Babycell is the umbilical cord blood stem cell banking service provided by RMS. Babycell services are available all across India through its vast spread bio-network of hospitals, medical doctors and collection centres. Babycell service briefly includes harvesting of the cord blood from the umbilical cord of the placenta at birth, isolation of the Haemotopoietic Stem Cells (HSCs), and cryopreservation for 21 years in RMS Stem Cell Bank for future transplantation of these stem cells into patient.
6. The magic of regeneration has always been seen in nature.
We humans are discovering its powers NOW!
Regeneration can be seen perfectly in sea cucumbers. Their bodies can grow up
to three feet long and if cut into pieces, each piece can REGROW into a new sea
cucumber.
The White-tailed deer can REGROW their antlers and this is the
most extreme example of regeneration!
7. Lizards have the ability to REGROW their tail within nine months.
The starfish have the ability to REGROW their arms and sometimes their
whole bodies. Even if the critter is down to one arm, as long as it has its
central nerve ring intact, it can grow into an entirely new starfish.
The human body has so much to offer, we are exploring its capacity to the best!
8. What are these magical cells?
“Basic unit of life”
Stem cells are the body's raw
material — from which all other
cells with specialized functions are
generated.
How amazing is it that life begins with a single cell!
9. Where do we find them?
• Umbilical Cord Blood
• Umbilical Cord Tissue
• Bone Marrow
• Peripheral Blood
• Other sources under research
• Dental Pulp
• Adipose Tissue (Fat)
• Embryo
10. Disease statistics
1. Worldwide, the annual number of new cases of childhood cancer exceeds
200,000 and more than 80% of these are from the developing world.
2. Every year around 32,000 children with Thalassemia are born in India
3. Approximately 8,000 cases (4,400 males and 3,820 females) of Hodgkin's
Lymphoma are detected per year . In India, 21% of all Hodgkins disease was seen
in children with a marked male female ratio of 5.5:1
4. Each year approximately 300,000 children are born with sickle cell anaemia or
one of its variants and nearly 80 per cent of these births occur in poor socio-
economic countries
References:
1. http://www.indianjcancer.com/article.asp?issn=0019-509X;year=2009;volume=46;issue=4;spage=264;epage=273;aulast=Arora
2. http://jcnh.in/download/isse1/3.%20Amrita%20Panja.pdf
3. http://www.lymphomainfo.net/hodgkins/incidence.html
4. Piel FB, Patil AP, Howes RE, Nyangiri OA, Gething PW, Williams TN, et al. Global distribution of the sickle cell gene and geographical confirmation of the malaria
hypothesis. Nat Commun. 2010;1:104.[PMC free article] [PubMed]
11. PM Narendra Modi speaking about stem cells
• PM Narendra Modi visited the Stem Cell Research facility at
Japan in Sep 2014.
• He had a conversation with Shinya Yamanaka, Japan’s stem
cell pioneer and a 2012 Nobel Prize winner
• Spoke about concerns regarding the prevalence of sickle
cell anaemia among Indians
• Along with Shinya Yamanaka, Hon PM Narendra Modi
discussed about remedy for sickle cell anaemia through
stem cells
Indian PM Narendra Modi (R) speaking to
Japanese Nobel Prize-winning stem cell
researcher Shinya Yamanaka (L)
Click here to read more
12. Umbilical Cord Stem Cells and upcoming uses
• Acquired Hearing Loss : 63 million people in India suffer of acquired hearing loss
• Cerebral Palsy : In India, it is estimated at around 3 cases per 1000 live births.
• Congenital Heart Disease : Every year 78,000 infants born with congenital heart disease in India die
• Juvenile Diabetes : India is home to an estimated 97,700 children with Type 1Diabetes Mellitus
• Pediatric Stroke : Prevalence of stroke in India range from 44 to 843 per 100,000 population.
• Traumatic Brain Injury : 1.5 – 2million persons are injured and 1million die every year in India.
• Autism : India is home to about 10million people with autism.
In a landmark decision, approval given by U.S. FDA for the following diseases.
Approvals expected for commercial use as early as 2017
13. Cord blood stem cells and future use
Acquired hearing loss
Autism
Paediatric stroke Traumatic brain injury
14. Umbilical Cord Blood Umbilical Cord Tissue
• Tissue of the umbilical cord (not the blood inside it)
• Contains Mesenchymal Stem Cells. These have the ability
to regenerate tissue, nerve cells and damaged organs.
