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premium neuromodulation
Premium Neuromodulation
TM
© 2019 BBB inc. All Rights Reserved.
Neuromodulation −dubbed as “Brain Stimulation”− is a technique that improves the function of
certain parts of a brain by applying force such as magnetic field or direct current to the area
where brain function is stagnated. It has been clinically used to treat patients and enhance brain’s
ability.
In 2019, BBB presents neurogear™, a noble neuromodulation device, which activates brain nerve
cells without being physically bothered thanks to stimulation-free fine magnetic field. Selecting
target of activation is possible by the QUADRUPOLE electromagnet structure, the creation of
exclusive technology behind neurogear™. It features various functions from emotion control,
concentration enhancement to cognitive functioning.
StimulateWithout Stimulation
Technology Description :
Effect of Magnetic Field
© 2019 BBB inc. All Rights Reserved.
Neuroactivation Principle:
When a magnetic field is applied to the brain, an electric current or electric field is generated in the
brain by electromagnetic induction and stimulates neurons. When a current is applied to the
stimulating coil on the scalp, a variable magnetic field is produced. As a result, a reverse eddy
current or an electric field is induced to stimulate nerve cells and an action potential is generated.
A GentleMagneticPulse :
The neurogear™ uses fine magnetic pulse to stimulate a brain without physical stimulation. The
device synchronizes a brain with alpha wave of 10Hz, an ideal frequency that appears in a
harmonious brain, which enhances concentration, wakefulness, learning ability, and invites you to a
calm mind.
Technology Description :
Quadrupole electromagnetic structure
8 channels of
electromagnet
© 2019 BBB inc. All Rights Reserved.
Quadrupole electromagneticstructure :
The neurogear™ has implemented a technique that can safely stimulate deep brain in a non-
invasive way rather than a surgical procedure. The round headgear has eight electromagnetics in
total, two in four directions. Through continuously changing the magnetism of each electromagnet
to N and S pole, it builds up magnetic field stimuli on the specific region. The result is activated
nerve cells on the target. Stimulating deep brain is possible by operating eight electromagnetics at
the same time so that meaningful stimuli are loaded on the deep brain.
DBS :
Deep Brain Stimulation (DBS) is a surgical treatment that transplants a neurostimulator or brain
pacemaker into the brain. It is a type of electrotherapy that uses an electrical stimulator to send
electrical stimulation to a specific area of the brain. The FDA has approved DBS for the treatment of
hysterics, Parkinson's disease, and dystonia. It is used to alleviate a tremor in patients with
Parkinson's disease that cannot be controlled with drugs.
Description :
5 Modes, 5 Neuroscience
"Our brain circuits are an interconnected
network like an environment, and they
are also very vulnerable ecosystems at
times. That’s why depression matters.”
- Alex Korb , < The Upward Spiral>
© 2019 BBB inc. All Rights Reserved.
Broken balance between right and left brain can lead to depression, anxiety, and emotional
instability. Unstable brain degrades the brain center which controls emotions by disturbing
exchange of electric signals and fails temporal lobe which associates with cognitive regulation.
1. De-Stress Mode
Description :
5 Modes, 5 Neuroscience
The neurogear™ introduces De-Stress Mode to restore the
balance between right and left brain. The mode changes N
and S pole of four electromagnetics (two in the left and right,
respectively) out of eight. Repeating the process concentrates
electrical activities on “central part of the temporal lobes.”
Amygdala, thalamus and hippocampus are activated, and the
brain balance is recovered. It is suitable for use in psychiatric
clinics and psychotherapy centers.
2. Relax Mode
The awake brain has more than 10hz of brainwave, while the frequency decreases to 5hz during
the sleep. All areas of the brain have this in common, and the cycle repeats every 1 to 2 hours.
In Relax Mode, the magnetism of all 8 electromagnets repeatedly
goes back and forth between N and S pole, and magnetic field
stimulation is transmitted to the entire brain. At this time, the
magnetic field resonates with 6 to 10Hz oscillation − which is
similar to sleeping brain wave −, so that the brain can rest as if it
sleeps.
