HARNESSING PHARMA WORKFLOW WITH ELNs

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HARNESSING PHARMA
WORKFLOW WITH ELNs

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  • Merck implemented in 2000 Glaxo – 3500 R&D usersEli Lilly states productivity increase, ROI 5%
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  • Thick/thin client; thick client needs application install Internet Exporer is thin Thick need an application to run; Skype
  • HARNESSING PHARMA WORKFLOW WITH ELNs

    1. 1. HARNESSING PHARMA <br />WORKFLOW WITH ELNs<br /><ul><li>ELECTRONIC LABORATORY NOTEBOOKS</li></ul>WANDA HARTMANN OEHRLI<br />
    2. 2. Contents<br />20% growth rate per year <br />one of the fastestgrowing technologies<br />
    3. 3. ELN<br /><ul><li>A daily record-keeping of the pharma process that includes at least the content of a paper notebook
    4. 4. Helps to manage data from discovery to commercialization</li></li></ul><li>Pharma Workflow Example<br />
    5. 5. Importance of Notebooks<br />
    6. 6. Necessity of ELNsACCELERATION OF DRUG DISCOVERY!<br />
    7. 7. Current ELN Users<br />http://www.genengnews.com/articles/chitem.aspx?aid=2481<br />
    8. 8. Barriers to Implementation<br />
    9. 9. Resistance levels are low <br />
    10. 10. ELN Architecture<br />Database<br />Application/Web server <br />Software mainly <br />handles work process<br />flow<br />PDA laptop Computer<br />Copies of files will reside locally, short and long term on webservers and DB<br />
    11. 11. Most Popular Vendor <br />
    12. 12. Predictions<br />
    13. 13. Recommendations<br />:<br />
    14. 14. References<br />http://www.informationliberation.com/files/anthraxVaccine.jpg<br />http://www.healthsystem.virginia.edu/internet/uvamellon/images/DrugDiscovery.jpg<br />http://www.clinical-trials-info.com/wp-content/uploads/2009/02/drug-discovery-11.jpg<br />http://www.labtronics.com/Images/eln-small.jpg<br />http://en.wikipedia.org/wiki/Electronic_lab_notebook<br />http://acdlabs.typepad.com/my_weblog/2007/07/electronic-lab-.html<br />http://www.krackeler.com/graphics/0007/jpg/63001000a1.jpg<br />http://www.labtrack.com/files/q1_blank_screen.jpg<br />http://www.genengnews.com/articles/chitem.aspx?aid=1075<br />www.indiana.edu/~cheminfo/C571/ELNlecture20030825.ppt <br />http://www.scientific-computing.com/products/product_details.php?product_id=302<br />http://knol.google.com/k/shawn-mcclelland/electronic-lab-notebooks/3mhmqlqy4k0no/1#<br />http://www.scientificcomputing.com/Electronic-Laboratory-Notebooks-Enter-Mainstream-Informatics.aspx<br />Elliott, Michael H; Electronic Laboratory Notebooks: A Foundation for Scientific Knowledge Management Edition III; Atrium Research & Consulting LLC; Wilton, CT USA <br />http://www.measurementdevices.com/index.php?name=News&file=article&sid=1597<br />http://www.chem.agilent.com/en-US/Products/software/kalabieeln/Pages/default.aspx<br />http://www.streetinsider.com/Earnings/Symyx+Announces+Electronic+Laboratory+Notebook+and+LIMS+Partnership+With+Thermo+Fisher+Scientific/4491417.html<br />Some images are from Microsoft Clip Art<br />http://www.medicalnewstoday.com/articles/29934.php (resistance to ELN)<br />http://www.pr.com/press-release/44174 (LabTrak)<br />http://www.ddw-online.com/industrynews/124013/new_enterprise_electronic_lab_notebook.html (Symex notebook)<br />Networking will slow things down; cost http://pipeline.corante.com/archives/2008/02/07/write_it_down_write_it_down.php<br />http://www.genengnews.com/articles/chitem.aspx?aid=2481<br />http://www.phschool.com/science/science_news/articles/images/electron_runs_through_01.jpg<br />http://www.sxst.it/siti/sxst/sxst.nsf/seminari/cambridgesoft/ELN-Intro.pdf<br />Pharma company logs came from company websites.<br />Google Keyword searches<br /><ul><li>review of ELN electronic laboratory notebook
    15. 15. Market potential for electronic laboratory notebook at pharmaceutical companies
    16. 16. cost of electronic laboratory notebooks
    17. 17. cost of cambridgesofteln
    18. 18. I would like to acknowledge help from IT experts, friends and family who reviewed this presentation.</li>

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