• Repairs bone, cartilage and connective tissue. Future
treatment may include spinal cord injuries and strokes
• First clinical trial - 1995
• Is now being researched and explored with over 200
clinical trials under way (globally)
• Blood that flows in the umbilical cord and placenta
• Contains Hematopoietic Stem Cells. These have the
ability to regenerate all types of blood cells.
• Treats blood related diseases and cancers such as
leukemia, anemia, thalassemia and autoimmune
disorders.
• First case - 1988
• Is now being used to treat over 80 blood related diseases
with 30,000 successful transplants (globally)
15. Why should we preserve
Umbilical Cord Stem Cells when
other sources are available?
16. • Cell Concentration is almost 10%-20% higher
than other sources.
• Faster differentiation and multiplication
potential since they are immature cells unlike
adult stem cells from other sources.
• Less prone to rejection as they have less
developed features.
• Preserved only for your family’s use and no
queuing to find a matching donor.
• Requires only a 4/6 match
Case study: Stanford professor dies after long search for bone marrow donor
17. Cord Blood Transplantation Success Story
The first successful cord blood transplant
was done on Matthew farrow
Click here to read the success story
Obstetrician from UK with leukemia is helped
by cord blood transplant
David Hall, 66, from UK, spent 33 years delivering
babies and clamping umbilical cords, which
became the source of his second chance at life.
Click here to read the success story
In 1988, Matthew, a 6 year old then, was diagnosed
of Fanconi Anaemia. Today, 26 years later, Matthew
Farrow is alive and the lucky recipient of the world’s
first cord blood transplant.
18. India's first Cord Blood transplantation was for Acute Lymphoblastic Leukemia (ALL) at Tata
Memorial Hospital in 1996, followed by many more…
A child from Mumbai, Thane becomes the first
patient in India to be cured of thalassemia in
2008
Rishi Bhanushali, a thalassemic major
child from Kutch, Gujarat, gets treated
in 2009
21. Transplant Specialist Panel Sr.no. Transplant specialists Hospital
1. Dr Sandip Shah Gujarat Cancer Research Institute, Ahmedabad
2. Dr. Revathi Raj Apollo Hospital, Chennai
3. Dr. Vijay Ramanan Ruby Hall Clinic, Pune
Dr. Adwaita A Gore
1. Prince Aly Khan Hospital, Mazgaon
4 2. Kohinoor Hospital, Kurla
5 Dr. Niranjan Rathod Kokilaben Hospital, Mumbai
6 Dr. Tapan Saikia Kokilaben Hospital, Mumbai
Dr. Suparno Chakrabarti Dharamshila Hospital, Delhi
7
8 Dr. Rahul Naithani Max Super speciality Hospital, New Delhi
9 Dr. Neeraj Sidharthan Amrita Institute of Medical Sciences, Kerala
Dr. Rahul Bhargava
10 Artemis Hospital, Gurgaon
11 Dr. Mahesh Rajashekaraiah BGS Global Hospital, Bangalore
Dr. Indranil Ghosh
12 Apollo Hospital, Kolkata
Dr. Gaurav Kharya
13 BLK Super Speciality Hospital, New Delhi
Dr. Suresth Advani14 Jaslok Hospital
Dr. Dharma Choudhary BLK Super Speciality Hospital, New Delhi
15
Dr. Ashish Dixit
16 Manipal Hospital, Bangalore
Dr.Kannan Subramanian17 Sahaydri Hospital, Pune
Dr Mammen Chandy
18 Tata Medical Centre, Kolkata
Dr. Sunil Parekh
19 Bombay Hospital, Mumbai
20 Dr.Abhay A. Bhave Lilavati Hospital and Research Centre
Dr. Vijay Ramanan,
Pune
“Stem cells can be used to treat
80 blood disorders and many
more in near future. Babycell is
an institution which you can
approach for your needs for stem
cell purpose’’
22. Doctors Speak
Past president: Federation of Obstetric and Gynaecological
Societies of India (FOGSI)
“Stem cell preservation is a smart, affordable, and simple way of
ensuring a good life and hope of saving your loved ones from health
related problems in future. Umbilical Cord Blood Banking is the most
optimum solution available to mankind today!”
Dr. Suchitra Pandit, Mumbai
Dr. Nayna Patel, Anand
23. Doctor speaks
“Babycell services are
excellent. They come on
time for deliveries. Stem cell
banking is very useful for
your future family health.”
Dr. G. Sudha Rani,
Hyderabad
“Best services are provided
by your team and also
patients are satisfied.”
Dr. B. Usha Rani,
Hyderabad
24.