● Exclusive fitness center ● Company welfare
© 2019 BBB inc. All Rights Reserved.
● Psychiatric clinic ● Psychotherapy center
The frontal lobe is responsible for human's most complex and higher-order thinking skills such as
judgment, planning, and logic skill. Impaired frontal lobe reduces impulse control, memory and
planning skill. In severe cases, it can lead to ADHD or Alzheimer's disease.
3. Focus Mode
Description :
5 Modes, 5 Neuroscience
In Focus Mode, the magnetism of two electromagnets on the
forehead repeatedly changes its N and S pole to concentrate
significant stimuli on target area − frontal lobe −. Through this
process, activated frontal nerve cells elevate judgement,
computing power and ability to control behavior.
4. Memory Mode
Among frontal lobes, the left frontal lobe is closely involved in long-term memory formation and
memory retrieval. Sluggish activity in this part brings a loss in memory recovery and retention,
which may result in various forms of memory impairment.
In Memory Mode, front and left electromagnets operate by N and
S pole, respectively, and magnetic field is concentrated on the “left
frontal lobe.” Through this process, the left frontal lobe
responsible for memory can be activated to improve memory and
cognitive ability.
● Senior community ● Nursing homes for senior citizens
● Dementia prevention center
© 2019 BBB inc. All Rights Reserved.
● Psychiatric clinic ● Psychotherapy center
Creativity is demonstrated when strong connection has made between frontal lobe (in charge of
higher cognitive function) and perceptual domain. neurogear™ improves creative thinking which
incorporates audiovisual sense by enhancing connectivity of temporal lobe (responsible for the
hearing) and occipital lobe (responsible for the vision).
5. Boost Mode
Description :
5 Modes, 5 Neuroscience
In Boost Mode, all eight electromagnets are activated and the
connectivity among frontal-temporal-occipital lobes is boosted,
facilitating synesthesia thinking in which senses are integrated,
and expressing creativity. Boost your artistic creativity, go
further in mathematics and science, and improve your
problem-solving ability and insights by thinking outside the
box.
● Creativity training center ● Company welfare
© 2019 BBB inc. All Rights Reserved.
© 2019 BBB inc. All Rights Reserved.
“Depression ismiscommunication between brain circuits.”
- Alex Korb , < The Upward Spiral>
●
●
●
●
●
headset cradle
headset
control touch panel
electro-magnet 4-way, 8channel ledhead strap
● ● ● ●
● ●
●
●
© 2019 BBB inc. All Rights Reserved.
Type
Electro-Magnetic Stimulation
1 Headset, 1 Controller, 1 Cable
Dimensions
290(w) X 340(d) X 180(h) mm
Headset + Controller
Weights
Headset 1.7 kg, Controller 1.25 kg
Control System
Android OS 7.0
Amplitude
0.1 - 10mT
Range of frequency
1-30Hz
Specification :
© 2019 BBB inc. All Rights Reserved.
Neurogear brochure
TM
premium neuromodulation for hospital use
FOR HOSPITAL USE
FOR PROFESSIONAL USE :
neurogear pro™ is a medical device for the treatment of depression, anxiety disorder,
obsessive-compulsive disorder, ADHD, and cognitive impairment and dementia of the elderly.
The healthcare professionals can use the Expert Mode to set the required treatment value for
the patient. Patients can be treated in comfort because no auditory or physical stimulation is
generated during operation.
Noise-Free & Stimulation-Free – Mount safe and non-invasive therapy
COMINGSOON :
BBB aims to launch neurogear™ in 2019 and unveil neurogear pro™ in 2020 after acquiring
certification for medical devices. It is under clinical trials on the “Effective treatment for
depression" at California Institute of Technology (Caltech), Chapman University, and St. Mary’s
hospital of the Catholic University in Korea.
EXPERT MODE :
Healthcare providers can choose among following four settings according to the type of
treatment for patients.
