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Grace Australian Scientists HSC

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Grace Australian Scientists HSC

  1. 1. Barry Marshall
  2. 2. Medicine: Microbiology• Professor of clinical microbiology at the University of Western Australia• Microbiology: the branch of science that deals with microorganisms and their effects on other living organisms
  3. 3. Marshall’s Research• Together with Robin Warren showed that the bacterium Helicobacter pylori is the cause of most peptic ulcers.• Others before him had suggested similar theories but had failed to provide acceptable proof.• After failed attempts to infect piglets, Marshall drank a petri dish containing Helicobacter pylori
  4. 4. Impact on Society• Proved false years worth of beliefs that peptic ulcers were caused by stress, spicy foods and too much acid.• This has allowed for a breakthrough understanding the link between Helicobacter pylori and stomach cancer
  5. 5. Elizabeth Blackburn
  6. 6. Biological Researcher• Studies telomere, a structure at the end of chromosomes that protects the chromosome.• Also worked in the department of molecular biology.
  7. 7. Blackburn’s Research• Co-discovered telomerase, the enzyme that replenishes the telomere.
  8. 8. Blackburn recalls…• Carol had done this experiment, and we stood, just in the lab, and I remember sort of standing there, and she had this -- we call it a gel. Its an autoradiogram, because there was trace amounts of radioactivity that were used to develop an image of the separated DNA products of what turned out to be the telomerase enzyme reaction. I remember looking at it and just thinking, ‘Ah! This could be very big. This looks just right.’ It had a pattern to it. There was a regularity to it. There was something that was not just sort of garbage there, and that was really kind of coming through, even though we look back at it now, wed say, technically, there was this, that and the other, but it was a pattern shining through, and it just had this sort of sense, ‘Ah! Theres something real here.’

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