25. Meet and Receive
• Fill up the health questionnaire,
personal details, understand the
Client Benefits and sign up!
• Receive Collection Kit and follow
instructions mentioned on it.
• On the day of delivery, carry kit and
call us to arrange the collection and
transportation.
26. Collect and Transport
• In case you have opted for our phlebotomist, they
will collect the sample and hand over to our logistics
partner.
• A special cold chain arrangement with TNT is
available 24 x 7 x 365 which handles our biological
samples
• Temperature validated kits for 72 hours
• No X-Ray Certificate
Data logger report
Data logger
27. Preserve and Retrieve
Strategically located CPC in non-seismic, flood-proof and non-
polluting environment
On-site engineering team monitors sample to ensure
temperature, humidity and pressure maintenance 24 x 7 x 365
Adherence to strict guidelines as per GMP, GCP, GLP, FDA, DCGI
and ISO; entry permissible only to authorized personnel
Stainless steel construction, fire proof storage area, systems
designed to sustain power cut
Global shipment to any doctor centre using cryoshipperTake a tour of our Cell Processing
CentreTM right now!
View certificates
29. Cord Tissue Processing
Cord Collection Kit
Umbilical Cord is processed and
segmented into small pieces.
Cells obtained from
enzymatic digestion of
Umbilical Cord Tissue are
transferred into several
cryovials
The cells are frozen in the
controlled-rate freezer, where
the temperature is lowered
gradually to optimize
preservation of stem cells.
After the controlled-rate freezing
process, the cryovials are
transferred for long term
cryopreservation at -196°C.
Isolation of UCT to give Whole Cell
Population (WCP) including MSCs,
Epithelial cells and fibroblasts
30. Exclusive Tests • Total nucleated cell count
• Total mononuclear cell count
• Total CD 34+ stem cell count
• CD 34+ Stem cell viability
• Sterility testing
• Colony forming unit (CFU) test for stem cells
• Blood grouping
• Infectious disease testing (HIV 1&2, HBsAg,
Anti HBC, HCV, HTLV 1&2, CMVIgG, CMVIgM,
Syphilis and malaria)
• Maternal Blood Test
• Tests for Cord Tissue – Cell count, cell viability,
sterility testing and quality – visual check
(Babycell is the only cord blood bank that performs this test at the time of
preservation. All accreditation authorities endorse CFU and strongly recommend
it at the time of preservation and not retrieval)
34. ‘’Babycell Processing Technology
is superior to any other banks &
the value added services like
CFU, HLA Typing, and
personalized ANC/PNC sessions
are second to none. Thanks
Babycell!!’’
Speaking about CFU and
HLA
Speaking about their
visit to Babycell CPCTM Speaking about Logistics
Speaking about New
born screening
Mr. and Mrs. Bhanushali (Mumbai) Mr. and Mrs. Mulchandani (Mumbai)
One of the most important factors
to choose Babycell was that their
storage facility is close to our city
and they had the confidence to
invite us to visit the lab to see their
operations if we wished. We
availed of their services for both
our children and have been
extremely satisfied till date!
Mr. and Mrs. Saini (Kota)
“The experience that we had with
Babycell, at every phase was
superior, like the presentation,
coordination done at the time of
collection and post sales services.
They have worked extremely hard
to help us to know the minutest
details of the concept.”
Mr. and Mrs. Anand
“One of the best things about
Babycell is their post sales
services like the ‘New born
screening test’ that they had
provided for our new born
babies, Aamya and Avin. The
online post-natal sessions for
mothers were helpful too. We
can completely rely on Babycell
for any advice in the future!!
Thank you Babycell.”
Client testimonials
35. “In our case the delivery
happened 5 weeks prior to the
predicted date! Babycell
exceeded our expectations, with
the staff (Rajeshwari) immediately
arriving at the hospital and
staying all night waiting for the
delivery. She left only after she
had completed the collection of
the cord. We are extremely happy
and grateful to Babycell.”
Speaking about on time
collection
Speaking about easy
plans
Speaking about entire
process
“During the birth of my first child, I
wasn’t very sure about the benefits of
stem cell banking, but during my
second child’s birth, I had enough
wisdom and the awareness of the
benefits of the banking. When I
bought this from Babycell, in my view
at that point in time, the offer from
Babycell was best in comparison to
the other companies.
Babycell is reputed and
professional and most important
part for middle class people like
us. It was affordable and the
instalment scheme helped us
preserve the baby’s stem cells as
per our needs.
Staying away from India and
delivering baby was not an easy
decision, whereas collecting
stem cell and storing back in
India was only in our dreams.