Duration . Frequency . Amplitude(8 Electromagnet) . Orientation (8 Electromagnet)
neurogear™ offer you two options. neurogear™ for everyone (both for medical and non-
medical personnel) and neurogear pro™ for hospital use at the discretion of healthcare
providers. neurogear™ provides five modes for you to choose from, and neurogear pro™
features exclusive “Expert Mode.”
TM
© 2019 BBB inc. All Rights Reserved.
What is the difference between <neurogear> and <neurogear pro> ?
<neurogear pro> is a medical device used for treating patients in hospital under the judgment of
healthcare providers. <neurogear>, a light version of <neurogear pro>, offers manual modes for
everyone such as stress relief, mood control, improvement of cognitive function, enhancement of
creativity, etc.
Where can I use <neurogear>?
Since <neurogear> is made not only for healthcare providers but also for everyone, you can use it for
various purposes in diverse places. You can use it in a company welfare program for workers to take a
break, relieve the stress of daily life, and get back to work being more focused. You can have
<neurogear> at cram schools or other educational institutions to advance students' learning ability. It
can also be used in social welfare facilities and nursing homes to improve the cognitive abilities of the
elderly.
What are the technical advantages of <neurogear> and <neurogear pro> as a non-invasive
neuromodulation device?
There are a variety of non-invasive neuromodulation devices in the market. After 20 years of active
research, various products have been developed. Non-invasive neuromodulation using magnetic field,
current, and ultrasonic wave are widely used in clinical trials. <neurogear> and <neurogear pro> have
been developed using clinically-proven safe magnetic field technology and are distinguished from other
devices with its small and light body, and multiple coils for maximum effect. In addition, there is no
auditory or physical stimulation so that you can stay comfortable during operation.
How does the direct magnetic field in the head affect the body?
The magnetic field strength used by <neurogear> and <neurogear pro> is similar to magnetic field
generated by home appliance such as headphones and refrigerators. It is harmless to human bodies if
you keep the basic use time of 20 minutes, once a day.
Why is it effective even though it is much weaker than clinical TMS?
The NASA irradiated micro-magnetic field directly to nerve cells and demonstrated cell activation in early
2000. Since then, many micro-field studies have reported effects on nerve cell activation, cognitive
function improvement, and depression mitigation.
What is the technical difference with tDCS?
<neurogear> and <neurogear pro> can expect high signal transmittance without physically bothering
users because they use magnetic field. The transcranial direct current stimulation (tDCS) flows current to
the skin. In order to make the current flow, it is inevitable to use a sponge soaked in saline solution to
reduce the skin resistance. User may feel discomfort, irritation, and experience side effects such as skin
burn.
Is <neurogear Pro>, a medical device for hospital, used in conjunction with medication?
<neurogear pro> can be effectively used for treatment of depression, especially Treatment-Resistant
Depression (TRD), which is resistant to drugs. Previous clinical trials have shown that depression is
improved by 10% or more in 50 TRD patients after being treated with <neurogear pro>, five times per
week for five weeks. Since the side effects are lower than those of drug treatment, we plan to extend the
scope of use for patients with depression who are treated with medication through further clinical trials.
FAQ:
Does <neurogear> and <neurogear pro> have immediate effect? Can I expect a cumulative effect?
There is immediate improvement, but if you continue to use for more than five weeks, 10-30% of
improvement is expected depending on the patient. In cognitive function test on five participants,
conducted by Brain Imaging Center at the California Institute of Technology, has shown that error rate
reduced by over 30%.
Can I use it for teenagers?
No side effect was reported in a clinical study of 1,034 adolescents aged between 11 and 18 years.
Neuromodulation using magnetic field is more suitable for pregnant women and adolescents who are
reluctant to or cannot use medication.
What is the technical principle behind Focus Mode (increasing concentration) of <neurogear>?
Unlike conventional neurofeedback products that synchronize the whole brain with sound and light,
<neurogear> uses a magnetic field of specific frequency to selectively activate areas related to cognitive
function and learning ability. The optional activation maximizes the effect while minimizing unnecessary
irritation.
