natural
selection to evolve proteins ornucleic
acids toward a user-defined goal.

3. Technical Solution
• In vitro molecular evolution strategies are
widely regarded as the most efficient methods
for creating proteins and regulatory sequences
with improved or novel properties. Creative
Biomart GenePowerTM Directed Evolution
services cover a variety of different approaches
for creating genetic variants. Paired with
appropriate screening methods, our directed
evolution technologies can create the genetic
diversity you need to obtain proteins with the
characteristics you need.

4. Advantage
•Most service offerings do not require DNA template—
DNA is synthesized from your sequence information.
•Complete control over every important feature of the
library—Create rational diversity where it is likely to
have the most impact.
•Significantly reduced screening effort compared to
conventional mutagenesis methods.
•Generate variants that cannot be created using
conventional methods.
•Maximum sequence integrity in unmutated regions,
maximum variation where you want it, and maximum
insert size.
•Improved likelihood of obtaining useful variants.

5. About Creative Biomart
Creative Biomart is a leader in applying
directed molecular evolution to improve
healthcare by discovering, optimizing and
developing human biotherapeutics.

6. Contact
• Creative Biomart
• http://www.creativebiomart.net/Directed-Evolution.htm
• 45-16 Ramsey Road, Shirley, NY 11967, USA
TEL: 1-631-559-9269
EMAIL: info@creative-biomart.com
• St John's Innovation Centre, Cowley Road, Cambridge CB4
0WS, UK
TEL: 44-207-048-3343

7. Thank You
We understand the importance of convenient
and easy-to-use systems for high level
expression and sample purification. We invite
you to review our growing range of expression
systems resulting from our experience in
cloning, overexpression and purification.