With the Babycell overall service
from the case owner, supervisor,
logistics shipment, delivery,
storing and testing cell the
entire process were Just in time
(JIT) process 100%.
Client testimonials
Mr. and Mrs. Rajaram Kannan
(Hyderabad)
Mrs. Sejal Bhavesh Malde, Thane Mr & Mrs. Sajid Golandaz,
Mumbai
Mr. & Mrs. Bilwa
Speaking about Babycell
vis a vis competition
37. Sibling Program
Babycell’s Sibling Program caters to expecting parents
who have a child that is diagnosed with a treatable
haematological condition. If assessed to be curable with
haematopoietic stem cell transplant, then Babycell will
provide cord blood collection, processing and storage
completely free of cost for 5 years for the upcoming baby
along with financial support up to 5Lacs
So far we have registered 15+ clients under our Sibling Program
38. Donation to CARF
Babycell has extended a helping hand to the cancer
patients by contributing towards the cancer aid
and research foundation through every enrolment.
39. Go Green initiative
This was an initiative with Mumbai
Obstetric and Gynecology Society to make a
positive contribution to the environment
starting at our facility in Lonavla.
40. Spreading a smile
The objective of this program is to restore
the normal development and active life of
children born with cleft lip & palate. The
CSR wing of RMS started to treat children
with our innovative Tissue Engineered
Collagen product free of cost.
https://www.youtube.com/watch?v=74s35
emlwRU
42. Indications:
• Trauma
• Disease Condition
• Injury
Caused to the Cartilage in Joints
• Knee
• Ankle
• Shoulder
Prevents the progress to Osteoarthritis
Defected Cartilage
CHONDRON™
Implantation
Complete
Regeneration of
Natural Cartilage
Regrow Your Cells. Rebuild Your Life.
Cell Therapy – Cartilage Implantation
Click here to view Chondron video
43. Case 1 (30/M, OCD)
Case 2 (25/M, OCD)
Case 3 (41/F, Osteochondral Injury)
Relook ArthroscopyIntra-op DefectPre-op MRI
Intra-op Defect
Chondron Implant set Relook Arthroscopy
Post op recoveryChondron Implant setCartilage Defect
Case study:
44. Indications:
• Avascular Necrosis
• Non-union Fractures
• Fibrous Displasia
• Bone Cyst/ Cavity
• Facial/ Oral Bone Gaps and Defects
Natural Alternate to Total Hip Replacement and Total Knee
Replacement
Bone Gap
OSSRON™
Implantation
Complete
Regeneration of
Natural Bone
Regrow Your Cells. Rebuild Your Life.
Cell Therapy – Bone Implantation
Click here to view the Ossron video
45. Case 1 (58/F, Non-union)
Case 2 (37/M, AVN)
Post-op MRI
Intra-op Defect
Pre-op MRI
Pre-op MRI Post-op MRI
47. Cell Therapy – Skin Regeneration
Regrow Your Cells. Rebuild Your Life.
Burns
THERAFORM™
Application
Complete
Regeneration of
Natural Skin
Diabetic Foot Ulcers
Maxillofacial Cleft palate (roof of mouth)- Birth defect
48. Services
• Cord Blood Collection
• Cord Tissue Collection
• Colony unit forming assay (CFU)
• HLA testing
• Testing, Processing, Preservation and Retrieval
for 21 years
• Global Shipment
• Transplant Specialist
• New Born Screening
• Father’s Wellness Check Up
• Mummy & Tummy (Pre and Post Natal Care
Sessions)
49. Babycell’s Additional Support
• Regrow Health Cover (clause 8.1)
• Loyalty Privilege (clause 8.2)
• Quality Assurance (clause 8.3)
• Philanthropy Programme (clause 8.4)
• Life Cover (clause 8.10)
• Right of Money Back (clause 8.11)
• Sibling Program (clause 8.5)
• Stem cell expansion as prescribed by
transplant physician (clause 8.8)
• Collect and transport assist (clause 8.6)
• Stem cell xpert programme (clause 8.9)
• Tailor-made Package
50. For those who want more!
Babycell™ Biocord
Haemoglobinopathy test
HLA typing
HLA cross matching
Full body screening
New Born Screening
Colony Forming Unit
Gift hamper
Data Logger facility
Maternity photo shoot
Home session for ante-natal care
Home session for post natal care
Quality Assurance upto 30 Lacs
Philanthropy program upto 30 Lacs
One Treatment Free under Regrow Health Cover
51. Thank You
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