Does Memory Mode (reinforcing cognitive function) of <neurogear> and <neurogear pro> can
improve impaired functions? Or does it have preventive effect?
<neurogear> and <neurogear pro> improve damaged cognitive function. You can expect 2-5% of
immediate improvement in cognitive function, and the figure rises to 10% if you continue to use more
than five weeks. A long-term clinical study of 307 patients confirmed that the effect lasts for up to 16
weeks after 4-6 weeks of use. BBB is currently conducting clinical trials with leading research institutes
on how <neurogear> and <neurogear Pro> enhance cognitive abilities.
Were there any techniques to stimulate deep brain in a non-invasive way?
Among existing TMS, there is Deep TMS. It is a helmet type that uses a coil which wraps around the
entire head to target the deep brain. Meanwhile, <neurogear> and <neurogear pro> use micro-magnetic
field and have small and light body to mitigate psychological burden of users.
To which diseases deep brain stimulation can be applied to in clinical trials?
Deep Brain Stimulation (DBS) is mainly used for patients having impaired deep brain cause by
Parkinson's disease or dementia. DBS is a surgical treatment that transplants a neurostimulator or brain
pacemaker into the brain. It is a type of electrotherapy that uses the implant to send electrical
stimulation to specific area of the brain. The FDA has approved DBS for the treatment of hand tremor,
Parkinson's disease and dystonia. The treatment is used to alleviate tremor in patients with Parkinson's
disease that cannot be controlled with medication.
Can’t I use existing TMS to stimulate deep brain?
TMS is designed to stimulate only one part of a brain with a single coil. <neurogear> and <neurogear
pro> use multiple TMS coils to stimulate deep brain. BBB is currently pending a patent on coil placement.
When <neurogear pro> be on the market?
In early 2020, we’ll begin with acquiring certification on depression treatment and extend the area step
by step to improvement of dementia, etc.
What is the strong point of <neurogear> and <neurogear pro> in a word?
It’s safe to use with low risk of side effects, easy to use intuitively, affordably priced compared to existing
TMS, and has no physical stimulation so that users can be comfortably treated.
FAQ:
2019. 04 (to do) Launch neurogearTM in US
2018. 10 Raised $15 million in Series B round
2018. 09 Selected as a National Project Supervision Institution “Bio Big-Data”
2017. 11 Launched elemarkTM dual check in Korea
2017. 08 Signed OEM contract with GenBody Inc. for supply of rapid test readers
for arboviruses and DOA
2017. 06 Signed MOU with Korea University Guro Hospital to develop next-generation
immunodiagnostic kit for cancer, myocardial infarction, and chronic disease
2017. 06 Signed MOU with Pusan University to construct infrastructure to commercialize research
2017. 04 Signed OEM contract with Philosys Inc. for supply of glucometers for hospital use
2016. 08 Signed agreement with KT for use of elemarkTM
2016. 08 Raised $5 million in Series A round
2016. 02 Signed strategic MOU with NOOM inc. targeting the mobile healthcare market
2015. 10 Winner of Zhongguancun Innoway “2015 Demo The World” in Smart Hardware Sector
2015. 08 Established regional office at NASA Ames Research Center, Silicon Valley, U.S.A.
2015. 05 Tech-In-Asia Award Winner @beGlobal Seoul 2015
2015. 04 Signed OEM contract with GreenCross MS for supply of in-vitro diagnostic devices
for hospitals
2015. 01 Joined HAX Batch 6 program
(HAX, Hardware startup accelerator based in Silicon Valley and Shenzhen)
2014. 10 Founded headquarters in Korea
About company:
© 2019 BBB inc. All Rights Reserved.
© 2019 BBB inc. All Rights Reserved.
© 2019 BBB inc. All Rights Reserved.
