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Synagis2010

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The Synagis program provides injections to our infant patients. I used many baby photos and graphics to make this a stunning and memorable teaching tool.

Published in: Health & Medicine
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Synagis2010

  1. 1. Synagis<br />
  2. 2. What is RSV?<br />Respiratory syncytial virus or RSV causes most children to develop a cold. Most children will catch RSV by age 2.<br />
  3. 3. What is RSV?<br />In Babies born prematurely or with certain lung and heart conditions, RSV can lead to pneumonia, and bronchiolitis. RSV is the #1 reason babies under 12months old in the US get hospitalized.<br />
  4. 4. RSV Epidemiology<br />In most parts of the country, the RSV season runs from fall into spring, but can occur at different times each year. <br />The CDC will track the virology each year and physicians continue to check for changes season to season.<br />
  5. 5. RSV TRANSMISSION<br />Transmitted by droplets, large particles, and fomites<br />RSV survives up to 6 hours on stethoscopes, and up to 12 hours on hard, nonporous surfaces.<br />Over 50% of medical personnel infected when RSV is prevalent in the community<br />Nosocomial infection remains to be a serious problem<br />
  6. 6. Synagis: Mechanism of Action<br />It is a monoclonal antibody that provides the specific antibodies that premature infants lack to help fight off RSV Disease<br />Blocks fusion of infected host cells (synctial formation)<br />Reduces viral infectivity and cell to cell transmission of the virus<br />
  7. 7. Dosing<br />
  8. 8. How Synagis is Supplied<br />Synagis is supplied in single dose vials as a preservative free , solution at 100mg/ml in 0.5ml and 1.0 ml , containing either 50mg or 100mg respectively, for IM injection. It is ready to use, no longer requires any prep<br />Upon receipt, Synagis should be stored 35.6 and 46.4 F in it original container<br />Do not, freeze, or shake vial or use beyond exp date.<br />
  9. 9. SynagisAdministration<br />Synagis should be administered in a dose of 15mg/Kg IM using 25 gauge 5/8 inch syringe in the anterolateral aspect of the thigh<br /><ul><li>The dose per month = patient weight (kg) x 15mg ÷100mg/ml of synagis
  10. 10. Injection volume over 1ml should be given as a divided dose</li></li></ul><li>In Summary……<br />RSV disease is universal and occurs in nearly all children two years of age<br />RSV is the leading cause of hospitalization in infants <than 1year.<br />Synagis is generally well tolerated and effective in preventing hospitalizations due to severe RSV infections.<br />
  11. 11. Questions<br />

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