QPR-Heptitis

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Quick Review of Pathology for clinicians and senior students.
Hepatitis.

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QPR-Heptitis

  1. 1. “ Within the mind are all the resources required for successful living. Ideas are present in the consciousness, which when released and given scope to grow and take shape, lead to successful events ” - Wings of Fire : An Autobiography of Dr. APJ Abdul Kalam .
  2. 2. Quick Pathology Review Shashidhar Venkatesh Murthy A/Prof.& Head of Pathology School of Medicine & Dentistry James Cook University Australia. Pathology of Hepatitis System : Hepatobiliary System Class : Liver disorders Topic : Hepatitis - Viral, Alcoholic & Other.
  3. 3. CPC 22- Liver - Hepatitis: CLI <ul><li>Liver: </li></ul><ul><li>Structure, Function tests & interpretation, Bilirubin metabolism, Jaundice. </li></ul><ul><li>Liver Failure – Hepatic coma. </li></ul><ul><li>Viral Hepatitis: </li></ul><ul><li>Specific (A,B,C,D,E) Non specific. </li></ul><ul><li>Acute, Chronic (CAH, CPH), Fulminant. </li></ul><ul><li>Complications: Cirrhosis macronodular, Hepatocellular ca. </li></ul><ul><li>Alcoholic Hepatitis: </li></ul><ul><li>Fatty change, Hepatitis, Cirrhosis (micronodular). </li></ul><ul><li>Clinical: </li></ul><ul><li>Fever, fatigue, jaundice, edema, ascitis, bleeding, harmone distrubances, hepatorenal syndrome. </li></ul><ul><li>Cirrhosis: </li></ul><ul><li>Definition, etiology, morphology, complications, ca. </li></ul>
  4. 4. <ul><li>Alcoholic hepatitis. </li></ul><ul><li>Hepatitis A. </li></ul><ul><li>α 1 Antitrypsin deficiency. </li></ul><ul><li>Hepatitis C </li></ul><ul><li>Hemochromatosis. </li></ul>?
  5. 5. <ul><li>Alcoholic fatty liver. </li></ul><ul><li>Fatty liver in obesity. </li></ul><ul><li>Alcoholic Cirrhosis. </li></ul><ul><li>Hepatitis C – steatosis. </li></ul><ul><li>Diabetes Type -I. </li></ul>?
  6. 6. <ul><li>Alcoholic fatty liver. </li></ul><ul><li>Alcoholic Hepatitis. </li></ul><ul><li>Alcoholic Cirrhosis. </li></ul><ul><li>Hepatitis C – steatosis. </li></ul><ul><li>Fulminant hepatitis. </li></ul>Diagnosis ?
  7. 7. <ul><li>Acute viral hepatitis. </li></ul><ul><li>Fulminant viral hepatitis. </li></ul><ul><li>Alcoholic Cirrhosis. </li></ul><ul><li>Viral Hepatitis with Cirrhosis. </li></ul><ul><li>Cardiac Schirrhosis. </li></ul>Diagnosis ?
  8. 8. <ul><li>Gall stones with obstruction. </li></ul><ul><li>Alcoholic Hepatitis. </li></ul><ul><li>Primary biliary cirrhosis. </li></ul><ul><li>Budd-Chiari Syndrome. </li></ul><ul><li>Massive Hepatic necrosis. </li></ul>?
  9. 9. <ul><li>Preeclampsia. </li></ul><ul><li>Acute Fatty Liver. </li></ul><ul><li>HELLP Syndrome. </li></ul><ul><li>Budd-Chiari Syndrome. </li></ul><ul><li>Massive Hepatic necrosis. </li></ul>What is the pathology in the Liver ?
  10. 10. <ul><li>Wilson’s Disease </li></ul><ul><li>Hereditary Hemochromatosis. </li></ul><ul><li>Primary Biliary Cirrhosis. </li></ul><ul><li>Budd-Chiari Syndrome. </li></ul><ul><li>Primary Sclerosing Cholangitis. </li></ul>?
  11. 11. <ul><li>Viral Hepatitis. </li></ul><ul><li>Primary Biliary cirrhosis. </li></ul><ul><li>Alcoholic hepatitis. </li></ul><ul><li>Fasciola hepatica infestation. </li></ul><ul><li>Gall stones & cholestasis. </li></ul>?
  12. 12. <ul><li>Cirrhosis of Liver </li></ul><ul><li>Viral Hepatitis. </li></ul><ul><li>Alcoholic hepatitis. </li></ul><ul><li>Gall stones & cholestasis. </li></ul><ul><li>Hemolytic Anemia. </li></ul>Liver Function Tests: What is the Diagnosis of Patient 2 ?
  13. 13. <ul><li>Viral Hepatitis. </li></ul><ul><li>Alcoholic fatty liver. </li></ul><ul><li>Alcoholic hepatitis. </li></ul><ul><li>Alcoholic cirrhosis. </li></ul><ul><li>Cholestasis. </li></ul>?
  14. 14. <ul><li>Alcoholic Hepatitis with fatty change. </li></ul><ul><li>Alcoholic fatty liver with infarction. </li></ul><ul><li>Alcoholic cirrhosis + Budd chiari. </li></ul><ul><li>Cirrhosis + Ascitis + encephalitis. </li></ul><ul><li>Alcoholic hepatosteatosis with necrosis. </li></ul>Diagnosis ?
  15. 15. <ul><li>Cirrhosis of Liver </li></ul><ul><li>Viral Hepatitis. </li></ul><ul><li>Alcoholic hepatitis. </li></ul><ul><li>Gall stones & cholestasis. </li></ul><ul><li>Hemolytic Anemia. </li></ul>Liver Function Tests: What is the Diagnosis of Patient 1 ?
  16. 16. <ul><li>α 1-Anti Trypsin Deficiency. </li></ul><ul><li>Gilbert’s syndrome. </li></ul><ul><li>MEN-Type 1 syndrome. </li></ul><ul><li>Hereditary Hemochromatosis. </li></ul><ul><li>Wilson’s disease. </li></ul>Diagnosis ?
  17. 17. <ul><li>Criggler-Najjar Syndrome </li></ul><ul><li>Gilbert’s syndrome. </li></ul><ul><li>MEN-Type 2. </li></ul><ul><li>Hereditary Hemochromatosis. </li></ul><ul><li>Primary Biliary Cirrhosis. </li></ul>Diagnosis ?
  18. 18. <ul><li>Post viral cirrhosis with liver failure. </li></ul><ul><li>Primary Biliary cirrhosis. </li></ul><ul><li>Cirrhosis + carcinoma. </li></ul><ul><li>Wilson’s disease with carcinoma. </li></ul><ul><li>Biliary Cirrhosis with carcinoma. </li></ul>Diagnosis ?
  19. 19. <ul><li>α 1-Anti Trypsin Deficiency. </li></ul><ul><li>Gilbert’s syndrome. </li></ul><ul><li>MEN-Type 1 syndrome. </li></ul><ul><li>Hereditary Hemochromatosis. </li></ul><ul><li>Wilson’s disease. </li></ul>Diagnosis ?
  20. 20. “ A person with belief never grovels before anyone, whining and whimpering that it’s all too much, that he lacks support, that he is being treated unfairly. Instead, such a person tackles problems head on and then affirms, I am greater than anything that can happen to me.” - Wings of Fire : An Autobiography of Dr. APJ Abdul Kalam.

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