Business Contact
KOREA : Taebom Kim taebeom.k@bbbtech.com
USA : Ph D. Kyongsik Yun kyongsik@bbbtech.com
PR Contact
dike301@bbbtech.com
Company Website
bbbtech.com
Seoul Office
14F, 26, Samseong-ro 85-gil, Gangnam-gu,
Seoul, Republic of Korea
© 2019 BBB inc. All Rights Reserved.
TM
© 2019 BBB inc. All Rights Reserved.
© 2019 BBB inc. All Rights Reserved.

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Neurogear brochure

  • 2. Premium Neuromodulation TM © 2019 BBB inc. All Rights Reserved. Neuromodulation −dubbed as “Brain Stimulation”− is a technique that improves the function of certain parts of a brain by applying force such as magnetic field or direct current to the area where brain function is stagnated. It has been clinically used to treat patients and enhance brain’s ability. In 2019, BBB presents neurogear™, a noble neuromodulation device, which activates brain nerve cells without being physically bothered thanks to stimulation-free fine magnetic field. Selecting target of activation is possible by the QUADRUPOLE electromagnet structure, the creation of exclusive technology behind neurogear™. It features various functions from emotion control, concentration enhancement to cognitive functioning. StimulateWithout Stimulation
  • 3. Technology Description : Effect of Magnetic Field © 2019 BBB inc. All Rights Reserved. Neuroactivation Principle: When a magnetic field is applied to the brain, an electric current or electric field is generated in the brain by electromagnetic induction and stimulates neurons. When a current is applied to the stimulating coil on the scalp, a variable magnetic field is produced. As a result, a reverse eddy current or an electric field is induced to stimulate nerve cells and an action potential is generated. A GentleMagneticPulse : The neurogear™ uses fine magnetic pulse to stimulate a brain without physical stimulation. The device synchronizes a brain with alpha wave of 10Hz, an ideal frequency that appears in a harmonious brain, which enhances concentration, wakefulness, learning ability, and invites you to a calm mind.
  • 4. Technology Description : Quadrupole electromagnetic structure 8 channels of electromagnet © 2019 BBB inc. All Rights Reserved. Quadrupole electromagneticstructure : The neurogear™ has implemented a technique that can safely stimulate deep brain in a non- invasive way rather than a surgical procedure. The round headgear has eight electromagnetics in total, two in four directions. Through continuously changing the magnetism of each electromagnet to N and S pole, it builds up magnetic field stimuli on the specific region. The result is activated nerve cells on the target. Stimulating deep brain is possible by operating eight electromagnetics at the same time so that meaningful stimuli are loaded on the deep brain. DBS : Deep Brain Stimulation (DBS) is a surgical treatment that transplants a neurostimulator or brain pacemaker into the brain. It is a type of electrotherapy that uses an electrical stimulator to send electrical stimulation to a specific area of the brain. The FDA has approved DBS for the treatment of hysterics, Parkinson's disease, and dystonia. It is used to alleviate a tremor in patients with Parkinson's disease that cannot be controlled with drugs.
  • 5. Description : 5 Modes, 5 Neuroscience "Our brain circuits are an interconnected network like an environment, and they are also very vulnerable ecosystems at times. That’s why depression matters.” - Alex Korb , < The Upward Spiral> © 2019 BBB inc. All Rights Reserved.
