Identification of aberrant gene expression associated with aberrant promoter methylation in primordial germ cells between E13 and E16 rat F3 generation vinclozolin lineage
Similar to Identification of aberrant gene expression associated with aberrant promoter methylation in primordial germ cells between E13 and E16 rat F3 generation vinclozolin lineage
Similar to Identification of aberrant gene expression associated with aberrant promoter methylation in primordial germ cells between E13 and E16 rat F3 generation vinclozolin lineage (20)
Identification of Superclusters and Their Properties in the Sloan Digital Sky...
Identification of aberrant gene expression associated with aberrant promoter methylation in primordial germ cells between E13 and E16 rat F3 generation vinclozolin lineage
19. Summary
・PCA based unsupervisedunsupervised FE identified more genes
associated with both differential gene expression
and aberrant promoter methylation between E13
and E16 rat F3 generation vinclozolin lineage
・ Genes selected by PCA based unsupervisedunsupervised FE
were associated with various enrichments of
biological terms/concepts while none were
associated with those selected by ttest, limma, or
SAM based FE.
・ These suggested definitely the superiority of
unsupervisedunsupervised method toward supervised methods.