Presentation of Workshop on Technology for Healthcare and Healthy Lifestyle 2011

1. Imaging Biomarkers Automated
Structured Assembly Pipeline
(IB-ASAP)
CARLOS PÉREZ CASTILLO
www.cuantificacionquironvalencia.es
www.quiron.es

2. Digital Radiology
• The workspace of radiologists
has changed dramatically with
the development and Engineers
implementation of digital imaging Radiologists
Radiologist’s Workspace Technology
Multidisciplinary collaboration
New workflows
New challenges…

3. Imaging Biomarkers
 Objective characteristics extracted from
medical images
 Indicators and measures of normal
biological processes, diseases or
responses to therapeutic interventions
 Obtained before a lesion or biological
process becomes evident in the
radiological observation, by analyzing
properties and multivariate combination
of medical images and data
 Non invasive

4. Purpose: Workflow improvement

5. Brain: Morphometry
 Sequence optimization for brain morphometry

6. Brain: Functional MRI
Schizophrenia Brain injury Other diseases
Auditory Patients with Tumours, language
hallucinations mobility restriction disorders

7. Brain: Neuro-tractography
o Diffusion Tensor Imaging
o Neuronal Pathway
o Surgical Planning

8. Prostate: Diffusion
microscopic mobility of tissue water
Healthy tissue Pathological tissue

9. Prostate: Perfusion
Overlay a
vascular
permeability
parametric map
on anatomical
images

10. Prostate: Spectroscopy
Biochemical and metabolic profile of the gland.
Indicators of tumor presence :
-increased choline
- regional reduction in the levels of citrate

11. Data Pipeline

12. Workflow Description
DICOM
Organized Data Post- Post- Post-
images and
data storage preparation processing Processing Processing
data reception Notifications
and Algorithms Results Results
classification Execution Management Management

13. IB-ASAP
 The developments have provided
an innovative service that follows
an organized process, as a proper
technological support to leverage
the usability and ease the
development and
implementation of quantitative
imaging
 In addition, the software is fully
automated, vendor independent
and compatible with DICOM
standards

14. cvREMOD (CENIT-E)
 Quantify and understand the
mechanisms of cardiovascular
remodeling, improving the
knowledge of the
pathophysiological mechanisms
 Apply new imaging and modeling
technologies
 Help with diagnosis
 Optimize planning and
personalized treatment decisions
 Improve the monitoring and
prevention of future diseases

15. Thank you
 Supported by grants from SERAM (Sociedad
Española de Radiología Médica)
 The authors also thank the Radiology Department of
Hospital Quirón Valencia for their help and
continuous support with image acquisition and for
the clinical validation