  • 6. Broken balance between right and left brain can lead to depression, anxiety, and emotional instability. Unstable brain degrades the brain center which controls emotions by disturbing exchange of electric signals and fails temporal lobe which associates with cognitive regulation. 1. De-Stress Mode Description : 5 Modes, 5 Neuroscience The neurogear™ introduces De-Stress Mode to restore the balance between right and left brain. The mode changes N and S pole of four electromagnetics (two in the left and right, respectively) out of eight. Repeating the process concentrates electrical activities on “central part of the temporal lobes.” Amygdala, thalamus and hippocampus are activated, and the brain balance is recovered. It is suitable for use in psychiatric clinics and psychotherapy centers. 2. Relax Mode The awake brain has more than 10hz of brainwave, while the frequency decreases to 5hz during the sleep. All areas of the brain have this in common, and the cycle repeats every 1 to 2 hours. In Relax Mode, the magnetism of all 8 electromagnets repeatedly goes back and forth between N and S pole, and magnetic field stimulation is transmitted to the entire brain. At this time, the magnetic field resonates with 6 to 10Hz oscillation − which is similar to sleeping brain wave −, so that the brain can rest as if it sleeps. ● Exclusive fitness center ● Company welfare © 2019 BBB inc. All Rights Reserved. ● Psychiatric clinic ● Psychotherapy center
  • 7. The frontal lobe is responsible for human's most complex and higher-order thinking skills such as judgment, planning, and logic skill. Impaired frontal lobe reduces impulse control, memory and planning skill. In severe cases, it can lead to ADHD or Alzheimer's disease. 3. Focus Mode Description : 5 Modes, 5 Neuroscience In Focus Mode, the magnetism of two electromagnets on the forehead repeatedly changes its N and S pole to concentrate significant stimuli on target area − frontal lobe −. Through this process, activated frontal nerve cells elevate judgement, computing power and ability to control behavior. 4. Memory Mode Among frontal lobes, the left frontal lobe is closely involved in long-term memory formation and memory retrieval. Sluggish activity in this part brings a loss in memory recovery and retention, which may result in various forms of memory impairment. In Memory Mode, front and left electromagnets operate by N and S pole, respectively, and magnetic field is concentrated on the “left frontal lobe.” Through this process, the left frontal lobe responsible for memory can be activated to improve memory and cognitive ability. ● Senior community ● Nursing homes for senior citizens ● Dementia prevention center © 2019 BBB inc. All Rights Reserved. ● Psychiatric clinic ● Psychotherapy center
  • 8. Creativity is demonstrated when strong connection has made between frontal lobe (in charge of higher cognitive function) and perceptual domain. neurogear™ improves creative thinking which incorporates audiovisual sense by enhancing connectivity of temporal lobe (responsible for the hearing) and occipital lobe (responsible for the vision). 5. Boost Mode Description : 5 Modes, 5 Neuroscience In Boost Mode, all eight electromagnets are activated and the connectivity among frontal-temporal-occipital lobes is boosted, facilitating synesthesia thinking in which senses are integrated, and expressing creativity. Boost your artistic creativity, go further in mathematics and science, and improve your problem-solving ability and insights by thinking outside the box. ● Creativity training center ● Company welfare © 2019 BBB inc. All Rights Reserved.
  • 9. © 2019 BBB inc. All Rights Reserved. “Depression ismiscommunication between brain circuits.” - Alex Korb , < The Upward Spiral>
  • 10. ● ● ● ● ● headset cradle headset control touch panel electro-magnet 4-way, 8channel ledhead strap ● ● ● ● ● ● ● ● © 2019 BBB inc. All Rights Reserved.
  • 11. Type Electro-Magnetic Stimulation 1 Headset, 1 Controller, 1 Cable Dimensions 290(w) X 340(d) X 180(h) mm Headset + Controller Weights Headset 1.7 kg, Controller 1.25 kg Control System Android OS 7.0 Amplitude 0.1 - 10mT Range of frequency 1-30Hz Specification : © 2019 BBB inc. All Rights Reserved.
  • 14. FOR HOSPITAL USE FOR PROFESSIONAL USE : neurogear pro™ is a medical device for the treatment of depression, anxiety disorder, obsessive-compulsive disorder, ADHD, and cognitive impairment and dementia of the elderly. The healthcare professionals can use the Expert Mode to set the required treatment value for the patient. Patients can be treated in comfort because no auditory or physical stimulation is generated during operation. Noise-Free & Stimulation-Free – Mount safe and non-invasive therapy COMINGSOON : BBB aims to launch neurogear™ in 2019 and unveil neurogear pro™ in 2020 after acquiring certification for medical devices. It is under clinical trials on the “Effective treatment for depression" at California Institute of Technology (Caltech), Chapman University, and St. Mary’s hospital of the Catholic University in Korea. EXPERT MODE : Healthcare providers can choose among following four settings according to the type of treatment for patients. Duration . Frequency . Amplitude(8 Electromagnet) . Orientation (8 Electromagnet) neurogear™ offer you two options. neurogear™ for everyone (both for medical and non- medical personnel) and neurogear pro™ for hospital use at the discretion of healthcare providers. neurogear™ provides five modes for you to choose from, and neurogear pro™ features exclusive “Expert Mode.” TM © 2019 BBB inc. All Rights Reserved.
