Jackson Alan - 20th International Nutrition Congress 2013

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The 20th International Congress of Nutrition (ICN) hosted by the International Union of Nutritional Science (IUNS) took place on the 15th-20th September 2013, Granada, Spain. WCRF International held a 2-hour symposium on the Continuous Update Project (CUP) entitled ‘Food, Nutrition, Physical Activity and Cancer – Keeping the Evidence Current: WCRF/AICR Continuous Update Project (CUP).’ It included four presentations exploring the latest updates from the CUP.

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  • Please use the dd month yyyy format for the date for example 11 January 2008. The main title can be one or two lines long.
  • Changed is ‘toxic/infectious’ to ‘toxins and infections’
  • Jackson Alan - 20th International Nutrition Congress 2013

    1. 1. WCRF/AICR: Continuous Update Project (CUP) Future Implications Alan A Jackson University of Southampton, UK NIHR Southampton Biomedical Research Unit in Nutrition IUNS 20th International Congress of Nutrition “Joining Cultures Through Nutrition”
    2. 2. http://www.dietandcancerreport.org/cancer_resource_center/c up_summaries.php http://www.dietandcancerreport.org/cancer_resource_center/ downloads/cu/Breast-Cancer-2010-Report.pdf http://www.dietandcancerreport.org/cancer_resource_center/d ownloads/cu/Colorectal-Cancer-2011-Report.pdf http://www.dietandcancerreport.org/cancer_resource_center/ downloads/cu/Pancreatic-Cancer-2012-Report.pdf http://www.wcrf.org/PDFs/CUP-reports-SLRs/EndometrialCancer-2013-Report.pdf
    3. 3. Breast cancer 2010 Evidence for all factors was consistent with the conclusions from the Second Expert Report
    4. 4. Colorectal cancer 2011 • Foods containing dietary fibre upgraded from probable to convincing
    5. 5. Pancreatic cancer 2012 Foods containing folate downgraded from probable decreases risk
    6. 6. Endometrial cancer 2013 New conclusions for coffee and glycaemic load
    7. 7. Shift from exogenous toxins to endogenous factors
    8. 8. Previous mechanisms of carcinogenesis  External factors that act to produce cancer    Toxins Infections Structural   Adiposity Adult achieved height
    9. 9. Current mechanisms of carcinogenesis  External exposures substantially reduced  Extremely efficient systems for protection  Failure of protection against cancer   Internal control stressed beyond ability to cope Resilience vs allostatic load
    10. 10. Need for more integrated information  More detailed consideration cellular level interactions  Obesity  Energy  macronutrients  Other nutrients  Regulate and control processes  Understanding the nature of processes  DNA stability and repair  Energy flux  Inflammatory processes  Oxidative damage  Regulation of cell cycle
    11. 11. KEY CUP DATES  By 2015  CUP database complete and continually updated  By 2017  Review of Cancer Prevention Recommendations  Review of mechanisms  Review of breast cancer survivors  Implications for Policy

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