There is substantial evidence on the relevant factors that motivate participation in human subject studies and the expectations of participants when sharing their health data for research. However, most human subject studies focus on participant eligibility and data collection, omitting even a rudimentary use of the factors that motivate participation. We illustrate an approach to use motivation to construct personalized stories and exemplify it by using a chatbot under development towards monitoring, analyzing, and influencing health study participation, engagement, and retention. Additionally, we discuss the new advantages, challenges, and unexplored avenues for research stemming from our approach. Cite this work in your research: Vlad Manea, Mads Schnoor Hansen, Ece Elbeyi, Katarzyna Wac. Towards Personalizing Participation in Health Studies. Workshop on Multimedia for Personal Health and Health Care, HealthMedia 2019. In conjunction with the ACM International Conference on Multimedia, MM 2019, Nice, France. Co-author. Presented by Semahat Ece Elbeyi, University of Copenhagen, Quality of Life Technologies Lab. Research funded by H2020 WellCo (769765). Workshop HealthMedia 2019 in conjunction with ACM MultiMedia 2019, Nice, France, October 2019.