  • 15. What is the difference between <neurogear> and <neurogear pro> ? <neurogear pro> is a medical device used for treating patients in hospital under the judgment of healthcare providers. <neurogear>, a light version of <neurogear pro>, offers manual modes for everyone such as stress relief, mood control, improvement of cognitive function, enhancement of creativity, etc. Where can I use <neurogear>? Since <neurogear> is made not only for healthcare providers but also for everyone, you can use it for various purposes in diverse places. You can use it in a company welfare program for workers to take a break, relieve the stress of daily life, and get back to work being more focused. You can have <neurogear> at cram schools or other educational institutions to advance students' learning ability. It can also be used in social welfare facilities and nursing homes to improve the cognitive abilities of the elderly. What are the technical advantages of <neurogear> and <neurogear pro> as a non-invasive neuromodulation device? There are a variety of non-invasive neuromodulation devices in the market. After 20 years of active research, various products have been developed. Non-invasive neuromodulation using magnetic field, current, and ultrasonic wave are widely used in clinical trials. <neurogear> and <neurogear pro> have been developed using clinically-proven safe magnetic field technology and are distinguished from other devices with its small and light body, and multiple coils for maximum effect. In addition, there is no auditory or physical stimulation so that you can stay comfortable during operation. How does the direct magnetic field in the head affect the body? The magnetic field strength used by <neurogear> and <neurogear pro> is similar to magnetic field generated by home appliance such as headphones and refrigerators. It is harmless to human bodies if you keep the basic use time of 20 minutes, once a day. Why is it effective even though it is much weaker than clinical TMS? The NASA irradiated micro-magnetic field directly to nerve cells and demonstrated cell activation in early 2000. Since then, many micro-field studies have reported effects on nerve cell activation, cognitive function improvement, and depression mitigation. What is the technical difference with tDCS? <neurogear> and <neurogear pro> can expect high signal transmittance without physically bothering users because they use magnetic field. The transcranial direct current stimulation (tDCS) flows current to the skin. In order to make the current flow, it is inevitable to use a sponge soaked in saline solution to reduce the skin resistance. User may feel discomfort, irritation, and experience side effects such as skin burn. Is <neurogear Pro>, a medical device for hospital, used in conjunction with medication? <neurogear pro> can be effectively used for treatment of depression, especially Treatment-Resistant Depression (TRD), which is resistant to drugs. Previous clinical trials have shown that depression is improved by 10% or more in 50 TRD patients after being treated with <neurogear pro>, five times per week for five weeks. Since the side effects are lower than those of drug treatment, we plan to extend the scope of use for patients with depression who are treated with medication through further clinical trials. FAQ:
  • 16. Does <neurogear> and <neurogear pro> have immediate effect? Can I expect a cumulative effect? There is immediate improvement, but if you continue to use for more than five weeks, 10-30% of improvement is expected depending on the patient. In cognitive function test on five participants, conducted by Brain Imaging Center at the California Institute of Technology, has shown that error rate reduced by over 30%. Can I use it for teenagers? No side effect was reported in a clinical study of 1,034 adolescents aged between 11 and 18 years. Neuromodulation using magnetic field is more suitable for pregnant women and adolescents who are reluctant to or cannot use medication. What is the technical principle behind Focus Mode (increasing concentration) of <neurogear>? Unlike conventional neurofeedback products that synchronize the whole brain with sound and light, <neurogear> uses a magnetic field of specific frequency