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Miscellaneous therapy successful for Helicobacter pylori eradication


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Miscellaneous therapy successful for Helicobacter pylori eradication

  1. 1. Miscellaneous therapysuccessful for Helicobacterpylori eradication
  2. 2. Miscellaneous therapy successful for Helicobacterpylori eradication 15-day treatment :- 5 initial days of lansoprazole 30 mg b.d., amoxicillin 1 g b.d., andmetronidazole 500 mg t.d.s.;- Days 6 to 10: lansoprazole 30 mg q.d.s. and metronidazole 500 mg t.d.s.;- Days 11 to 15: lansoprazole 30 mg b.d., clarithromycin 500 mg b.d. andmetronidazole 500 mg t.d.s. Each patient underwent an upper endoscopy before treatment, and a secondfollow-up endoscopy at least 4 weeks after therapy. The researchers found that success was defined on the basis of aneradication rate following a per-protocol analysis. The eradication rate with miscellaneous therapy was 94% in the per-protocol analysis Alimentary Pharmacology & TherapeuticsBiopsies before and after therapy were obtained for histological evaluationand rapid urease test. The doctors reported that 122 patients were enrolled, and 118 patientscompleted the study. The eradication rate for H. pylori with miscellaneous therapywas 94% in the per-protocol analysis , and 91% in the intention-to-treatanalysis.