to selectively activate areas related to cognitive function and learning ability. The optional activation maximizes the effect while minimizing unnecessary irritation. Does Memory Mode (reinforcing cognitive function) of <neurogear> and <neurogear pro> can improve impaired functions? Or does it have preventive effect? <neurogear> and <neurogear pro> improve damaged cognitive function. You can expect 2-5% of immediate improvement in cognitive function, and the figure rises to 10% if you continue to use more than five weeks. A long-term clinical study of 307 patients confirmed that the effect lasts for up to 16 weeks after 4-6 weeks of use. BBB is currently conducting clinical trials with leading research institutes on how <neurogear> and <neurogear Pro> enhance cognitive abilities. Were there any techniques to stimulate deep brain in a non-invasive way? Among existing TMS, there is Deep TMS. It is a helmet type that uses a coil which wraps around the entire head to target the deep brain. Meanwhile, <neurogear> and <neurogear pro> use micro-magnetic field and have small and light body to mitigate psychological burden of users. To which diseases deep brain stimulation can be applied to in clinical trials? Deep Brain Stimulation (DBS) is mainly used for patients having impaired deep brain cause by Parkinson's disease or dementia. DBS is a surgical treatment that transplants a neurostimulator or brain pacemaker into the brain. It is a type of electrotherapy that uses the implant to send electrical stimulation to specific area of the brain. The FDA has approved DBS for the treatment of hand tremor, Parkinson's disease and dystonia. The treatment is used to alleviate tremor in patients with Parkinson's disease that cannot be controlled with medication. Can’t I use existing TMS to stimulate deep brain? TMS is designed to stimulate only one part of a brain with a single coil. <neurogear> and <neurogear pro> use multiple TMS coils to stimulate deep brain. BBB is currently pending a patent on coil placement. When <neurogear pro> be on the market? In early 2020, we’ll begin with acquiring certification on depression treatment and extend the area step by step to improvement of dementia, etc. What is the strong point of <neurogear> and <neurogear pro> in a word? It’s safe to use with low risk of side effects, easy to use intuitively, affordably priced compared to existing TMS, and has no physical stimulation so that users can be comfortably treated. FAQ:
  • 17. 2019. 04 (to do) Launch neurogearTM in US 2018. 10 Raised $15 million in Series B round 2018. 09 Selected as a National Project Supervision Institution “Bio Big-Data” 2017. 11 Launched elemarkTM dual check in Korea 2017. 08 Signed OEM contract with GenBody Inc. for supply of rapid test readers for arboviruses and DOA 2017. 06 Signed MOU with Korea University Guro Hospital to develop next-generation immunodiagnostic kit for cancer, myocardial infarction, and chronic disease 2017. 06 Signed MOU with Pusan University to construct infrastructure to commercialize research 2017. 04 Signed OEM contract with Philosys Inc. for supply of glucometers for hospital use 2016. 08 Signed agreement with KT for use of elemarkTM 2016. 08 Raised $5 million in Series A round 2016. 02 Signed strategic MOU with NOOM inc. targeting the mobile healthcare market 2015. 10 Winner of Zhongguancun Innoway “2015 Demo The World” in Smart Hardware Sector 2015. 08 Established regional office at NASA Ames Research Center, Silicon Valley, U.S.A. 2015. 05 Tech-In-Asia Award Winner @beGlobal Seoul 2015 2015. 04 Signed OEM contract with GreenCross MS for supply of in-vitro diagnostic devices for hospitals 2015. 01 Joined HAX Batch 6 program (HAX, Hardware startup accelerator based in Silicon Valley and Shenzhen) 2014. 10 Founded headquarters in Korea About company: © 2019 BBB inc. All Rights Reserved.
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  • 20. Business Contact KOREA : Taebom Kim taebeom.k@bbbtech.com USA : Ph D. Kyongsik Yun kyongsik@bbbtech.com PR Contact dike301@bbbtech.com Company Website bbbtech.com Seoul Office 14F, 26, Samseong-ro 85-gil, Gangnam-gu, Seoul, Republic of Korea © 2019 BBB inc. All Rights Reserved.
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